[go: up one dir, main page]

ES434446A1 - Naphthoylamino alkyl phenoxy-alkyl-carboxylic acid derivatives - Google Patents

Naphthoylamino alkyl phenoxy-alkyl-carboxylic acid derivatives

Info

Publication number
ES434446A1
ES434446A1 ES434446A ES434446A ES434446A1 ES 434446 A1 ES434446 A1 ES 434446A1 ES 434446 A ES434446 A ES 434446A ES 434446 A ES434446 A ES 434446A ES 434446 A1 ES434446 A1 ES 434446A1
Authority
ES
Spain
Prior art keywords
alkyl
formula
group
signifies
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES434446A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES434446A1 publication Critical patent/ES434446A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/75—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for the preparation of derivatives of phenoxyalkoxycarboxylic acids of the general formula I **(See formula)** wherein R1 and R2 signify hydrogen or a lower alcohol group, Z signifies a hydroxyl group or a lower alkoxy group and n signifies numbers 1 or 2, characterized in that compounds of the general formula II are reacted **(See formula)** in which n has the meanings mentioned above, optionally after introduction of customary protecting groups for the amino or hydroxyl group, which in each case must be protected in an intermediate way, with a derivative of naphthoic acid III and with a compound of formula IV **(See formula)** in which R1, R2 and Z have the meanings indicated above and X represents a reactive group, or in the case where R1 and R2 signify lower alcohol groups, with a mixture of an aliphatic ketone, chloroform and an alkali metal hydroxide, optionally, the substituent Z is transformed, after condensation, and the compounds I obtained are transformed, if desired, into pharmacologically harmless salts. (Machine-translation by Google Translate, not legally binding)
ES434446A 1974-02-06 1975-02-04 Naphthoylamino alkyl phenoxy-alkyl-carboxylic acid derivatives Expired ES434446A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19742405622 DE2405622A1 (en) 1974-02-06 1974-02-06 NEW PHENOXYALKYLCARBONIC ACID DERIVATIVES AND METHOD FOR MANUFACTURING THE SAME

Publications (1)

Publication Number Publication Date
ES434446A1 true ES434446A1 (en) 1976-12-16

Family

ID=5906747

Family Applications (1)

Application Number Title Priority Date Filing Date
ES434446A Expired ES434446A1 (en) 1974-02-06 1975-02-04 Naphthoylamino alkyl phenoxy-alkyl-carboxylic acid derivatives

Country Status (19)

Country Link
JP (1) JPS50108249A (en)
AR (1) AR203228A1 (en)
AT (1) AT335439B (en)
BE (1) BE825176A (en)
CA (1) CA1043806A (en)
DD (1) DD120015A5 (en)
DE (1) DE2405622A1 (en)
DK (1) DK36575A (en)
ES (1) ES434446A1 (en)
FI (1) FI750292A7 (en)
FR (1) FR2259597B1 (en)
GB (1) GB1449586A (en)
HU (1) HU169491B (en)
IE (1) IE40585B1 (en)
IL (1) IL46543A0 (en)
NL (1) NL7501220A (en)
SE (1) SE7501083L (en)
SU (1) SU674670A3 (en)
ZA (1) ZA75703B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1812315A1 (en) * 1967-12-28 1969-12-04 Nippon Electric Co Electromechanical vibration device
US4214094A (en) 1977-03-30 1980-07-22 Fujisawa Pharmaceutical Co., Ltd. Substituted-phenyl substituted-alkyl ethers and the preparation thereof
DE2809377A1 (en) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh PHENOXYALKYL CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
JPS5649906B2 (en) * 1978-05-12 1981-11-25 Boehringer Mannheim Gmbh Manufacture of alphaa*44*44chlorobenzoylaminoo ethyl**phenoxy**isoethylacetic acid
US7838542B2 (en) * 2006-06-29 2010-11-23 Kinex Pharmaceuticals, Llc Bicyclic compositions and methods for modulating a kinase cascade
CA2666539A1 (en) * 2006-10-23 2008-05-02 Pfizer Inc. Substituted phenylmethyl bicyclocarboxyamide compounds
US9714238B2 (en) 2010-07-02 2017-07-25 Allergan, Inc. Therapeutic agents for ocular hypertension
WO2012003145A2 (en) 2010-07-02 2012-01-05 Allergan, Inc. Therapeutic agents for ocular hypertension

Also Published As

Publication number Publication date
BE825176A (en) 1975-08-04
ZA75703B (en) 1976-02-25
IE40585L (en) 1975-08-06
DD120015A5 (en) 1976-05-20
SE7501083L (en) 1975-08-07
FR2259597A1 (en) 1975-08-29
DE2405622A1 (en) 1975-08-14
GB1449586A (en) 1976-09-15
SU674670A3 (en) 1979-07-15
AR203228A1 (en) 1975-08-22
FR2259597B1 (en) 1980-01-04
CA1043806A (en) 1978-12-05
JPS50108249A (en) 1975-08-26
DK36575A (en) 1975-10-06
AU7701874A (en) 1976-07-01
IL46543A0 (en) 1975-04-25
AT335439B (en) 1977-03-10
HU169491B (en) 1976-12-28
NL7501220A (en) 1975-08-08
FI750292A7 (en) 1975-08-07
IE40585B1 (en) 1979-07-04
ATA85775A (en) 1976-07-15

Similar Documents

Publication Publication Date Title
ES407208A1 (en) Phenoxy-alkyl-carboxylic acid compounds
ES477741A1 (en) A procedure for preparing acetic acid derivatives. (Machine-translation by Google Translate, not legally binding)
ES434446A1 (en) Naphthoylamino alkyl phenoxy-alkyl-carboxylic acid derivatives
ES405022A1 (en) Novel n(6)-substituted adenosine compounds and therapeutic compositions
ES408274A1 (en) 2-(furfuryl-methyl)-6,7-benzomorphans and acid addition salts thereof
ES428818A1 (en) N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them
ES401589A1 (en) 2-(5'-nitro-2'-furyl)-thieno(2,3-d)pyridines and salts thereof
ES472276A1 (en) Cis-4a-phenyl-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines and pharmaceutical compositions containing them
ES418827A1 (en) 2-aminoindane derivatives
IE44184L (en) Imidazole derivatives
ES394967A1 (en) PROCEDURE FOR THE PREPARATION OF 3-ALCOHIL-5-ARYLOXIME-TILISOXAZOLES.
ES432224A1 (en) Production of benzenesulphonamides
ES401342A1 (en) Pyridine derivatives
ES452391A1 (en) PROCEDURE FOR THE PREPARATION OF NEW REPLACED ARILALCOHILAMINS.
ES389921A1 (en) N-(hydroxy-or methoxy-alkyl)-2-(n'-(hydroxy or methoxy-alkyl)-phenyl-amino)-imidazolines-(2) and salts thereof
ES346350A1 (en) Benzothiopyrone compounds
GB1420758A (en) Anti-ulcer compositions
ES397037A1 (en) Method of preparation of purine sugar derivatives
ES443357A1 (en) 1,4-benzodioxanes their methods of preparation and their application in therapeutics
ES442051A1 (en) Aminoglycosides
ES407933A2 (en) Nitrofuran and nitrothiophene derivatives
ES438481A1 (en) Triazole derivatives and processes for the production thereof
ES393259A1 (en) Amino-acid ester derivatives of 2h-chromen-5-ol
ES274907A1 (en) Iminodibenzyl derivatives
ES423746A1 (en) Procedure for preparing 2-aminoindane derivatives. (Machine-translation by Google Translate, not legally binding)