ES426618A1 - 6-aza-3h-1,4-benzodiazepines - Google Patents
6-aza-3h-1,4-benzodiazepinesInfo
- Publication number
- ES426618A1 ES426618A1 ES426618A ES426618A ES426618A1 ES 426618 A1 ES426618 A1 ES 426618A1 ES 426618 A ES426618 A ES 426618A ES 426618 A ES426618 A ES 426618A ES 426618 A1 ES426618 A1 ES 426618A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- atoms
- alcohol
- alkoxy
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BTQDZLVHRYXJDK-UHFFFAOYSA-N 3h-pyrido[3,2-e][1,4]diazepine Chemical class C1=NCC=NC2=CC=CN=C21 BTQDZLVHRYXJDK-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 12
- 125000003545 alkoxy group Chemical group 0.000 abstract 6
- 125000003158 alcohol group Chemical group 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Preparation procedure for compounds of the general formula **(See formula)** where n is the numbers 1 to 4, means a hydroxy group, an amino group, an alcohol group with 1 to 6 C atoms, an alkoxy group with 1 to 6 C atoms, a phenyl group or a substituted phenyl group with alcohol groups with 1 to 6 C atoms, with alkoxy groups with 1 to 6 C atoms, with trifluoromethyl, fluorine or chlorine, A means an oxygen or sulfur atom, an imino group or an alcohol-imino group with 1 to 6 C atoms or, in the case where R1 is a phenyl group or a substituted phenyl group, also two alkoxy groups with 1 to 6 C atoms each or an alcohol-dioxy group with 2 to 4 C atoms, or the entire group -C (R1) = A can also represent the cyano group, B means an oxygen or sulfur atom, an imino group or an alcohol-imino group with 1 to 6 C atoms, R2 means a hydrogen atom, a hydroxy group, an alcohol group with 1 to 6 C atoms, an alkoxy group with 1 to 6 C atoms, or the group -O- (CH2) nC (= A) -R1, Does not mean a nitrogen atom or a group NO, and the radicals R3 and R4, which are the same or different, and mean hydrogen, chlorine, fluorine, the trifluoromethyl group, alcohol groups with 1 to 6 C atoms or alkoxy groups with 1 to 6 C atoms, their tautomeric forms or isomers and their salts, characterized in that a compound of the formula **(See formula)** it is condensed, optionally with the addition of an acid fixing medium, with a compound of the formula **(See formula)** wherein R2 and B have the aforementioned meanings and Y is a hydroxyl group, a halogen atom, an alkoxy group, a mercapto group, an alloohyl-mercapto group, an amino group or an alcoholic-amino group. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT462873A AT331251B (en) | 1973-05-25 | 1973-05-25 | PROCESS FOR THE PREPARATION OF NEW 6-AZA-7-CHLORO-1,2-DIHYDRO-3H-1,4-BENZODIAZEPINES AND THE SALT THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES426618A1 true ES426618A1 (en) | 1976-07-01 |
Family
ID=3566375
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES426618A Expired ES426618A1 (en) | 1973-05-25 | 1974-05-24 | 6-aza-3h-1,4-benzodiazepines |
| ES426619A Expired ES426619A1 (en) | 1973-05-25 | 1974-05-24 | 6-aza-3h-1,4-benzodiazepines |
| ES426617A Expired ES426617A1 (en) | 1973-05-25 | 1974-05-24 | 6-aza-3h-1,4-benzodiazepines |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES426619A Expired ES426619A1 (en) | 1973-05-25 | 1974-05-24 | 6-aza-3h-1,4-benzodiazepines |
| ES426617A Expired ES426617A1 (en) | 1973-05-25 | 1974-05-24 | 6-aza-3h-1,4-benzodiazepines |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3900466A (en) |
| JP (1) | JPS5019767A (en) |
| AR (1) | AR200928A1 (en) |
| AT (1) | AT331251B (en) |
| BE (1) | BE815467A (en) |
| CA (1) | CA1035771A (en) |
| CH (1) | CH605942A5 (en) |
| DD (1) | DD111206A5 (en) |
| DE (1) | DE2425282A1 (en) |
| EG (1) | EG11352A (en) |
| ES (3) | ES426618A1 (en) |
| FR (1) | FR2230367B1 (en) |
| GB (1) | GB1410319A (en) |
| HU (1) | HU174561B (en) |
| NL (1) | NL7407015A (en) |
| RO (1) | RO63559A (en) |
| ZA (1) | ZA743348B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19710449A1 (en) * | 1997-03-13 | 1998-09-17 | Basf Ag | Process for the purification of sodium hydroxide solution |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3314941A (en) * | 1964-06-23 | 1967-04-18 | American Cyanamid Co | Novel substituted pyridodiazepins |
-
1973
- 1973-05-25 AT AT462873A patent/AT331251B/en not_active IP Right Cessation
-
1974
- 1974-05-08 US US468088A patent/US3900466A/en not_active Expired - Lifetime
- 1974-05-22 AR AR253867A patent/AR200928A1/en active
- 1974-05-22 FR FR7417836A patent/FR2230367B1/fr not_active Expired
- 1974-05-22 EG EG188A patent/EG11352A/en active
- 1974-05-22 BE BE6044605A patent/BE815467A/en unknown
- 1974-05-23 CA CA200,670A patent/CA1035771A/en not_active Expired
- 1974-05-23 DD DD178713A patent/DD111206A5/xx unknown
- 1974-05-24 HU HU74DE853A patent/HU174561B/en unknown
- 1974-05-24 ES ES426618A patent/ES426618A1/en not_active Expired
- 1974-05-24 CH CH714474A patent/CH605942A5/xx not_active IP Right Cessation
- 1974-05-24 ES ES426619A patent/ES426619A1/en not_active Expired
- 1974-05-24 ES ES426617A patent/ES426617A1/en not_active Expired
- 1974-05-24 DE DE19742425282 patent/DE2425282A1/en not_active Withdrawn
- 1974-05-24 NL NL7407015A patent/NL7407015A/xx not_active Application Discontinuation
- 1974-05-24 ZA ZA00743348A patent/ZA743348B/en unknown
- 1974-05-24 GB GB2330874A patent/GB1410319A/en not_active Expired
- 1974-05-24 RO RO7400078928A patent/RO63559A/en unknown
- 1974-05-24 JP JP49058658A patent/JPS5019767A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US3900466A (en) | 1975-08-19 |
| ATA462873A (en) | 1975-11-15 |
| EG11352A (en) | 1977-11-30 |
| CA1035771A (en) | 1978-08-01 |
| AR200928A1 (en) | 1974-12-27 |
| GB1410319A (en) | 1975-10-15 |
| JPS5019767A (en) | 1975-03-01 |
| FR2230367B1 (en) | 1978-03-24 |
| AT331251B (en) | 1976-08-10 |
| RO63559A (en) | 1978-07-15 |
| CH605942A5 (en) | 1978-10-13 |
| HU174561B (en) | 1980-02-28 |
| ES426617A1 (en) | 1976-12-16 |
| ES426619A1 (en) | 1977-01-01 |
| FR2230367A1 (en) | 1974-12-20 |
| ZA743348B (en) | 1975-05-28 |
| DE2425282A1 (en) | 1974-12-19 |
| DD111206A5 (en) | 1975-02-05 |
| AU6932574A (en) | 1975-11-27 |
| NL7407015A (en) | 1974-11-27 |
| BE815467A (en) | 1974-11-22 |
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