ES406250A1 - A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES406250A1 ES406250A1 ES406250A ES406250A ES406250A1 ES 406250 A1 ES406250 A1 ES 406250A1 ES 406250 A ES406250 A ES 406250A ES 406250 A ES406250 A ES 406250A ES 406250 A1 ES406250 A1 ES 406250A1
- Authority
- ES
- Spain
- Prior art keywords
- tetrazol
- translation
- preparing
- procedure
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000004299 tetrazol-5-yl group Chemical group [H]N1N=NC(*)=N1 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A procedure for preparing 2-decarboxy-2- [tetrazol-5-yl] prostaglandins of the formula: **(See formula)** where R is selected from the group consisting of (see formula) -alpha-hydroxy and (see formula); R2 and R3 are hydrogen; R1 is selected from the group consisting of hydrogen and lower alkyl; Y is selected from the group consisting of a single bond and a trans double bond; X and Z are each single bonds or are cis double bonds, such that when Z is a cis double bond, X is a cis double bond and Y is a trans double bond; characterized by reacting a compound of formula I above, wherein R, R1, X, Y and Z are as defined above, and R2 and are tetrahydropyranyl, with aqueous acetic acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17710271A | 1971-09-01 | 1971-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES406250A1 true ES406250A1 (en) | 1976-06-01 |
Family
ID=22647201
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES406250A Expired ES406250A1 (en) | 1971-09-01 | 1972-08-31 | A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding) |
| ES417557A Expired ES417557A1 (en) | 1971-09-01 | 1973-08-03 | A procedure for preparing replaced ciclopentan derivatives. (Machine-translation by Google Translate, not legally binding) |
| ES417558A Expired ES417558A1 (en) | 1971-09-01 | 1973-08-03 | A procedure for preparing bromide of 4- (tetrazol-5-il) butiltripenylphosphonium. (Machine-translation by Google Translate, not legally binding) |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417557A Expired ES417557A1 (en) | 1971-09-01 | 1973-08-03 | A procedure for preparing replaced ciclopentan derivatives. (Machine-translation by Google Translate, not legally binding) |
| ES417558A Expired ES417558A1 (en) | 1971-09-01 | 1973-08-03 | A procedure for preparing bromide of 4- (tetrazol-5-il) butiltripenylphosphonium. (Machine-translation by Google Translate, not legally binding) |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5724348B2 (en) |
| AR (4) | AR197304A1 (en) |
| AT (3) | AT335079B (en) |
| CA (1) | CA978939A (en) |
| DK (1) | DK144730C (en) |
| ES (3) | ES406250A1 (en) |
| FI (1) | FI55497C (en) |
| FR (3) | FR2283147A1 (en) |
| IL (3) | IL48544A (en) |
| PH (3) | PH10023A (en) |
| SE (4) | SE409032B (en) |
| ZA (1) | ZA725827B (en) |
-
1972
- 1972-08-22 IL IL48544A patent/IL48544A/en unknown
- 1972-08-22 IL IL40183A patent/IL40183A/en unknown
- 1972-08-24 ZA ZA725827A patent/ZA725827B/en unknown
- 1972-08-29 PH PH13850A patent/PH10023A/en unknown
- 1972-08-29 AT AT743472A patent/AT335079B/en not_active IP Right Cessation
- 1972-08-29 AT AT51974*7A patent/AT327219B/en not_active IP Right Cessation
- 1972-08-29 AT AT51974*A patent/ATA51974A/en not_active IP Right Cessation
- 1972-08-30 FI FI2387/72A patent/FI55497C/en active
- 1972-08-30 SE SE7211233A patent/SE409032B/en unknown
- 1972-08-31 AR AR243845A patent/AR197304A1/en active
- 1972-08-31 ES ES406250A patent/ES406250A1/en not_active Expired
- 1972-08-31 DK DK430772A patent/DK144730C/en not_active IP Right Cessation
- 1972-08-31 CA CA150,669A patent/CA978939A/en not_active Expired
- 1972-09-01 JP JP8784872A patent/JPS5724348B2/ja not_active Expired
-
1973
- 1973-06-22 AR AR248681A patent/AR199784A1/en active
- 1973-06-22 AR AR248683A patent/AR199574A1/en active
- 1973-06-22 AR AR248682A patent/AR199573A1/en active
- 1973-08-03 ES ES417557A patent/ES417557A1/en not_active Expired
- 1973-08-03 ES ES417558A patent/ES417558A1/en not_active Expired
-
1974
- 1974-06-03 PH PH15888A patent/PH10443A/en unknown
- 1974-06-03 PH PH15889A patent/PH10416A/en unknown
-
1975
- 1975-11-26 FR FR7536205A patent/FR2283147A1/en active Granted
- 1975-11-26 FR FR7536203A patent/FR2283136A1/en active Granted
- 1975-11-26 FR FR7536204A patent/FR2283134A1/en active Granted
- 1975-11-26 IL IL48544A patent/IL48544A0/en unknown
-
1976
- 1976-06-11 SE SE7606691A patent/SE424185B/en unknown
- 1976-06-11 SE SE7606690A patent/SE421526B/en unknown
- 1976-06-11 SE SE7606689A patent/SE421525B/en unknown
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