ES405212A1 - Procedure for the preparation of new pirido (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new pirido (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES405212A1 ES405212A1 ES405212A ES405212A ES405212A1 ES 405212 A1 ES405212 A1 ES 405212A1 ES 405212 A ES405212 A ES 405212A ES 405212 A ES405212 A ES 405212A ES 405212 A1 ES405212 A1 ES 405212A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- radicals
- general formula
- pyrimidines
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KZKRRZFCAYOXQE-UHFFFAOYSA-N 1$l^{2}-azinane Chemical group C1CC[N]CC1 KZKRRZFCAYOXQE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 230000021235 carbamoylation Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- -1 morpholino, thiomorpholino, 1-oxidothiomorpholino, 1,1-dioxidothiomorpholino Chemical group 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 159000000017 pyrido[3,2-d]pyrimidines Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedure for the preparation of new pyrido [3,2-d] pyrimidines of the general formula I, **(See formula)** in which one of the radicals R1 or R2 means the piperazine radical and the other of the radicals R1 or R2 represents a morpholino, thiomorpholino, 1-oxidothiomorpholino, 1,1-dioxidothiomorpholino or piperidino radical, possibly substituted by a lower alcohol radical, a piperazino radical optionally substituted in position 4 by a carbamoyl or lower alcohol radical, a dialkanolamino or alcohol-diamine amino group; and R3 signifies a hydrogen atom or the methyl group, as well as its physiologically compatible acid addition salts, characterized in that a compound of the general formula II is deacylated. **(See formula)** where R3 is as initially defined, one of the radicals R4 or R5 represents a piperazine radical substituted in position 4 by an acyl radical and the other of the radicals R4 or R5 has the initially mentioned meanings for R1 or R2; and, in case a compound of the general formula I is obtained, in which R1 and/or R2 represent free piperazine groups, these are subjected, if desired, to carbamoylation and/or a compound obtained from the general formula I is transformed, if desired, in its physiologically compatible salts with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712117657 DE2117657B2 (en) | 1971-04-10 | 1971-04-10 | PYRIDO SQUARE BRACKET ON 3.2-ANGLE BRACKET FOR PYRIMIDINE |
| DE19722208534 DE2208534A1 (en) | 1972-02-23 | 1972-02-23 | Pyrido(3,2-d)pyrimidines - anticoagulants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES405212A1 true ES405212A1 (en) | 1976-01-01 |
Family
ID=25760958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES405212A Expired ES405212A1 (en) | 1971-04-10 | 1972-07-27 | Procedure for the preparation of new pirido (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding) |
Country Status (3)
| Country | Link |
|---|---|
| ES (1) | ES405212A1 (en) |
| PL (2) | PL84566B1 (en) |
| SU (1) | SU492089A3 (en) |
-
1972
- 1972-04-08 PL PL17525772A patent/PL84566B1/pl unknown
- 1972-04-08 PL PL15461972A patent/PL83548B1/pl unknown
- 1972-07-27 ES ES405212A patent/ES405212A1/en not_active Expired
-
1973
- 1973-11-02 SU SU1967382A patent/SU492089A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| PL84566B1 (en) | 1976-04-30 |
| SU492089A3 (en) | 1975-11-15 |
| PL83548B1 (en) | 1975-12-31 |
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