ES386969A1 - Method for preparing biologically active substituted amidines - Google Patents
Method for preparing biologically active substituted amidinesInfo
- Publication number
- ES386969A1 ES386969A1 ES386969A ES386969A ES386969A1 ES 386969 A1 ES386969 A1 ES 386969A1 ES 386969 A ES386969 A ES 386969A ES 386969 A ES386969 A ES 386969A ES 386969 A1 ES386969 A1 ES 386969A1
- Authority
- ES
- Spain
- Prior art keywords
- biologically active
- active substituted
- formula
- substituted amidines
- preparing biologically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001409 amidines Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 1-N-substituted amidinourea Chemical class 0.000 abstract 1
- SQSPRWMERUQXNE-UHFFFAOYSA-N Guanylurea Chemical compound NC(=N)NC(N)=O SQSPRWMERUQXNE-UHFFFAOYSA-N 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Method for preparing an amidinourea of formula (I): ** (See formula) ** or an acid addition salt thereof, wherein R1 and R2 are halogen or nitrile, and at least one of R1 and R2 is halogen, characterized in that a 1-N-substituted amidinourea of the formula: ** (See formula) ** or an acid addition salt thereof, where R1 and R2 are as defined above; R is a hydrogen atom, an aryl group, or an alcohol group; and A is a hydrogen atom or the group CO.B, where B is an aryl group. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB32370 | 1970-01-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES386969A1 true ES386969A1 (en) | 1973-04-16 |
Family
ID=9702371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES386969A Expired ES386969A1 (en) | 1970-01-02 | 1970-12-31 | Method for preparing biologically active substituted amidines |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE761075A (en) |
| CH (1) | CH555325A (en) |
| DK (1) | DK128494C (en) |
| ES (1) | ES386969A1 (en) |
| GB (1) | GB1336871A (en) |
| NL (1) | NL7019013A (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL37047A0 (en) * | 1970-06-30 | 1971-08-25 | Wellcome Found | Substituted amidines,their preparation and pharmaceutical compositions containing them |
| DE4412079A1 (en) * | 1993-08-18 | 1995-02-23 | Bayer Ag | N-Cyanoaryl-nitrogen-heterocycles |
| US5681794A (en) * | 1993-08-18 | 1997-10-28 | Bayer Aktiengesellschaft | N-cyanoaryl-nitrogen heterocycles |
| ES2110667T3 (en) * | 1993-08-18 | 1998-02-16 | Bayer Ag | N-CIANOARIL-NITROGENATED HETEROCICLES. |
| DE19737463A1 (en) * | 1997-08-28 | 1999-03-04 | Hoechst Marion Roussel De Gmbh | Use of inhibitors of the sodium-hydrogen exchanger for the manufacture of a medicament for the treatment of diseases caused by protozoa |
-
1970
- 1970-12-23 GB GB1336871D patent/GB1336871A/en not_active Expired
- 1970-12-29 DK DK661770A patent/DK128494C/en active
- 1970-12-30 NL NL7019013A patent/NL7019013A/xx unknown
- 1970-12-30 BE BE761075A patent/BE761075A/en unknown
- 1970-12-31 ES ES386969A patent/ES386969A1/en not_active Expired
-
1971
- 1971-01-04 CH CH1371A patent/CH555325A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH555325A (en) | 1974-10-31 |
| DK128494C (en) | 1974-09-23 |
| NL7019013A (en) | 1971-07-06 |
| GB1336871A (en) | 1973-11-14 |
| DK128494B (en) | 1974-05-13 |
| BE761075A (en) | 1971-06-30 |
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