EP1578910A4 - Nitrilases - Google Patents

Nitrilases

Info

Publication number: EP1578910A4
Authority: EP; European Patent Office
Prior art keywords: nitrilases
Prior art date: 2001-06-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02780877A

Other languages

German (de)

French (fr)

Other versions

EP1578910A2 (en

Inventor

Grace Desantis

Jennifer Ann Chaplin

David Paul Weiner

Aileen Milan

Ellen Chi

Jay M Short

Mark Madden

Mark Burk

Dan Robertson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

BASF Enzymes LLC

Original Assignee

Verenium Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-21

Filing date

2002-05-15

Publication date

2008-06-04

2002-05-15 Application filed by Verenium Corp filed Critical Verenium Corp

2002-05-15 Priority to EP10190401.9A priority Critical patent/EP2319919B1/en

2002-05-15 Priority to EP10189100.0A priority patent/EP2327765B1/en

2002-05-15 Priority to EP20100190399 priority patent/EP2327767B1/en

2002-05-15 Priority to EP08075753A priority patent/EP2039762A3/en

2002-05-15 Priority to EP10190397.9A priority patent/EP2327766B1/en

2005-09-28 Publication of EP1578910A2 publication Critical patent/EP1578910A2/en

2008-06-04 Publication of EP1578910A4 publication Critical patent/EP1578910A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
- C12P13/004—Cyanohydrins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Analytical Chemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Processing Of Solid Wastes (AREA)
Treatment Of Sludge (AREA)

EP02780877A 2001-06-21 2002-05-15 Nitrilases Withdrawn EP1578910A4 (en)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
EP10190401.9A EP2319919B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP10189100.0A EP2327765B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP20100190399 EP2327767B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP08075753A EP2039762A3 (en)	2001-06-21	2002-05-15	Nitralases
EP10190397.9A EP2327766B1 (en)	2001-06-21	2002-05-15	Nitrilases

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US30018901P	2001-06-21	2001-06-21
US300189P		2001-06-21
US30900601P	2001-07-30	2001-07-30
US309006P		2001-07-30
US35133602P	2002-01-22	2002-01-22
US351336P		2002-01-22
PCT/US2002/015983 WO2003000840A2 (en)	2001-06-21	2002-05-15	Nitrilases

Related Child Applications (5)

Application Number	Title	Priority Date	Filing Date
EP08075753A Division EP2039762A3 (en)	2001-06-21	2002-05-15	Nitralases
EP10190401.9A Division EP2319919B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP10189100.0A Division EP2327765B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP20100190399 Division EP2327767B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP10190397.9A Division EP2327766B1 (en)	2001-06-21	2002-05-15	Nitrilases

Publications (2)

Publication Number	Publication Date
EP1578910A2 EP1578910A2 (en)	2005-09-28
EP1578910A4 true EP1578910A4 (en)	2008-06-04

Family

ID=27404717

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
EP10190397.9A Expired - Lifetime EP2327766B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP08075753A Withdrawn EP2039762A3 (en)	2001-06-21	2002-05-15	Nitralases
EP10189100.0A Expired - Lifetime EP2327765B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP02780877A Withdrawn EP1578910A4 (en)	2001-06-21	2002-05-15	Nitrilases
EP20100190399 Expired - Lifetime EP2327767B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP10190401.9A Expired - Lifetime EP2319919B1 (en)	2001-06-21	2002-05-15	Nitrilases

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
EP10190397.9A Expired - Lifetime EP2327766B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP08075753A Withdrawn EP2039762A3 (en)	2001-06-21	2002-05-15	Nitralases
EP10189100.0A Expired - Lifetime EP2327765B1 (en)	2001-06-21	2002-05-15	Nitrilases

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
EP20100190399 Expired - Lifetime EP2327767B1 (en)	2001-06-21	2002-05-15	Nitrilases
EP10190401.9A Expired - Lifetime EP2319919B1 (en)	2001-06-21	2002-05-15	Nitrilases

Country Status (6)

Country	Link
EP (6)	EP2327766B1 (en)
JP (2)	JP4405258B2 (en)
AU (2)	AU2006252258B2 (en)
CA (2)	CA2445046C (en)
DK (3)	DK2327767T3 (en)
WO (1)	WO2003000840A2 (en)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1141275B1 (en)	1999-01-05	2009-08-12	Trustees Of Boston University	Improved nucleic acid cloning
US20040005673A1 (en)	2001-06-29	2004-01-08	Kevin Jarrell	System for manipulating nucleic acids
US7608445B1 (en)	1999-12-29	2009-10-27	Verenium Corporation	Nitrilases, nucleic acids encoding them and methods for making and using them
US7521216B2 (en)	1999-12-29	2009-04-21	Verenium Corporation	Nitrilases and methods for making and using them
US7300775B2 (en)	1999-12-29	2007-11-27	Verenium Corporation	Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US20040002147A1 (en) *	1999-12-29	2004-01-01	Desantis Grace	Nitrilases
US7435562B2 (en)	2000-07-21	2008-10-14	Modular Genetics, Inc.	Modular vector systems
US7932064B2 (en)	2002-06-13	2011-04-26	Verenium Corporation	Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid
CN100445375C (en) *	2003-02-27	2008-12-24	巴斯福股份公司	Modified nitrilases and their use in methods for producing carboxylic acids
TW200519106A (en)	2003-05-02	2005-06-16	Novartis Ag	Organic compounds
US7198926B2 (en)	2003-05-08	2007-04-03	E. I. Du Pont De Nemours And Company	Preparation of (E)- and (Z)-2-methyl-2-butenoic acids
GB0401334D0 (en)	2004-01-21	2004-02-25	Novartis Ag	Organic compounds
GB0411056D0 (en)	2004-05-18	2004-06-23	Novartis Ag	Organic compounds
GT200500281A (en)	2004-10-22	2006-04-24	Novartis Ag	ORGANIC COMPOUNDS.
EP1817413B1 (en)	2004-11-11	2012-01-04	Modular Genetics, Inc.	Oligonucleotide ladder assembly and system for generating molecular diversity
GB0426164D0 (en)	2004-11-29	2004-12-29	Novartis Ag	Organic compounds
GB0507577D0 (en)	2005-04-14	2005-05-18	Novartis Ag	Organic compounds
GB0510390D0 (en)	2005-05-20	2005-06-29	Novartis Ag	Organic compounds
KR20080049113A (en)	2005-10-21	2008-06-03	노파르티스 아게	Human Antibodies and Therapeutic Uses Against IL-13
WO2007094885A2 (en) *	2005-12-07	2007-08-23	Southern Methodist University	Identification of a nitrilase from b. japonicum by rational genome mining and methods of use
GB0601951D0 (en)	2006-01-31	2006-03-15	Novartis Ag	Organic compounds
CA2649215A1 (en)	2006-04-21	2007-11-01	Novartis Ag	2,6,9-trisubstituted purine compounds as adenosine aza receptor modulators
CN100500832C (en) *	2006-04-29	2009-06-17	浙江工业大学	Bacillus subtilis ZJB-063 and its application
KR20090073121A (en)	2006-09-29	2009-07-02	노파르티스 아게	Pyrazolopyrimidines as PI3 'Lipid Kinase Inhibitors
DK2104535T3 (en)	2007-01-10	2011-04-04	Irm Llc	Compounds and Compositions as Channel Activating Protease Inhibitors
EP2115153B1 (en) *	2007-03-01	2013-06-05	BP Corporation North America Inc.	Nitrilases, nucleic acids encoding them and methods for making and using them
DE602008005140D1 (en)	2007-05-07	2011-04-07	Novartis Ag	ORGANIC CONNECTIONS
CA2707857C (en)	2007-12-10	2016-09-13	Novartis Ag	Spirocyclic amiloride analogues
JP5165393B2 (en) *	2008-01-10	2013-03-21	旭化成ケミカルズ株式会社	Method for producing glycolic acid or ammonium glycolate
PT2231642E (en)	2008-01-11	2014-03-12	Novartis Ag	Pyrimidines as kinase inhibitors
US8268834B2 (en)	2008-03-19	2012-09-18	Novartis Ag	Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
ES2535736T3 (en)	2008-06-10	2015-05-14	Novartis Ag	Pyrazine derivatives as epithelial sodium channel blockers
US20110281917A1 (en)	2009-01-29	2011-11-17	Darrin Stuart	Substituted Benzimidazoles for the Treatment of Astrocytomas
US8389526B2 (en)	2009-08-07	2013-03-05	Novartis Ag	3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
WO2011018454A1 (en)	2009-08-12	2011-02-17	Novartis Ag	Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
IN2012DN01961A (en)	2009-08-17	2015-08-21	Intellikine Llc
MX2012002179A (en)	2009-08-20	2012-03-16	Novartis Ag	Heterocyclic oxime compounds.
WO2011050325A1 (en)	2009-10-22	2011-04-28	Vertex Pharmaceuticals Incorporated	Compositions for treatment of cystic fibrosis and other chronic diseases
US8247436B2 (en)	2010-03-19	2012-08-21	Novartis Ag	Pyridine and pyrazine derivative for the treatment of CF
WO2012034095A1 (en)	2010-09-09	2012-03-15	Irm Llc	Compounds and compositions as trk inhibitors
UY33597A (en)	2010-09-09	2012-04-30	Irm Llc	COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF THE TRK
US8372845B2 (en)	2010-09-17	2013-02-12	Novartis Ag	Pyrazine derivatives as enac blockers
WO2012107500A1 (en)	2011-02-10	2012-08-16	Novartis Ag	[1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
WO2012116237A2 (en)	2011-02-23	2012-08-30	Intellikine, Llc	Heterocyclic compounds and uses thereof
WO2012116217A1 (en)	2011-02-25	2012-08-30	Irm Llc	Compounds and compositions as trk inhibitors
GB201111639D0 (en) *	2011-07-07	2011-08-24	Waterford Inst Technology	A process for producing amides and acids using a nitrile-metabolising enzyme
GB201111637D0 (en) *	2011-07-07	2011-08-24	Waterford Inst Technology	A process for producing amides and acids using a nitrile-metabolising enzyme
US8883819B2 (en)	2011-09-01	2014-11-11	Irm Llc	Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
US9062045B2 (en)	2011-09-15	2015-06-23	Novartis Ag	Triazolopyridine compounds
WO2013038373A1 (en)	2011-09-16	2013-03-21	Novartis Ag	Pyridine amide derivatives
WO2013038378A1 (en)	2011-09-16	2013-03-21	Novartis Ag	Pyridine amide derivatives
WO2013038381A1 (en)	2011-09-16	2013-03-21	Novartis Ag	Pyridine/pyrazine amide derivatives
CN103946221B (en)	2011-09-16	2016-08-03	诺华股份有限公司	Heterocyclic compounds for the treatment of cystic fibrosis
JP6165733B2 (en)	2011-09-16	2017-07-19	ノバルティスアーゲー	N-substituted heterocyclylcarboxamides
WO2013078440A2 (en)	2011-11-23	2013-05-30	Intellikine, Llc	Enhanced treatment regimens using mtor inhibitors
CN102363775B (en) *	2011-11-30	2014-04-02	重庆大学	Method for purifying nitrilase
US8809340B2 (en)	2012-03-19	2014-08-19	Novartis Ag	Crystalline form
MX371119B (en)	2012-04-03	2020-01-17	Novartis Ag	Combination products with tyrosine kinase inhibitors and their use.
US9073921B2 (en)	2013-03-01	2015-07-07	Novartis Ag	Salt forms of bicyclic heterocyclic derivatives
WO2014151147A1 (en)	2013-03-15	2014-09-25	Intellikine, Llc	Combination of kinase inhibitors and uses thereof
TW201605450A (en)	2013-12-03	2016-02-16	諾華公司	Combination of Mdm2 inhibitor and BRAF inhibitor and their use
BR112016023967A2 (en)	2014-04-24	2017-08-15	Novartis Ag	pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
US10004732B2 (en)	2014-04-24	2018-06-26	Novartis Ag	Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2015162456A1 (en)	2014-04-24	2015-10-29	Novartis Ag	Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2016011658A1 (en)	2014-07-25	2016-01-28	Novartis Ag	Combination therapy
MX373272B (en)	2014-07-31	2020-04-16	Novartis Ag	Combination therapy
CN104774825B (en) *	2015-03-23	2017-11-07	浙江工业大学	Nitrilase mutants and its application
CN108368033B (en) *	2015-11-19	2021-05-04	Gsp作物科学有限公司	A kind of method for preparing tristrobin
CN106854673B (en) *	2016-12-23	2020-05-15	枣庄市杰诺生物酶有限公司	Method for preparing R-o-chloromandelic acid by using nitrilase engineering bacteria
CN109111043B (en) *	2018-09-16	2021-11-09	苏州渭中科技发展有限公司	Treatment method of high-salt high-COD wastewater
WO2020152104A2 (en) *	2019-01-22	2020-07-30	Basf Se	Method for production of 4-cyano benzoic acid or salts thereof
WO2020250116A1 (en)	2019-06-10	2020-12-17	Novartis Ag	Pyridine and pyrazine derivative for the treatment of cf, copd, and bronchiectasis
JP2022547427A (en)	2019-08-28	2022-11-14	ノバルティスアーゲー	Substituted 1,3-phenylheteroaryl derivatives and their use in treating disease
TW202140550A (en)	2020-01-29	2021-11-01	瑞士商諾華公司	Methods of treating an inflammatory or obstructive airway disease using anti-tslp antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0780471A2 (en) *	1995-07-31	1997-06-25	Nitto Chemical Industry Co., Ltd.	Novel nitrilase gene

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US813998A (en)	1903-10-31	1906-02-27	Rail Joint Co	Insulated rail-joint.
US4946778A (en)	1987-09-21	1990-08-07	Genex Corporation	Single polypeptide chain binding molecules
WO1991016427A1 (en)	1990-04-24	1991-10-31	Stratagene	Methods for phenotype creation from multiple gene populations
US5331573A (en)	1990-12-14	1994-07-19	Balaji Vitukudi N	Method of design of compounds that mimic conformational features of selected peptides
JP2676568B2 (en)	1991-06-26	1997-11-17	日東化学工業株式会社	Method for producing R (-)-mandelic acid and its derivatives
US5241087A (en)	1992-03-09	1993-08-31	Bend Research, Inc.	Enantiomeric enrichment of cyanohydrins
US5631280A (en)	1995-03-29	1997-05-20	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
US6030779A (en)	1995-07-18	2000-02-29	Diversa Corporation	Screening for novel bioactivities
US5958672A (en)	1995-07-18	1999-09-28	Diversa Corporation	Protein activity screening of clones having DNA from uncultivated microorganisms
US5965408A (en)	1996-07-09	1999-10-12	Diversa Corporation	Method of DNA reassembly by interrupting synthesis
US5939250A (en)	1995-12-07	1999-08-17	Diversa Corporation	Production of enzymes having desired activities by mutagenesis
DE19848129A1 (en)	1998-10-19	2000-04-20	Basf Ag	New nucleic acid sequence encoding Alcaligenes faecalis nitrilase polypeptide useful for converting racemic nitriles to chiral carboxylic acids
DE19929365A1 (en)	1999-06-25	2000-12-28	Basf Lynx Bioscience Ag	New genes from Corynebacterium glutamicum, useful for modifying cells for production of primary or secondary metabolites, e.g. amino or fatty acids
US7300775B2 (en) *	1999-12-29	2007-11-27	Verenium Corporation	Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
WO2001055074A1 (en)	2000-01-25	2001-08-02	Kaneka Corporation	Process for producing optically active carboxylic acid substituted in 2-position
WO2014205447A2 (en)	2013-06-21	2014-12-24	Bio-Rad Laboratories, Inc.	Microfluidic system with fluid pickups

2002
- 2002-05-15 DK DK10190399.5T patent/DK2327767T3/en active
- 2002-05-15 EP EP10190397.9A patent/EP2327766B1/en not_active Expired - Lifetime
- 2002-05-15 WO PCT/US2002/015983 patent/WO2003000840A2/en not_active Ceased
- 2002-05-15 DK DK10189100.0T patent/DK2327765T3/en active
- 2002-05-15 CA CA002445046A patent/CA2445046C/en not_active Expired - Lifetime
- 2002-05-15 EP EP08075753A patent/EP2039762A3/en not_active Withdrawn
- 2002-05-15 EP EP10189100.0A patent/EP2327765B1/en not_active Expired - Lifetime
- 2002-05-15 JP JP2003507227A patent/JP4405258B2/en not_active Expired - Fee Related
- 2002-05-15 DK DK10190397.9T patent/DK2327766T3/en active
- 2002-05-15 CA CA2677781A patent/CA2677781C/en not_active Expired - Lifetime
- 2002-05-15 EP EP02780877A patent/EP1578910A4/en not_active Withdrawn
- 2002-05-15 EP EP20100190399 patent/EP2327767B1/en not_active Expired - Lifetime
- 2002-05-15 EP EP10190401.9A patent/EP2319919B1/en not_active Expired - Lifetime
2006
- 2006-12-22 AU AU2006252258A patent/AU2006252258B2/en not_active Ceased
2007
- 2007-05-01 JP JP2007121226A patent/JP4405528B2/en not_active Expired - Fee Related
2010
- 2010-08-10 AU AU2010212259A patent/AU2010212259B2/en not_active Ceased

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0780471A2 (en) *	1995-07-31	1997-06-25	Nitto Chemical Industry Co., Ltd.	Novel nitrilase gene

Also Published As

Publication number	Publication date
EP2327767B1 (en)	2015-04-29
EP2327765B1 (en)	2015-04-01
DK2327766T3 (en)	2016-03-07
JP4405258B2 (en)	2010-01-27
AU2010212259B2 (en)	2012-11-29
EP2327765A1 (en)	2011-06-01
AU2006252258A1 (en)	2007-01-25
DK2327765T3 (en)	2015-07-13
EP2327767A1 (en)	2011-06-01
AU2010212259A1 (en)	2010-09-02
CA2445046A1 (en)	2003-01-03
EP2039762A2 (en)	2009-03-25
JP2005509407A (en)	2005-04-14
EP2039762A3 (en)	2009-07-29
JP2007252382A (en)	2007-10-04
WO2003000840A3 (en)	2007-11-15
EP2327766B1 (en)	2015-12-02
CA2677781A1 (en)	2003-01-03
EP2319919B1 (en)	2015-08-12
JP4405528B2 (en)	2010-01-27
CA2677781C (en)	2013-01-29
EP1578910A2 (en)	2005-09-28
EP2319919A1 (en)	2011-05-11
EP2327766A1 (en)	2011-06-01
CA2445046C (en)	2009-11-24
AU2006252258B2 (en)	2010-07-22
WO2003000840A2 (en)	2003-01-03
DK2327767T3 (en)	2015-07-27

Publication	Publication Date	Title
EP1578910A4 (en)	2008-06-04	Nitrilases
DE50202400D1 (en)	2005-04-07	Baw-resonator
DE60209787D1 (en)	2006-05-04	Flächiges implantat
DE60213216D1 (en)	2006-08-31	Metalloproteinaseinhibitoren
DE50201180D1 (en)	2004-11-04	Organopolysiloxan/polyharnstoff/polyurethan-blockcopolymere
DE50209614D1 (en)	2007-04-12	2-heteroarylcarbonsäureamide
DE50211022D1 (en)	2007-11-15	Heteroarylcarbonsäureamide
DE60214551D1 (en)	2006-10-19	Modulares airbagaufblassystem
DE60210819D1 (en)	2006-05-24	Pyrazolopyridazinderivate
DE60141364D1 (en)	2010-04-01	Polyphenylensulfidharzzusammensetzung
DE60141362D1 (en)	2010-04-01	Ösophagus-stoma-knopf
DE50202633D1 (en)	2005-05-04	Ophthalmoskop
DE60223825D1 (en)	2008-01-10	Ethynylierungsverfahren
DE60107296D1 (en)	2004-12-23	Kabelverstärkerverbindungsanordnung
DE60204140D1 (en)	2005-06-16	5-ethyl-imidazotriazinone
DE60216319D1 (en)	2007-01-04	Heteroaryl-substituierte aminocyclohexan-derivate
DE50206483D1 (en)	2006-05-24	Displaymodul
DE50203686D1 (en)	2005-08-25	Substituierte c-furan-2-yl-methylamin- und c-thiophen-2-yl-methylamin-derivate
GB0102319D0 (en)	2001-03-14	Light-diffuser
DE50201028D1 (en)	2004-10-21	Diarylgelbpigmentpraeparationen
DE50214962D1 (en)	2011-04-28	Heterocyclylarylsulfonamide
DE60206072D1 (en)	2005-10-13	Aroylpyridinone
AU2002313943A8 (en)	2008-01-03	Electromobile
GB0106567D0 (en)	2001-05-09	Mutuagenesis Technique
AU2001100134A4 (en)	2001-08-02	Enviro-trap

Legal Events

Date	Code	Title	Description
2005-08-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2005-09-28	17P	Request for examination filed	Effective date: 20031103
2005-09-28	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2005-09-28	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2007-09-05	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: VERENIUM CORPORATION
2007-11-23	PUAK	Availability of information related to the publication of the international search report	Free format text: ORIGINAL CODE: 0009015
2008-01-16	RIC1	Information provided on ipc code assigned before grant	Ipc: C07K 1/00 20060101ALI20071213BHEP Ipc: C12P 7/62 20060101ALI20071213BHEP Ipc: C12P 7/00 20060101ALI20071213BHEP Ipc: C12P 1/00 20060101ALI20071213BHEP Ipc: C07H 21/02 20060101ALI20071213BHEP Ipc: C12N 15/00 20060101ALI20071213BHEP Ipc: C12N 1/20 20060101ALI20071213BHEP Ipc: C12N 9/78 20060101ALI20071213BHEP Ipc: C12N 9/00 20060101AFI20071213BHEP
2008-06-04	A4	Supplementary search report drawn up and despatched	Effective date: 20080508
2008-12-10	17Q	First examination report despatched	Effective date: 20081111
2009-10-09	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2009-11-11	18D	Application deemed to be withdrawn	Effective date: 20090526