EE9800315A - Meetod südamepuudulikkuse käitlemiseks endoteliini antagonistide abil - Google Patents

Meetod südamepuudulikkuse käitlemiseks endoteliini antagonistide abil

Info

Publication number: EE9800315A
Authority: EE; Estonia
Prior art keywords: heart failure; treating heart; endothelin antagonists; blooded animal; warm blooded
Prior art date: 1996-04-04

Application number

EE9800315A

Other languages

English (en)

Estonian (et)

Inventor

J. Lynch Joseph Jr.

Shen You-Tang

Original Assignee

Banyu Pharmaceutical Co., Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-03-19

Publication date

1999-06-15

1997-03-19 Application filed by Banyu Pharmaceutical Co., Ltd. filed Critical Banyu Pharmaceutical Co., Ltd.

1999-06-15 Publication of EE9800315A publication Critical patent/EE9800315A/xx

Links

206010019280 Heart failures Diseases 0.000 title abstract 2
102000002045 Endothelin Human genes 0.000 title 1
108050009340 Endothelin Proteins 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 title 1
208000009982 Ventricular Dysfunction Diseases 0.000 abstract 1
239000002308 endothelin receptor antagonist Substances 0.000 abstract 1
230000006815 ventricular dysfunction Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Materials For Photolithography (AREA)
Photosensitive Polymer And Photoresist Processing (AREA)

EE9800315A 1996-04-04 1997-03-19 Meetod südamepuudulikkuse käitlemiseks endoteliini antagonistide abil EE9800315A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1488296P	1996-04-04	1996-04-04
PCT/US1997/003737 WO1997037665A1 (en)	1996-04-04	1997-03-19	Method of treating heart failure with endothelin antagonists

Publications (1)

Publication Number	Publication Date
EE9800315A true EE9800315A (et)	1999-06-15

Family

ID=21768326

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800315A EE9800315A (et)	1996-04-04	1997-03-19	Meetod südamepuudulikkuse käitlemiseks endoteliini antagonistide abil

Country Status (25)

Country	Link
US (3)	US5834483A (pt)
EP (1)	EP0906108B1 (pt)
JP (2)	JP3345891B2 (pt)
KR (1)	KR20000005178A (pt)
CN (1)	CN1215335A (pt)
AT (1)	ATE297739T1 (pt)
AU (1)	AU723351B2 (pt)
BG (1)	BG102716A (pt)
BR (1)	BR9708525A (pt)
CA (1)	CA2249330C (pt)
CZ (1)	CZ296098A3 (pt)
DE (1)	DE69733557T2 (pt)
EA (1)	EA003587B1 (pt)
EE (1)	EE9800315A (pt)
ES (1)	ES2241047T3 (pt)
HU (1)	HUP9903893A3 (pt)
IL (1)	IL126175A (pt)
IS (1)	IS4847A (pt)
NO (1)	NO984564L (pt)
NZ (1)	NZ331789A (pt)
PL (1)	PL329077A1 (pt)
SK (1)	SK130098A3 (pt)
TR (1)	TR199801988T2 (pt)
UA (1)	UA50761C2 (pt)
WO (1)	WO1997037665A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL329077A1 (en) *	1996-04-04	1999-03-15	Banyu Pharma Co Ltd	Method of treating cardiac insufficiency by means of endotelin antagonists
AU711936B2 (en) *	1996-08-09	1999-10-28	Banyu Pharmaceutical Co., Ltd.	Stereoselective deoxygenation reaction
AU742423B2 (en)	1998-01-21	2002-01-03	Msd K.K.	Substituted 5-(2,2-difluoro-1,3-benzodioxol-5-yl) cyclopentenopyridine derivative
US8168616B1 (en)	2000-11-17	2012-05-01	Novartis Ag	Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
US20060089503A1 (en) *	2002-12-27	2006-04-27	Kaneka Corporation	Processes for producing optically active 2-thiomethyl-3-phenylpropionic acid derivative and for producing intermediate therefor
WO2005049022A2 (en)	2003-11-17	2005-06-02	Novartis Ag	Use of dipeptidyl peptidase iv inhibitors
GB0327839D0 (en)	2003-12-01	2003-12-31	Novartis Ag	Organic compounds
WO2005089731A2 (en)	2004-03-17	2005-09-29	Novartis Ag	Use of renin inhibitors in therapy
EP1894582A1 (en)	2005-06-24	2008-03-05	Tokyo Medical and Dental University	Method for control of drug elution rate and composition for coating of drug-eluting stent
AR080683A1 (es)	2010-03-16	2012-05-02	Novartis Ag	Composiciones farmaceuticas de aliskiren y metodos de administracion

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4971959A (en) *	1987-04-14	1990-11-20	Warner-Lambert Company	Trisubstituted phenyl analogs having activity for congestive heart failure
GB9007762D0 (en) *	1990-04-05	1990-06-06	Beecham Group Plc	Novel compounds
US5565485A (en) *	1993-03-19	1996-10-15	Merck & Co., Inc.	Biphenyl compounds useful or endothelin antagonists
HU9503067D0 (en)	1993-04-27	1995-12-28	Smithkline Beecham Corp	Endotheline receptor antagonists
US5571813A (en) *	1993-06-10	1996-11-05	Beiersdorf-Lilly Gmbh	Fused pyrimidine compounds and their use as pharmaceuticals
US5389620A (en) *	1993-08-18	1995-02-14	Banyu Pharmaceutical Co., Ltd.	Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives
AU675870B2 (en) *	1993-08-18	1997-02-20	Msd K.K.	Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives
US5658943A (en) *	1995-01-05	1997-08-19	Warner-Lambert Company	Phenylalanine derivatives as endothelin antagonists
PL329077A1 (en) *	1996-04-04	1999-03-15	Banyu Pharma Co Ltd	Method of treating cardiac insufficiency by means of endotelin antagonists

1997
- 1997-03-19 PL PL97329077A patent/PL329077A1/xx unknown
- 1997-03-19 IL IL12617597A patent/IL126175A/xx not_active IP Right Cessation
- 1997-03-19 SK SK1300-98A patent/SK130098A3/sk unknown
- 1997-03-19 HU HU9903893A patent/HUP9903893A3/hu unknown
- 1997-03-19 AT AT97914955T patent/ATE297739T1/de not_active IP Right Cessation
- 1997-03-19 BR BR9708525A patent/BR9708525A/pt not_active Application Discontinuation
- 1997-03-19 KR KR1019980707850A patent/KR20000005178A/ko not_active Ceased
- 1997-03-19 TR TR1998/01988T patent/TR199801988T2/xx unknown
- 1997-03-19 CN CN97193645A patent/CN1215335A/zh active Pending
- 1997-03-19 EP EP97914955A patent/EP0906108B1/en not_active Expired - Lifetime
- 1997-03-19 JP JP53619497A patent/JP3345891B2/ja not_active Expired - Fee Related
- 1997-03-19 ES ES97914955T patent/ES2241047T3/es not_active Expired - Lifetime
- 1997-03-19 WO PCT/US1997/003737 patent/WO1997037665A1/en not_active Ceased
- 1997-03-19 NZ NZ331789A patent/NZ331789A/xx unknown
- 1997-03-19 CA CA002249330A patent/CA2249330C/en not_active Expired - Fee Related
- 1997-03-19 AU AU22025/97A patent/AU723351B2/en not_active Ceased
- 1997-03-19 EE EE9800315A patent/EE9800315A/xx unknown
- 1997-03-19 CZ CZ982960A patent/CZ296098A3/cs unknown
- 1997-03-19 DE DE69733557T patent/DE69733557T2/de not_active Expired - Lifetime
- 1997-03-19 EA EA199800889A patent/EA003587B1/ru not_active IP Right Cessation
- 1997-03-19 UA UA98105222A patent/UA50761C2/uk unknown
- 1997-03-26 US US08/824,848 patent/US5834483A/en not_active Expired - Fee Related
1998
- 1998-08-11 US US09/132,514 patent/US6087360A/en not_active Expired - Lifetime
- 1998-08-21 BG BG102716A patent/BG102716A/xx unknown
- 1998-09-15 IS IS4847A patent/IS4847A/is unknown
- 1998-09-30 NO NO984564A patent/NO984564L/no not_active Application Discontinuation
2000
- 2000-02-22 US US09/507,666 patent/US6380195B1/en not_active Expired - Fee Related
2001
- 2001-12-07 JP JP2001374870A patent/JP2002220337A/ja active Pending

Also Published As

Publication number	Publication date
EP0906108A1 (en)	1999-04-07
IS4847A (is)	1998-09-15
CA2249330A1 (en)	1997-10-16
UA50761C2 (uk)	2002-11-15
NO984564D0 (no)	1998-09-30
JP2000510824A (ja)	2000-08-22
EA003587B1 (ru)	2003-06-26
BR9708525A (pt)	1999-08-03
US6380195B1 (en)	2002-04-30
TR199801988T2 (xx)	2000-08-21
SK130098A3 (en)	1999-05-07
BG102716A (en)	1999-09-30
IL126175A (en)	2003-05-29
EP0906108A4 (en)	2000-12-06
US5834483A (en)	1998-11-10
JP3345891B2 (ja)	2002-11-18
NZ331789A (en)	2000-05-26
CZ296098A3 (cs)	1999-06-16
CA2249330C (en)	2005-08-09
DE69733557T2 (de)	2005-11-03
ES2241047T3 (es)	2005-10-16
PL329077A1 (en)	1999-03-15
WO1997037665A1 (en)	1997-10-16
ATE297739T1 (de)	2005-07-15
DE69733557D1 (de)	2005-07-21
EA199800889A1 (ru)	1999-04-29
AU723351B2 (en)	2000-08-24
NO984564L (no)	1998-12-04
CN1215335A (zh)	1999-04-28
IL126175A0 (en)	1999-05-09
US6087360A (en)	2000-07-11
HUP9903893A3 (en)	2001-05-28
KR20000005178A (ko)	2000-01-25
HUP9903893A2 (hu)	2001-04-28
EP0906108B1 (en)	2005-06-15
JP2002220337A (ja)	2002-08-09
AU2202597A (en)	1997-10-29

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IS6105A (is)	2001-10-11	Aðferð til meðferðar á netjuhersli með notkun mótlyfs við integríninu alfa-4
DE69617729D1 (de)	2002-01-17	Verwendung von antimineralcorticoidverbindungen gegen das drogenentzugssyndrom
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PT1039900E (pt)	2004-09-30	Agentes terapeuticos
EA200100716A1 (ru)	2002-06-27	Способ профилактики рака молочной железы
WO2000048446A3 (en)	2001-02-08	Use of antagonists of pg-e for the treatment of neuropathic pain
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ATE242641T1 (de)	2003-06-15	Behandlung von stressinduzierten hautkrankheiten unter verwendung von corticoliberin (crh)- antagonisten und inhibitoren der hautmastzell- degranulation
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