HUP9903893A3 - Method of treating heart failure with cyclopentane fused heterocyclic endothelin antagonists - Google Patents

Method of treating heart failure with cyclopentane fused heterocyclic endothelin antagonists

Info

Publication number: HUP9903893A3
Authority: HU; Hungary
Prior art keywords: heart failure; fused heterocyclic; treating heart; endothelin antagonists; cyclopentane fused
Prior art date: 1996-04-04

Application number

HU9903893A

Other languages

English (en)

Original Assignee

Banyu Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-03-19

Publication date

2001-05-28

1997-03-19 Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd

2001-04-28 Publication of HUP9903893A2 publication Critical patent/HUP9903893A2/hu

2001-05-28 Publication of HUP9903893A3 publication Critical patent/HUP9903893A3/hu

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Materials For Photolithography (AREA)
Photosensitive Polymer And Photoresist Processing (AREA)

HU9903893A 1996-04-04 1997-03-19 Method of treating heart failure with cyclopentane fused heterocyclic endothelin antagonists HUP9903893A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1488296P	1996-04-04	1996-04-04
PCT/US1997/003737 WO1997037665A1 (en)	1996-04-04	1997-03-19	Method of treating heart failure with endothelin antagonists

Publications (2)

Publication Number	Publication Date
HUP9903893A2 HUP9903893A2 (hu)	2001-04-28
HUP9903893A3 true HUP9903893A3 (en)	2001-05-28

Family

ID=21768326

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9903893A HUP9903893A3 (en)	1996-04-04	1997-03-19	Method of treating heart failure with cyclopentane fused heterocyclic endothelin antagonists

Country Status (25)

Country	Link
US (3)	US5834483A (hu)
EP (1)	EP0906108B1 (hu)
JP (2)	JP3345891B2 (hu)
KR (1)	KR20000005178A (hu)
CN (1)	CN1215335A (hu)
AT (1)	ATE297739T1 (hu)
AU (1)	AU723351B2 (hu)
BG (1)	BG102716A (hu)
BR (1)	BR9708525A (hu)
CA (1)	CA2249330C (hu)
CZ (1)	CZ296098A3 (hu)
DE (1)	DE69733557T2 (hu)
EA (1)	EA003587B1 (hu)
EE (1)	EE9800315A (hu)
ES (1)	ES2241047T3 (hu)
HU (1)	HUP9903893A3 (hu)
IL (1)	IL126175A (hu)
IS (1)	IS4847A (hu)
NO (1)	NO984564L (hu)
NZ (1)	NZ331789A (hu)
PL (1)	PL329077A1 (hu)
SK (1)	SK130098A3 (hu)
TR (1)	TR199801988T2 (hu)
UA (1)	UA50761C2 (hu)
WO (1)	WO1997037665A1 (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2249330C (en) *	1996-04-04	2005-08-09	Banyu Pharmaceutical Co., Ltd.	Method of treating heart failure with endothelin antagonists
JPH11514676A (ja) *	1996-08-09	1999-12-14	メルクエンドカンパニーインコーポレーテッド	立体選択的脱酸素化反応
JP4432261B2 (ja)	1998-01-21	2010-03-17	萬有製薬株式会社	複素芳香環縮合シクロペンテノピリジン誘導体
US8168616B1 (en)	2000-11-17	2012-05-01	Novartis Ag	Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
JPWO2004060885A1 (ja) *	2002-12-27	2006-05-11	株式会社カネカ	光学活性２−チオメチル−３−フェニルプロピオン酸誘導体およびその合成中間体の製造法
KR20130105741A (ko)	2003-11-17	2013-09-25	노파르티스 아게	디펩티딜 펩티다제 ⅳ 억제제의 용도
GB0327839D0 (en)	2003-12-01	2003-12-31	Novartis Ag	Organic compounds
KR20070006774A (ko)	2004-03-17	2007-01-11	노파르티스 아게	치료에서 레닌 억제제의 용도
JP4967136B2 (ja)	2005-06-24	2012-07-04	国立大学法人東京医科歯科大学	薬剤溶出性ステント
WO2011116115A1 (en)	2010-03-16	2011-09-22	Novartis Ag	Aliskiren composition comprising a medium chain fatty acid, their process of manufacturing

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4971959A (en) *	1987-04-14	1990-11-20	Warner-Lambert Company	Trisubstituted phenyl analogs having activity for congestive heart failure
GB9007762D0 (en) *	1990-04-05	1990-06-06	Beecham Group Plc	Novel compounds
US5565485A (en) *	1993-03-19	1996-10-15	Merck & Co., Inc.	Biphenyl compounds useful or endothelin antagonists
BR9406572A (pt)	1993-04-27	1996-01-30	Smithkline Beecham Corp	Antagonistas receptores do endotelin
US5571813A (en) *	1993-06-10	1996-11-05	Beiersdorf-Lilly Gmbh	Fused pyrimidine compounds and their use as pharmaceuticals
JP2847969B2 (ja) *	1993-08-18	1999-01-20	萬有製薬株式会社	エンドセリン拮抗活性を有する複素芳香環縮合シクロペンテン誘導体
US5389620A (en) *	1993-08-18	1995-02-14	Banyu Pharmaceutical Co., Ltd.	Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives
US5658943A (en) *	1995-01-05	1997-08-19	Warner-Lambert Company	Phenylalanine derivatives as endothelin antagonists
CA2249330C (en) *	1996-04-04	2005-08-09	Banyu Pharmaceutical Co., Ltd.	Method of treating heart failure with endothelin antagonists

1997
- 1997-03-19 CA CA002249330A patent/CA2249330C/en not_active Expired - Fee Related
- 1997-03-19 IL IL12617597A patent/IL126175A/xx not_active IP Right Cessation
- 1997-03-19 NZ NZ331789A patent/NZ331789A/xx unknown
- 1997-03-19 ES ES97914955T patent/ES2241047T3/es not_active Expired - Lifetime
- 1997-03-19 CZ CZ982960A patent/CZ296098A3/cs unknown
- 1997-03-19 CN CN97193645A patent/CN1215335A/zh active Pending
- 1997-03-19 BR BR9708525A patent/BR9708525A/pt not_active Application Discontinuation
- 1997-03-19 KR KR1019980707850A patent/KR20000005178A/ko not_active Ceased
- 1997-03-19 AU AU22025/97A patent/AU723351B2/en not_active Ceased
- 1997-03-19 AT AT97914955T patent/ATE297739T1/de not_active IP Right Cessation
- 1997-03-19 EE EE9800315A patent/EE9800315A/xx unknown
- 1997-03-19 DE DE69733557T patent/DE69733557T2/de not_active Expired - Lifetime
- 1997-03-19 JP JP53619497A patent/JP3345891B2/ja not_active Expired - Fee Related
- 1997-03-19 WO PCT/US1997/003737 patent/WO1997037665A1/en not_active Ceased
- 1997-03-19 PL PL97329077A patent/PL329077A1/xx unknown
- 1997-03-19 UA UA98105222A patent/UA50761C2/uk unknown
- 1997-03-19 HU HU9903893A patent/HUP9903893A3/hu unknown
- 1997-03-19 SK SK1300-98A patent/SK130098A3/sk unknown
- 1997-03-19 EP EP97914955A patent/EP0906108B1/en not_active Expired - Lifetime
- 1997-03-19 TR TR1998/01988T patent/TR199801988T2/xx unknown
- 1997-03-19 EA EA199800889A patent/EA003587B1/ru not_active IP Right Cessation
- 1997-03-26 US US08/824,848 patent/US5834483A/en not_active Expired - Fee Related
1998
- 1998-08-11 US US09/132,514 patent/US6087360A/en not_active Expired - Lifetime
- 1998-08-21 BG BG102716A patent/BG102716A/xx unknown
- 1998-09-15 IS IS4847A patent/IS4847A/is unknown
- 1998-09-30 NO NO984564A patent/NO984564L/no not_active Application Discontinuation
2000
- 2000-02-22 US US09/507,666 patent/US6380195B1/en not_active Expired - Fee Related
2001
- 2001-12-07 JP JP2001374870A patent/JP2002220337A/ja active Pending

Also Published As

Publication number	Publication date
EA003587B1 (ru)	2003-06-26
EP0906108A1 (en)	1999-04-07
EP0906108A4 (en)	2000-12-06
BG102716A (en)	1999-09-30
KR20000005178A (ko)	2000-01-25
CN1215335A (zh)	1999-04-28
JP2000510824A (ja)	2000-08-22
EA199800889A1 (ru)	1999-04-29
AU723351B2 (en)	2000-08-24
TR199801988T2 (xx)	2000-08-21
DE69733557D1 (de)	2005-07-21
BR9708525A (pt)	1999-08-03
DE69733557T2 (de)	2005-11-03
NZ331789A (en)	2000-05-26
PL329077A1 (en)	1999-03-15
JP3345891B2 (ja)	2002-11-18
US5834483A (en)	1998-11-10
EE9800315A (et)	1999-06-15
HUP9903893A2 (hu)	2001-04-28
IL126175A (en)	2003-05-29
JP2002220337A (ja)	2002-08-09
WO1997037665A1 (en)	1997-10-16
US6087360A (en)	2000-07-11
UA50761C2 (uk)	2002-11-15
NO984564L (no)	1998-12-04
ES2241047T3 (es)	2005-10-16
IS4847A (is)	1998-09-15
US6380195B1 (en)	2002-04-30
CA2249330A1 (en)	1997-10-16
CA2249330C (en)	2005-08-09
NO984564D0 (no)	1998-09-30
EP0906108B1 (en)	2005-06-15
AU2202597A (en)	1997-10-29
SK130098A3 (en)	1999-05-07
ATE297739T1 (de)	2005-07-15
CZ296098A3 (cs)	1999-06-16
IL126175A0 (en)	1999-05-09

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