[go: up one dir, main page]

EE9700339A - Allergiate ennetamise ja ravi meetodid - Google Patents

Allergiate ennetamise ja ravi meetodid

Info

Publication number
EE9700339A
EE9700339A EE9700339A EE9700339A EE9700339A EE 9700339 A EE9700339 A EE 9700339A EE 9700339 A EE9700339 A EE 9700339A EE 9700339 A EE9700339 A EE 9700339A EE 9700339 A EE9700339 A EE 9700339A
Authority
EE
Estonia
Prior art keywords
treatment methods
allergy prevention
allergy
prevention
treatment
Prior art date
Application number
EE9700339A
Other languages
English (en)
Other versions
EE03424B1 (et
Inventor
Isolauri Erika
Mets�niitty Leena
Korhonen Hannu
Salminen Seppo
Syv�oja Eeva-Liisa
Original Assignee
Valio Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8543602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE9700339(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Valio Oy filed Critical Valio Oy
Publication of EE9700339A publication Critical patent/EE9700339A/et
Publication of EE03424B1 publication Critical patent/EE03424B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EE9700339A 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod EE03424B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI952926A FI104465B (fi) 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
PCT/FI1996/000350 WO1997000078A1 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies

Publications (2)

Publication Number Publication Date
EE9700339A true EE9700339A (et) 1998-06-15
EE03424B1 EE03424B1 (et) 2001-06-15

Family

ID=8543602

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700339A EE03424B1 (et) 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod

Country Status (26)

Country Link
US (2) US6506380B1 (et)
EP (1) EP0833649B2 (et)
JP (1) JP3983804B2 (et)
KR (1) KR100494741B1 (et)
CN (1) CN1154506C (et)
AR (1) AR003960A1 (et)
AT (1) ATE230606T1 (et)
BG (1) BG63153B1 (et)
BR (1) BR9607827A (et)
CA (1) CA2224320C (et)
CZ (1) CZ291904B6 (et)
DE (1) DE69625690T3 (et)
DK (1) DK0833649T4 (et)
EE (1) EE03424B1 (et)
ES (1) ES2191103T5 (et)
FI (1) FI104465B (et)
IL (1) IL122577A0 (et)
MX (1) MX9710109A (et)
MY (1) MY113912A (et)
NO (1) NO321504B1 (et)
NZ (1) NZ310478A (et)
PL (1) PL185123B1 (et)
RO (1) RO120243B1 (et)
SK (1) SK284245B6 (et)
WO (1) WO1997000078A1 (et)
ZA (1) ZA965088B (et)

Families Citing this family (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
EP0986314B1 (en) * 1997-06-03 2008-09-10 Ganeden Biotech, Inc. Probiotic lactic acid bacterium to treat bacterial infections associated with sids
WO2000042561A2 (en) 1999-01-19 2000-07-20 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
ES2321797T3 (es) 1999-08-05 2009-06-12 Societe Des Produits Nestle S.A. Bifidobacterias que previenen la diarrea causada por bacterias patogenicas.
CA2378426C (en) 1999-08-05 2010-03-23 Societe Des Produits Nestle S.A. Bifidobacteria capable of preventing diarrhea
WO2001057534A2 (en) * 2000-02-04 2001-08-09 Bioseek Compositions and methods for reducing autoimmunity
FI110668B (fi) 2000-06-20 2003-03-14 Aboatech Ab Oy Probioottien käyttö atooppisten sairauksien primaariseen ehkäisyyn
US7498162B2 (en) * 2000-09-25 2009-03-03 Nestec S.A. Lactic acid bacteria capable of reducing an individual's tendency to develop allergic reactions
JP4510376B2 (ja) * 2000-10-06 2010-07-21 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 皮膚の免疫系のバランスを保つためのプロバイオティック乳酸菌の使用
FI109602B (fi) * 2001-01-25 2002-09-13 Valio Oy Probioottiyhdistelmä
EP1228707A1 (en) * 2001-02-01 2002-08-07 Campina Melkunie B.V. Use of alpha-lactalbumin as prebiotic agent
CN1638650A (zh) * 2001-03-09 2005-07-13 雀巢制品公司 改善与年龄有关的生理缺陷并延长寿命的组合物
JP2003137804A (ja) * 2001-10-31 2003-05-14 Morinaga Milk Ind Co Ltd インターロイキン−１８誘導剤
EP1364586A1 (en) * 2002-05-24 2003-11-26 Nestec S.A. Probiotics and oral tolerance
ES2540926T3 (es) 2002-06-04 2015-07-14 Dsm Ip Assets B.V. Hidrolizado de proteínas rico en tripéptidos
ES2311729T5 (es) 2002-06-28 2013-02-14 Biosearch S.A. Cepas probióticas, un procedimiento para la selección de ellas, composiciones de las mismas y su uso
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
US7105336B2 (en) * 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
US20040208863A1 (en) * 2003-01-30 2004-10-21 James Versalovic Anti-inflammatory activity from lactic acid bacteria
WO2004112509A2 (en) * 2003-06-23 2004-12-29 Nestec S.A. Nutritional formula for optimal gut barrier function
KR101225918B1 (ko) 2004-02-25 2013-01-24 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 신규한 바실루스 투링기엔시스 결정 폴리펩티드,폴리뉴클레오티드, 및 이의 조성물
US20050265946A1 (en) * 2004-05-28 2005-12-01 Kao Corporation Elastase inhibitor
US7862808B2 (en) 2004-07-01 2011-01-04 Mead Johnson Nutrition Company Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12
CA2604338A1 (en) 2005-04-13 2006-10-19 Nestec S.A. Infant formula with probiotics
US7303745B2 (en) * 2005-04-15 2007-12-04 Bristol-Myers Squibb Company Method for preventing or treating the development of respiratory allergies
US20060233762A1 (en) * 2005-04-15 2006-10-19 Mcmahon Robert J Method for treating or preventing systemic inflammation in formula-fed infants
WO2007054587A1 (en) * 2005-11-14 2007-05-18 Nestec S.A. Oral tolerance promotion with glycated proteins
MY148872A (en) 2006-02-15 2013-06-14 Nestec Sa Use of bifidobacterium longum for the prevention and treatment of inflammation
RU2448720C2 (ru) 2006-03-07 2012-04-27 Нестек С.А. Синбиотическая смесь
CN101460067B (zh) * 2006-06-15 2012-09-26 雀巢产品技术援助有限公司 诱导对卵蛋白的耐受
ES2381232T3 (es) * 2007-02-28 2012-05-24 Mead Johnson Nutrition Company Procedimiento para el tratamiento o la prevención de la inflamación sistémica
EP1974734A1 (en) † 2007-03-28 2008-10-01 Nestec S.A. Probiotics for reduction of risk of obesity
EP1974735A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Reduction of risk of diarrhoea
EP1974743A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Probiotics to Improve Gut Microbiota
CN101273736B (zh) 2007-03-28 2012-08-08 北京弗蒙特生物技术有限公司 一种在常温下保持高活菌数的发酵乳的制备方法
WO2009029554A2 (en) 2007-08-24 2009-03-05 Codexis, Inc. Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
EP2072052A1 (en) 2007-12-17 2009-06-24 Nestec S.A. Prevention of opportunistic infections in immune-compromised subjects
UA101176C2 (ru) 2008-01-24 2013-03-11 Нестек С.А. Капсула для применения в устройстве для приготовления напитков, которая содержит питательные ингредиенты и способ получения питательной жидкости из капсулы
ES2585407T3 (es) 2008-02-01 2016-10-05 Murdoch Childrens Research Institute Un método para inducir tolerancia a un alérgeno
EP2265135B1 (en) 2008-03-14 2017-12-20 Nestec S.A. Synbiotic mixture
EP2127661A1 (en) 2008-05-27 2009-12-02 Nestec S.A. Probiotics to improve gut microbiotica
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
CN102066561B (zh) 2008-06-13 2013-09-25 科德克希思公司 合成多核苷酸变体的方法
WO2010008828A2 (en) 2008-06-24 2010-01-21 Codexis, Inc. Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds
EP2147678A1 (en) 2008-07-21 2010-01-27 Nestec S.A. Probiotics to increase IgA secretion in infants born by caesarean section
RU2392001C2 (ru) * 2008-08-04 2010-06-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" Способ лечения желтушных форм вирусного гепатита а у детей с пищевой аллергией
EP2329013B1 (en) 2008-08-27 2015-10-28 Codexis, Inc. Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
HUE052297T2 (hu) 2009-01-08 2021-04-28 Codexis Inc Transzamináz polipeptidek
BRPI1013886A2 (pt) 2009-03-17 2016-10-11 Codexis Inc variantes de endoglucanases, polinucleotídeos e usos a elas relacionados
CA2757040C (en) 2009-03-31 2016-02-09 Codexis, Inc. Improved endoglucanases
US8357523B2 (en) 2009-06-16 2013-01-22 Codexis, Inc. Beta-glucosidase variant enzymes and related polynucleotides
SG177331A1 (en) 2009-06-22 2012-02-28 Codexis Inc Ketoreductase-mediated stereoselective route to alpha chloroalcohols
WO2011011630A2 (en) 2009-07-23 2011-01-27 Codexis, Inc. Nitrilase biocatalysts
EP2467032B1 (en) 2009-08-18 2018-02-21 Nestec S.A. A nutritional composition comprising bifidobacterium longum strains and reducing food allergy symptoms, especially in infants and children
PT2467031E (pt) * 2009-08-18 2014-10-30 Nestec Sa Composição nutricional compreendendo estirpes lactococcus e redução de sintomas de alergia, especialmente em bebés e crianças
US9102959B2 (en) 2009-08-19 2015-08-11 Codexis, Inc. Ketoreductase polypeptides for the preparation of phenylephrine
EP2473604B1 (en) 2009-09-04 2017-01-11 Codexis, Inc. Variant cbh2 cellulases and related polynucleotides
EP2295535A1 (en) * 2009-09-11 2011-03-16 Mead Johnson Nutrition Company Probiotic material
DK2478137T3 (da) 2009-09-18 2017-11-27 Codexis Inc Reduceret kodonmutagenese
EP2504431A4 (en) 2009-11-25 2013-10-16 Codexis Inc RECOMBINANT BETA-GLUCOSIDASE VARIANTS OF THERMOASCUS AURIENTIACUS FOR THE PRODUCTION OF FERMENTABLE SUGARS FROM CELLULOSIC BIOMASS
PL2504017T3 (pl) 2009-11-25 2014-06-30 Codexis Inc Rekombinacyjne warianty beta-glukozydazy do wytwarzania rozpuszczalnych cukrów z biomasy celulozowej
AU2010329990B2 (en) 2009-12-08 2015-07-16 Nestec S.A. Infant formula with probiotics and milk fat globule membrane components
WO2011071982A2 (en) 2009-12-08 2011-06-16 Codexis, Inc. Synthesis of prazole compounds
CA2786001A1 (en) 2009-12-31 2011-07-07 Pioneer Hi-Bred International, Inc. Engineering plant resistance to diseases caused by pathogens
HUE026367T2 (en) 2010-05-04 2016-06-28 Codexis Inc Biocatalysts for ezetimibe synthesis
EP2569331A1 (en) 2010-05-10 2013-03-20 Perseid Therapeutics LLC Polypeptide inhibitors of vla4
EP2576804B1 (en) 2010-05-28 2016-12-14 Codexis, Inc. Pentose fermentation by a recombinant microorganism
WO2011159910A2 (en) 2010-06-17 2011-12-22 Codexis, Inc. Biocatalysts and methods for the synthesis of (s)-3-(1-aminoethyl)-phenol
US8574878B2 (en) 2010-06-28 2013-11-05 Behnaz Behrouzian Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
AU2011272878B2 (en) 2010-06-30 2015-04-23 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
CA2808098C (en) 2010-08-16 2020-03-10 Merck Sharp & Dohme Corp. Process for preparing aminocyclohexyl ether compounds
US9493802B2 (en) 2010-08-20 2016-11-15 Codexis, Inc. Use of glycohydrolase 61 protein variants with improved thermostability for processing cellulose
WO2012078800A2 (en) 2010-12-08 2012-06-14 Codexis, Inc. Biocatalysts and methods for the synthesis of armodafinil
EE05750B1 (et) 2011-02-25 2015-06-15 OÜ Tervisliku Piima Biotehnoloogiate Arenduskeskus Isoleeritud mikroorganismi tüvi Lactobacillus gasseri MCC2 DSM 23882 ning selle kasutamine
EP2691517A4 (en) 2011-03-30 2015-04-22 Codexis Inc FERMENTATION OF PENTOSES BY A RECOMBINANT MICROORGANISM
EP2697662B1 (en) 2011-04-13 2018-06-06 Codexis, Inc. Biocatalytic process for preparing eslicarbazepine and analogs thereof
UA111078C2 (uk) * 2011-05-03 2016-03-25 Нестек С.А. Гідролізат білкового субстрату і спосіб його виготовлення
US8778652B2 (en) 2011-06-30 2014-07-15 Codexis, Inc. Pentose fermentation by a recombinant microorganism
EP2748317B1 (en) 2011-08-22 2017-04-19 Codexis, Inc. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity
CN103998461B (zh) 2011-09-08 2018-02-02 科德克希思公司 用于合成取代的内酰胺的生物催化剂和方法
US20130084608A1 (en) 2011-09-30 2013-04-04 Codexis, Inc. Fungal proteases
WO2013052101A1 (en) * 2011-10-03 2013-04-11 Kelly Foods Corporation Probiotic composition for pets and method of providing the same
US20130089638A1 (en) * 2011-10-11 2013-04-11 Mead Johnson Nutrition Company Compositions Comprising Maltotriose And Methods Of Using Same To Inhibit Damage Caused By Dehydration Processes
CN104053771B (zh) 2011-11-18 2016-11-09 科德克希思公司 用于制备羟基取代的氨基甲酸酯的生物催化剂
EP2794871A4 (en) 2011-12-20 2015-12-30 Codexis Inc VARIANTS OF ENDOGLUCANASE-1B (EG1B)
US20130251829A1 (en) * 2012-03-23 2013-09-26 Mead Johnson Nutrition Company Probiotic derived non-viable material for infection prevention and treatment
DK2828385T3 (en) 2012-03-23 2018-03-12 Codexis Inc BIOCATALIZATORS AND METHODS FOR SYNTHETIZING DERIVATIVES AND TRYPTAMIN AND TRYPTAMINE ANALOGS
ES2712682T3 (es) 2012-05-08 2019-05-14 Codexis Inc Biocatalizadores y métodos para la hidroxilación de compuestos químicos
US9193957B2 (en) 2012-05-11 2015-11-24 Codexis, Inc. Engineered imine reductases and methods for the reductive animation of ketone and amine compounds
DK2859099T3 (da) 2012-06-11 2019-07-29 Codexis Inc Svampe-beta-xylosidase-varianter
WO2014081605A1 (en) 2012-11-20 2014-05-30 Codexis, Inc. Pentose fermentation by a recombinant microorganism
US9738915B2 (en) 2012-12-07 2017-08-22 Merck Sharp & Dohme Corp. Biocatalytic transamination process
CN105008528A (zh) 2012-12-21 2015-10-28 科德克希思公司 用于合成手性胺的工程化的生物催化剂和方法
WO2014113521A1 (en) 2013-01-18 2014-07-24 Codexis, Inc. Engineered biocatalysts useful for carbapenem synthesis
JP6436541B2 (ja) 2013-02-28 2018-12-12 コデクシス， インコーポレイテッド 工業的生体触媒作用のための操作されたトランスアミナーゼポリペプチド
CN103355405A (zh) * 2013-04-07 2013-10-23 苏州旭优食品科技有限公司 一种低过敏性含乳制品的加工工艺
KR102218930B1 (ko) 2013-04-18 2021-02-23 코덱시스, 인코포레이티드 조작된 페닐알라닌 암모니아 리아제 폴리펩티드
CA2929664C (en) 2013-11-13 2023-01-24 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
HUE056444T2 (hu) 2014-04-16 2022-02-28 Codexis Inc Génmódosított tirozin-ammónia-liáz
US9708587B2 (en) 2014-07-09 2017-07-18 Codexis, Inc. P450-BM3 variants with improved activity
US10370648B2 (en) 2014-11-25 2019-08-06 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
KR102702200B1 (ko) 2014-12-22 2024-09-02 코덱시스, 인코포레이티드 인간 알파-갈락토시다제 변이체
WO2016130412A1 (en) 2015-02-10 2016-08-18 Codexis, Inc. Ketoreductase polypeptides for the synthesis of chiral compounds
SG11201708356PA (en) 2015-05-07 2017-11-29 Codexis Inc Penicillin-g acylases
WO2017007547A1 (en) 2015-07-07 2017-01-12 Codexis, Inc. Novel p450-bm3 variants with improved activity
US10724025B2 (en) 2016-05-05 2020-07-28 Codexis, Inc. Penicillin-G acylases
US10184117B2 (en) 2016-06-09 2019-01-22 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
EP3471744A4 (en) 2016-06-15 2020-07-29 Codexis, Inc. REVISED BETA-GLUCOSIDASES AND GLUCOSYLATION PROCESSES
EP4223766A3 (en) 2016-08-26 2023-10-18 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
CA3048475A1 (en) 2017-01-05 2018-07-12 Codexis, Inc. Penicillin-g acylases
CN110914445B (zh) 2017-02-03 2024-08-27 泰莱解决方案美国有限责任公司 工程化糖基转移酶和甜菊醇糖苷葡糖基化方法
EP3579867A4 (en) 2017-02-13 2021-03-10 Codexis, Inc. MANIPULATED PHENYLALANINE AMMONIA LYASE POLYPEPTIDES
ES2926255T3 (es) 2017-04-24 2022-10-24 Tesaro Inc Métodos de fabricación de niraparib
WO2018200214A2 (en) 2017-04-27 2018-11-01 Codexis, Inc. Ketoreductase polypeptides and polynucleotides
MX2019013289A (es) 2017-05-08 2020-01-15 Codexis Inc Variantes de ligasa modificadas geneticamente.
WO2018231462A1 (en) 2017-06-14 2018-12-20 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
WO2019005337A1 (en) 2017-06-27 2019-01-03 Codexis, Inc. PENICILLIN G ACYLASES
WO2019005540A1 (en) 2017-06-30 2019-01-03 Codexis, Inc. T7 POLYMERASE RNA VARIANTS
WO2019005539A1 (en) 2017-06-30 2019-01-03 Codexis, Inc. T7 POLYMERASE RNA VARIANTS
CA3080512A1 (en) 2017-11-07 2019-05-16 Codexis, Inc. Transglutaminase variants
CA3085261A1 (en) 2017-12-13 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Carboxyesterase biocatalysts
WO2019118557A1 (en) 2017-12-13 2019-06-20 Codexis, Inc. Carboxyesterase polypeptides for amide coupling
US10900055B2 (en) 2018-06-12 2021-01-26 Codexis, Inc. Engineered tyrosine ammonia lyase
MX2021000326A (es) 2018-07-09 2021-03-25 Codexis Inc Desoxirribosa-fosfato aldolasas modificadas geneticamente.
AU2019300837B2 (en) 2018-07-09 2025-05-22 Codexis, Inc. Engineered galactose oxidase variant enzymes
KR20210031929A (ko) 2018-07-09 2021-03-23 코덱시스, 인코포레이티드 조작된 판토테네이트 키나제 변이체 효소
SG11202012109UA (en) 2018-07-09 2021-01-28 Codexis Inc Engineered phosphopentomutase variant enzymes
CA3103718A1 (en) 2018-07-09 2020-01-16 Codexis, Inc. Engineered purine nucleoside phosphorylase variant enzymes
US11198861B2 (en) 2018-07-12 2021-12-14 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
JP7584401B2 (ja) 2018-07-30 2024-11-15 テイト アンド ライル ソリューションズ ユー・エス・エー エル・エル・シー 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
CN113316635A (zh) 2018-10-29 2021-08-27 科德克希思公司 工程化dna聚合酶变体
WO2020123286A1 (en) 2018-12-14 2020-06-18 Codexis, Inc. Engineered tyrosine ammonia lyase
CA3123598A1 (en) 2018-12-20 2020-06-25 Codexis, Inc. Human alpha-galactosidase variants
EP3911738A4 (en) 2019-01-15 2023-03-01 Codexis, Inc. Engineered transaminase polypeptides
CA3137734A1 (en) 2019-05-01 2020-11-05 Codexis, Inc. Engineered glucose dehydrogenases and methods for the reductive amination of ketone and amine compounds
EP3963057A4 (en) 2019-05-01 2023-06-14 Codexis, Inc. MANIPULATED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
SG11202113108UA (en) 2019-07-02 2021-12-30 Codexis Inc Engineered acetate kinase variant enzymes
CN114072165A (zh) 2019-07-02 2022-02-18 科德克希思公司 工程化蔗糖磷酸化酶变体酶
WO2021013862A1 (en) 2019-07-23 2021-01-28 Frieslandcampina Nederland B.V. Nutritional composition comprising milk fat and immunoglobulin
JP7699107B2 (ja) 2019-08-30 2025-06-26 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 操作されたリパーゼ改変体
WO2021050348A1 (en) 2019-09-12 2021-03-18 Codexis, Inc. Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine
CN114746745B (zh) 2019-10-02 2025-06-17 美国雅培糖尿病护理公司 通过蛋白质开关检测分析物
US12344865B2 (en) 2019-11-26 2025-07-01 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
BR112022011760A2 (pt) 2019-12-20 2022-08-30 Codexis Inc Fragmento de alfa glicosidase ácida recombinante e/ou de alfa glicosidase ácida recombinante biologicamente ativa, alfa glicosidase ácida recombinante, composição, sequência polinucleotídica recombinante, vetor de expressão, vetor de expressão pdh, célula hospedeira, método para produzir uma variante de alfa glicosidase ácida recombinante, variante de alfa glicosidase ácida recombinante, composição farmacêutica para o tratamento da doença de pompe, composição farmacêutica, método para tratar e/ou prevenir os sintomas da doença de pompe em um indivíduo, e, uso das composições
CA3168922A1 (en) 2020-02-04 2021-08-12 Codexis, Inc. Engineered leucine decarboxylases
EP4133064A4 (en) 2020-04-10 2024-07-24 Codexis, Inc. Engineered transaminase polypeptides
CN116897205A (zh) 2020-08-28 2023-10-17 科德克希思公司 工程化淀粉酶变体
WO2022047262A1 (en) 2020-08-28 2022-03-03 Codexis, Inc. Engineered protease variants
WO2022125960A1 (en) 2020-12-11 2022-06-16 Willow Biosciences, Inc. Recombinant acyl activating enzyme (aae) genes for enhanced biosynthesis of cannabinoids and cannabinoid precursors
US11898174B2 (en) 2020-12-18 2024-02-13 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
IL305922A (en) 2021-04-02 2023-11-01 Codexis Inc Transgenic enzymes of variant guanylate kinase
WO2022212824A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered adenylate kinase variant enzymes
WO2022212832A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered cyclic gmp-amp synthase (cgas) variant enzymes
CA3215105A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered acetate kinase variant enzymes
CA3220735A1 (en) 2021-05-21 2022-11-24 Codexis, Inc. Engineered methionine gamma lyase variants
CA3227215A1 (en) 2021-07-30 2023-02-02 Trish Choudhary Recombinant prenyltransferase polypeptides engineered for enhanced biosynthesis of cannabinoids
WO2023023621A1 (en) 2021-08-19 2023-02-23 Willow Biosciences, Inc. Recombinant olivetolic acid cyclase polypeptides engineered for enhanced biosynthesis of cannabinoids
CN118103501A (zh) 2021-10-15 2024-05-28 科德克希思公司 工程化dna聚合酶变体
WO2023069921A1 (en) 2021-10-19 2023-04-27 Epimeron Usa, Inc. Recombinant thca synthase polypeptides engineered for enhanced biosynthesis of cannabinoids
CA3236731A1 (en) 2021-11-01 2023-05-04 Jonathan Benjamin ASFAHA Engineered leucine decarboxylases
US20250207108A1 (en) 2022-03-31 2025-06-26 Qingdao Kingagroot Chemical Compound Co., Ltd. Monoamine oxidase and application thereof
WO2024040020A1 (en) 2022-08-15 2024-02-22 Absci Corporation Quantitative affinity activity specific cell enrichment
WO2024150146A1 (en) 2023-01-12 2024-07-18 Novartis Ag Engineered ketoreductase polypeptides
WO2025061911A1 (en) 2023-09-22 2025-03-27 Glaxosmithkline Intellectual Property Development Limited Methods of producing nucleotide triphosphates (ntps)
WO2025144700A1 (en) 2023-12-27 2025-07-03 Absci Corporation Nanobody library screening using bacterial surface display
WO2025235589A1 (en) 2024-05-08 2025-11-13 Codexis, Inc. Dna polymerase variants
WO2025242702A1 (en) 2024-05-23 2025-11-27 Glaxosmithkline Intellectual Property Development Limited Enzymatic process for producing n-acetyl galactosamine clusters

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886288A (en) * 1970-06-15 1975-05-27 Swift & Co Cheese manufacture using highly active proteolytic enzymes
JPS5279086A (en) 1975-12-25 1977-07-02 Nippon Soda Co Ltd Preparation of antibiotic tunicamycin
JPS5279083A (en) * 1975-12-26 1977-07-02 Morinaga Milk Industry Co Ltd Production of protein decomposed substance not having bitterness and antigen property
JPS6041751B2 (ja) 1976-06-22 1985-09-18 ジエコ−株式会社 デジタル電子時計
JPS548785A (en) 1977-06-21 1979-01-23 Kikkoman Corp Preparation of protein hydrolyzate
US4839281A (en) † 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
DK589785A (da) * 1985-12-18 1987-06-19 Samuelsson Ernst Gunnar Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet
EP0322589B1 (fr) † 1987-12-23 1993-01-20 Societe Des Produits Nestle S.A. Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques
DD281540A5 (de) 1988-08-08 1990-08-15 Berlin Chemie Veb Verfahren zur herstellung von nutritiva
ES2063882T5 (es) † 1989-10-02 2001-12-01 Novartis Nutrition Ag Hidrolizados de proteinas.
JP3071877B2 (ja) † 1991-06-27 2000-07-31 財団法人糧食研究会 経口寛容誘導能を有する低アレルゲン性酵素分解ペプチド組成物
US5952034A (en) * 1991-10-12 1999-09-14 The Regents Of The University Of California Increasing the digestibility of food proteins by thioredoxin reduction
ES2111625T3 (es) * 1992-07-06 1998-03-16 Nestle Sa Agente antigastritis.
FI94089C (fi) 1992-12-10 1995-07-25 Valio Oy Menetelmä allergiaa aiheuttavien yhdisteiden poistamiseksi proteiinipitoisista koostumuksista
RU2031586C1 (ru) 1993-02-05 1995-03-27 Тамара Георгиевна Извекова Биологически активный кисломолочный продукт "ацидолакт-наринэ" и способ его получения
GB9312369D0 (en) * 1993-06-16 1993-07-28 Sandoz Nutrition Ltd Organic compounds
WO1995014485A1 (en) 1993-11-23 1995-06-01 Kabushiki Kaisha Wado Doctors Group Intestinal flora improver composition, and apparatus and system for producing the same
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö

Also Published As

Publication number Publication date
BG102144A (en) 1998-12-30
JP3983804B2 (ja) 2007-09-26
US7172756B2 (en) 2007-02-06
ATE230606T1 (de) 2003-01-15
SK284245B6 (sk) 2004-12-01
DK0833649T3 (da) 2003-04-07
CA2224320C (en) 2012-03-20
DE69625690D1 (de) 2003-02-13
ES2191103T5 (es) 2009-11-03
US20030113340A1 (en) 2003-06-19
NZ310478A (en) 2000-01-28
DE69625690T2 (de) 2003-11-06
EE03424B1 (et) 2001-06-15
EP0833649A1 (en) 1998-04-08
AR003960A1 (es) 1998-09-30
NO975832D0 (no) 1997-12-11
KR19990022914A (ko) 1999-03-25
DK0833649T4 (da) 2009-07-20
CN1154506C (zh) 2004-06-23
AU6127896A (en) 1997-01-15
AU710126B2 (en) 1999-09-16
FI952926A0 (fi) 1995-06-14
US6506380B1 (en) 2003-01-14
PL185123B1 (pl) 2003-02-28
JPH11510791A (ja) 1999-09-21
CZ291904B6 (cs) 2003-06-18
NO975832L (no) 1997-12-11
NO321504B1 (no) 2006-05-15
MX9710109A (es) 1998-10-31
CN1187772A (zh) 1998-07-15
ZA965088B (en) 1997-01-22
DE69625690T3 (de) 2009-12-24
BR9607827A (pt) 1999-11-30
PL324010A1 (en) 1998-04-27
SK171597A3 (en) 1998-11-04
FI952926L (fi) 1996-12-15
FI104465B (fi) 2000-02-15
BG63153B1 (bg) 2001-05-31
IL122577A0 (en) 1998-06-15
HK1010081A1 (en) 1999-06-11
WO1997000078A1 (en) 1997-01-03
MY113912A (en) 2002-06-29
EP0833649B2 (en) 2009-06-03
KR100494741B1 (ko) 2005-09-30
ES2191103T3 (es) 2003-09-01
CA2224320A1 (en) 1997-01-03
CZ399797A3 (cs) 1998-06-17
EP0833649B1 (en) 2003-01-08
RO120243B1 (ro) 2005-11-30

Similar Documents

Publication Publication Date Title
EE9700339A (et) Allergiate ennetamise ja ravi meetodid
FI970990A7 (fi) Syövän toteaminen ja hoito
EE200000379A (et) Amüloidogeense haiguse profülaktika ja ravi
FI955133A7 (fi) Jäteveden käsittelyprosessi ja laite
DE69602965D1 (de) Betriebsvorrichtung und methode
KR960008976A (ko) 처리장치 및 처리방법
FI972922L (fi) Tarkkaamattomuuden ja yliaktiivisuuden hoito
DE69627188D1 (de) Brille und brillenfassung
FI973163A7 (fi) Pidätyskyvyttömyyden hoitaminen käyttämällä (S)-oksibutyniiniä ja (S)- desetyylioksibutyniiniä
DE69636133D1 (de) Zeicheneingabevorrichtung und Methode
FI931085A7 (fi) Kasvainten vastaisia koostumuksia ja hoitomenetelmiä
NO955356D0 (no) Behandling av hypotalamisk amenorre
NO971900D0 (no) Blandinger og behandling av multippel sklerose
DE69736267D1 (de) Plasmabehandlungsvorrichtung und -verfahren
DE69515626D1 (de) Plasmabehandlungsverfahren und -vorrichtung
FI951060A7 (fi) Formulaatioita ja hoitomenetelmiä
EE9600094A (et) Heitvee puhastusmeetod ja -seade
NO983512D0 (no) Midler for behandling og forhindring av AIDS
PT932400E (pt) Derivados de anticonvulsionantes uteis no tratamento da dor neuropatica
DE69620243D1 (de) Haupt- und nebenstromfilter
DE69616858D1 (de) Kodierungsgerät und Methode
DE69602704D1 (de) Zyklotron und Regelverfahren dazu
FI954213A7 (fi) Kasvainten vastaisia koostumuksia ja hoitomenetelmiä
DE69625881D1 (de) Filter und Filterelement
KR960038005U (ko) 살균 및 조명 겸용등기구

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20091231

KB4A Valid patent at the end of a year

Effective date: 20101231