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EE03424B1 - Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod - Google Patents

Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod

Info

Publication number
EE03424B1
EE03424B1 EE9700339A EE9700339A EE03424B1 EE 03424 B1 EE03424 B1 EE 03424B1 EE 9700339 A EE9700339 A EE 9700339A EE 9700339 A EE9700339 A EE 9700339A EE 03424 B1 EE03424 B1 EE 03424B1
Authority
EE
Estonia
Prior art keywords
preparation
protein hydrolyzate
allergy protein
formulation
hydrolyzate formulation
Prior art date
Application number
EE9700339A
Other languages
English (en)
Other versions
EE9700339A (et
Inventor
Isolauri Erika
Mets�niitty Leena
Korhonen Hannu
Salminen Seppo
Syv�oja Eeva-Liisa
Original Assignee
Valio Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8543602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03424(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Valio Oy filed Critical Valio Oy
Publication of EE9700339A publication Critical patent/EE9700339A/et
Publication of EE03424B1 publication Critical patent/EE03424B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EE9700339A 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod EE03424B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI952926A FI104465B (fi) 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
PCT/FI1996/000350 WO1997000078A1 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies

Publications (2)

Publication Number Publication Date
EE9700339A EE9700339A (et) 1998-06-15
EE03424B1 true EE03424B1 (et) 2001-06-15

Family

ID=8543602

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700339A EE03424B1 (et) 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod

Country Status (26)

Country Link
US (2) US6506380B1 (et)
EP (1) EP0833649B2 (et)
JP (1) JP3983804B2 (et)
KR (1) KR100494741B1 (et)
CN (1) CN1154506C (et)
AR (1) AR003960A1 (et)
AT (1) ATE230606T1 (et)
BG (1) BG63153B1 (et)
BR (1) BR9607827A (et)
CA (1) CA2224320C (et)
CZ (1) CZ291904B6 (et)
DE (1) DE69625690T3 (et)
DK (1) DK0833649T4 (et)
EE (1) EE03424B1 (et)
ES (1) ES2191103T5 (et)
FI (1) FI104465B (et)
IL (1) IL122577A0 (et)
MX (1) MX9710109A (et)
MY (1) MY113912A (et)
NO (1) NO321504B1 (et)
NZ (1) NZ310478A (et)
PL (1) PL185123B1 (et)
RO (1) RO120243B1 (et)
SK (1) SK284245B6 (et)
WO (1) WO1997000078A1 (et)
ZA (1) ZA965088B (et)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012126481A1 (en) 2011-02-25 2012-09-27 OÜ Tervisliku Piima Biotehnoloogiate Arenduskeskus Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use

Families Citing this family (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
DE69839993D1 (de) * 1997-06-03 2008-10-23 Ganeden Biotech Inc Probiotisches milchsäurebakterium zur behandlung bakterieller infektionen in zusammenhang mit sids
JP2002534965A (ja) 1999-01-19 2002-10-22 マキシジェン， インコーポレイテッド 所望の特徴を有する文字ストリング、ポリヌクレオチドおよびポリペプチドを作製するための方法
US6998119B1 (en) 1999-08-05 2006-02-14 Nestec S.A. Feed composition containing Bifidobacterium CNCM 1-2168 capable of preventing diarrhea
HK1046929A1 (zh) 1999-08-05 2003-01-30 雀巢制品公司 预防病原性细菌引起的腹泻的双歧杆菌
AU2001234784A1 (en) * 2000-02-04 2001-08-14 Bioseek Compositions and methods for reducing autoimmunity
FI110668B (fi) 2000-06-20 2003-03-14 Aboatech Ab Oy Probioottien käyttö atooppisten sairauksien primaariseen ehkäisyyn
MXPA03001673A (es) 2000-09-25 2003-06-09 Nestle Sa Bacteria de acido lactico capaz de reducir una tendencia individual a desarrollar reacciones alergicas.
JP4510376B2 (ja) * 2000-10-06 2010-07-21 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 皮膚の免疫系のバランスを保つためのプロバイオティック乳酸菌の使用
FI109602B (fi) * 2001-01-25 2002-09-13 Valio Oy Probioottiyhdistelmä
EP1228707A1 (en) * 2001-02-01 2002-08-07 Campina Melkunie B.V. Use of alpha-lactalbumin as prebiotic agent
EP1372412A2 (en) * 2001-03-09 2004-01-02 Societe Des Produits Nestle S.A. Composition improving age-related physiological deficits and increasing longevity
JP2003137804A (ja) * 2001-10-31 2003-05-14 Morinaga Milk Ind Co Ltd インターロイキン−１８誘導剤
EP1364586A1 (en) * 2002-05-24 2003-11-26 Nestec S.A. Probiotics and oral tolerance
EP1509609B1 (en) 2002-06-04 2015-04-22 DSM IP Assets B.V. Protein hydrolysate rich in tripeptides
SI1565547T2 (sl) 2002-06-28 2013-02-28 Biosearch S.A. Probiotiäśni sevi, postopek za izbiranje le-teh, njihovi sestavki in njihova uporaba
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
US7105336B2 (en) * 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
US20040208863A1 (en) * 2003-01-30 2004-10-21 James Versalovic Anti-inflammatory activity from lactic acid bacteria
CA2530437C (en) * 2003-06-23 2011-11-15 Nestec S.A. Nutritional formula for optimal gut barrier function
EP1718751B1 (en) 2004-02-25 2013-05-01 Pioneer-Hi-Bred International, Inc. Novel bacillus thuringiensis crystal polypeptides, polynucleotides, and compositions thereof
US20050265946A1 (en) * 2004-05-28 2005-12-01 Kao Corporation Elastase inhibitor
US7862808B2 (en) * 2004-07-01 2011-01-04 Mead Johnson Nutrition Company Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12
EP1926395A1 (en) 2005-04-13 2008-06-04 Nestec S.A. Infant formula with probiotics
US7303745B2 (en) * 2005-04-15 2007-12-04 Bristol-Myers Squibb Company Method for preventing or treating the development of respiratory allergies
US20060233762A1 (en) * 2005-04-15 2006-10-19 Mcmahon Robert J Method for treating or preventing systemic inflammation in formula-fed infants
JP2009515929A (ja) * 2005-11-14 2009-04-16 ネステク ソシエテ アノニム 糖化タンパク質を用いた経口免疫寛容促進
RU2445362C2 (ru) 2006-02-15 2012-03-20 Нестек С.А. Применение bifidobacterium longum в производстве лекарственного средства или терапевтической питательной композиции для лечения воспалительного заболевания кишечника у млекопитающего и для ослабления воспаления кишечника, связанного с пищевыми аллергенами, у млекопитающего
AU2007222598B2 (en) 2006-03-07 2013-01-10 Société des Produits Nestlé S.A. Synbiotic mixture
WO2007144397A1 (en) * 2006-06-15 2007-12-21 Nestec S.A. Induction of tolerance to egg proteins
MX2009008875A (es) * 2007-02-28 2009-08-28 Mead Johnson Nutrition Co Producto que contiene probiotico inactivado para niños o infantes.
EP1974735A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Reduction of risk of diarrhoea
EP1974743A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Probiotics to Improve Gut Microbiota
EP1974734A1 (en) † 2007-03-28 2008-10-01 Nestec S.A. Probiotics for reduction of risk of obesity
CN101273736B (zh) * 2007-03-28 2012-08-08 北京弗蒙特生物技术有限公司 一种在常温下保持高活菌数的发酵乳的制备方法
JP2010536385A (ja) 2007-08-24 2010-12-02 コデクシス， インコーポレイテッド （ｒ）−３−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド
EP2072052A1 (en) 2007-12-17 2009-06-24 Nestec S.A. Prevention of opportunistic infections in immune-compromised subjects
WO2009092628A1 (en) 2008-01-24 2009-07-30 Nestec S.A. Capsule containing nutritional ingredients and method of delivery of a nutritional liquid from the capsule
US9402896B2 (en) 2008-02-01 2016-08-02 Murdoch Childrens Research Institute Method of inducing tolerance to an allergen
CN102006788A (zh) 2008-03-14 2011-04-06 雀巢产品技术援助有限公司 合益素混合物
EP2127661A1 (en) 2008-05-27 2009-12-02 Nestec S.A. Probiotics to improve gut microbiotica
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
EP3023494B1 (en) 2008-06-13 2018-11-28 Codexis, Inc. Method of synthesizing polynucleotide variants
EP2307419B1 (en) 2008-06-24 2013-11-06 Codexis, Inc. Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds
EP2147678A1 (en) 2008-07-21 2010-01-27 Nestec S.A. Probiotics to increase IgA secretion in infants born by caesarean section
RU2392001C2 (ru) * 2008-08-04 2010-06-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" Способ лечения желтушных форм вирусного гепатита а у детей с пищевой аллергией
EP2329013B1 (en) 2008-08-27 2015-10-28 Codexis, Inc. Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
WO2010081053A2 (en) 2009-01-08 2010-07-15 Codexis, Inc. Transaminase polypeptides
WO2010107644A2 (en) 2009-03-17 2010-09-23 Codexis, Inc. Variant endoglucanases and related polynucleotides
BRPI1010239A2 (pt) 2009-03-31 2016-10-11 Codexis Inc endoglucanases aprimoradas, derivados e seus usos
US8357523B2 (en) 2009-06-16 2013-01-22 Codexis, Inc. Beta-glucosidase variant enzymes and related polynucleotides
DK3409765T3 (da) 2009-06-22 2021-09-27 Codexis Inc Ketoreduktase-medieret stereoselektiv rute til alpha-chloralkoholer
WO2011011630A2 (en) 2009-07-23 2011-01-27 Codexis, Inc. Nitrilase biocatalysts
BR112012003633A2 (pt) * 2009-08-18 2015-09-01 Nestec Sa "composição nutricional que compreende cepas de bifidobacterium longum e reduz os sintomas de alergia alimentar, especialmente em bebês e crianças."
CN102695427B (zh) * 2009-08-18 2016-04-13 雀巢产品技术援助有限公司 包含乳球菌属菌株并且特别是在婴儿和儿童中减少过敏症状的营养组合物
EP2467473B1 (en) 2009-08-19 2016-03-23 Codexis, Inc. Ketoreductase polypeptides for the preparation of phenylephrine
US8785170B2 (en) 2009-09-04 2014-07-22 Codexis, Inc. Variant CBH2 cellulases and related polynucleotides
EP2295535A1 (en) * 2009-09-11 2011-03-16 Mead Johnson Nutrition Company Probiotic material
WO2011035105A1 (en) 2009-09-18 2011-03-24 Codexis, Inc. Reduced codon mutagenesis
PL2504017T3 (pl) 2009-11-25 2014-06-30 Codexis Inc Rekombinacyjne warianty beta-glukozydazy do wytwarzania rozpuszczalnych cukrów z biomasy celulozowej
EP2504431A4 (en) 2009-11-25 2013-10-16 Codexis Inc RECOMBINANT BETA-GLUCOSIDASE VARIANTS OF THERMOASCUS AURIENTIACUS FOR THE PRODUCTION OF FERMENTABLE SUGARS FROM CELLULOSIC BIOMASS
PH12012501050A1 (en) 2009-12-08 2013-02-04 Nestec Sa Infant formula with probiotics and milk fat globule membrane components
CN102884178B (zh) 2009-12-08 2014-12-03 科德克希思公司 拉唑化合物的合成
US20110191903A1 (en) 2009-12-31 2011-08-04 Pioneer Hi-Bred International, Inc. Engineering plant resistance to diseases caused by pathogens
EP2566497B1 (en) 2010-05-04 2015-07-29 Codexis, Inc. Biocatalysts for ezetimibe synthesis
JP2013528374A (ja) 2010-05-10 2013-07-11 パーシード セラピューティクス リミテッド ライアビリティ カンパニー Ｖｌａ４のポリペプチド阻害剤
EP2576804B1 (en) 2010-05-28 2016-12-14 Codexis, Inc. Pentose fermentation by a recombinant microorganism
US8852900B2 (en) 2010-06-17 2014-10-07 Codexis, Inc. Biocatalysts and methods for the synthesis of (S)-3-(1-aminoethyl)-phenol
WO2012006114A2 (en) 2010-06-28 2012-01-12 Codexis, Inc. Fatty alcohol forming acyl reductases (fars) and methods of use thereof
AU2011272878B2 (en) 2010-06-30 2015-04-23 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
WO2012024100A2 (en) 2010-08-16 2012-02-23 Merck Sharp & Dohme Corp. Process for preparing aminocyclohexyl ether compounds
ES2623288T3 (es) 2010-08-20 2017-07-10 Codexis, Inc. Uso de proteínas de la familia de glicólido hidrolasa 61 en el procesamiento de celulosa
EP2649187B1 (en) 2010-12-08 2017-11-22 Codexis, Inc. Biocatalysts and methods for the synthesis of armodafinil
EP2691517A4 (en) 2011-03-30 2015-04-22 Codexis Inc FERMENTATION OF PENTOSES BY A RECOMBINANT MICROORGANISM
US9102963B2 (en) 2011-04-13 2015-08-11 Codexis, Inc. Biocatalytic process for preparing eslicarbazepine and analogs thereof
UA111078C2 (uk) * 2011-05-03 2016-03-25 Нестек С.А. Гідролізат білкового субстрату і спосіб його виготовлення
BR112013033614A2 (pt) 2011-06-30 2018-05-29 Codexis Inc fermentação de pentose por microorganismo recombinante
EP2748317B1 (en) 2011-08-22 2017-04-19 Codexis, Inc. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity
WO2013036861A1 (en) 2011-09-08 2013-03-14 Codexis, Inc Biocatalysts and methods for the synthesis of substituted lactams
EP2760997A4 (en) 2011-09-30 2015-02-11 Codexis Inc MUSHROOM PROTEASE
WO2013052101A1 (en) * 2011-10-03 2013-04-11 Kelly Foods Corporation Probiotic composition for pets and method of providing the same
US20130089638A1 (en) * 2011-10-11 2013-04-11 Mead Johnson Nutrition Company Compositions Comprising Maltotriose And Methods Of Using Same To Inhibit Damage Caused By Dehydration Processes
CN106479990B (zh) 2011-11-18 2020-09-18 科德克希思公司 用于制备羟基取代的氨基甲酸酯的生物催化剂
EP2794871A4 (en) 2011-12-20 2015-12-30 Codexis Inc VARIANTS OF ENDOGLUCANASE-1B (EG1B)
US20130251829A1 (en) * 2012-03-23 2013-09-26 Mead Johnson Nutrition Company Probiotic derived non-viable material for infection prevention and treatment
EP2828385B1 (en) 2012-03-23 2018-02-07 Codexis, Inc. Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
HUE042605T2 (hu) 2012-05-08 2019-07-29 Codexis Inc Biokatalizátorok és kémiai vegyületek hidroxilálására szolgáló eljárások
CN107904216B (zh) 2012-05-11 2021-06-29 科德克希思公司 工程化亚胺还原酶以及用于酮和胺化合物的还原胺化的方法
US8980578B2 (en) 2012-06-11 2015-03-17 Codexis, Inc. Fungal beta-xylosidase variants
CA2891482A1 (en) 2012-11-20 2014-05-30 Codexis, Inc. Pentose fermentation by a recombinant microorganism
WO2014088984A1 (en) 2012-12-07 2014-06-12 Merck Sharp & Dohme Corp. Biocatalytic transamination process
CN105008528A (zh) 2012-12-21 2015-10-28 科德克希思公司 用于合成手性胺的工程化的生物催化剂和方法
HUE044110T2 (hu) 2013-01-18 2019-09-30 Codexis Inc Módosított biokatalizátorok, amelyek alkalmasak karbapeném szintézisére
ES2694327T3 (es) 2013-02-28 2018-12-19 Codexis, Inc. Polipéptidos de transaminasa modificados por biocatálisis industrial
CN103355405A (zh) * 2013-04-07 2013-10-23 苏州旭优食品科技有限公司 一种低过敏性含乳制品的加工工艺
HRP20190928T1 (hr) 2013-04-18 2019-07-26 Codexis, Inc. Modificirani fenilalanin amonijak-liazni polipeptidi
HUE053379T2 (hu) 2013-11-13 2021-06-28 Codexis Inc Génmódosított imin-reduktázok és eljárások keton és amin vegyületek reduktív aminálására
EP3928787A1 (en) 2014-04-16 2021-12-29 Codexis, Inc. Engineered tyrosine ammonia lyase
WO2016007623A1 (en) 2014-07-09 2016-01-14 Codexis, Inc. Novel p450-bm3 variants with improved activity
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
DK3224354T3 (da) 2014-11-25 2021-03-01 Codexis Inc Manipulerede iminreductaser og fremgangsmåder til den reduktive aminering af keton- og aminforbindelser
HUE062016T2 (hu) 2014-12-22 2023-09-28 Codexis Inc Humán alfa-galaktozidáz variánsok
DK3256577T3 (da) 2015-02-10 2020-09-14 Codexis Inc Ketoreduktase polypeptider til syntesen af chirale forbindelser
JP6755886B2 (ja) 2015-05-07 2020-09-16 コデクシス， インコーポレイテッド ペニシリンｇアシラーゼ
US9683220B2 (en) 2015-07-07 2017-06-20 Codexis, Inc. P450-BM3 variants with improved activity
SG11201808957UA (en) 2016-05-05 2018-11-29 Codexis Inc Penicillin-g acylases
CN109715817B (zh) 2016-06-09 2022-12-09 科德克希思公司 用于化合物的羟基化的生物催化剂和方法
AU2017284104B2 (en) 2016-06-15 2020-06-25 Codexis, Inc. Engineered beta-glucosidases and glucosylation methods
CN109863162B (zh) 2016-08-26 2023-03-17 科德克希思公司 工程化亚胺还原酶和用于酮和胺化合物的还原胺化的方法
JP7019202B2 (ja) 2017-01-05 2022-02-15 コデクシス， インコーポレイテッド ペニシリンｇアシラーゼ
IL268121B2 (en) 2017-02-03 2024-01-01 Codexis Inc Engineered glycosyltransferases and steviol glycoside glucosylation methods
BR112019016634A2 (pt) 2017-02-13 2020-04-07 Codexis Inc polipeptídeos, sequência de polinucleotídeos modificados por engenharia, vetor de expressão, célula hospedeira, métodos para produzir um polipeptídeo de fenilalanina amônia liase modificado por engenharia em uma célula hospedeira e para tratar e/ou prevenir os sintomas de fenilcetonúria em um indivíduo, composição, e, uso
IL270068B (en) 2017-04-24 2022-06-01 Tesaro Inc Methods of manufacturing of niraparib
CN110831618B (zh) 2017-04-27 2023-08-25 科德克希思公司 酮还原酶多肽及多核苷酸
BR112019023337A2 (pt) 2017-05-08 2020-06-16 Codexis, Inc. Ligase engenheirada, sequência de polinucleotídeo, vetor de expressão, célula hospedeira, métodos para produzir um polipeptídeo da ligase engenheirada, um produto de ligação, uma biblioteca de dna e uma pluralidade de fragmentos de dna adequados para sequenciamento, e, composição
EP3638688A4 (en) 2017-06-14 2021-07-07 Codexis, Inc. MODIFIED TRANSAMINASE POLYPEPTIDES INTENDED FOR INDUSTRIAL BIOCATALYSIS
WO2019005337A1 (en) 2017-06-27 2019-01-03 Codexis, Inc. PENICILLIN G ACYLASES
KR20200023454A (ko) 2017-06-30 2020-03-04 코덱시스, 인코포레이티드 T7 rna 폴리머라제 변이체
EP3645711A4 (en) 2017-06-30 2021-04-21 Codexis, Inc. T7 RNA POLYMERASE VARIANTS
CA3080512A1 (en) 2017-11-07 2019-05-16 Codexis, Inc. Transglutaminase variants
EP4471137A3 (en) 2017-12-13 2025-02-19 GlaxoSmithKline Intellectual Property Development Ltd Carboxyesterase biocatalysts
CN111699250B (zh) 2017-12-13 2024-01-09 科德克希思公司 用于酰胺偶联的羧酸酯酶多肽
CA3102968A1 (en) 2018-06-12 2019-12-19 Codexis, Inc. Engineered tyrosine ammonia lyase
WO2020014050A1 (en) 2018-07-09 2020-01-16 Codexis, Inc. Engineered pantothenate kinase variant enzymes
JP7462969B2 (ja) 2018-07-09 2024-04-08 コデクシス， インコーポレイテッド 操作されたデオキシリボースリン酸アルドラーゼ
AU2019302422B2 (en) 2018-07-09 2022-08-04 Codexis, Inc. Engineered phosphopentomutase variant enzymes
US11162105B2 (en) 2018-07-09 2021-11-02 Codexis, Inc. Engineered purine nucleoside phosphorylase variant enzymes
AU2019300837B2 (en) 2018-07-09 2025-05-22 Codexis, Inc. Engineered galactose oxidase variant enzymes
US11198861B2 (en) 2018-07-12 2021-12-14 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
EP3830106A4 (en) 2018-07-30 2022-07-06 Codexis, Inc. MANIPULATED GLYCOSYLTRANSFERASES AND METHODS FOR STEVIOL GLYCOSIDE GLUCOSYLATION
KR20210084590A (ko) 2018-10-29 2021-07-07 코덱시스, 인코포레이티드 조작된 dna 중합효소 변이체
AU2019397401A1 (en) 2018-12-14 2021-06-17 Codexis, Inc. Engineered tyrosine ammonia lyase
KR102898199B1 (ko) 2018-12-20 2025-12-09 코덱시스, 인코포레이티드 인간 알파 갈락토시다제 변이체
WO2020150125A1 (en) 2019-01-15 2020-07-23 Codexis, Inc. Engineered transaminase polypeptides
SG11202110852RA (en) 2019-05-01 2021-10-28 Codexis Inc Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
EP3963058A4 (en) 2019-05-01 2024-01-03 Codexis, Inc. MODIFIED GLUCOSE DEHYDROGENASES AND PROCESSES FOR THE REDUCTIVE AMINATION OF KETONE AND AMINO COMPOUNDS
WO2021003129A2 (en) 2019-07-02 2021-01-07 Codexis, Inc. Engineered acetate kinase variant enzymes
JP7678580B2 (ja) 2019-07-02 2025-05-16 コデクシス， インコーポレイテッド 操作されたスクロースホスホリラーゼバリアント酵素
CN114144078B (zh) 2019-07-23 2024-06-11 菲仕兰坎皮纳荷兰公司 包含乳脂肪和免疫球蛋白的营养组合物
CA3152763A1 (en) 2019-08-30 2021-03-04 Codexis, Inc. Engineered lipase variants
CA3149870A1 (en) 2019-09-12 2021-03-18 Codexis, Inc. Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine
WO2021067608A1 (en) 2019-10-02 2021-04-08 Abbott Laboratories Detection of analytes by protein switches
CA3160437A1 (en) 2019-11-26 2021-06-03 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
JP2023507575A (ja) 2019-12-20 2023-02-24 コデクシス， インコーポレイテッド 操作された酸性アルファ－グルコシダーゼバリアント
IL295169A (en) 2020-02-04 2022-09-01 Codexis Inc Engineered leucine decarboxylases
CN115427557A (zh) 2020-04-10 2022-12-02 科德克希思公司 工程化转氨酶多肽
CN117098847A (zh) 2020-08-28 2023-11-21 科德克希思公司 工程化蛋白酶变体
MX2023002421A (es) 2020-08-28 2023-05-18 Codexis Inc Variantes de amilasa modificadas geneticamente.
WO2022125960A1 (en) 2020-12-11 2022-06-16 Willow Biosciences, Inc. Recombinant acyl activating enzyme (aae) genes for enhanced biosynthesis of cannabinoids and cannabinoid precursors
EP4262804A4 (en) 2020-12-18 2025-02-12 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
US11913036B2 (en) 2021-04-02 2024-02-27 Codexis, Inc. Engineered acetate kinase variant enzymes
IL305924B2 (en) 2021-04-02 2025-09-01 Codexis Inc Engineered Cyclic GMP-AMP Synthase (CGAS) Variant Enzymes
IL305922A (en) 2021-04-02 2023-11-01 Codexis Inc Transgenic enzymes of variant guanylate kinase
CN117120600A (zh) 2021-04-02 2023-11-24 科德克希思公司 工程化腺苷酸激酶变体酶
TW202313969A (zh) 2021-05-21 2023-04-01 美商克迪科思股份有限公司 經工程化的甲硫胺酸γ解離酶變異體
CA3227215A1 (en) 2021-07-30 2023-02-02 Trish Choudhary Recombinant prenyltransferase polypeptides engineered for enhanced biosynthesis of cannabinoids
CA3227236A1 (en) 2021-08-19 2023-02-23 Trish Choudhary Recombinant olivetolic acid cyclase polypeptides engineered for enhanced biosynthesis of cannabinoids
EP4416278A4 (en) 2021-10-15 2026-01-14 Codexis Inc MODIFIED DNA POLYMERASE VARIANTS
WO2023069921A1 (en) 2021-10-19 2023-04-27 Epimeron Usa, Inc. Recombinant thca synthase polypeptides engineered for enhanced biosynthesis of cannabinoids
US12502421B2 (en) 2021-11-01 2025-12-23 Syntis Bio, Inc. Engineered leucine decarboxylases
US20250207108A1 (en) 2022-03-31 2025-06-26 Qingdao Kingagroot Chemical Compound Co., Ltd. Monoamine oxidase and application thereof
WO2024040020A1 (en) 2022-08-15 2024-02-22 Absci Corporation Quantitative affinity activity specific cell enrichment
IL322082A (en) 2023-01-12 2025-09-01 Novartis Ag Engineered ketoreductase polypeptides
WO2025061911A1 (en) 2023-09-22 2025-03-27 Glaxosmithkline Intellectual Property Development Limited Methods of producing nucleotide triphosphates (ntps)
WO2025144700A1 (en) 2023-12-27 2025-07-03 Absci Corporation Nanobody library screening using bacterial surface display
WO2025235589A1 (en) 2024-05-08 2025-11-13 Codexis, Inc. Dna polymerase variants
WO2025242702A1 (en) 2024-05-23 2025-11-27 Glaxosmithkline Intellectual Property Development Limited Enzymatic process for producing n-acetyl galactosamine clusters

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886288A (en) * 1970-06-15 1975-05-27 Swift & Co Cheese manufacture using highly active proteolytic enzymes
JPS5279086A (en) 1975-12-25 1977-07-02 Nippon Soda Co Ltd Preparation of antibiotic tunicamycin
JPS5279083A (en) * 1975-12-26 1977-07-02 Morinaga Milk Industry Co Ltd Production of protein decomposed substance not having bitterness and antigen property
JPS6041751B2 (ja) 1976-06-22 1985-09-18 ジエコ−株式会社 デジタル電子時計
JPS548785A (en) 1977-06-21 1979-01-23 Kikkoman Corp Preparation of protein hydrolyzate
US4839281A (en) † 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
DK589785A (da) 1985-12-18 1987-06-19 Samuelsson Ernst Gunnar Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet
EP0322589B1 (fr) † 1987-12-23 1993-01-20 Societe Des Produits Nestle S.A. Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques
DD281540A5 (de) * 1988-08-08 1990-08-15 Berlin Chemie Veb Verfahren zur herstellung von nutritiva
DK0421309T4 (da) † 1989-10-02 2003-04-22 Associated British Foods Plc Proteinhydrolysater
JP3071877B2 (ja) † 1991-06-27 2000-07-31 財団法人糧食研究会 経口寛容誘導能を有する低アレルゲン性酵素分解ペプチド組成物
US5952034A (en) * 1991-10-12 1999-09-14 The Regents Of The University Of California Increasing the digestibility of food proteins by thioredoxin reduction
EP0577903B1 (fr) * 1992-07-06 1997-12-17 Societe Des Produits Nestle S.A. Agent antigastrite
FI94089C (fi) 1992-12-10 1995-07-25 Valio Oy Menetelmä allergiaa aiheuttavien yhdisteiden poistamiseksi proteiinipitoisista koostumuksista
RU2031586C1 (ru) 1993-02-05 1995-03-27 Тамара Георгиевна Извекова Биологически активный кисломолочный продукт "ацидолакт-наринэ" и способ его получения
GB9312369D0 (en) * 1993-06-16 1993-07-28 Sandoz Nutrition Ltd Organic compounds
WO1995014485A1 (en) † 1993-11-23 1995-06-01 Kabushiki Kaisha Wado Doctors Group Intestinal flora improver composition, and apparatus and system for producing the same
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012126481A1 (en) 2011-02-25 2012-09-27 OÜ Tervisliku Piima Biotehnoloogiate Arenduskeskus Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use

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