EE200400010A - 4-[4-[4-(hüdroksüdifenüülmetüül)-1-piperidinüül]-1-hüdroksübutüül]-a,a-dimetüülben seenäädikhappe ja selle hüdrokloriidi uued kristalsed vormid - Google Patents
4-[4-[4-(hüdroksüdifenüülmetüül)-1-piperidinüül]-1-hüdroksübutüül]-a,a-dimetüülben seenäädikhappe ja selle hüdrokloriidi uued kristalsed vormidInfo
- Publication number
- EE200400010A EE200400010A EEP200400010A EEP200400010A EE200400010A EE 200400010 A EE200400010 A EE 200400010A EE P200400010 A EEP200400010 A EE P200400010A EE P200400010 A EEP200400010 A EE P200400010A EE 200400010 A EE200400010 A EE 200400010A
- Authority
- EE
- Estonia
- Prior art keywords
- hydroxydiphenylmethyl
- hydroxybutyl
- piperidinyl
- hydrochloride
- crystalline forms
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- RWTNPBWLLIMQHL-UHFFFAOYSA-N fexofenadine Chemical compound C1=CC(C(C)(C(O)=O)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 RWTNPBWLLIMQHL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN484MA2001 | 2001-06-18 | ||
| PCT/US2001/023994 WO2002102777A2 (en) | 2001-06-18 | 2001-07-31 | NOVEL CRYSTALLINE FORMS OF 4-[4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERINDINYL]-1-HYDROXYBUTYL]-α, α-DIMETHYLBENZENE ACETIC ACID AND ITS HYDROCHLORIDE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200400010A true EE200400010A (et) | 2004-02-16 |
Family
ID=34566868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200400010A EE200400010A (et) | 2001-06-18 | 2001-07-31 | 4-[4-[4-(hüdroksüdifenüülmetüül)-1-piperidinüül]-1-hüdroksübutüül]-a,a-dimetüülben seenäädikhappe ja selle hüdrokloriidi uued kristalsed vormid |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP2261209A1 (pt) |
| JP (2) | JP2005507374A (pt) |
| KR (1) | KR20040015734A (pt) |
| CN (1) | CN100390145C (pt) |
| AU (1) | AU2001278094B2 (pt) |
| BG (1) | BG108435A (pt) |
| BR (1) | BR0117054A (pt) |
| CA (2) | CA2450858C (pt) |
| CO (1) | CO5540340A2 (pt) |
| CZ (1) | CZ20033358A3 (pt) |
| EE (1) | EE200400010A (pt) |
| HU (1) | HUP0401546A2 (pt) |
| IL (2) | IL159266A0 (pt) |
| MX (1) | MXPA03011728A (pt) |
| NZ (1) | NZ530118A (pt) |
| PL (1) | PL367632A1 (pt) |
| RU (1) | RU2269516C2 (pt) |
| SK (1) | SK15372003A3 (pt) |
| WO (1) | WO2002102777A2 (pt) |
| ZA (1) | ZA200309557B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002305162A1 (en) * | 2001-04-09 | 2002-10-21 | Teva Pharmaceutical Industries Ltd. | Polymorphs of fexofenadine hydrochloride |
| AU2003248657A1 (en) * | 2002-06-10 | 2003-12-22 | Teva Pharmaceutical Industries Ltd. | Polymorphic form xvi of fexofenadine hydrochloride |
| GB0319935D0 (en) | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
| MXPA06012281A (es) * | 2004-04-26 | 2007-07-18 | Teva Pharma | Formas cristalinas de clorhidrato de fexofenadina y procesos para su preparacion. |
| ITMI20041143A1 (it) * | 2004-06-08 | 2004-09-08 | Dipharma Spa | Polimorfi di fexofenadina e procedimento per la loro preparazione |
| ITMI20041568A1 (it) * | 2004-07-30 | 2004-10-30 | Dipharma Spa | "polimorfi di fexofenadina base" |
| JP2008514641A (ja) * | 2004-09-28 | 2008-05-08 | テバ ファーマシューティカル インダストリーズ リミティド | 結晶形フェキソフェナジン、およびその調製方法 |
| WO2007007347A1 (en) * | 2005-07-07 | 2007-01-18 | Wockhardt Limited | Industrial process of fexofenadine hydrochloride with controlled side products |
| RU2283649C1 (ru) * | 2005-10-27 | 2006-09-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения аллергических заболеваний |
| US20090306135A1 (en) | 2008-03-24 | 2009-12-10 | Mukesh Kumar Sharma | Stable amorphous fexofenadine hydrochloride |
| CN104072402B (zh) * | 2014-07-16 | 2016-08-17 | 昆山龙灯瑞迪制药有限公司 | 一种新结晶形式的盐酸非索非那定化合物及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4254129A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
| DK0701443T4 (da) * | 1992-08-03 | 2000-12-18 | Sepracor Inc | Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser |
| EP1178041A1 (en) * | 1994-05-18 | 2002-02-06 | Aventis Pharmaceuticals Inc. | Process for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives |
| US6153754A (en) * | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| IN191492B (pt) | 1999-05-25 | 2003-12-06 | Ranbaxy Lab Ltd | |
| GB0018691D0 (en) * | 2000-07-28 | 2000-09-20 | Rolabo Sl | Process |
-
2001
- 2001-07-31 IL IL15926601A patent/IL159266A0/xx unknown
- 2001-07-31 CA CA002450858A patent/CA2450858C/en not_active Expired - Fee Related
- 2001-07-31 BR BR0117054-6A patent/BR0117054A/pt not_active Application Discontinuation
- 2001-07-31 EP EP10010066A patent/EP2261209A1/en not_active Withdrawn
- 2001-07-31 KR KR10-2003-7016163A patent/KR20040015734A/ko not_active Ceased
- 2001-07-31 SK SK1537-2003A patent/SK15372003A3/sk unknown
- 2001-07-31 EE EEP200400010A patent/EE200400010A/xx unknown
- 2001-07-31 CZ CZ20033358A patent/CZ20033358A3/cs unknown
- 2001-07-31 RU RU2004101045/04A patent/RU2269516C2/ru not_active IP Right Cessation
- 2001-07-31 WO PCT/US2001/023994 patent/WO2002102777A2/en not_active Ceased
- 2001-07-31 JP JP2003505320A patent/JP2005507374A/ja active Pending
- 2001-07-31 EP EP01956057A patent/EP1399422A2/en not_active Withdrawn
- 2001-07-31 AU AU2001278094A patent/AU2001278094B2/en not_active Ceased
- 2001-07-31 CN CNB018233791A patent/CN100390145C/zh not_active Expired - Fee Related
- 2001-07-31 NZ NZ530118A patent/NZ530118A/en unknown
- 2001-07-31 HU HU0401546A patent/HUP0401546A2/hu unknown
- 2001-07-31 MX MXPA03011728A patent/MXPA03011728A/es active IP Right Grant
- 2001-07-31 CA CA002646802A patent/CA2646802A1/en not_active Abandoned
- 2001-07-31 PL PL01367632A patent/PL367632A1/xx not_active Application Discontinuation
-
2003
- 2003-12-09 ZA ZA200309557A patent/ZA200309557B/xx unknown
- 2003-12-09 IL IL159266A patent/IL159266A/en not_active IP Right Cessation
- 2003-12-11 BG BG108435A patent/BG108435A/xx unknown
- 2003-12-18 CO CO03110519A patent/CO5540340A2/es not_active Application Discontinuation
-
2007
- 2007-11-06 JP JP2007289084A patent/JP2008094848A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002102777A8 (en) | 2003-10-30 |
| JP2005507374A (ja) | 2005-03-17 |
| KR20040015734A (ko) | 2004-02-19 |
| RU2004101045A (ru) | 2005-06-27 |
| RU2269516C2 (ru) | 2006-02-10 |
| CN100390145C (zh) | 2008-05-28 |
| JP2008094848A (ja) | 2008-04-24 |
| CA2646802A1 (en) | 2002-12-27 |
| IL159266A0 (en) | 2004-06-01 |
| CN1518540A (zh) | 2004-08-04 |
| CA2450858A1 (en) | 2002-12-27 |
| CA2450858C (en) | 2009-04-07 |
| IL159266A (en) | 2010-11-30 |
| WO2002102777A2 (en) | 2002-12-27 |
| AU2001278094B2 (en) | 2006-01-12 |
| EP1399422A2 (en) | 2004-03-24 |
| ZA200309557B (en) | 2004-09-14 |
| NZ530118A (en) | 2007-05-31 |
| HUP0401546A2 (hu) | 2004-12-28 |
| WO2002102777A3 (en) | 2003-02-27 |
| SK15372003A3 (sk) | 2004-08-03 |
| PL367632A1 (en) | 2005-03-07 |
| BG108435A (en) | 2004-12-30 |
| CO5540340A2 (es) | 2005-07-29 |
| CZ20033358A3 (en) | 2004-04-14 |
| BR0117054A (pt) | 2004-07-27 |
| EP2261209A1 (en) | 2010-12-15 |
| MXPA03011728A (es) | 2004-07-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EE200400010A (et) | 4-[4-[4-(hüdroksüdifenüülmetüül)-1-piperidinüül]-1-hüdroksübutüül]-a,a-dimetüülben seenäädikhappe ja selle hüdrokloriidi uued kristalsed vormid | |
| LTPA2017032I1 (lt) | Pirolidino ir piperidino dariniai kaip NK1 antagonistai | |
| NO20013538L (no) | Piperidin, tetrahydropyridin og piperazinderivater, deres fremstilling og anvendelse | |
| NO20023319D0 (no) | Substituerte glutarimider og deres anvendelse som inhibitorer av IL-12-produksjonen | |
| NO20000115D0 (no) | Gastrokinetiske monocykliske benzamider av 3- eller 4- substituerte 4-(aminometyl)-piperidinderivater | |
| NO20026125L (no) | Tetrahydropyridin- eller piperidin-heterocykliske derivater | |
| NO20015365D0 (no) | Piperidinderivater som er anvendbare som CCR5-antagonister | |
| NO20023293D0 (no) | Piperidin- og piperazinderivater som virker som 5-HT2A- reseptorantagonister | |
| HRP20041198B1 (hr) | Farmaceutski pripravci koji sadrže stabiliziranu amorfnu formu donepezil hidroklorida | |
| DE60203481D1 (de) | Piperidinderivate als neurokinin 1 antagonisten | |
| WO2001094313A3 (en) | Crystal modification of fexofenadine | |
| ATE347550T1 (de) | Polymorph von 4-(2-(4-(1-(2-ethoxyethyl)-1h- benzimidazol-2-yl)-1-piperidinyl)ethyl)-alpha, alpha-dimethylbenzolessigsäure | |
| AU2003245029A1 (en) | Novel crystalline forms of donepezil hydrochloride | |
| HUP0201673A3 (en) | Process for the preparation of 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-alpha, alpha-dimethylbenzeneacetic acid | |
| PL325264A1 (en) | Novel derivatives of phenyl-alpha,alpha-dimethylacetic acid, method of obtaining such derivatives, method of obtaining a pharmaceutic agent, application of such derivatives and method of obtaining 4-{4-[4-(hydroxydiphenylmethyl)piperidin]-1-hydroxybutyl}-phenyl-alpha,alpha-dimethylacetic acid | |
| NO20013832D0 (no) | Piperidin- og piperazinderivater som hemmere ved Abeta-fibril- dannelsen | |
| EP1616861A3 (en) | A process for the preparation of keto compounds | |
| NZ306319A (en) | 1-alkylphenyl substituted 4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butanol derivatives and medicaments | |
| UA72890C2 (en) | A crystalline form of osanetant (variants), a method for the preparation thereof (variants) and a pharmaceutical composition | |
| FI955916A7 (fi) | N-((1-(4-(4-fluorifenoksi)butyyli)-4-piperidinyyli)-N-metyyliamino)-2- bentsotiatsololeja luokan III rytmihäiriölääkkeinä | |
| IL152570A0 (en) | A process for the preparation of 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-alpha, alpha-di methylbenzeneacetic acid | |
| WO2007049303A3 (en) | An improved process for the preparation of highly pure fexofenadine | |
| ATE344244T1 (de) | Substituierte 4-phenyl-1-(1-phenyl-cyclohexyl)-1, 2,3,6-tetrahydropyridine | |
| IL191460A0 (en) | A process for the preparation of keto compounds | |
| IS7901A (is) | 4-(2-Fenýloxýfenýl)-píperidín eða -1,2,3,6-tetrahýdrópýridín afleiður sem serótónín endurupptöku hindrar |