NO20023319D0 - Substituerte glutarimider og deres anvendelse som inhibitorer av IL-12-produksjonen - Google Patents

Substituerte glutarimider og deres anvendelse som inhibitorer av IL-12-produksjonen

Info

Publication number: NO20023319D0
Authority: NO; Norway
Prior art keywords: inhibitors; production; substituted glutarimides; glutarimides; substituted
Prior art date: 2000-01-21

Application number

NO20023319A

Other languages

English (en)

Other versions

NO20023319L (no

NO323395B1 (no

Inventor

Tieno Germann

Stefanie Frosch

Erik Wade

Helmut Buschmann

Oswald Zimmer

Original Assignee

Gruenenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-21

Filing date

2002-07-09

Publication date

2002-07-09

2002-07-09 Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh

2002-07-09 Publication of NO20023319D0 publication Critical patent/NO20023319D0/no

2002-09-03 Publication of NO20023319L publication Critical patent/NO20023319L/no

2007-04-23 Publication of NO323395B1 publication Critical patent/NO323395B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Transplantation (AREA)
Ophthalmology & Optometry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Otolaryngology (AREA)

NO20023319A 2000-01-21 2002-07-09 Substituerte glutarimider som er inhibitorer av IL-12-produksjonen, fremgangsmate for fremstilling derav, anvendelse derav samt legemidler inneholdende forbindelsene. NO323395B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10002509A DE10002509A1 (de)	2000-01-21	2000-01-21	Substituierte Glutarimide
PCT/EP2001/000155 WO2001053261A1 (de)	2000-01-21	2001-01-09	Substituierte glutarimide und ihre verwendung als inhibitoren der il-12 produktion

Publications (3)

Publication Number	Publication Date
NO20023319D0 true NO20023319D0 (no)	2002-07-09
NO20023319L NO20023319L (no)	2002-09-03
NO323395B1 NO323395B1 (no)	2007-04-23

Family

ID=7628270

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20023319A NO323395B1 (no)	2000-01-21	2002-07-09	Substituerte glutarimider som er inhibitorer av IL-12-produksjonen, fremgangsmate for fremstilling derav, anvendelse derav samt legemidler inneholdende forbindelsene.

Country Status (28)

Country	Link
US (2)	US6656937B2 (no)
EP (1)	EP1252144B1 (no)
JP (1)	JP2003524641A (no)
KR (1)	KR20020067614A (no)
CN (1)	CN1185215C (no)
AR (1)	AR030185A1 (no)
AT (1)	ATE451355T1 (no)
AU (1)	AU780636B2 (no)
BR (1)	BR0108030A (no)
CA (1)	CA2398061A1 (no)
CO (1)	CO5261626A1 (no)
CY (1)	CY1109784T1 (no)
DE (2)	DE10002509A1 (no)
DK (1)	DK1252144T3 (no)
ES (1)	ES2337875T3 (no)
HU (1)	HUP0204235A3 (no)
IL (1)	IL150813A0 (no)
MX (1)	MXPA02007089A (no)
NO (1)	NO323395B1 (no)
NZ (1)	NZ520759A (no)
PE (1)	PE20011067A1 (no)
PL (1)	PL356986A1 (no)
PT (1)	PT1252144E (no)
RU (1)	RU2278857C2 (no)
SI (1)	SI1252144T1 (no)
SK (1)	SK287173B6 (no)
WO (1)	WO2001053261A1 (no)
ZA (1)	ZA200206664B (no)

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DE10002509A1 (de) *	2000-01-21	2001-07-26	Gruenenthal Gmbh	Substituierte Glutarimide
US7193105B2 (en) *	2002-05-22	2007-03-20	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors based on trihalomethylcarbonyl compounds
US7842727B2 (en)	2001-03-27	2010-11-30	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
US7057057B2 (en)	2002-05-22	2006-06-06	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
DE10163595A1 (de) *	2001-12-21	2003-08-07	Gruenenthal Gmbh	In 3-Position heterocyclisch substituierte Piperidin-2,6-dione
US20040192738A1 (en) *	2003-03-18	2004-09-30	Aventis Pharma Deutschland Gmbh	2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it
KR20060124770A (ko)	2004-03-17	2006-12-05	화이자 프로덕츠 인코포레이티드	벤질(이덴)-락탐 유도체
DE102004026703A1 (de) *	2004-05-28	2005-12-29	Grünenthal GmbH	Verfahren zur Herstellung von in 3-Position heterocyclisch substituierten Piperidin-2,6-dionen
JP6450323B2 (ja) *	2013-01-07	2019-01-09	ユニバーシティオブサザンカリフォルニア	デオキシウリジントリホスファターゼ阻害剤
EA032938B1 (ru)	2013-04-12	2019-08-30	Общество С Ограниченной Ответственностью "Атд Терапевтикс"	Производное глутаримидов, его применение, фармацевтическая композиция на его основе, способ его получения
WO2015103489A1 (en)	2014-01-03	2015-07-09	University Of Southern California	Heteroatom containing deoxyuridine triphosphatase inhibitors
US10544105B2 (en)	2015-07-08	2020-01-28	Cv6 Therapeutics (Ni) Limited	Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
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US10570100B2 (en)	2015-07-08	2020-02-25	University Of Southern California	Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
US10577321B2 (en)	2015-07-08	2020-03-03	University Of Southern California	Deoxyuridine triphosphatase inhibitors
RU2610275C2 (ru) *	2015-07-30	2017-02-08	Общество С Ограниченной Ответственностью "Фарминтерпрайсез"	Производное глутаримидов, его применение, фармацевтическая композиция на его основе, способ его получения
CN109153644B (zh) *	2016-03-16	2022-10-21	H·李·莫菲特癌症中心研究有限公司	用以增强效应t细胞功能的针对cereblon的小分子
WO2018098208A1 (en)	2016-11-23	2018-05-31	Cv6 Therapeutics (Ni) Limited	Nitrogen ring linked deoxyuridine triphosphatase inhibitors
US11168059B2 (en)	2016-11-23	2021-11-09	Cv6 Therapeutics (Ni) Limited	Amino sulfonyl compounds
US11174271B2 (en)	2016-11-23	2021-11-16	Cv6 Therapeutics (Ni) Limited	6-membered uracil isosteres
US11014924B2 (en)	2016-11-23	2021-05-25	Cv6 Therapeutics (Ni) Limited	Hydantoin containing deoxyuridine triphosphatase inhibitors
WO2018098206A1 (en)	2016-11-23	2018-05-31	Cv6 Therapeutics (Ni) Limited	Hydantoin containing deoxyuridine triphosphatase inhibitors
US11247984B2 (en)	2017-01-05	2022-02-15	Cv6 Therapeutics (Ni) Limited	Uracil containing compounds
GEP20227354B (en)	2017-09-07	2022-02-25	Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises	Use of a glutarimide derivative to treat diseases related to the aberrant activity of cytokines
IL273432B (en)	2017-09-22	2022-09-01	Kymera Therapeutics Inc	Protein compounds and their uses
US11358948B2 (en)	2017-09-22	2022-06-14	Kymera Therapeutics, Inc.	CRBN ligands and uses thereof
IL315310A (en)	2017-12-26	2024-10-01	Kymera Therapeutics Inc	Irak degraders and uses thereof
WO2019140380A1 (en) *	2018-01-12	2019-07-18	Kymera Therapeutics, Inc.	Protein degraders and uses thereof
EP3737675A4 (en) *	2018-01-12	2022-01-05	Kymera Therapeutics, Inc.	Crbn ligands and uses thereof
CN107903245B (zh) *	2018-01-15	2018-11-13	青岛大学附属医院	一种化合物及其在制备治疗类风湿性关节炎药物中的应用
CN107857754B (zh) *	2018-01-15	2018-11-09	泰山医学院	一种化合物及其在制备预防/治疗类风湿性关节炎药物中的应用
EP3817822A4 (en)	2018-07-06	2022-07-27	Kymera Therapeutics, Inc.	PROTEIN DEGRADANTS AND USES THEREOF
WO2020010177A1 (en)	2018-07-06	2020-01-09	Kymera Therapeutics, Inc.	Tricyclic crbn ligands and uses thereof
CN112512589A (zh)	2018-07-11	2021-03-16	H·李·莫菲特癌症中心研究有限公司	二聚体免疫调节化合物对抗基于cereblon的机制
CA3119773A1 (en)	2018-11-30	2020-06-04	Kymera Therapeutics, Inc.	Irak degraders and uses thereof
CN120574283A (zh)	2019-04-05	2025-09-02	凯麦拉医疗公司	Stat降解剂和其用途
WO2020251972A1 (en)	2019-06-10	2020-12-17	Kymera Therapeutics, Inc.	Smarca degraders and uses thereof
EP4076524A4 (en)	2019-12-17	2023-11-29	Kymera Therapeutics, Inc.	IRAQ DEGRADERS AND USES THEREOF
JP2023509366A (ja)	2019-12-17	2023-03-08	カイメラセラピューティクス，インコーポレイテッド	Ｉｒａｋ分解剤およびそれらの使用
CN115297931A (zh)	2019-12-23	2022-11-04	凯麦拉医疗公司	Smarca降解剂和其用途
US12528785B2 (en)	2020-03-19	2026-01-20	Kymera Therapeutics, Inc.	MDM2 degraders and uses thereof
TW202210483A (zh)	2020-06-03	2022-03-16	美商凱麥拉醫療公司	Irak降解劑之結晶型
CN115803026A (zh) *	2020-06-26	2023-03-14	瓦伦塔有限责任公司	戊二酰亚胺衍生物用于治疗与异常白介素-6活性相关的疾病的用途
TW202241891A (zh)	2020-12-30	2022-11-01	美商凱麥拉醫療公司	Irak降解劑及其用途
US12171768B2 (en)	2021-02-15	2024-12-24	Kymera Therapeutics, Inc.	IRAK4 degraders and uses thereof
IL308314A (en)	2021-05-07	2024-01-01	Kymera Therapeutics Inc	CDK2 compounds and their uses
AR127505A1 (es)	2021-10-29	2024-01-31	Kymera Therapeutics Inc	Degradadores irak-4 y síntesis de los mismos
WO2023147594A2 (en)	2022-01-31	2023-08-03	Kymera Therapeutics, Inc.	Irak degraders and uses thereof

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DE10002509A1 (de) *	2000-01-21	2001-07-26	Gruenenthal Gmbh	Substituierte Glutarimide

2000
- 2000-01-21 DE DE10002509A patent/DE10002509A1/de not_active Ceased
2001
- 2001-01-09 ES ES01900400T patent/ES2337875T3/es not_active Expired - Lifetime
- 2001-01-09 HU HU0204235A patent/HUP0204235A3/hu unknown
- 2001-01-09 DK DK01900400.1T patent/DK1252144T3/da active
- 2001-01-09 IL IL15081301A patent/IL150813A0/xx unknown
- 2001-01-09 BR BR0108030-0A patent/BR0108030A/pt not_active IP Right Cessation
- 2001-01-09 RU RU2002121641/04A patent/RU2278857C2/ru not_active IP Right Cessation
- 2001-01-09 AU AU25140/01A patent/AU780636B2/en not_active Ceased
- 2001-01-09 PL PL01356986A patent/PL356986A1/xx not_active Application Discontinuation
- 2001-01-09 NZ NZ520759A patent/NZ520759A/en unknown
- 2001-01-09 JP JP2001553265A patent/JP2003524641A/ja not_active Withdrawn
- 2001-01-09 WO PCT/EP2001/000155 patent/WO2001053261A1/de not_active Ceased
- 2001-01-09 SI SI200130961T patent/SI1252144T1/sl unknown
- 2001-01-09 SK SK1017-2002A patent/SK287173B6/sk not_active IP Right Cessation
- 2001-01-09 MX MXPA02007089A patent/MXPA02007089A/es active IP Right Grant
- 2001-01-09 CN CNB018038883A patent/CN1185215C/zh not_active Expired - Fee Related
- 2001-01-09 KR KR1020027009243A patent/KR20020067614A/ko not_active Ceased
- 2001-01-09 DE DE50115252T patent/DE50115252D1/de not_active Expired - Lifetime
- 2001-01-09 EP EP01900400A patent/EP1252144B1/de not_active Expired - Lifetime
- 2001-01-09 CA CA002398061A patent/CA2398061A1/en not_active Abandoned
- 2001-01-09 AT AT01900400T patent/ATE451355T1/de not_active IP Right Cessation
- 2001-01-09 PT PT01900400T patent/PT1252144E/pt unknown
- 2001-01-19 AR ARP010100251A patent/AR030185A1/es unknown
- 2001-01-19 PE PE2001000061A patent/PE20011067A1/es not_active Application Discontinuation
- 2001-01-19 CO CO01003816A patent/CO5261626A1/es not_active Application Discontinuation
2002
- 2002-07-09 NO NO20023319A patent/NO323395B1/no not_active IP Right Cessation
- 2002-07-19 US US10/198,073 patent/US6656937B2/en not_active Expired - Fee Related
- 2002-08-20 ZA ZA200206664A patent/ZA200206664B/en unknown
2003
- 2003-09-03 US US10/653,188 patent/US20040048859A1/en not_active Abandoned
2010
- 2010-02-11 CY CY20101100143T patent/CY1109784T1/el unknown

Also Published As

Publication number	Publication date
EP1252144A1 (de)	2002-10-30
RU2002121641A (ru)	2004-01-10
SK10172002A3 (sk)	2003-02-04
ATE451355T1 (de)	2009-12-15
US20040048859A1 (en)	2004-03-11
JP2003524641A (ja)	2003-08-19
RU2278857C2 (ru)	2006-06-27
CN1185215C (zh)	2005-01-19
HUP0204235A2 (hu)	2003-03-28
IL150813A0 (en)	2003-02-12
NO20023319L (no)	2002-09-03
US6656937B2 (en)	2003-12-02
WO2001053261A1 (de)	2001-07-26
BR0108030A (pt)	2003-01-28
PT1252144E (pt)	2010-02-03
NZ520759A (en)	2005-09-30
AU2514001A (en)	2001-07-31
DE10002509A1 (de)	2001-07-26
AU780636B2 (en)	2005-04-07
SI1252144T1 (sl)	2010-04-30
ZA200206664B (en)	2004-01-21
EP1252144B1 (de)	2009-12-09
CO5261626A1 (es)	2003-03-31
MXPA02007089A (es)	2002-12-13
HUP0204235A3 (en)	2005-03-29
US20030064987A1 (en)	2003-04-03
DK1252144T3 (da)	2010-04-19
AR030185A1 (es)	2003-08-13
PE20011067A1 (es)	2001-12-29
NO323395B1 (no)	2007-04-23
SK287173B6 (sk)	2010-02-08
KR20020067614A (ko)	2002-08-22
DE50115252D1 (de)	2010-01-21
CN1394201A (zh)	2003-01-29
CY1109784T1 (el)	2014-09-10
ES2337875T3 (es)	2010-04-30
PL356986A1 (en)	2004-07-12
CA2398061A1 (en)	2001-07-26

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EP1185528A4 (en)	2003-03-26	INHIBITORS OF IL-12 PRODUCTION
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NO20025884L (no)	2003-01-29	2-aminotiazolinderivater og deres anvendelse som NO- syntaseinhibitorer
DE60008319D1 (de)	2004-03-25	IL-12 Produktionsinhibitor
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FIU20010310U0 (fi)	2001-08-15	Amlodipiinin aspartaatti derivaatti
HK1051361A (en)	2003-08-01	Substituted glutarimides and use thereof il-12 production inhibitors

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