[go: up one dir, main page]

EE200300248A - GABA agonistide ja sorbitooldehüdrogenaasi inhibiitorite kombinatsioon - Google Patents

GABA agonistide ja sorbitooldehüdrogenaasi inhibiitorite kombinatsioon

Info

Publication number
EE200300248A
EE200300248A EEP200300248A EEP200300248A EE200300248A EE 200300248 A EE200300248 A EE 200300248A EE P200300248 A EEP200300248 A EE P200300248A EE P200300248 A EEP200300248 A EE P200300248A EE 200300248 A EE200300248 A EE 200300248A
Authority
EE
Estonia
Prior art keywords
combination
dehydrogenase inhibitors
sorbitol dehydrogenase
gaba agonists
gaba
Prior art date
Application number
EEP200300248A
Other languages
English (en)
Estonian (et)
Inventor
Lakshman Mylari Banavara
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of EE200300248A publication Critical patent/EE200300248A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP200300248A 2000-11-30 2001-11-19 GABA agonistide ja sorbitooldehüdrogenaasi inhibiitorite kombinatsioon EE200300248A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25006900P 2000-11-30 2000-11-30
PCT/IB2001/002213 WO2002043762A2 (en) 2000-11-30 2001-11-19 Combination of gaba agonists and sorbitol dehydrogenase inhibitors

Publications (1)

Publication Number Publication Date
EE200300248A true EE200300248A (et) 2003-10-15

Family

ID=22946187

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300248A EE200300248A (et) 2000-11-30 2001-11-19 GABA agonistide ja sorbitooldehüdrogenaasi inhibiitorite kombinatsioon

Country Status (38)

Country Link
US (1) US6544998B2 (xx)
EP (1) EP1337271B1 (xx)
JP (1) JP2004514699A (xx)
KR (1) KR20030059290A (xx)
CN (1) CN1477975A (xx)
AP (1) AP2001002360A0 (xx)
AR (1) AR031431A1 (xx)
AT (1) ATE281181T1 (xx)
AU (1) AU2002215159A1 (xx)
BG (1) BG107774A (xx)
BR (1) BR0115783A (xx)
CA (1) CA2430298A1 (xx)
CR (1) CR6964A (xx)
CZ (1) CZ20031399A3 (xx)
DE (1) DE60106968T2 (xx)
DO (1) DOP2001000289A (xx)
EA (1) EA200300432A1 (xx)
EC (1) ECSP034624A (xx)
EE (1) EE200300248A (xx)
ES (1) ES2230378T3 (xx)
HR (1) HRP20030420A2 (xx)
HU (1) HUP0302160A3 (xx)
IL (1) IL155704A0 (xx)
IS (1) IS6786A (xx)
MA (1) MA26964A1 (xx)
MX (1) MXPA03004870A (xx)
NO (1) NO20032441L (xx)
OA (1) OA12534A (xx)
PA (1) PA8534101A1 (xx)
PE (1) PE20020597A1 (xx)
PL (1) PL365927A1 (xx)
PT (1) PT1337271E (xx)
SK (1) SK6192003A3 (xx)
SV (1) SV2003000751A (xx)
TN (1) TNSN01169A1 (xx)
UY (1) UY27042A1 (xx)
WO (1) WO2002043762A2 (xx)
ZA (1) ZA200303381B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100491282B1 (ko) 1996-07-24 2005-05-24 워너-램버트 캄파니 엘엘씨 통증 치료용 이소부틸가바 및 그의 유도체
US6992109B1 (en) * 1999-04-08 2006-01-31 Segal Catherine A Method for the treatment of incontinence
US7022678B2 (en) * 2001-03-30 2006-04-04 Warner-Lambert Company Pregabalin lactose conjugates
MXPA03009392A (es) * 2001-05-25 2004-01-29 Warner Lambert Co Composicion famaceutica liquida.
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
KR20050036195A (ko) * 2003-10-15 2005-04-20 고재영 신규한 망막병증 치료제 조성물
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
KR20070020022A (ko) * 2004-04-02 2007-02-16 임팩스 라보라토리즈, 인코포레이티드 Ｇａｂａ 수용체 효능제에 대한 제어 방출 제형
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
GB0420831D0 (en) 2004-09-17 2004-10-20 Glaxo Group Ltd Novel compounds
KR101063663B1 (ko) 2005-02-17 2011-09-07 아스텔라스세이야쿠 가부시키가이샤 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르유도체
GB0513553D0 (en) * 2005-07-01 2005-08-10 Fond D Amico Per La Ricerca Su Rab3a
TWI362930B (en) 2007-04-27 2012-05-01 Purdue Pharma Lp Trpv1 antagonists and uses thereof
ES2416723T3 (es) * 2007-10-09 2013-08-02 Merck Patent Gmbh Composiciones farmacéuticas que contienen benfotiamina y gabapentina
EP2116618A1 (en) 2008-05-09 2009-11-11 Agency for Science, Technology And Research Diagnosis and treatment of Kawasaki disease
JP5815552B2 (ja) 2009-12-08 2015-11-17 ケース ウェスタン リザーブ ユニバーシティＣａｓｅ Ｗｅｓｔｅｒｎｒｅｓｅｒｖｅ Ｕｎｉｖｅｒｓｉｔｙ 眼疾患を治療する化合物および方法
CN107050456B (zh) * 2010-09-28 2022-08-12 加利福尼亚大学董事会 治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合
KR101589837B1 (ko) 2011-06-22 2016-01-29 퍼듀 퍼머 엘피 디히드록시 치환기를 포함하는 trpv1 길항제 및 그의 용도
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12433904B2 (en) 2019-04-17 2025-10-07 Compass Pathfinder Limited Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
CA3136100A1 (en) * 2019-05-07 2020-11-12 Stephan L. ZUCHNER Treatment and detection of inherited neuropathies and associated disorders

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2409754A (en) 1946-10-22 Method for obtaining hydantoins
CH449645A (de) 1963-07-09 1968-01-15 Ciba Geigy Verfahren zur Herstellung neuer Aminosäuren
CH427803A (de) 1963-12-06 1967-01-15 Geigy Ag J R Verfahren zur Herstellung eines neuen Isoxazolderivates
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US3960927A (en) 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
FR2319338A1 (fr) * 1975-08-01 1977-02-25 Synthelabo Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent
JPS5625169A (en) 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4513006A (en) 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
DK288385D0 (da) 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
US6197819B1 (en) 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
KR950703539A (ko) * 1992-09-28 1995-09-20 알렌 제이. 스피겔 당뇨병 합병증 치료용 치환된 피리미딘(substituted pyrimidines for control or diabetic complications)
US6350769B1 (en) * 1999-02-24 2002-02-26 The Regents Of The University Of California Gaba alpha receptors mediate inhibition of T cell responses
ATE264311T1 (de) * 1999-04-01 2004-04-15 Pfizer Prod Inc Verbindungen zur behandlung und vorsorge bei diabetes
AU768720B2 (en) * 1999-04-01 2004-01-08 Pfizer Products Inc. Aminopyrimidines as sorbitol dehydrogenase inhibitors

Also Published As

Publication number Publication date
IS6786A (is) 2003-04-14
CN1477975A (zh) 2004-02-25
PL365927A1 (en) 2005-01-10
MXPA03004870A (es) 2003-08-19
UY27042A1 (es) 2002-07-31
EP1337271B1 (en) 2004-11-03
TNSN01169A1 (fr) 2005-11-10
IL155704A0 (en) 2003-11-23
NO20032441D0 (no) 2003-05-28
PA8534101A1 (es) 2002-10-31
CA2430298A1 (en) 2002-06-06
BR0115783A (pt) 2003-09-16
ECSP034624A (es) 2003-07-25
NO20032441L (no) 2003-07-03
DOP2001000289A (es) 2003-02-15
JP2004514699A (ja) 2004-05-20
DE60106968D1 (de) 2004-12-09
US20020091128A1 (en) 2002-07-11
HUP0302160A2 (hu) 2003-11-28
BG107774A (en) 2004-01-30
AR031431A1 (es) 2003-09-24
WO2002043762A2 (en) 2002-06-06
OA12534A (en) 2006-06-05
ATE281181T1 (de) 2004-11-15
CR6964A (es) 2004-02-02
MA26964A1 (fr) 2004-12-20
EP1337271A2 (en) 2003-08-27
AU2002215159A1 (en) 2002-06-11
KR20030059290A (ko) 2003-07-07
HUP0302160A3 (en) 2005-05-30
ZA200303381B (en) 2004-04-30
AP2001002360A0 (en) 2001-12-31
SK6192003A3 (en) 2004-07-07
DE60106968T2 (de) 2005-11-03
WO2002043762A3 (en) 2003-03-13
CZ20031399A3 (cs) 2004-04-14
PT1337271E (pt) 2005-01-31
ES2230378T3 (es) 2005-05-01
PE20020597A1 (es) 2002-07-08
SV2003000751A (es) 2003-01-13
HRP20030420A2 (en) 2004-08-31
EA200300432A1 (ru) 2003-10-30
US6544998B2 (en) 2003-04-08

Similar Documents

Publication Publication Date Title
EE200300248A (et) GABA agonistide ja sorbitooldehüdrogenaasi inhibiitorite kombinatsioon
EE200300249A (et) GABA agonistide ja aldoosreduktaasi inhibiitoritekombinatsioon
CY2015053I2 (el) Υδροξαμικα παραγωγα χρησιμα ως αναστολεις δεακετυλασης
IS6934A (is) Nýjar spírótrísýklískar afleiður og notkun þeirrasem fosfódíesterasa-7-hindrar
EE200200576A (et) Oksasooli derivaadid ja nende kasutamine türosiini kinaasi inhibiitoritena
GB0025782D0 (en) Use of inhibitors
NO20026283L (no) Inhibitorer av kobberholdige aminosydaser
NO20032668L (no) Gyraseinhibitorer og anvendelser derav
NO20026010L (no) Substituerte quinazolinderivater og deres anvendelse som inhibitorer
EE200300134A (et) Uued tiadiasoolid ja oksadiasoolid ning nende kasutamine fosfodiesteraas-7 inhibiitoritena
DK1251848T3 (da) Gyraseinhibitorer og anvendelse deraf
DK1307263T3 (da) Hidtil ukendt anvendelse af lipaseinhibitorer
NO20022988L (no) Vedvarende frigivelse (med dybdevirkning) av syklooksygenase- 2-inhibitor
NO20031139L (no) 2-amino-2-alkyl-4-heksen- og heksynsyrederivater som er anvendbare som nitrogenoksidsyntaseinhibitorer
HUP0300061A3 (en) Use of il-18 inhibitors
DK1317421T3 (da) 2-amino-2-alkyl-5-heptensyre- og heptynsyrederivater der er nyttige som nitrogenoxidsynthaseinhibitorer
DK1272488T3 (da) Tri-aryl-substitueret ethan-PDE4-inhibitorer
NO20031877D0 (no) Forebyggelse av korrosjon med fordelaktige biofilmer
NO20024481D0 (no) Difluorbutyrsyre metalloproteaseinhibitorer
DK1130214T3 (da) Korrosionsinhibitorer
IL154927A0 (en) Combination of statins and sorbitol dehydrogenase inhibitors
EP1222308A4 (en) INHIBITORS OF HISTONE ACETYL ANTIPROTOZOA TRANSFERASE
PL366012A1 (pl) Kompozycja i sposób oznaczania glikozydazy
SI1337271T1 (en) Combination of gaba agonists and sorbitol dehydrogenase inhibitors
AU1212002A (en) Use of lipase inhibitors