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BG107774A - Combination of gaba agonists and sorbitol dehydrogenase inhibitors - Google Patents

Combination of gaba agonists and sorbitol dehydrogenase inhibitors

Info

Publication number
BG107774A
BG107774A BG107774A BG10777403A BG107774A BG 107774 A BG107774 A BG 107774A BG 107774 A BG107774 A BG 107774A BG 10777403 A BG10777403 A BG 10777403A BG 107774 A BG107774 A BG 107774A
Authority
BG
Bulgaria
Prior art keywords
diabetic
prodrug
combinations
combination
gaba agonists
Prior art date
Application number
BG107774A
Other languages
Bulgarian (bg)
English (en)
Inventor
Banavara L. Mylari
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG107774A publication Critical patent/BG107774A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG107774A 2000-11-30 2003-05-07 Combination of gaba agonists and sorbitol dehydrogenase inhibitors BG107774A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25006900P 2000-11-30 2000-11-30
PCT/IB2001/002213 WO2002043762A2 (en) 2000-11-30 2001-11-19 Combination of gaba agonists and sorbitol dehydrogenase inhibitors

Publications (1)

Publication Number Publication Date
BG107774A true BG107774A (en) 2004-01-30

Family

ID=22946187

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107774A BG107774A (en) 2000-11-30 2003-05-07 Combination of gaba agonists and sorbitol dehydrogenase inhibitors

Country Status (38)

Country Link
US (1) US6544998B2 (xx)
EP (1) EP1337271B1 (xx)
JP (1) JP2004514699A (xx)
KR (1) KR20030059290A (xx)
CN (1) CN1477975A (xx)
AP (1) AP2001002360A0 (xx)
AR (1) AR031431A1 (xx)
AT (1) ATE281181T1 (xx)
AU (1) AU2002215159A1 (xx)
BG (1) BG107774A (xx)
BR (1) BR0115783A (xx)
CA (1) CA2430298A1 (xx)
CR (1) CR6964A (xx)
CZ (1) CZ20031399A3 (xx)
DE (1) DE60106968T2 (xx)
DO (1) DOP2001000289A (xx)
EA (1) EA200300432A1 (xx)
EC (1) ECSP034624A (xx)
EE (1) EE200300248A (xx)
ES (1) ES2230378T3 (xx)
HR (1) HRP20030420A2 (xx)
HU (1) HUP0302160A3 (xx)
IL (1) IL155704A0 (xx)
IS (1) IS6786A (xx)
MA (1) MA26964A1 (xx)
MX (1) MXPA03004870A (xx)
NO (1) NO20032441L (xx)
OA (1) OA12534A (xx)
PA (1) PA8534101A1 (xx)
PE (1) PE20020597A1 (xx)
PL (1) PL365927A1 (xx)
PT (1) PT1337271E (xx)
SK (1) SK6192003A3 (xx)
SV (1) SV2003000751A (xx)
TN (1) TNSN01169A1 (xx)
UY (1) UY27042A1 (xx)
WO (1) WO2002043762A2 (xx)
ZA (1) ZA200303381B (xx)

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Publication number Priority date Publication date Assignee Title
CN1094757C (zh) 1996-07-24 2002-11-27 沃尼尔·朗伯公司 用于治疗疼痛的异丁基γ－氨基丁酸及其衍生物
US6992109B1 (en) * 1999-04-08 2006-01-31 Segal Catherine A Method for the treatment of incontinence
US7022678B2 (en) * 2001-03-30 2006-04-04 Warner-Lambert Company Pregabalin lactose conjugates
JP2004534764A (ja) * 2001-05-25 2004-11-18 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 液状医薬組成物
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
KR20050036195A (ko) * 2003-10-15 2005-04-20 고재영 신규한 망막병증 치료제 조성물
BRPI0509399A (pt) * 2004-04-02 2007-09-18 Impax Laboratories Inc forma de dosagem farmacêutica
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
GB0420831D0 (en) 2004-09-17 2004-10-20 Glaxo Group Ltd Novel compounds
AU2006215080B2 (en) 2005-02-17 2011-03-10 Astellas Pharma Inc. Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative
GB0513553D0 (en) * 2005-07-01 2005-08-10 Fond D Amico Per La Ricerca Su Rab3a
JP5462784B2 (ja) 2007-04-27 2014-04-02 パーデュー、ファーマ、リミテッド、パートナーシップ Ｔｒｐｖ１アンタゴニストとその使用
WO2009046801A1 (en) * 2007-10-09 2009-04-16 Merck Patent Gmbh Pharmaceutical compositions containing benfotiamine and one or one more pharmaceutically active agents for the treatment of pain conditions of neuropathic origin
EP2116618A1 (en) 2008-05-09 2009-11-11 Agency for Science, Technology And Research Diagnosis and treatment of Kawasaki disease
CA2783699C (en) 2009-12-08 2019-01-15 Case Western Reserve University Primary amine compounds for treating ocular disorders
CN107050456B (zh) * 2010-09-28 2022-08-12 加利福尼亚大学董事会 治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合
PL2723732T3 (pl) 2011-06-22 2017-07-31 Purdue Pharma Lp Antagoniści trpv1 z podstawnikiem dihydroksylowym oraz ich zastosowania
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
WO2020212951A1 (en) 2019-04-17 2020-10-22 Compass Pathfinder Limited Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
CA3136100A1 (en) * 2019-05-07 2020-11-12 Stephan L. ZUCHNER Treatment and detection of inherited neuropathies and associated disorders

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US2409754A (en) 1946-10-22 Method for obtaining hydantoins
CH449645A (de) 1963-07-09 1968-01-15 Ciba Geigy Verfahren zur Herstellung neuer Aminosäuren
CH427803A (de) 1963-12-06 1967-01-15 Geigy Ag J R Verfahren zur Herstellung eines neuen Isoxazolderivates
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US3960927A (en) 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
FR2319338A1 (fr) * 1975-08-01 1977-02-25 Synthelabo Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent
GR68380B (xx) 1979-06-01 1981-12-28 Wellcome Found
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4513006A (en) 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
DK288385D0 (da) 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
US6197819B1 (en) 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
WO1994007867A1 (en) * 1992-09-28 1994-04-14 Pfizer Inc. Substituted pyrimidines for control of diabetic complications
AU3503300A (en) * 1999-02-24 2000-09-14 Regents Of The University Of California, The Gaba receptors mediate inhibition of t cell responses
CZ20013465A3 (cs) * 1999-04-01 2002-10-16 Pfizer Products Inc. Aminopyrimidiny jako inhibitory sorbitoldehydrogenasy
DE60009777T2 (de) * 1999-04-01 2004-08-19 Pfizer Products Inc., Groton Verbindung für Behandlung und Vorsorge bei Diabetes

Also Published As

Publication number Publication date
EE200300248A (et) 2003-10-15
CR6964A (es) 2004-02-02
DE60106968T2 (de) 2005-11-03
US6544998B2 (en) 2003-04-08
KR20030059290A (ko) 2003-07-07
SV2003000751A (es) 2003-01-13
ECSP034624A (es) 2003-07-25
AR031431A1 (es) 2003-09-24
AU2002215159A1 (en) 2002-06-11
SK6192003A3 (en) 2004-07-07
WO2002043762A3 (en) 2003-03-13
ZA200303381B (en) 2004-04-30
HUP0302160A2 (hu) 2003-11-28
DOP2001000289A (es) 2003-02-15
NO20032441L (no) 2003-07-03
NO20032441D0 (no) 2003-05-28
EP1337271B1 (en) 2004-11-03
PE20020597A1 (es) 2002-07-08
US20020091128A1 (en) 2002-07-11
AP2001002360A0 (en) 2001-12-31
HUP0302160A3 (en) 2005-05-30
WO2002043762A2 (en) 2002-06-06
EP1337271A2 (en) 2003-08-27
HRP20030420A2 (en) 2004-08-31
ES2230378T3 (es) 2005-05-01
CA2430298A1 (en) 2002-06-06
OA12534A (en) 2006-06-05
MA26964A1 (fr) 2004-12-20
BR0115783A (pt) 2003-09-16
DE60106968D1 (de) 2004-12-09
JP2004514699A (ja) 2004-05-20
CN1477975A (zh) 2004-02-25
MXPA03004870A (es) 2003-08-19
PT1337271E (pt) 2005-01-31
IL155704A0 (en) 2003-11-23
IS6786A (is) 2003-04-14
EA200300432A1 (ru) 2003-10-30
UY27042A1 (es) 2002-07-31
CZ20031399A3 (cs) 2004-04-14
TNSN01169A1 (fr) 2005-11-10
PA8534101A1 (es) 2002-10-31
PL365927A1 (en) 2005-01-10
ATE281181T1 (de) 2004-11-15

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