EE200000072A - Insuliini C-peptiidi rekombinantne ekspressioon - Google Patents

Insuliini C-peptiidi rekombinantne ekspressioon

Info

Publication number: EE200000072A
Authority: EE; Estonia
Prior art keywords: insulin; peptide; recombinant expression; recombinant; expression
Prior art date: 1997-08-07

Application number

EEP200000072A

Other languages

English (en)

Estonian (et)

Inventor

St�hl Stefan

Uhl�n Mathias

Nygren Per-Ke

Jonasson Per

Original Assignee

Creative Peptides Sweden Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-07

Filing date

1998-08-07

Publication date

2000-10-16

1998-08-07 Application filed by Creative Peptides Sweden Ab filed Critical Creative Peptides Sweden Ab

2000-10-16 Publication of EE200000072A publication Critical patent/EE200000072A/xx

Links

VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 VOUAQYXWVJDEQY-QENPJCQMSA-N 0.000 title 1
238000003259 recombinant expression Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Toxicology (AREA)
Obesity (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

EEP200000072A 1997-08-07 1998-08-07 Insuliini C-peptiidi rekombinantne ekspressioon EE200000072A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9716790.2A GB9716790D0 (en)	1997-08-07	1997-08-07	Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof
PCT/GB1998/002382 WO1999007735A2 (en)	1997-08-07	1998-08-07	Recombinant expression of insulin c-peptide

Publications (1)

Publication Number	Publication Date
EE200000072A true EE200000072A (et)	2000-10-16

Family

ID=10817184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000072A EE200000072A (et)	1997-08-07	1998-08-07	Insuliini C-peptiidi rekombinantne ekspressioon

Country Status (21)

Country	Link
US (1)	US6558924B1 (xx)
EP (1)	EP1001980A1 (xx)
JP (1)	JP2001512745A (xx)
KR (1)	KR20010022590A (xx)
CN (1)	CN1268141A (xx)
AU (1)	AU750685B2 (xx)
BG (1)	BG104161A (xx)
BR (1)	BR9811850A (xx)
CA (1)	CA2297382A1 (xx)
EA (1)	EA200000202A1 (xx)
EE (1)	EE200000072A (xx)
GB (1)	GB9716790D0 (xx)
HU (1)	HUP0004626A1 (xx)
IL (1)	IL134372A0 (xx)
IS (1)	IS5368A (xx)
NO (1)	NO20000575L (xx)
NZ (1)	NZ502450A (xx)
PL (1)	PL339085A1 (xx)
SK (1)	SK1532000A3 (xx)
TR (1)	TR200000288T2 (xx)
WO (1)	WO1999007735A2 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040005669A1 (en) *	1997-08-07	2004-01-08	Stefan Stahl	Recombinant expression of insulin C-peptide
FR2810675B1 (fr) *	2000-06-22	2002-09-27	Pf Medicament	Construction modifiee en aval du codon d'initiation pour la surexpression de proteines recombinantes
FR2810674A1 (fr) *	2000-06-22	2001-12-28	Pf Medicament	Construction modifiee en amont du codon d'initiation pour la surexpression de proteines recombinantes
CN100528235C (zh) *	2000-12-20	2009-08-19	霍夫曼-拉罗奇有限公司	红细胞生成素共轭物
JP2006503545A (ja) *	2002-02-14	2006-02-02	ラター，ウィリアムジェイ．	処置される宿主における切断についてのキメラ分子
WO2004047871A2 (en)	2002-11-26	2004-06-10	Nobex Corporation	Modified naturetic compounds, conjugates, and uses thereof
US20050026826A1 (en) *	2003-01-17	2005-02-03	Margarethe Hoenig	Feline proinsulin, insulin and constituent peptides
CN1298742C (zh) *	2003-06-03	2007-02-07	上海新药研究开发中心	一种适合于高效表达的融合蛋白及其生产方法
CN102504025B (zh) *	2004-03-10	2015-10-21	克赖顿大学	雌激素受体和使用方法
CA2798518A1 (en)	2010-05-17	2011-11-24	Cebix, Inc.	Pegylated c-peptide
EP2780030A4 (en)	2011-11-17	2015-11-18	Cebix Ab	PEGYLATED C-PEPTIDE
US20150315259A1 (en) *	2012-03-19	2015-11-05	Madeleine Phamaceuticals Pty Ltd	Method of producing a recombinant peptide
CA2979397A1 (en)	2015-03-12	2016-09-15	Board Of Trustees Of Michigan State University	Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases
CN109705221B (zh) *	2018-12-27	2021-03-09	美康生物科技股份有限公司	C肽免疫原及其单克隆抗体对及该抗体对在c肽磁微粒化学发光免疫试剂中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5210872B2 (xx)	1973-07-14	1977-03-26
GB2068971B (en)	1980-01-30	1983-06-08	Searle & Co	Recombinant dna techniques
CA1213537A (en)	1984-05-01	1986-11-04	Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee	Polypeptide expression method
US5013653A (en)	1987-03-20	1991-05-07	Creative Biomolecules, Inc.	Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
ATE113985T1 (de)	1987-03-20	1994-11-15	Creative Biomolecules Inc	Verfahren zur reinigung von rekombinanten polypeptiden.
SE501169C2 (sv)	1988-02-05	1994-11-28	Aake Nygren	Framställning av serumalbuminbindande fusionsproteiner vilka innehåller protein G-domäner
US5130236A (en)	1989-12-07	1992-07-14	Eli Lilly And Company	Process for producing des(64,65)-proinsulin
US5595887A (en)	1990-07-16	1997-01-21	Bionebraska, Inc.	Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
GB9015825D0 (en)	1990-07-18	1990-09-05	Ciba Geigy Ag	In vitro processing of fusion proteins
JPH07108232B2 (ja)	1990-10-09	1995-11-22	エム・ディ・リサーチ株式会社	ペプチド又は蛋白質の製造方法
US5953418A (en)	1995-06-14	1999-09-14	David Hall	Providing selective data broadcast receiver addressability
CA2213512A1 (en)	1995-12-22	1997-07-03	Toray Industries, Inc.	Method for producing bioactive fusion protein

1997
- 1997-08-07 GB GBGB9716790.2A patent/GB9716790D0/en active Pending
1998
- 1998-08-07 EP EP98937689A patent/EP1001980A1/en not_active Withdrawn
- 1998-08-07 PL PL98339085A patent/PL339085A1/xx not_active Application Discontinuation
- 1998-08-07 IL IL13437298A patent/IL134372A0/xx unknown
- 1998-08-07 WO PCT/GB1998/002382 patent/WO1999007735A2/en not_active Ceased
- 1998-08-07 AU AU86407/98A patent/AU750685B2/en not_active Ceased
- 1998-08-07 CA CA002297382A patent/CA2297382A1/en not_active Abandoned
- 1998-08-07 TR TR2000/00288T patent/TR200000288T2/xx unknown
- 1998-08-07 NZ NZ502450A patent/NZ502450A/xx unknown
- 1998-08-07 SK SK153-2000A patent/SK1532000A3/sk unknown
- 1998-08-07 CN CN98808075A patent/CN1268141A/zh active Pending
- 1998-08-07 EA EA200000202A patent/EA200000202A1/ru unknown
- 1998-08-07 HU HU0004626A patent/HUP0004626A1/hu unknown
- 1998-08-07 US US09/485,286 patent/US6558924B1/en not_active Expired - Fee Related
- 1998-08-07 KR KR1020007001182A patent/KR20010022590A/ko not_active Withdrawn
- 1998-08-07 EE EEP200000072A patent/EE200000072A/xx unknown
- 1998-08-07 BR BR9811850-1A patent/BR9811850A/pt not_active Application Discontinuation
- 1998-08-07 JP JP2000506237A patent/JP2001512745A/ja active Pending
2000
- 2000-02-01 IS IS5368A patent/IS5368A/is unknown
- 2000-02-04 NO NO20000575A patent/NO20000575L/no not_active Application Discontinuation
- 2000-02-17 BG BG104161A patent/BG104161A/xx unknown

Also Published As

Publication number	Publication date
AU8640798A (en)	1999-03-01
BR9811850A (pt)	2000-08-08
CN1268141A (zh)	2000-09-27
JP2001512745A (ja)	2001-08-28
NO20000575L (no)	2000-04-04
EP1001980A1 (en)	2000-05-24
GB9716790D0 (en)	1997-10-15
CA2297382A1 (en)	1999-02-18
AU750685B2 (en)	2002-07-25
SK1532000A3 (en)	2000-09-12
TR200000288T2 (tr)	2000-06-21
BG104161A (en)	2000-12-29
KR20010022590A (ko)	2001-03-26
NO20000575D0 (no)	2000-02-04
NZ502450A (en)	2002-10-25
IS5368A (is)	2000-02-01
IL134372A0 (en)	2001-04-30
EA200000202A1 (ru)	2001-04-23
WO1999007735A3 (en)	1999-04-29
WO1999007735A2 (en)	1999-02-18
US6558924B1 (en)	2003-05-06
PL339085A1 (en)	2000-12-04
HUP0004626A1 (hu)	2001-04-28

Publication	Publication Date	Title
NO2006014I1 (no)	2006-11-13	Insulin glulisin
NO2010013I1 (no)	2010-06-07	Rekombinant FSH-CTP
BR9510090A (pt)	1998-07-14	Utilização de um adenovírus recombinante
DK0884053T3 (da)	2002-11-04	Stabile insulinpræparater
DE69825982D1 (de)	2004-10-07	Spritze
FI972292A0 (fi)	1997-05-30	Administrering av diabetes
ATA101795A (de)	2001-06-15	Insulinanalogon-protamin-komplex
NO20002038D0 (no)	2000-04-18	Uløselig insulinsammensetning
IS5425A (is)	2000-03-31	Læknislyf
DK0963211T3 (da)	2005-05-30	Hypodermisk injektionssystem
DE69815881D1 (de)	2003-07-31	Nasaler dilatator
NO952357D0 (no)	1995-06-14	Formulering av insulinanaloger
ID27741A (id)	2001-04-26	Larutan teriparatide yang distabilkan
DE69822495D1 (de)	2004-04-22	Nadellose injektionsstelle
FI970132A7 (fi)	1997-02-11	Injektioruisku
DE69810382D1 (de)	2003-02-06	Spritzennadel
DE69812588D1 (de)	2003-04-30	Medizinischer injektor
EE200000072A (et)	2000-10-16	Insuliini C-peptiidi rekombinantne ekspressioon
NO976058L (no)	1998-02-03	Rekombinant mistellectin
DE69838308D1 (de)	2007-10-11	Langwelliger VCSEL
FI953001A0 (fi)	1995-06-16	Insuliinianalogeja
DE69917011D1 (de)	2004-06-09	Handgelenkprothese
ATE283706T1 (de)	2004-12-15	ßGEGEN RACEMISIERUNG STABILISIERTE PHARMAZEUTISCHE ZUBEREITUNGEN VON CILANSETRONß
DE69824327D1 (de)	2004-07-15	Inhalationsgerät
NO974924D0 (no)	1997-10-24	Modifiserte polypeptider med öket immunogenisitet