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ECSP12012100A - Composición de vacuna conjugada de polisacárido- proteína neumocócica 15-valente referencia cruzada a solicitudes relacionadas - Google Patents

Composición de vacuna conjugada de polisacárido- proteína neumocócica 15-valente referencia cruzada a solicitudes relacionadas

Info

Publication number
ECSP12012100A
ECSP12012100A ECSP12012100A ECSP12012100A EC SP12012100 A ECSP12012100 A EC SP12012100A EC SP12012100 A ECSP12012100 A EC SP12012100A EC SP12012100 A ECSP12012100 A EC SP12012100A
Authority
EC
Ecuador
Prior art keywords
protein
composition
polisacárido
pneumocócica
related applications
Prior art date
Application number
Other languages
English (en)
Inventor
Michael J Caulfield
Patrick L Ahl
Jeffrey T Blue
Jayme L Cannon
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of ECSP12012100A publication Critical patent/ECSP12012100A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención provee una composición inmunógena multivalente que tiene 15 conjugados de polisacáridos- proteína distintos. Cada conjugado consiste en un polisacárido capsular preparado a partir de un serotipo diferente de Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F o 33F) conjugado a una proteína portadora, preferentemente CRM197. La composición inmunógena, preferentemente formulada como una vacuna sobre un adyuvante a base de aluminio, proporciona una amplia cobertura contra la enfermedad neumocócica, particularmente en infantes y niños pequeños.
ECSP12012100 2010-02-09 2012-08-09 Composición de vacuna conjugada de polisacárido- proteína neumocócica 15-valente referencia cruzada a solicitudes relacionadas ECSP12012100A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30272610P 2010-02-09 2010-02-09

Publications (1)

Publication Number Publication Date
ECSP12012100A true ECSP12012100A (es) 2013-03-28

Family

ID=44353903

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP12012100 ECSP12012100A (es) 2010-02-09 2012-08-09 Composición de vacuna conjugada de polisacárido- proteína neumocócica 15-valente referencia cruzada a solicitudes relacionadas

Country Status (25)

Country Link
US (2) US8192746B2 (es)
EP (1) EP2533805A4 (es)
JP (2) JP2013518891A (es)
KR (1) KR101538535B1 (es)
CN (1) CN102858365A (es)
AR (2) AR080122A1 (es)
AU (1) AU2011216095B2 (es)
BR (1) BR112012019757B8 (es)
CA (1) CA2788680C (es)
CL (1) CL2012002195A1 (es)
EC (1) ECSP12012100A (es)
IL (1) IL221283A0 (es)
MA (1) MA34051B1 (es)
MX (1) MX2012009206A (es)
MY (1) MY159984A (es)
NZ (1) NZ601711A (es)
PE (1) PE20121698A1 (es)
PH (1) PH12012501559A1 (es)
RU (1) RU2012138368A (es)
SG (2) SG183199A1 (es)
TN (1) TN2012000377A1 (es)
TW (1) TW201136603A (es)
UA (1) UA106115C2 (es)
WO (1) WO2011100151A1 (es)
ZA (1) ZA201205737B (es)

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Also Published As

Publication number Publication date
SG183199A1 (en) 2012-09-27
AU2011216095A1 (en) 2012-08-09
CA2788680A1 (en) 2011-08-18
EP2533805A4 (en) 2013-08-28
US20120301502A1 (en) 2012-11-29
CL2012002195A1 (es) 2012-11-30
WO2011100151A1 (en) 2011-08-18
KR20120114345A (ko) 2012-10-16
BR112012019757B1 (pt) 2020-11-17
RU2012138368A (ru) 2014-03-20
PE20121698A1 (es) 2012-12-11
NZ601711A (en) 2014-03-28
TW201136603A (en) 2011-11-01
ZA201205737B (en) 2013-04-24
IL221283A0 (en) 2012-10-31
JP2014012720A (ja) 2014-01-23
MY159984A (en) 2017-02-15
KR101538535B1 (ko) 2015-07-22
US20110195086A1 (en) 2011-08-11
SG10201500350PA (en) 2015-03-30
MA34051B1 (fr) 2013-03-05
CA2788680C (en) 2014-12-16
MX2012009206A (es) 2012-08-23
AU2011216095B2 (en) 2013-07-18
AR080122A1 (es) 2012-03-14
CN102858365A (zh) 2013-01-02
EP2533805A1 (en) 2012-12-19
PH12012501559A1 (en) 2012-10-22
UA106115C2 (uk) 2014-07-25
US8192746B2 (en) 2012-06-05
AR116043A2 (es) 2021-03-25
TN2012000377A1 (en) 2014-01-30
BR112012019757A2 (pt) 2016-05-10
JP2013518891A (ja) 2013-05-23
BR112012019757B8 (pt) 2023-04-25

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