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DZ2086A1 - Benzylaminopipéridines substituées et compositionspharmaceutiques les contenant. - Google Patents

Benzylaminopipéridines substituées et compositionspharmaceutiques les contenant.

Info

Publication number
DZ2086A1
DZ2086A1 DZ960130A DZ960130A DZ2086A1 DZ 2086 A1 DZ2086 A1 DZ 2086A1 DZ 960130 A DZ960130 A DZ 960130A DZ 960130 A DZ960130 A DZ 960130A DZ 2086 A1 DZ2086 A1 DZ 2086A1
Authority
DZ
Algeria
Prior art keywords
benzylaminopiperidines
substituted
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
DZ960130A
Other languages
English (en)
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DZ2086A1 publication Critical patent/DZ2086A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DZ960130A 1995-08-24 1996-08-21 Benzylaminopipéridines substituées et compositionspharmaceutiques les contenant. DZ2086A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24

Publications (1)

Publication Number Publication Date
DZ2086A1 true DZ2086A1 (fr) 2002-07-22

Family

ID=11004362

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ960130A DZ2086A1 (fr) 1995-08-24 1996-08-21 Benzylaminopipéridines substituées et compositionspharmaceutiques les contenant.

Country Status (41)

Country Link
US (1) US6506775B1 (fr)
EP (2) EP0861235B1 (fr)
JP (1) JP3084069B2 (fr)
KR (1) KR100288673B1 (fr)
CN (1) CN1153764C (fr)
AP (1) AP643A (fr)
AR (1) AR006305A1 (fr)
AT (2) ATE258166T1 (fr)
AU (1) AU702698B2 (fr)
BG (1) BG64126B1 (fr)
BR (1) BR9609989A (fr)
CA (1) CA2227814C (fr)
CO (1) CO4480738A1 (fr)
CZ (1) CZ297543B6 (fr)
DE (2) DE69631390T2 (fr)
DK (2) DK1114817T3 (fr)
DZ (1) DZ2086A1 (fr)
ES (2) ES2163017T3 (fr)
HR (1) HRP960386B1 (fr)
HU (1) HU225480B1 (fr)
IL (1) IL119078A (fr)
IS (1) IS1947B (fr)
MA (1) MA23961A1 (fr)
MX (1) MX9801467A (fr)
MY (1) MY114800A (fr)
NO (1) NO310720B1 (fr)
NZ (1) NZ308207A (fr)
OA (1) OA10666A (fr)
PE (2) PE1398A1 (fr)
PL (1) PL186773B1 (fr)
PT (2) PT861235E (fr)
RO (1) RO119299B1 (fr)
RU (1) RU2152930C2 (fr)
SI (2) SI0861235T1 (fr)
SK (1) SK282925B6 (fr)
TN (1) TNSN96107A1 (fr)
TR (1) TR199800300T1 (fr)
TW (1) TW340842B (fr)
UA (1) UA48981C2 (fr)
WO (1) WO1997008144A1 (fr)
YU (1) YU49122B (fr)

Families Citing this family (59)

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MX9706196A (es) * 1996-08-14 1998-02-28 Pfizer Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p.
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en) 1999-02-10 2004-08-17 Eli Lilly And Company 5-HT1f agonist
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CA2374643C (fr) * 1999-05-21 2006-02-14 Pfizer Products Inc. Derives 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchromane en tant qu'antagonistes de la substance p
DK1095939T3 (da) * 1999-10-18 2004-04-13 Pfizer Prod Inc Fremgangsmåde til fremstilling af cykliske piperidinylaminomethyltrifluormethyletherforbindelser
CA2324116A1 (fr) * 1999-10-25 2001-04-25 Susan Beth Sobolov-Jaynes Antagonistes du recepteur nk-1 et eletriptan pour le traitement de la migraine
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
KR100885986B1 (ko) 1999-11-03 2009-03-03 에이엠알 테크놀로지, 인크. 노르에피네프린, 도파민 및 세로토닌의 재흡수를 방지하기위한 아릴 및 헤테로아릴 치환된테트라하이드로이소퀴놀린 및 이들의 용도
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
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US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (fr) * 2000-09-28 2003-03-26 Pfizer Products Inc. Composition pour le traitement de la dépression et de l'anxieté contenant un antagoniste du recepteur NK-3 et un antagoniste du récepteur NK-1
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
ES2388547T3 (es) 2003-04-18 2012-10-16 Eli Lilly And Company Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas de 5-HT 1F
CA2566920A1 (fr) * 2004-05-21 2005-12-01 Pfizer Products Inc. Metabolites de (+)-(2s, 3s)-3-(2-methoxy-5-trifluoromethoxybenzylamino)-2-phenyl-piperidine
AU2005274927B2 (en) 2004-07-15 2011-11-03 Albany Molecular Research, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ES2382814T3 (es) 2005-05-17 2012-06-13 Merck Sharp & Dohme Ltd. Ácido cis-4-[(4-clorofenil)sulfonil]-4-(2,5-difluorofenil)ciclohexanopropanoico para el tratamiento del cáncer
US7956050B2 (en) 2005-07-15 2011-06-07 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AU2006297443B2 (en) 2005-09-29 2010-08-12 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
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JP5319518B2 (ja) 2007-04-02 2013-10-16 Msd株式会社 インドールジオン誘導体
EP3103791B1 (fr) 2007-06-27 2018-01-31 Merck Sharp & Dohme Corp. Dérivés de 4-carboxybenzylamino utilisés comme inhibiteurs de l'histone désacétylase
EP2247185B1 (fr) 2008-03-03 2014-04-16 Tiger Pharmatech Inhibiteurs de la tyrosine kinase
EP2264029A4 (fr) 2008-03-31 2011-08-24 Kowa Co Dérivé de 1,3-dihydroisobenzofurane
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
US9034899B2 (en) 2009-05-12 2015-05-19 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
JP5739415B2 (ja) 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー (S)−7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンの結晶形態およびその使用
JP5764553B2 (ja) 2009-05-12 2015-08-19 アルバニー モレキュラー リサーチ, インコーポレイテッド 7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンおよびその使用
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US8999957B2 (en) 2010-06-24 2015-04-07 Merck Sharp & Dohme Corp. Heterocyclic compounds as ERK inhibitors
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WO2012027236A1 (fr) 2010-08-23 2012-03-01 Schering Corporation Nouveaux dérivés de pyrazolo[1,5-a]pyrimidine utilisés comme inhibiteurs de mtor
EP2613782B1 (fr) 2010-09-01 2016-11-02 Merck Sharp & Dohme Corp. Dérivés d'indazole utilisables en tant qu'inhibiteurs de la voie erk
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US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
RU2105001C1 (ru) * 1991-03-26 1998-02-20 Пфайзер Инк. Способ получения замещенных 3-аминопиперидинов
RU2114848C1 (ru) * 1991-06-20 1998-07-10 Пфайзер Инк. Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ ингибирования действия вещества р у млекопитающих
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EP0653208A3 (fr) * 1993-11-17 1995-10-11 Pfizer Antagonistes de la substance P pour le traitement et la prévention de l'erythème solaire.
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JP3992733B2 (ja) 1995-03-27 2007-10-17 久光製薬株式会社 ピペリジン誘導体
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US5990125A (en) 1996-01-19 1999-11-23 Pfizer Inc. NK-1 receptor antagonists for the treatment of cancer

Also Published As

Publication number Publication date
SK282925B6 (sk) 2003-01-09
CZ52198A3 (cs) 1999-01-13
KR19990044077A (ko) 1999-06-25
JP3084069B2 (ja) 2000-09-04
DE69631390D1 (de) 2004-02-26
HU225480B1 (en) 2006-12-28
RU2152930C2 (ru) 2000-07-20
KR100288673B1 (ko) 2001-05-02
DE69616817D1 (de) 2001-12-13
IL119078A (en) 2003-11-23
SK20798A3 (en) 1999-03-12
PL325332A1 (en) 1998-07-20
DE69616817T2 (de) 2002-04-04
BG64126B1 (bg) 2004-01-30
MX9801467A (es) 1998-05-31
OA10666A (en) 2002-11-25
EP1114817B1 (fr) 2004-01-21
DK0861235T3 (da) 2001-12-27
AP9600850A0 (en) 1996-10-31
IS4644A (is) 1997-12-30
HRP960386A2 (en) 1998-04-30
NO980751L (no) 1998-02-23
ES2211684T3 (es) 2004-07-16
HRP960386B1 (en) 2002-04-30
AU702698B2 (en) 1999-03-04
CA2227814A1 (fr) 1997-03-06
SI0861235T1 (en) 2002-04-30
WO1997008144A1 (fr) 1997-03-06
TW340842B (en) 1998-09-21
NZ308207A (en) 1998-07-28
YU47896A (sh) 1998-12-23
ATE258166T1 (de) 2004-02-15
CN1153764C (zh) 2004-06-16
TR199800300T1 (xx) 1998-06-22
ATE208377T1 (de) 2001-11-15
CO4480738A1 (es) 1997-07-09
PE20010700A1 (es) 2001-07-09
HUP9901159A2 (hu) 1999-07-28
NO310720B1 (no) 2001-08-20
TNSN96107A1 (fr) 2005-03-15
HUP9901159A3 (en) 2000-05-29
CN1193961A (zh) 1998-09-23
BR9609989A (pt) 1999-07-06
DK1114817T3 (da) 2004-04-26
PT861235E (pt) 2002-03-28
IL119078A0 (en) 1996-11-14
JPH10510554A (ja) 1998-10-13
EP0861235B1 (fr) 2001-11-07
RO119299B1 (ro) 2004-07-30
SI1114817T1 (en) 2004-06-30
IS1947B (is) 2004-10-13
HK1014935A1 (en) 1999-10-08
AR006305A1 (es) 1999-08-25
CZ297543B6 (cs) 2007-02-07
EP1114817A1 (fr) 2001-07-11
PE1398A1 (es) 1998-02-27
ES2163017T3 (es) 2002-01-16
PL186773B1 (pl) 2004-02-27
EP0861235A1 (fr) 1998-09-02
MA23961A1 (fr) 1997-04-01
UA48981C2 (uk) 2002-09-16
US6506775B1 (en) 2003-01-14
MY114800A (en) 2003-01-31
CA2227814C (fr) 2002-12-31
AP643A (en) 1998-04-24
NO980751D0 (no) 1998-02-23
PT1114817E (pt) 2004-05-31
AU5776996A (en) 1997-03-19
BG102288A (en) 1998-09-30
DE69631390T2 (de) 2004-11-25
YU49122B (sh) 2004-03-12

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