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ATE258166T1 - Substituierte benzylaminpiperidin-verbindungen - Google Patents

Substituierte benzylaminpiperidin-verbindungen

Info

Publication number
ATE258166T1
ATE258166T1 AT01108350T AT01108350T ATE258166T1 AT E258166 T1 ATE258166 T1 AT E258166T1 AT 01108350 T AT01108350 T AT 01108350T AT 01108350 T AT01108350 T AT 01108350T AT E258166 T1 ATE258166 T1 AT E258166T1
Authority
AT
Austria
Prior art keywords
benzylaminpiperidine
substituted
compounds
substituted benzylaminpiperidine
benzylaminpiperidine compounds
Prior art date
Application number
AT01108350T
Other languages
English (en)
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE258166T1 publication Critical patent/ATE258166T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01108350T 1995-08-24 1996-06-10 Substituierte benzylaminpiperidin-verbindungen ATE258166T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24

Publications (1)

Publication Number Publication Date
ATE258166T1 true ATE258166T1 (de) 2004-02-15

Family

ID=11004362

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01108350T ATE258166T1 (de) 1995-08-24 1996-06-10 Substituierte benzylaminpiperidin-verbindungen
AT96914375T ATE208377T1 (de) 1995-08-24 1996-06-10 Substituierte benzylaminopiperloin verbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT96914375T ATE208377T1 (de) 1995-08-24 1996-06-10 Substituierte benzylaminopiperloin verbindungen

Country Status (41)

Country Link
US (1) US6506775B1 (de)
EP (2) EP0861235B1 (de)
JP (1) JP3084069B2 (de)
KR (1) KR100288673B1 (de)
CN (1) CN1153764C (de)
AP (1) AP643A (de)
AR (1) AR006305A1 (de)
AT (2) ATE258166T1 (de)
AU (1) AU702698B2 (de)
BG (1) BG64126B1 (de)
BR (1) BR9609989A (de)
CA (1) CA2227814C (de)
CO (1) CO4480738A1 (de)
CZ (1) CZ297543B6 (de)
DE (2) DE69631390T2 (de)
DK (2) DK1114817T3 (de)
DZ (1) DZ2086A1 (de)
ES (2) ES2163017T3 (de)
HR (1) HRP960386B1 (de)
HU (1) HU225480B1 (de)
IL (1) IL119078A (de)
IS (1) IS1947B (de)
MA (1) MA23961A1 (de)
MX (1) MX9801467A (de)
MY (1) MY114800A (de)
NO (1) NO310720B1 (de)
NZ (1) NZ308207A (de)
OA (1) OA10666A (de)
PE (2) PE1398A1 (de)
PL (1) PL186773B1 (de)
PT (2) PT861235E (de)
RO (1) RO119299B1 (de)
RU (1) RU2152930C2 (de)
SI (2) SI0861235T1 (de)
SK (1) SK282925B6 (de)
TN (1) TNSN96107A1 (de)
TR (1) TR199800300T1 (de)
TW (1) TW340842B (de)
UA (1) UA48981C2 (de)
WO (1) WO1997008144A1 (de)
YU (1) YU49122B (de)

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TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en) 1999-02-10 2004-08-17 Eli Lilly And Company 5-HT1f agonist
IL145945A0 (en) * 1999-05-06 2002-07-25 Pfizer Prod Inc Substituted benzolactam compounds
RS49964B (sr) 1999-05-17 2008-09-29 Pfizer Products Inc., Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
CA2374643C (en) * 1999-05-21 2006-02-14 Pfizer Products Inc. 1-trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives as substance p antagonists
DK1095939T3 (da) * 1999-10-18 2004-04-13 Pfizer Prod Inc Fremgangsmåde til fremstilling af cykliske piperidinylaminomethyltrifluormethyletherforbindelser
CA2324116A1 (en) * 1999-10-25 2001-04-25 Susan Beth Sobolov-Jaynes Nk-1 receptor antagonists and eletriptan for the treatment of migraine
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
KR100885986B1 (ko) 1999-11-03 2009-03-03 에이엠알 테크놀로지, 인크. 노르에피네프린, 도파민 및 세로토닌의 재흡수를 방지하기위한 아릴 및 헤테로아릴 치환된테트라하이드로이소퀴놀린 및 이들의 용도
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
PA8525601A1 (es) * 2000-08-21 2002-04-25 Hoffmann La Roche Profarmacos de (3s,4s)-4-bencil-1-[2-(4-hidroxi-bencenosulfonil)-etil]-piperidin-3-ol
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (de) * 2000-09-28 2003-03-26 Pfizer Products Inc. Ein NK-3 rezeptorantagonisten und ein ZNS-penetrierende NK-1 rezeptorantagonisten enthaltende Zusammensetzung zur Behandlung von Depression und Angst
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
ES2388547T3 (es) 2003-04-18 2012-10-16 Eli Lilly And Company Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas de 5-HT 1F
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AU2005274927B2 (en) 2004-07-15 2011-11-03 Albany Molecular Research, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
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US7956050B2 (en) 2005-07-15 2011-06-07 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AU2006297443B2 (en) 2005-09-29 2010-08-12 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
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US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
EP2805945B1 (de) 2007-01-10 2019-04-03 MSD Italia S.r.l. Amidsubstituierte Indazole als Poly-(ADP-Ribose)-Polymerase (PARP)-Hemmer
JP5319518B2 (ja) 2007-04-02 2013-10-16 Msd株式会社 インドールジオン誘導体
EP3103791B1 (de) 2007-06-27 2018-01-31 Merck Sharp & Dohme Corp. 4-carboxybenzylamino-derivate als histondeacetylase-hemmer
EP2247185B1 (de) 2008-03-03 2014-04-16 Tiger Pharmatech Tyrosinkinase-hemmer
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US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
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JP5739415B2 (ja) 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー (S)−7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンの結晶形態およびその使用
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US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
RU2105001C1 (ru) * 1991-03-26 1998-02-20 Пфайзер Инк. Способ получения замещенных 3-аминопиперидинов
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US5990125A (en) 1996-01-19 1999-11-23 Pfizer Inc. NK-1 receptor antagonists for the treatment of cancer

Also Published As

Publication number Publication date
SK282925B6 (sk) 2003-01-09
CZ52198A3 (cs) 1999-01-13
KR19990044077A (ko) 1999-06-25
JP3084069B2 (ja) 2000-09-04
DE69631390D1 (de) 2004-02-26
HU225480B1 (en) 2006-12-28
RU2152930C2 (ru) 2000-07-20
KR100288673B1 (ko) 2001-05-02
DE69616817D1 (de) 2001-12-13
IL119078A (en) 2003-11-23
SK20798A3 (en) 1999-03-12
PL325332A1 (en) 1998-07-20
DE69616817T2 (de) 2002-04-04
BG64126B1 (bg) 2004-01-30
MX9801467A (es) 1998-05-31
OA10666A (en) 2002-11-25
EP1114817B1 (de) 2004-01-21
DK0861235T3 (da) 2001-12-27
AP9600850A0 (en) 1996-10-31
IS4644A (is) 1997-12-30
HRP960386A2 (en) 1998-04-30
NO980751L (no) 1998-02-23
ES2211684T3 (es) 2004-07-16
HRP960386B1 (en) 2002-04-30
AU702698B2 (en) 1999-03-04
CA2227814A1 (en) 1997-03-06
SI0861235T1 (en) 2002-04-30
WO1997008144A1 (en) 1997-03-06
TW340842B (en) 1998-09-21
NZ308207A (en) 1998-07-28
YU47896A (sh) 1998-12-23
CN1153764C (zh) 2004-06-16
TR199800300T1 (xx) 1998-06-22
ATE208377T1 (de) 2001-11-15
CO4480738A1 (es) 1997-07-09
PE20010700A1 (es) 2001-07-09
DZ2086A1 (fr) 2002-07-22
HUP9901159A2 (hu) 1999-07-28
NO310720B1 (no) 2001-08-20
TNSN96107A1 (fr) 2005-03-15
HUP9901159A3 (en) 2000-05-29
CN1193961A (zh) 1998-09-23
BR9609989A (pt) 1999-07-06
DK1114817T3 (da) 2004-04-26
PT861235E (pt) 2002-03-28
IL119078A0 (en) 1996-11-14
JPH10510554A (ja) 1998-10-13
EP0861235B1 (de) 2001-11-07
RO119299B1 (ro) 2004-07-30
SI1114817T1 (en) 2004-06-30
IS1947B (is) 2004-10-13
HK1014935A1 (en) 1999-10-08
AR006305A1 (es) 1999-08-25
CZ297543B6 (cs) 2007-02-07
EP1114817A1 (de) 2001-07-11
PE1398A1 (es) 1998-02-27
ES2163017T3 (es) 2002-01-16
PL186773B1 (pl) 2004-02-27
EP0861235A1 (de) 1998-09-02
MA23961A1 (fr) 1997-04-01
UA48981C2 (uk) 2002-09-16
US6506775B1 (en) 2003-01-14
MY114800A (en) 2003-01-31
CA2227814C (en) 2002-12-31
AP643A (en) 1998-04-24
NO980751D0 (no) 1998-02-23
PT1114817E (pt) 2004-05-31
AU5776996A (en) 1997-03-19
BG102288A (en) 1998-09-30
DE69631390T2 (de) 2004-11-25
YU49122B (sh) 2004-03-12

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