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DK573384A - Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater - Google Patents

Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater Download PDF

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Publication number
DK573384A
DK573384A DK573384A DK573384A DK573384A DK 573384 A DK573384 A DK 573384A DK 573384 A DK573384 A DK 573384A DK 573384 A DK573384 A DK 573384A DK 573384 A DK573384 A DK 573384A
Authority
DK
Denmark
Prior art keywords
derivatives
sphingosin
procedures
preparation
pharmaceutical compositions
Prior art date
Application number
DK573384A
Other languages
English (en)
Other versions
DK573384D0 (da
Inventor
Roland Tschannen
Wolfgang Fraefel
Richard Robert Schmidt
Rudolf Klaeger
Peter Zimmermann
Original Assignee
Solco Basel Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH6493/83A external-priority patent/CH679209A5/de
Application filed by Solco Basel Ag filed Critical Solco Basel Ag
Publication of DK573384D0 publication Critical patent/DK573384D0/da
Publication of DK573384A publication Critical patent/DK573384A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK573384A 1983-12-05 1984-12-03 Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater DK573384A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH6493/83A CH679209A5 (en) 1983-12-05 1983-12-05 New neutral glyco-sphingolipid derivs.
CH467184 1984-09-28

Publications (2)

Publication Number Publication Date
DK573384D0 DK573384D0 (da) 1984-12-03
DK573384A true DK573384A (da) 1985-06-06

Family

ID=25696036

Family Applications (1)

Application Number Title Priority Date Filing Date
DK573384A DK573384A (da) 1983-12-05 1984-12-03 Sphingosinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse derivater

Country Status (11)

Country Link
US (1) US4952683A (da)
EP (1) EP0146810A3 (da)
AU (1) AU570087B2 (da)
CA (1) CA1259610A (da)
DK (1) DK573384A (da)
ES (2) ES8604986A1 (da)
FI (1) FI844775L (da)
HU (1) HU195516B (da)
NO (1) NO844815L (da)
PL (1) PL143901B1 (da)
YU (2) YU202784A (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
EP0212400B1 (de) * 1985-08-13 1992-01-02 Solco Basel AG Neues Verfahren zur Herstellung von Sphingosinderivaten
US4769362A (en) * 1985-10-01 1988-09-06 Trustees Of Boston University Increased vascular perfusion following administration of lipids
JPH07116209B2 (ja) * 1986-04-11 1995-12-13 メクト株式会社 シアロシルセラミド類及びその製造方法
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
EP0299201A3 (de) * 1987-06-12 1990-08-22 Wilhelm Dr. Hoerrmann Fett-Aminoalkohol enthaltendes Arzneimittel
US5010059A (en) * 1987-06-26 1991-04-23 Solco Basel Ag Pharmaceutical products and lactosyl compounds
US4957741A (en) * 1988-08-02 1990-09-18 Angio-Medical Corp. Method for the treatment of gastric ulcer
US5066496A (en) * 1988-08-03 1991-11-19 Angio-Medical Corporation Composition and method for treatment of gastric and duodenal ulcers and mucosal erosions
IT1235162B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisosfingolipidi
DE3916072A1 (de) * 1989-05-17 1990-11-22 Thera Ges Fuer Patente Ceramidderivate und ihre verwendung als inhibitoren der sphingolipidsynthese
DE4102817A1 (de) * 1991-01-31 1992-08-06 Merck Patent Gmbh Verfahren zur stereoselektiven herstellung von (beta)-fucopyranosyl-phosphaten und sehr reiner gdp-fucose
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (da) * 1992-07-16 1995-11-01 Kirin Brewery
WO1994009020A1 (fr) * 1992-10-22 1994-04-28 Kirin Beer Kabushiki Kaisha Nouveau shingoglycolipide et son utilisation
CN1045302C (zh) * 1993-04-15 1999-09-29 麒麟麦酒株式会社 新型(神经)鞘糖脂、含有它们的药物组合物及其用途
WO1995003028A1 (en) * 1993-07-23 1995-02-02 Morris Herstein Cosmetic, skin-renewal stimulating composition with long-term irritation control
CA2142153A1 (en) * 1994-03-04 1995-09-05 Jacques Banville Sulfated .beta.-glycolipid derivatives as cell adhesion inhibitors
US5663151A (en) * 1994-03-04 1997-09-02 Bristol-Myers Squibb Company Sulfated α-glycolipid derivatives as cell adhesion inhibitors
US5686426A (en) * 1994-11-17 1997-11-11 Bristol-Myers Squibb Company Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors
JPH10501554A (ja) * 1995-02-03 1998-02-10 コリア インスティテュート オブ サイエンス アンド テクノロジー 新規な止血剤組成物
DE69818133T2 (de) * 1997-03-03 2004-06-09 Sumitomo Chemical Co., Ltd. Herstellung von einer optisch-aktiven Sphingoid-Verbindung
US6503885B1 (en) 1998-09-21 2003-01-07 Otsuka Pharmaceutical Co., Ltd. Carboxymethylgalactose derivatives
US20040180852A1 (en) * 2003-03-10 2004-09-16 Cara-Lynne Schengrund Use of multivalent glycodendrimers to inhibit the activity of human immunodeficiency virus
DE102004025000A1 (de) * 2004-05-21 2005-12-08 Bayer Technology Services Gmbh Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie
CN101460458A (zh) 2006-02-15 2009-06-17 阿勒根公司 具有1－磷酸－鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚－3－羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物
WO2007112322A2 (en) * 2006-03-28 2007-10-04 Allergan, Inc. Indole compounds having sphingosine-1-phosphate (s1p) receptor agonist and/or antagonist biological activity
WO2008005824A1 (en) 2006-06-30 2008-01-10 The Scripps Research Institute Adjuvants and methods of use
US8524917B2 (en) * 2007-01-11 2013-09-03 Allergan, Inc. 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
KR20090101307A (ko) 2007-01-11 2009-09-24 알러간, 인코포레이티드 스핑고신-1-포스페이트(ｓ1ｐ) 수용체 길항제 생물학적 활성을 갖는 6-치환된 인돌-3-카르복실산 아미드 화합물
RU2010112275A (ru) * 2007-09-24 2011-11-10 Аллерган, Инк. (Us) Индольные соединения, содержащие арильные или гетероарильные группы, обладющие биологической активностью рецептора сфингозин-1-фосфата (с1ф)
US8143291B2 (en) 2008-05-09 2012-03-27 Allergan, Inc. Indole compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (S1P) receptor biological activity
KR20110044893A (ko) * 2008-08-12 2011-05-02 알러간, 인코포레이티드 스핑고신-1-포스페이트 (ｓ1ｐ) 수용체 길항제 및 이의 사용 방법
US20120088800A1 (en) 2009-06-30 2012-04-12 Allergan, Inc. 2-(SUBSTITUTED) (ARYLMETHYL, ARYLOXY and ARYLTHIO))-N-(SUBSTITUTED PYRIDIN-2-YL)-2-(SUBSTITUTED ARYL) COMPOUNDS AS SUBTYPE-SELECTIVE MODULATORS OF SPHINGOSINE-1-PHOSPHATE-3 (S1P3) RECEPTORS
US8168795B2 (en) * 2009-08-11 2012-05-01 Allergan, Inc. Selective sphingosine-1-phosphate receptor antagonists
WO2011028927A1 (en) 2009-09-04 2011-03-10 Allergan, Inc. Selective sphingosine-1-phosphate receptor antagonists
CN102741232A (zh) 2009-09-29 2012-10-17 阿勒根公司 作为鞘氨醇-1-磷酸酯-2(s1p2)受体的亚型-选择性调节剂的稠环吡啶化合物
US8741875B2 (en) 2009-11-24 2014-06-03 Allergan, Inc. Compounds as receptor modulators with therapeutic utility
MX2012006028A (es) * 2009-11-24 2012-06-19 Allergan Inc Compuestos novedosos como moduladores de receptor con utilidad terapeutica.
AU2011332069A1 (en) 2010-11-22 2013-07-04 Allergan, Inc. Novel compounds as receptor modulators with therapeutic utility
US9708354B2 (en) 2013-03-15 2017-07-18 Cerenis Therapeutics Holding Sa Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
EP2970344A2 (en) 2013-03-15 2016-01-20 Cerenis Therapeutics Holding SA Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
US20240132440A1 (en) 2021-01-25 2024-04-25 Carbocode S.A. Method for the production of d-erythro-sphingosine and analogs thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1495548A (en) * 1974-04-16 1977-12-21 Tate & Lyle Ltd Sugar derivative containing vinyl groups and copolymers thereof
US4362720A (en) * 1977-04-14 1982-12-07 Chembiomed Ltd. Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals

Also Published As

Publication number Publication date
EP0146810A3 (de) 1987-05-13
ES8606373A1 (es) 1986-04-16
AU3628684A (en) 1985-06-13
PL143901B1 (en) 1988-03-31
NO844815L (no) 1985-06-06
YU202784A (en) 1987-02-28
ES548901A0 (es) 1986-04-16
EP0146810A2 (de) 1985-07-03
HUT36833A (en) 1985-10-28
PL250710A1 (en) 1985-07-16
HU195516B (en) 1988-05-30
CA1259610A (en) 1989-09-19
ES538231A0 (es) 1986-03-16
FI844775A7 (fi) 1985-06-06
DK573384D0 (da) 1984-12-03
US4952683A (en) 1990-08-28
FI844775L (fi) 1985-06-06
FI844775A0 (fi) 1984-12-04
AU570087B2 (en) 1988-03-03
ES8604986A1 (es) 1986-03-16
YU189686A (en) 1987-12-31

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