DK426778A - Fremgans fremgangsmaade til fremstilling af 7-(d(-)-alfa-(4-ethyl-2,3-dioxo-1-piperazincarboxamido)-alfa(4-hydroxyphenyl)acetamido)-3-(5-(1-methyl-1,2,3,4-tetrazolyl)-thiomethyl)-delta3-cephemt -4-carboxylsyre eller farmaceutisk acceptable salte deraf sam - Google Patents

Fremgans fremgangsmaade til fremstilling af 7-(d(-)-alfa-(4-ethyl-2,3-dioxo-1-piperazincarboxamido)-alfa(4-hydroxyphenyl)acetamido)-3-(5-(1-methyl-1,2,3,4-tetrazolyl)-thiomethyl)-delta3-cephemt -4-carboxylsyre eller farmaceutisk acceptable salte deraf sam

Info

Publication number: DK426778A
Authority: DK; Denmark
Prior art keywords: alfa; piperazincarboxamido; cephemt; delta3; thiomethyl
Prior art date: 1977-09-27

Application number

DK426778A

Other languages

English (en)

Other versions

DK164705C (da

DK164705B (da

Inventor

I Saikawa

S Takano

K Momonoi

I Takakura

Til Anvendelse D Mellemprodukt

C Kutani

K Tanaka

Af Mellemprodukt Mstilling

K Hayashi

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-09-27

Filing date

1978-09-26

Publication date

1979-03-28

1977-09-27 Priority claimed from JP52115127A external-priority patent/JPS6056718B2/ja

1977-09-27 Priority claimed from JP52115126A external-priority patent/JPS6056717B2/ja

1978-09-26 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

1979-03-28 Publication of DK426778A publication Critical patent/DK426778A/da

1992-08-03 Publication of DK164705B publication Critical patent/DK164705B/da

1992-12-21 Application granted granted Critical

1992-12-21 Publication of DK164705C publication Critical patent/DK164705C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)

DK426778A 1977-09-27 1978-09-26 Fremgangsmaade til fremstilling af 7-oed(-)-alfa-(4-ethyl-2,3-dioxo-1-piperazincarboxamido)-alfa-(4-hydroxyphenyl)acetamidoaa-3-oe5-(1-methyl-1,2,3,4-tetrazolyl)-thiomethylaa-delta3-cephem-4-carboxylsyre eller farmaceutisk acceptable salte deraf DK164705C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP11512677		1977-09-27
JP11512777		1977-09-27
JP52115127A JPS6056718B2 (ja)	1977-09-27	1977-09-27	セフアロスポリンの製法
JP52115126A JPS6056717B2 (ja)	1977-09-27	1977-09-27	セフアロスポリンのｎ，ｎ−ジメチルアセトアミド付加体及びその製法

Publications (3)

Publication Number	Publication Date
DK426778A true DK426778A (da)	1979-03-28
DK164705B DK164705B (da)	1992-08-03
DK164705C DK164705C (da)	1992-12-21

Family

ID=26453712

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK426778A DK164705C (da)	1977-09-27	1978-09-26	Fremgangsmaade til fremstilling af 7-oed(-)-alfa-(4-ethyl-2,3-dioxo-1-piperazincarboxamido)-alfa-(4-hydroxyphenyl)acetamidoaa-3-oe5-(1-methyl-1,2,3,4-tetrazolyl)-thiomethylaa-delta3-cephem-4-carboxylsyre eller farmaceutisk acceptable salte deraf
DK197391A DK164405C (da)	1977-09-27	1991-12-06	N,n-dimethylacetamid-additionsprodukt af cephalosporin og fremgangsmaade til fremstilling deraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK197391A DK164405C (da)	1977-09-27	1991-12-06	N,n-dimethylacetamid-additionsprodukt af cephalosporin og fremgangsmaade til fremstilling deraf

Country Status (20)

Country	Link
US (2)	US4237280A (da)
AR (1)	AR223653A1 (da)
AT (1)	AT362502B (da)
AU (1)	AU513336B2 (da)
CA (1)	CA1102309A (da)
CH (1)	CH637967A5 (da)
DD (1)	DD141835A5 (da)
DE (1)	DE2841706C2 (da)
DK (2)	DK164705C (da)
ES (1)	ES473692A1 (da)
FI (1)	FI71743C (da)
FR (1)	FR2409270A1 (da)
GB (1)	GB2005676B (da)
HU (1)	HU177912B (da)
IL (1)	IL55607A (da)
IN (1)	IN149604B (da)
MX (1)	MX5571E (da)
NL (1)	NL7809736A (da)
PT (1)	PT68594A (da)
SE (2)	SE436360B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100388108B1 (ko) *	2000-08-11	2003-06-18	주식회사종근당	세팔로스포린계 항생제 중간체 신규 제조방법
CN102532168A (zh) *	2011-12-27	2012-07-04	山东鑫泉医药有限公司	头孢哌酮酸的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3641021A (en) *	1969-04-18	1972-02-08	Lilly Co Eli	3 7-(ring-substituted) cephalosporin compounds
US3714157A (en) *	1970-10-23	1973-01-30	Bristol Myers Co	PROCESS FOR THE DECOLORIZATION OF 7-[ alpha -(4-PYRIDYLTHIO)ACETAMIDO]CEPHALOSPORANIC ACID
US3781282A (en) *	1971-01-20	1973-12-25	W Garbrecht	Cephalosporin process and product
US4112090A (en) *	1974-05-09	1978-09-05	Toyama Chemical Co., Ltd.	Novel penicillins and cephalosporins and process for producing the same
US3954745A (en) *	1974-09-12	1976-05-04	Eli Lilly And Company	Process for preparing cefazolin
US4117126A (en) *	1975-04-03	1978-09-26	Sumitomo Chemical Company, Ltd.	7-(α-(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-α-phenylacetamido) cephalosporin derivatives
US4037922A (en) *	1975-07-07	1977-07-26	Corning Glass Works	Optical waveguide cable
US4064345A (en) *	1975-12-12	1977-12-20	Bristol-Myers Company	Cephalosporins derivatives 7-cyclized α-amino-3-heterothio
US4145418A (en) *	1976-01-06	1979-03-20	Takeda Chemical Industries, Ltd.	Thienopyridine substituted cephalosporins
US4103008A (en) *	1976-04-07	1978-07-25	Ishimaru Toshiyasu	7[2(2,3 Dioxopiperazin-1-yl-carbonylamino)substituted 2 phenylacetamido]-3-2'-thiadiazolyl cephalosporanic acid derivatives

1978
- 1978-06-26 AR AR273853A patent/AR223653A1/es active
- 1978-09-18 IN IN1020/CAL/78A patent/IN149604B/en unknown
- 1978-09-18 AU AU39923/78A patent/AU513336B2/en not_active Expired
- 1978-09-20 IL IL55607A patent/IL55607A/xx unknown
- 1978-09-22 FR FR7827249A patent/FR2409270A1/fr active Granted
- 1978-09-25 CH CH996678A patent/CH637967A5/fr not_active IP Right Cessation
- 1978-09-25 US US05/945,346 patent/US4237280A/en not_active Expired - Lifetime
- 1978-09-25 DD DD78208068A patent/DD141835A5/de not_active IP Right Cessation
- 1978-09-25 GB GB7838036A patent/GB2005676B/en not_active Expired
- 1978-09-25 FI FI782912A patent/FI71743C/fi not_active IP Right Cessation
- 1978-09-25 CA CA312,056A patent/CA1102309A/en not_active Expired
- 1978-09-25 DE DE2841706A patent/DE2841706C2/de not_active Expired
- 1978-09-26 ES ES473692A patent/ES473692A1/es not_active Expired
- 1978-09-26 SE SE7810106A patent/SE436360B/sv not_active IP Right Cessation
- 1978-09-26 HU HU78TO1098A patent/HU177912B/hu unknown
- 1978-09-26 AT AT693878A patent/AT362502B/de not_active IP Right Cessation
- 1978-09-26 NL NL7809736A patent/NL7809736A/xx active Search and Examination
- 1978-09-26 PT PT68594A patent/PT68594A/pt unknown
- 1978-09-26 DK DK426778A patent/DK164705C/da not_active IP Right Cessation
- 1978-09-27 MX MX787431U patent/MX5571E/es unknown
1979
- 1979-08-24 US US06/069,545 patent/US4304909A/en not_active Expired - Lifetime
1983
- 1983-11-11 SE SE8306226A patent/SE447732B/sv not_active IP Right Cessation
1991
- 1991-12-06 DK DK197391A patent/DK164405C/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
AT362502B (de)	1981-05-25
DK164705C (da)	1992-12-21
NL7809736A (nl)	1979-03-29
DD141835A5 (de)	1980-05-21
PT68594A (en)	1978-10-01
AU513336B2 (en)	1980-11-27
FR2409270B1 (da)	1983-01-14
US4304909A (en)	1981-12-08
SE7810106L (sv)	1979-03-28
DK164705B (da)	1992-08-03
HU177912B (en)	1982-01-28
IL55607A (en)	1981-10-30
AU3992378A (en)	1980-03-27
FI71743C (fi)	1987-02-09
DK164405C (da)	1992-11-16
ES473692A1 (es)	1979-12-16
ATA693878A (de)	1980-10-15
US4237280A (en)	1980-12-02
GB2005676B (en)	1982-06-23
IN149604B (da)	1982-02-13
DE2841706C2 (de)	1982-11-04
DK197391D0 (da)	1991-12-06
MX5571E (es)	1983-10-18
SE447732B (sv)	1986-12-08
DK197391A (da)	1991-12-06
SE436360B (sv)	1984-12-03
GB2005676A (en)	1979-04-25
SE8306226D0 (sv)	1983-11-11
DK164405B (da)	1992-06-22
CH637967A5 (fr)	1983-08-31
AR223653A1 (es)	1981-09-15
FR2409270A1 (fr)	1979-06-15
FI71743B (fi)	1986-10-31
SE8306226L (sv)	1983-11-11
DE2841706A1 (de)	1979-04-05
FI782912A7 (fi)	1979-03-28
CA1102309A (en)	1981-06-02

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Legal Events

Date	Code	Title	Description
1998-10-12	PUP	Patent expired