DK3251678T3 - Benzoxaborolderivater til behandling af bakterieinfektioner - Google Patents

Benzoxaborolderivater til behandling af bakterieinfektioner Download PDF

Info

Publication number: DK3251678T3
Authority: DK; Denmark
Prior art keywords: benzoxaborol; derivatives; treatment; bacteria infections; infections
Prior art date: 2010-09-07

Application number

DK17176654.6T

Other languages

English (en)

Inventor

Vincent S Hernandez

Charles Ding

Jacob J Plattner

Michael Richard Kevin Alley

Fernando Rock

Eric Easom

Xianfeng Li

Ding Zhou

Suoming Zhang

Original Assignee

Anacor Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-09-07

Filing date

2011-09-07

Publication date

2021-11-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44653589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3251678(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-09-07 Application filed by Anacor Pharmaceuticals Inc filed Critical Anacor Pharmaceuticals Inc

2021-11-22 Application granted granted Critical

2021-11-22 Publication of DK3251678T3 publication Critical patent/DK3251678T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK17176654.6T 2010-09-07 2011-09-07 Benzoxaborolderivater til behandling af bakterieinfektioner DK3251678T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US38059610P	2010-09-07	2010-09-07
EP11758050.6A EP2613788B1 (en)	2010-09-07	2011-09-07	Benzoxaborole derivatives for treating bacterial infections

Publications (1)

Publication Number	Publication Date
DK3251678T3 true DK3251678T3 (da)	2021-11-22

Family

ID=44653589

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK11758050.6T DK2613788T3 (da)	2010-09-07	2011-09-07	Benzoxaborolderivater til behandling af bakterieinfektioner
DK17176654.6T DK3251678T3 (da)	2010-09-07	2011-09-07	Benzoxaborolderivater til behandling af bakterieinfektioner

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK11758050.6T DK2613788T3 (da)	2010-09-07	2011-09-07	Benzoxaborolderivater til behandling af bakterieinfektioner

Country Status (25)

Country	Link
US (4)	US8703742B2 (da)
EP (2)	EP2613788B1 (da)
JP (4)	JP5952280B2 (da)
KR (2)	KR101949423B1 (da)
CN (2)	CN108610356B (da)
AU (1)	AU2011299243C1 (da)
BR (1)	BR112013005426B1 (da)
CA (1)	CA2810021C (da)
CY (1)	CY1124728T1 (da)
DK (2)	DK2613788T3 (da)
EA (2)	EA028743B1 (da)
ES (2)	ES2635333T3 (da)
HR (1)	HRP20211762T1 (da)
HU (1)	HUE059033T2 (da)
IL (2)	IL225000A (da)
LT (1)	LT3251678T (da)
MX (1)	MX338209B (da)
PL (1)	PL3251678T3 (da)
PT (1)	PT3251678T (da)
RS (1)	RS62548B1 (da)
SG (2)	SG187969A1 (da)
SI (1)	SI3251678T1 (da)
SM (1)	SMT202100643T1 (da)
WO (1)	WO2012033858A2 (da)
ZA (1)	ZA201301598B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN106008583A (zh)	2005-12-30	2016-10-12	安纳考尔医药公司	含硼的小分子
WO2011019618A1 (en)	2009-08-14	2011-02-17	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules as antiprotozoal agents
WO2011094450A1 (en)	2010-01-27	2011-08-04	Anacor Pharmaceuticals, Inc	Boron-containing small molecules
WO2012033858A2 (en) *	2010-09-07	2012-03-15	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
CN104136032B (zh)	2011-12-22	2018-11-13	盟科医药技术公司	可用于抗菌治疗的三环类硼化合物
US9585396B2 (en)	2013-01-30	2017-03-07	Agrofresh Inc.	Volatile applications against pathogens
AR094666A1 (es)	2013-01-30	2015-08-19	Dow Agrosciences Llc	Uso de benzoxaborolas como agentes antimicrobianos volátiles en carnes, plantas o partes de plantas
US8669207B1 (en)	2013-01-30	2014-03-11	Dow Agrosciences, Llc.	Compounds and compositions
US11039617B2 (en)	2013-01-30	2021-06-22	Agrofresh Inc.	Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US10070649B2 (en)	2013-01-30	2018-09-11	Agrofresh Inc.	Volatile applications against pathogens
WO2014121124A1 (en)	2013-02-01	2014-08-07	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules as antiprotozoal agents
KR101636431B1 (ko)	2013-07-30	2016-07-05	동아에스티 주식회사	트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
MY175823A (en) *	2013-08-09	2020-07-10	Glaxosmithkline Ip No 2 Ltd	Tricyclic benzoxaborole compounds and uses thereof
EA038093B1 (ru) *	2013-12-20	2021-07-05	Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед	Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли
EP3164404B1 (en) *	2014-07-01	2019-04-03	Daiichi Sankyo Company, Limited	Tricyclic benzoxaboroles as antibacterial agents
MA41494B1 (fr) *	2015-02-12	2020-10-28	Glaxosmithkline Ip No 2 Ltd	Composés benzoxaborole substitués en position 4 et utilisations associées
TW201735792A (zh)	2016-03-07	2017-10-16	農業保鮮股份有限公司	使用苯并氧雜硼雜環戊烯化合物和防腐氣體作為作物的抗微生物劑之協同方法
WO2018160845A1 (en)	2017-03-01	2018-09-07	Anacor Pharmaceuticals, Inc.	Novel oxaborole analogs and uses thereof
EP3716766A4 (en)	2017-11-30	2021-12-22	Boragen, Inc.	BENZOXABOROLE COMPOUNDS AND THEIR FORMULATIONS
CN108727176B (zh) *	2018-07-26	2021-05-18	荆楚理工学院	一种制备5-卤-2,3-二羟基苯甲醛的方法
EP3836938A4 (en)	2018-08-18	2022-05-11	Boragen, Inc.	SOLID FORMS OF SUBSTITUTED BENZOXAZOLE AND COMPOSITIONS THEREOF
AR119515A1 (es) *	2019-07-30	2021-12-22	Boragen Inc	Proceso de reacción de flujo para la fabricación de agroquímicos que contienen boro
CN110664756B (zh) *	2019-10-09	2020-11-17	吉林大学	一种小儿外伤喷雾剂及其制备方法
WO2022043936A1 (en)	2020-08-31	2022-03-03	Pfizer Inc.	Methods of protecting rna
AU2023287063A1 (en) *	2022-06-23	2024-05-30	Shanghai Micurx Pharmaceutical Co., Ltd.	Prodrugs of boron compounds and their use in treating bacterial infections
CN119233823A (zh) *	2022-06-23	2024-12-31	上海盟科药业股份有限公司	硼化合物治疗非结核分枝杆菌感染的方法和用途及用于治疗相同疾病的药物组合物
CN115572218B (zh) *	2022-08-29	2024-04-16	江阴勒森生物科技有限公司	一种2-溴-3-羟基苯甲醛及其相关化学发光底物中间体的制备方法

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2260336A (en)	1939-10-16	1941-10-28	Dow Chemical Co	Method of preparation of organic borates
US3686398A (en)	1970-07-20	1972-08-22	Chevron Res	10,9-boroxarophenanthrene as fungicides
GB1396904A (en)	1972-08-11	1975-06-11	Ici Ltd	Method for the control of micro-organisms
US4602011A (en)	1975-10-24	1986-07-22	Chapman Chemical Company	Antimicrobial compositions and methods of using same
US4766113A (en)	1975-10-24	1988-08-23	Chapman Chemical Company	Antimicrobial compositions and methods of using same
US4716035A (en)	1985-05-24	1987-12-29	The Procter & Gamble Company	Oral compositions and methods for treating gingivitis
US5962498A (en)	1986-06-11	1999-10-05	Procyon Pharmaceuticals, Inc.	Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US4894220A (en)	1987-01-30	1990-01-16	Colgate-Palmolive Company	Antibacterial antiplaque oral composition
US4919934A (en)	1989-03-02	1990-04-24	Richardson-Vicks Inc.	Cosmetic sticks
US5274792A (en)	1989-08-19	1993-12-28	Fujitsu Limited	Information processing apparatus with parallel instruction decoding
SG47101A1 (en)	1992-07-31	1998-03-20	Us Bioscience	Crystalline amifostine compositions and methods for the preparation and use of same
US5348948A (en)	1993-05-07	1994-09-20	American Cyanamid Company	2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal
US5348947A (en)	1993-05-07	1994-09-20	American Cyanamid Company	Diarylboron ester and thioester fungicidal agents
US5594151A (en)	1994-01-28	1997-01-14	Prolinx, Inc.	Phenylboronic acid complexing reagents derived from aminosalicylic acid
GB9411587D0 (en)	1994-06-09	1994-08-03	Zeneca Ltd	Compound, composition and use
US6083903A (en)	1994-10-28	2000-07-04	Leukosite, Inc.	Boronic ester and acid compounds, synthesis and uses
GB9500856D0 (en)	1995-01-17	1995-03-08	Zeneca Ltd	Composition and use
US6632955B1 (en)	1996-12-02	2003-10-14	Chisso Corporation	Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
GB9604926D0 (en)	1996-03-08	1996-05-08	Sandoz Ltd	Organic compounds
JP4373497B2 (ja)	1996-06-19	2009-11-25	ローン−プーラン・ロレ・リミテツド	置換されたアザビシクロ化合物、ならびにｔｎｆおよびサイクリックａｍｐホスホジエステラーゼ産生の阻害剤としてのそれらの使用
US5831046A (en)	1996-08-05	1998-11-03	Prolinx, Incorporated	Boronic acid-contaning nucleic acid monomers
AU4486097A (en)	1996-09-19	1998-04-14	Board Of Trustees Of The Leland Stanford Junior University	Dna adenine methyltransferases and uses thereof
US6221640B1 (en)	1997-05-14	2001-04-24	Cubist Pharmaceuticals, Inc.	Enterococcal aminoacyl-trna synthetase proteins, nucleic acids and strains comprising same
DE19829947A1 (de)	1998-07-04	2000-01-05	Bayer Ag	Elektrolumineszierende Anordnungen mit Bor-Chelaten
US6462036B1 (en)	1998-11-06	2002-10-08	Basf Aktiengesellschaft	Tricyclic pyrazole derivatives
WO2000027822A2 (en)	1998-11-06	2000-05-18	Basf Aktiengesellschaft	Tricyclic pyrazole derivatives
EP1155698A4 (en)	1999-01-29	2003-01-15	Nitto Kasei Co Ltd	ORGANOBORAL COMPOUNDS HAVING COCCIDIOSTAT ACTIVITY
JP2003501431A (ja)	1999-05-25	2003-01-14	ザペンステートリサーチファウンデイション	Ｄｎａメチル基転移酵素阻害剤
US6306628B1 (en)	1999-08-25	2001-10-23	Ambergen, Incorporated	Methods for the detection, analysis and isolation of Nascent proteins
DE60045879D1 (de)	1999-08-25	2011-06-01	Ambergen Inc	Methoden zur Detektion, Analyse und Isolation von entstehenden Proteinen
AU7995300A (en)	1999-10-05	2001-05-10	Bethesda Pharmaceuticals, Inc.	Dithiolane derivatives
WO2001049301A1 (en)	2000-01-06	2001-07-12	Marantech Holding, Llc	Methods of using electron active compounds for managing cancer
US6521619B2 (en)	2000-06-29	2003-02-18	Icos Corporation	Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents
AU2001275930B2 (en)	2000-07-14	2007-05-10	Eisai Inc.	Alpha-msh related compounds and methods of use
DE60124759T2 (de)	2000-11-30	2007-03-15	The Penn State Research Foundation	Dna methyl transferase inhibitoren
DE10110051C2 (de)	2001-03-02	2003-07-03	Clariant Gmbh	Verfahren zur Herstellung von Boron- und Borinsäuren
CA2446904A1 (en)	2001-05-24	2003-04-03	Alexza Molecular Delivery Corporation	Delivery of drug esters through an inhalation route
US7766013B2 (en)	2001-06-05	2010-08-03	Alexza Pharmaceuticals, Inc.	Aerosol generating method and device
GB0117645D0 (en)	2001-07-19	2001-09-12	Isis Innovation	Therapeutic stratergies for prevention and treatment of alzheimers disease
DE10143979A1 (de)	2001-09-07	2003-03-27	Clariant Gmbh	Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren
US7217701B2 (en)	2001-10-11	2007-05-15	Katsuhiko Mikoshiba	Intracellular calcium concentration increase inhibitors
US7405304B2 (en)	2002-01-10	2008-07-29	The Penn State Research Foundation	Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids
IL166156A0 (en)	2002-07-09	2006-01-15	Point Therapeutics Inc	Boroproline compound combination therapy
AU2003298328A1 (en)	2002-12-02	2004-06-23	Solvias Ag	Catalytic hydrogeneration of carbon-heteroatom double bonds
CA2509645A1 (en)	2002-12-18	2004-07-08	Anacor Pharmaceuticals, Inc.	Antibiotics containing borinic acid complexes and methods of use
US7390806B2 (en)	2002-12-18	2008-06-24	Anacor Pharmaceuticals, Inc.	Antibiotics containing borinic acid complexes and methods of use
US20050125852A1 (en)	2003-05-09	2005-06-09	Sugen, Inc.	Novel kinases
US7465836B2 (en)	2003-06-16	2008-12-16	Anacor Pharmaceuticals, Inc.	Hydrolytically-resistant boron-containing therapeutics and methods of use
EP2335722B1 (en)	2004-05-12	2019-03-13	The Brigham and Women's Hospital, Inc.	Use of gelsolin to treat infections
AR049915A1 (es)	2004-06-14	2006-09-13	Anacor Pharmaceuticals Inc	Compuestos con contenido de boro y metodos de uso de los mismos
US20060111388A1 (en)	2004-11-19	2006-05-25	University Of North Texas Health Science Center At Fort Worth	Phenanthroline and derivatives thereof used to lower intraocular pressure in an affected eye
GB0501944D0 (en)	2005-01-31	2005-03-09	Univ Cambridge Tech	Compounds for use in chemical detection and/or quantitation
KR101456815B1 (ko) *	2005-02-16	2014-10-31	아나코르 파마슈티칼스 인코포레이티드	보론함유 소분자
JP5084717B2 (ja)	2005-03-08	2012-11-28	エージェンシーフォーサイエンス，テクノロジーアンドリサーチ	キラル・ビスオキサゾリン触媒
US20060251689A1 (en)	2005-03-30	2006-11-09	Astion Development A/S	Treatment or prevention of pruritus
WO2007022437A2 (en)	2005-08-18	2007-02-22	Auspex Pharmaceuticals, Inc.	Therapeutic agents for the treatment of cancer and metabolic disorders
CN106008583A (zh)	2005-12-30	2016-10-12	安纳考尔医药公司	含硼的小分子
PL1988779T3 (pl)	2006-02-16	2015-10-30	Anacor Pharmaceuticals Inc	Małe cząsteczki zawierające bor jako środki przeciwzapalne
WO2007131072A2 (en) *	2006-05-02	2007-11-15	Anacor Pharmaceuticals, Inc.	Hydrolytically-resistant boron-containing therapeutics and methods of use
US20070286822A1 (en)	2006-06-12	2007-12-13	Anacor Pharmaceuticals Inc.	Compounds for the Treatment of Periodontal Disease
WO2007146965A2 (en)	2006-06-12	2007-12-21	Anacor Pharmaceuticals, Inc.	Compounds for the treatment of periodontal disease
KR100848491B1 (ko)	2007-01-16	2008-07-28	영진약품공업주식회사	베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar)	2007-06-20	2019-10-20	Anacor Pharmaceuticals Inc	جزيئات صغيرة تحتوي على البورون
EP2187893A4 (en)	2008-03-06	2012-02-22	Anacor Pharmaceuticals Inc	SMALL BORON-CONTAINING MOLECULES AS ANTI-INFLAMMATORY AGENTS
AU2009221793B2 (en)	2008-03-06	2015-02-19	Anacor Pharmaceuticals, Inc	Boron-containing small molecules as anti-inflammatory agents
WO2009140309A2 (en)	2008-05-12	2009-11-19	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
US8461336B2 (en)	2008-09-04	2013-06-11	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules
US9493489B2 (en)	2008-10-15	2016-11-15	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules as anti-protozoal agents
WO2010045505A1 (en)	2008-10-15	2010-04-22	Anacor Pharmaceuticals, Inc	Boron-containing small molecules as anti-protozoal agents
CA2744231A1 (en)	2008-12-17	2010-07-15	Anacor Pharmaceuticals, Inc.	Polymorphs of (s)-3-aminomethyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2] oxaborol-1-ol
AU2010281439A1 (en)	2009-07-28	2012-03-15	Anacor Pharmaceuticals, Inc.	Trisubstituted boron-containing molecules
WO2012033858A2 (en) *	2010-09-07	2012-03-15	Anacor Pharmaceuticals, Inc.	Boron-containing small molecules

2011
- 2011-09-07 WO PCT/US2011/050728 patent/WO2012033858A2/en not_active Ceased
- 2011-09-07 EA EA201390274A patent/EA028743B1/ru not_active IP Right Cessation
- 2011-09-07 KR KR1020137005717A patent/KR101949423B1/ko active Active
- 2011-09-07 EA EA201791850A patent/EA033311B1/ru unknown
- 2011-09-07 SM SM20210643T patent/SMT202100643T1/it unknown
- 2011-09-07 SG SG2013014493A patent/SG187969A1/en unknown
- 2011-09-07 JP JP2013527375A patent/JP5952280B2/ja active Active
- 2011-09-07 DK DK11758050.6T patent/DK2613788T3/da active
- 2011-09-07 PL PL17176654T patent/PL3251678T3/pl unknown
- 2011-09-07 US US13/227,444 patent/US8703742B2/en active Active
- 2011-09-07 PT PT171766546T patent/PT3251678T/pt unknown
- 2011-09-07 KR KR1020197003860A patent/KR102152901B1/ko active Active
- 2011-09-07 ES ES11758050.6T patent/ES2635333T3/es active Active
- 2011-09-07 DK DK17176654.6T patent/DK3251678T3/da active
- 2011-09-07 CA CA2810021A patent/CA2810021C/en active Active
- 2011-09-07 LT LTEP17176654.6T patent/LT3251678T/lt unknown
- 2011-09-07 RS RS20211391A patent/RS62548B1/sr unknown
- 2011-09-07 EP EP11758050.6A patent/EP2613788B1/en active Active
- 2011-09-07 CN CN201810051113.2A patent/CN108610356B/zh active Active
- 2011-09-07 ES ES17176654T patent/ES2898695T3/es active Active
- 2011-09-07 SG SG10201507032YA patent/SG10201507032YA/en unknown
- 2011-09-07 CN CN2011800427618A patent/CN103140228A/zh active Pending
- 2011-09-07 EP EP17176654.6A patent/EP3251678B1/en active Active
- 2011-09-07 BR BR112013005426-3A patent/BR112013005426B1/pt active IP Right Grant
- 2011-09-07 HU HUE17176654A patent/HUE059033T2/hu unknown
- 2011-09-07 MX MX2013002651A patent/MX338209B/es active IP Right Grant
- 2011-09-07 AU AU2011299243A patent/AU2011299243C1/en active Active
- 2011-09-07 SI SI201132017T patent/SI3251678T1/sl unknown
- 2011-09-07 HR HRP20211762TT patent/HRP20211762T1/hr unknown
2013
- 2013-02-28 IL IL225000A patent/IL225000A/en active IP Right Grant
- 2013-03-01 ZA ZA2013/01598A patent/ZA201301598B/en unknown
2014
- 2014-03-21 US US14/221,637 patent/US9751898B2/en active Active
2016
- 2016-03-13 IL IL244556A patent/IL244556B/en active IP Right Grant
- 2016-06-09 JP JP2016114971A patent/JP2016199558A/ja not_active Withdrawn
2017
- 2017-08-24 US US15/685,846 patent/US20170355719A1/en not_active Abandoned
- 2017-10-06 JP JP2017195759A patent/JP6491294B2/ja active Active
2019
- 2019-02-28 JP JP2019035145A patent/JP2019112431A/ja active Pending
- 2019-07-30 US US16/526,248 patent/US11008345B2/en active Active
2021
- 2021-11-16 CY CY20211100990T patent/CY1124728T1/el unknown

Also Published As

Publication number	Publication date
ES2898695T8 (es)	2022-03-16
HK1247841A1 (en)	2018-10-05
CA2810021A1 (en)	2012-03-15
US20170355719A1 (en)	2017-12-14
EP3251678B1 (en)	2021-10-20
JP2018058836A (ja)	2018-04-12
CN108610356A (zh)	2018-10-02
EP3251678A1 (en)	2017-12-06
ES2898695T3 (es)	2022-03-08
WO2012033858A2 (en)	2012-03-15
HUE059033T2 (hu)	2022-10-28
HRP20211762T1 (hr)	2022-02-18
IL244556A0 (en)	2016-04-21
SMT202100643T1 (it)	2022-01-10
JP6491294B2 (ja)	2019-03-27
LT3251678T (lt)	2021-12-10
US20120115813A1 (en)	2012-05-10
US20190345173A1 (en)	2019-11-14
MX338209B (es)	2016-04-07
DK2613788T3 (da)	2017-08-07
SG187969A1 (en)	2013-04-30
KR101949423B1 (ko)	2019-02-18
US20140315860A1 (en)	2014-10-23
EP2613788B1 (en)	2017-06-21
PL3251678T3 (pl)	2022-01-10
KR20190018549A (ko)	2019-02-22
MX2013002651A (es)	2013-04-19
ES2635333T3 (es)	2017-10-03
BR112013005426B1 (pt)	2021-08-24
US11008345B2 (en)	2021-05-18
CN108610356B (zh)	2021-02-26
CA2810021C (en)	2018-05-29
JP5952280B2 (ja)	2016-07-13
JP2013541514A (ja)	2013-11-14
AU2011299243B2 (en)	2015-09-17
EA028743B1 (ru)	2017-12-29
EP2613788A2 (en)	2013-07-17
PT3251678T (pt)	2021-11-22
US9751898B2 (en)	2017-09-05
EA201791850A1 (ru)	2018-01-31
IL244556B (en)	2020-07-30
IL225000A (en)	2016-03-31
SI3251678T1 (sl)	2022-01-31
KR20140093598A (ko)	2014-07-28
CY1124728T1 (el)	2022-07-22
RS62548B1 (sr)	2021-12-31
SG10201507032YA (en)	2015-10-29
JP2019112431A (ja)	2019-07-11
CN103140228A (zh)	2013-06-05
EA033311B1 (ru)	2019-09-30
JP2016199558A (ja)	2016-12-01
AU2011299243A1 (en)	2013-03-28
EA201390274A1 (ru)	2013-08-30
WO2012033858A3 (en)	2012-05-10
US8703742B2 (en)	2014-04-22
KR102152901B1 (ko)	2020-09-07
AU2011299243C1 (en)	2016-06-02
ZA201301598B (en)	2021-08-25
BR112013005426A2 (pt)	2016-06-07

Publication	Publication Date	Title
DK3251678T3 (da)	2021-11-22	Benzoxaborolderivater til behandling af bakterieinfektioner
LTC2785706I2 (lt)	2023-07-10	Pakeistieji 4-fenil-piridinai, skirti su nk-receptoriumi susijusių ligų gydymui
DK3590928T3 (da)	2021-08-30	Pyrimidinderivater til behandling af virusinfektioner
DK3520805T3 (da)	2021-04-19	Sammensætninger til behandling af myelofibrose
DK2498771T3 (da)	2014-01-27	Anvendelse af bethanechol til behandling af xerostomi
DK2852391T3 (da)	2022-02-21	Systemer til behandling af lungeinfektioner
PT2898885T (pt)	2018-02-05	Derivados de pirrolopirimidina para utilização no tratamento de infeções virais
HRP20180972T1 (hr)	2018-10-05	Kombinacija fenoksibenzamina i polimiksina e za liječenje mikrobnih infekcija
LT2558105T (lt)	2020-02-10	Bardoksolono metilas, skirtas nutukimo gydymui
BR112013014943A2 (pt)	2016-09-13	compostos úteis para o tratamento de aids
HRP20180237T1 (hr)	2018-03-09	Metode za liječenje hcv-a
ZA201405820B (en)	2016-05-25	Piperidino-pyrimidine derivatives for the treatment of viral infections
PL2523661T3 (pl)	2017-09-29	Inhibitory NKCC do leczenia autyzmu
DK3403669T3 (da)	2020-08-24	Fremgangsmåder til behandling og forebyggelse af staphylococcus aureus-infektioner og forbundne tilstande
DK2861214T3 (da)	2020-10-12	Tilpassede liposomer til behandling af bakterieinfektioner
PL2696890T3 (pl)	2021-12-27	Leczenie infekcji drobnoustrojowych
DK2773648T3 (da)	2019-05-20	Farmaceutiske forbindelser til anvendelse i behandlingen af clostridium difficile-infektion
PL2658851T3 (pl)	2015-08-31	Związki heterocykliczne odpowiednie do leczenia dyslipidemii
SMT201600059B (it)	2016-04-29	Trattamento di infezioni da streptococco
DK2501381T3 (da)	2017-11-06	Behandling af atrieflimmer
IL227747A0 (en)	2013-09-30	Combinations comprising macitentan for the treatment of glioblastoma multiforme
DK2701707T3 (da)	2020-11-02	Fremgangsmåde til behandling af dyskinesi
ITRM20120473A1 (it)	2014-04-05	Use of glycerophosphoinositols for the treatment of septic shock
DK2455064T3 (da)	2021-02-22	Indretning til behandling af periodontal sygdom
FR2994506B1 (fr)	2015-11-27	Adaptation de transistors