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LT3251678T - Benzoksaborolo dariniai, skirti bakterinių infekcijų gydymui - Google Patents

Benzoksaborolo dariniai, skirti bakterinių infekcijų gydymui

Info

Publication number
LT3251678T
LT3251678T LTEP17176654.6T LT17176654T LT3251678T LT 3251678 T LT3251678 T LT 3251678T LT 17176654 T LT17176654 T LT 17176654T LT 3251678 T LT3251678 T LT 3251678T
Authority
LT
Lithuania
Prior art keywords
benzoxyorolol
derivatives
treatment
bacterial infections
infections
Prior art date
Application number
LTEP17176654.6T
Other languages
English (en)
Inventor
Vincent Hernandez
Charles Ding
Jacob Plattner
Michael Alley
Fernando Rock
Suoming Zhang
Eric Easom
Xianfeng Li
Ding Zhou
Original Assignee
Anacor Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44653589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3251678(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Anacor Pharmaceuticals, Inc. filed Critical Anacor Pharmaceuticals, Inc.
Publication of LT3251678T publication Critical patent/LT3251678T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEP17176654.6T 2010-09-07 2011-09-07 Benzoksaborolo dariniai, skirti bakterinių infekcijų gydymui LT3251678T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38059610P 2010-09-07 2010-09-07

Publications (1)

Publication Number Publication Date
LT3251678T true LT3251678T (lt) 2021-12-10

Family

ID=44653589

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17176654.6T LT3251678T (lt) 2010-09-07 2011-09-07 Benzoksaborolo dariniai, skirti bakterinių infekcijų gydymui

Country Status (25)

Country Link
US (4) US8703742B2 (lt)
EP (2) EP2613788B1 (lt)
JP (4) JP5952280B2 (lt)
KR (2) KR101949423B1 (lt)
CN (2) CN108610356B (lt)
AU (1) AU2011299243C1 (lt)
BR (1) BR112013005426B1 (lt)
CA (1) CA2810021C (lt)
CY (1) CY1124728T1 (lt)
DK (2) DK3251678T3 (lt)
EA (2) EA033311B1 (lt)
ES (2) ES2898695T3 (lt)
HR (1) HRP20211762T1 (lt)
HU (1) HUE059033T2 (lt)
IL (2) IL225000A (lt)
LT (1) LT3251678T (lt)
MX (1) MX338209B (lt)
PL (1) PL3251678T3 (lt)
PT (1) PT3251678T (lt)
RS (1) RS62548B1 (lt)
SG (2) SG10201507032YA (lt)
SI (1) SI3251678T1 (lt)
SM (1) SMT202100643T1 (lt)
WO (1) WO2012033858A2 (lt)
ZA (1) ZA201301598B (lt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009526751A (ja) 2005-12-30 2009-07-23 アナコール ファーマシューティカルズ，インコーポレイテッド ホウ素含有小分子
WO2011019618A1 (en) 2009-08-14 2011-02-17 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
US8716478B2 (en) 2010-01-27 2014-05-06 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
CN108610356B (zh) 2010-09-07 2021-02-26 阿纳科制药公司 苯并氧杂硼杂环戊二烯衍生物用于治疗细菌感染
CA2858799A1 (en) 2011-12-22 2013-06-27 Micurx Pharmaceuticals, Inc. Tricyclic boron compounds for antimicrobial therapy
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
NZ710723A (en) 2013-01-30 2019-12-20 Agrofresh Inc Use of benzoxaboroles as volatile antimicrobial agents on meats, plants, or plant parts
US8669207B1 (en) 2013-01-30 2014-03-11 Dow Agrosciences, Llc. Compounds and compositions
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
WO2014121124A1 (en) 2013-02-01 2014-08-07 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
KR101636431B1 (ko) 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
NZ716350A (en) * 2013-08-09 2022-12-23 Glaxosmithkline Ip No 2 Ltd Tricyclic benzoxaborole compounds and uses thereof
EA038093B1 (ru) * 2013-12-20 2021-07-05 Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли
WO2016001834A1 (en) 2014-07-01 2016-01-07 Daiichi Sankyo Company, Limited Tricyclic benzoxaboroles as antibacterial agents
MA41494B1 (fr) * 2015-02-12 2020-10-28 Glaxosmithkline Ip No 2 Ltd Composés benzoxaborole substitués en position 4 et utilisations associées
TW201735792A (zh) 2016-03-07 2017-10-16 農業保鮮股份有限公司 使用苯并氧雜硼雜環戊烯化合物和防腐氣體作為作物的抗微生物劑之協同方法
US10961261B2 (en) 2017-03-01 2021-03-30 Anacor Pharmaceuticals, Inc. Oxaborole analogs and uses thereof
AU2018375795A1 (en) 2017-11-30 2020-07-02 Boragen, Inc. Benzoxaborole compounds and formulations thereof
CN108727176B (zh) * 2018-07-26 2021-05-18 荆楚理工学院 一种制备5-卤-2,3-二羟基苯甲醛的方法
WO2020041200A1 (en) 2018-08-18 2020-02-27 Boragen Inc. Solid forms of substituted benzoxaborole and compositions thereof
US20220275007A1 (en) * 2019-07-30 2022-09-01 Boragen, Inc. Flow reaction process for manufacture of boron-containing agrochemicals
CN110664756B (zh) * 2019-10-09 2020-11-17 吉林大学 一种小儿外伤喷雾剂及其制备方法
US20230340530A1 (en) 2020-08-31 2023-10-26 Pfizer Inc. Methods of Protecting RNA
WO2023246841A1 (en) * 2022-06-23 2023-12-28 Shanghai Micurx Pharmaceutical Co., Ltd. Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same
WO2023246842A1 (en) 2022-06-23 2023-12-28 Shanghai Micurx Pharmaceutical Co., Ltd. Prodrugs of boron compounds and their use in treating bacterial infections
CN115572218B (zh) * 2022-08-29 2024-04-16 江阴勒森生物科技有限公司 一种2-溴-3-羟基苯甲醛及其相关化学发光底物中间体的制备方法

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2260336A (en) 1939-10-16 1941-10-28 Dow Chemical Co Method of preparation of organic borates
US3686398A (en) 1970-07-20 1972-08-22 Chevron Res 10,9-boroxarophenanthrene as fungicides
GB1396904A (en) 1972-08-11 1975-06-11 Ici Ltd Method for the control of micro-organisms
US4766113A (en) 1975-10-24 1988-08-23 Chapman Chemical Company Antimicrobial compositions and methods of using same
US4602011A (en) 1975-10-24 1986-07-22 Chapman Chemical Company Antimicrobial compositions and methods of using same
US4716035A (en) 1985-05-24 1987-12-29 The Procter & Gamble Company Oral compositions and methods for treating gingivitis
US5962498A (en) 1986-06-11 1999-10-05 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US4894220A (en) 1987-01-30 1990-01-16 Colgate-Palmolive Company Antibacterial antiplaque oral composition
US4919934A (en) 1989-03-02 1990-04-24 Richardson-Vicks Inc. Cosmetic sticks
US5274792A (en) 1989-08-19 1993-12-28 Fujitsu Limited Information processing apparatus with parallel instruction decoding
SG47101A1 (en) 1992-07-31 1998-03-20 Us Bioscience Crystalline amifostine compositions and methods for the preparation and use of same
US5348948A (en) 1993-05-07 1994-09-20 American Cyanamid Company 2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal
US5348947A (en) 1993-05-07 1994-09-20 American Cyanamid Company Diarylboron ester and thioester fungicidal agents
US5594151A (en) 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexing reagents derived from aminosalicylic acid
GB9411587D0 (en) 1994-06-09 1994-08-03 Zeneca Ltd Compound, composition and use
US6083903A (en) 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
GB9500856D0 (en) 1995-01-17 1995-03-08 Zeneca Ltd Composition and use
US6632955B1 (en) 1996-12-02 2003-10-14 Chisso Corporation Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
GB9604926D0 (en) 1996-03-08 1996-05-08 Sandoz Ltd Organic compounds
CA2258728C (en) 1996-06-19 2011-09-27 Rhone Poulenc Rorer Limited Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
US5831046A (en) 1996-08-05 1998-11-03 Prolinx, Incorporated Boronic acid-contaning nucleic acid monomers
WO1998012206A1 (en) 1996-09-19 1998-03-26 The Board Of Trustees Of Leland Stanford Jr. University Dna adenine methyltransferases and uses thereof
US6221640B1 (en) 1997-05-14 2001-04-24 Cubist Pharmaceuticals, Inc. Enterococcal aminoacyl-trna synthetase proteins, nucleic acids and strains comprising same
DE19829947A1 (de) 1998-07-04 2000-01-05 Bayer Ag Elektrolumineszierende Anordnungen mit Bor-Chelaten
CN1335836A (zh) 1998-11-06 2002-02-13 巴斯福股份公司 三环吡唑衍生物
US6462036B1 (en) 1998-11-06 2002-10-08 Basf Aktiengesellschaft Tricyclic pyrazole derivatives
WO2000044387A1 (fr) 1999-01-29 2000-08-03 Nitto Kasei Co., Ltd. Composes organobores presentant une activite de coccidiostats
CA2373279A1 (en) 1999-05-25 2000-12-14 The Penn State Research Foundation Dna methyltransferase inhibitors
US6306628B1 (en) 1999-08-25 2001-10-23 Ambergen, Incorporated Methods for the detection, analysis and isolation of Nascent proteins
EP1767629B1 (en) 1999-08-25 2011-04-20 Ambergen, Inc. Methods for the detection, analysis and isolation of nascent proteins
WO2001025226A1 (en) 1999-10-05 2001-04-12 Bethesda Pharmaceuticals, Inc. Dithiolane derivatives
JP2003519188A (ja) 2000-01-06 2003-06-17 マランテック ホールディング リミテッド ライアビリティ カンパニー 皮膚増殖の促進及び皮膚症状の処置のための組成物及び方法
US6521619B2 (en) 2000-06-29 2003-02-18 Icos Corporation Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents
WO2002006316A2 (en) 2000-07-14 2002-01-24 Zycos, Inc. Alpha-msh related compounds and methods of use
EP1339725B1 (en) 2000-11-30 2006-11-22 The Penn State Research Foundation Dna methyl transferase inhibitors
DE10110051C2 (de) 2001-03-02 2003-07-03 Clariant Gmbh Verfahren zur Herstellung von Boron- und Borinsäuren
US6737042B2 (en) 2001-05-24 2004-05-18 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
GB0117645D0 (en) 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
DE10143979A1 (de) 2001-09-07 2003-03-27 Clariant Gmbh Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren
EP1444981A1 (en) 2001-10-11 2004-08-11 Katsuhiko Mikoshiba Intracellular calcium concentration increase inhibitors
CA2473238A1 (en) 2002-01-10 2003-07-24 The Penn State Research Foundation Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids
AU2003248921A1 (en) 2002-07-09 2004-01-23 Point Therapeutics, Inc. Boroproline compound combination therapy
DE60313357T2 (de) 2002-12-02 2008-01-03 Solvias Ag Verfahren zur katalytischen hydrierung von kohlenstoff-heteroatom-doppelbindungen
US7390806B2 (en) 2002-12-18 2008-06-24 Anacor Pharmaceuticals, Inc. Antibiotics containing borinic acid complexes and methods of use
EP1581500A4 (en) 2002-12-18 2008-03-05 Anacor Pharmaceuticals Inc ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE
WO2005000200A2 (en) 2003-05-09 2005-01-06 Sugen, Inc. Novel kinases
RU2006101228A (ru) 2003-06-16 2006-07-27 Анакор Фармасьютикалз, Инк. (Us) Гидролитически устойчивые борсодержащие терапевтические агенты и способы их применения
WO2005112970A2 (en) 2004-05-12 2005-12-01 The Brigham And Women's Hospital, Inc. Use of gelsolin to treat infections
AR049915A1 (es) 2004-06-14 2006-09-13 Anacor Pharmaceuticals Inc Compuestos con contenido de boro y metodos de uso de los mismos
WO2006062731A1 (en) 2004-11-19 2006-06-15 University Of North Texas Health Science Center At Fort Worth Phenanthroline and derivatives thereof used to lower intraocular pressure in an affected eye
GB0501944D0 (en) 2005-01-31 2005-03-09 Univ Cambridge Tech Compounds for use in chemical detection and/or quantitation
PT3424932T (pt) 2005-02-16 2021-05-19 Anacor Pharmaceuticals Inc Boronoftalidas para utilização terapêutica
EP1856113B1 (en) 2005-03-08 2016-01-06 Agency for Science, Technology and Research Chiral bisoxazoline catalysts
TW200722087A (en) 2005-03-30 2007-06-16 Astion Dev As Treatment of dermatological diseases and pruritus
US20080234229A1 (en) 2005-08-18 2008-09-25 Auspex Pharmaceuticals, Inc. Novel Therapeutic Agents for the Treatment of Cancer, Metabolic Diseases and Skin Disorders
JP2009526751A (ja) 2005-12-30 2009-07-23 アナコール ファーマシューティカルズ，インコーポレイテッド ホウ素含有小分子
RU2508113C2 (ru) 2006-02-16 2014-02-27 Анакор Фармасьютикалз, Инк. Борсодержащие малые молекулы в качестве противовоспалительных средств
JP2009536660A (ja) * 2006-05-02 2009-10-15 アナコール ファーマシューティカルズ，インコーポレイテッド 加水分解耐性ホウ素含有治療剤及びその使用方法
EP2044091A4 (en) 2006-06-12 2010-08-04 Anacor Pharmaceuticals Inc COMPOUNDS FOR THE TREATMENT OF PARODONTAL DISEASE
US20070286822A1 (en) 2006-06-12 2007-12-13 Anacor Pharmaceuticals Inc. Compounds for the Treatment of Periodontal Disease
KR100848491B1 (ko) 2007-01-16 2008-07-28 영진약품공업주식회사 베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar) * 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
WO2009111676A2 (en) 2008-03-06 2009-09-11 Anacor Pharmaceuticals, Inc Boron-containing small molecules as anti-inflammatory agents
KR20150065941A (ko) 2008-03-06 2015-06-15 아나코르 파마슈티칼스 인코포레이티드 소염제로써 붕소가 함유된 소분자
WO2009140309A2 (en) 2008-05-12 2009-11-19 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010028005A1 (en) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010045505A1 (en) 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc Boron-containing small molecules as anti-protozoal agents
US9493489B2 (en) 2008-10-15 2016-11-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
PE20120052A1 (es) 2008-12-17 2012-02-13 Anacor Pharmaceuticals Inc Polimorfos de (s)-3-amino-metil-7-(3-hidroxi-propoxi)-3h-benzo-[c][1,2]-oxaborol-1-ol
US8343944B2 (en) 2009-07-28 2013-01-01 Anacor Pharmaceuticals, Inc. Trisubstituted boron-containing molecules
CN108610356B (zh) * 2010-09-07 2021-02-26 阿纳科制药公司 苯并氧杂硼杂环戊二烯衍生物用于治疗细菌感染

Also Published As

Publication number Publication date
EP2613788B1 (en) 2017-06-21
PT3251678T (pt) 2021-11-22
US9751898B2 (en) 2017-09-05
PL3251678T3 (pl) 2022-01-10
HK1247841A1 (en) 2018-10-05
US20190345173A1 (en) 2019-11-14
JP2018058836A (ja) 2018-04-12
MX2013002651A (es) 2013-04-19
EP2613788A2 (en) 2013-07-17
KR20140093598A (ko) 2014-07-28
AU2011299243C1 (en) 2016-06-02
MX338209B (es) 2016-04-07
IL244556A0 (en) 2016-04-21
JP2016199558A (ja) 2016-12-01
AU2011299243B2 (en) 2015-09-17
JP2013541514A (ja) 2013-11-14
HRP20211762T1 (hr) 2022-02-18
EA201791850A1 (ru) 2018-01-31
SG187969A1 (en) 2013-04-30
JP5952280B2 (ja) 2016-07-13
SI3251678T1 (sl) 2022-01-31
DK2613788T3 (en) 2017-08-07
WO2012033858A3 (en) 2012-05-10
BR112013005426A2 (pt) 2016-06-07
EA201390274A1 (ru) 2013-08-30
CY1124728T1 (el) 2022-07-22
RS62548B1 (sr) 2021-12-31
BR112013005426B1 (pt) 2021-08-24
CA2810021A1 (en) 2012-03-15
CN103140228A (zh) 2013-06-05
ES2898695T3 (es) 2022-03-08
KR101949423B1 (ko) 2019-02-18
US20140315860A1 (en) 2014-10-23
ZA201301598B (en) 2021-08-25
HUE059033T2 (hu) 2022-10-28
SG10201507032YA (en) 2015-10-29
JP6491294B2 (ja) 2019-03-27
EA028743B1 (ru) 2017-12-29
EA033311B1 (ru) 2019-09-30
US20120115813A1 (en) 2012-05-10
US20170355719A1 (en) 2017-12-14
EP3251678B1 (en) 2021-10-20
ES2635333T3 (es) 2017-10-03
WO2012033858A2 (en) 2012-03-15
IL244556B (en) 2020-07-30
EP3251678A1 (en) 2017-12-06
SMT202100643T1 (it) 2022-01-10
KR102152901B1 (ko) 2020-09-07
US8703742B2 (en) 2014-04-22
JP2019112431A (ja) 2019-07-11
IL225000A (en) 2016-03-31
US11008345B2 (en) 2021-05-18
CA2810021C (en) 2018-05-29
AU2011299243A1 (en) 2013-03-28
CN108610356B (zh) 2021-02-26
DK3251678T3 (da) 2021-11-22
KR20190018549A (ko) 2019-02-22
ES2898695T8 (es) 2022-03-16
CN108610356A (zh) 2018-10-02

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