DK259080A - 4-aroylimidazol-2-oner deres fremstilling og anvendelse som antihypertensive midler cardiotonika og antithrombotika - Google Patents

4-aroylimidazol-2-oner deres fremstilling og anvendelse som antihypertensive midler cardiotonika og antithrombotika

Info

Publication number: DK259080A
Authority: DK; Denmark
Prior art keywords: anthithromotics; aroylimidazole; cardiotonics; antihypertensive; ones
Prior art date: 1979-06-18

Application number

DK259080A

Other languages

English (en)

Other versions

DK160269C (da

DK160269B (da

Inventor

R A Schettler

R C Dage

J M Grisar

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-18

Filing date

1980-06-17

Publication date

1980-12-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK259080(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-06-17 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1980-12-19 Publication of DK259080A publication Critical patent/DK259080A/da

1991-02-18 Publication of DK160269B publication Critical patent/DK160269B/da

1991-07-22 Application granted granted Critical

1991-07-22 Publication of DK160269C publication Critical patent/DK160269C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK259080A 1979-06-18 1980-06-17 Analogifremgangsmaade til fremstilling af 4-aroyl-1,3-dihydro-2h-imidazol-2-oner eller et farmaceutisk acceptabelt metalsalt eller basisk ammoniumsalt deraf DK160269C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US4980879A	1979-06-18	1979-06-18
US4980879		1979-06-18
US11920780A	1980-02-07	1980-02-07
US11920780		1980-02-07

Publications (3)

Publication Number	Publication Date
DK259080A true DK259080A (da)	1980-12-19
DK160269B DK160269B (da)	1991-02-18
DK160269C DK160269C (da)	1991-07-22

Family

ID=26727558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK259080A DK160269C (da)	1979-06-18	1980-06-17	Analogifremgangsmaade til fremstilling af 4-aroyl-1,3-dihydro-2h-imidazol-2-oner eller et farmaceutisk acceptabelt metalsalt eller basisk ammoniumsalt deraf

Country Status (20)

Country	Link
AT (1)	AT375349B (da)
AU (1)	AU532783B2 (da)
CA (1)	CA1132554A (da)
CH (1)	CH646155A5 (da)
DE (1)	DE3021792A1 (da)
DK (1)	DK160269C (da)
ES (1)	ES492255A0 (da)
FR (1)	FR2459233A1 (da)
GB (1)	GB2055364B (da)
HK (1)	HK61486A (da)
HU (1)	HU186736B (da)
IE (1)	IE50646B1 (da)
IL (1)	IL60243A (da)
IT (1)	IT1143922B (da)
MY (1)	MY8600709A (da)
NL (2)	NL193752C (da)
NO (1)	NO152841C (da)
NZ (1)	NZ193935A (da)
PH (1)	PH18683A (da)
SE (2)	SE447107B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH18106A (en) *	1981-02-18	1985-03-21	Merrell Dow Pharma	Novel-4-aroylimidazol-2-ones
US4405628A (en) *	1981-03-05	1983-09-20	Merrell Dow Pharmaceuticals Inc.	4-Pyridylimidazolones and method of use
US4329470A (en)	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329471A (en) *	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4526981A (en) *	1981-05-04	1985-07-02	Merrell Dow Pharmaceuticals Inc.	[1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4381393A (en) *	1981-05-04	1983-04-26	Merrell Dow Pharmaceuticals Inc.	4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
JPS57185266A (en) *	1981-05-04	1982-11-15	Merrell Dow Pharma	4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazole- 2-one
US4371737A (en) *	1981-05-04	1983-02-01	Merrell Dow Pharmaceuticals Inc.	5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4367236A (en)	1981-11-04	1983-01-04	Merrell Dow Pharmaceuticals Inc.	Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) *	1981-11-04	1983-10-18	Merrell Dow Pharmaceuticals Inc.	Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
CA2560528A1 (en) *	2004-03-22	2005-10-06	Myogen, Inc.	(s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
WO2005092333A1 (en) *	2004-03-22	2005-10-06	Myogen, Inc.	(r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
EP2218442A1 (en)	2005-11-09	2010-08-18	CombinatoRx, Inc.	Methods, compositions, and kits for the treatment of ophthalmic disorders
WO2008151257A2 (en)	2007-06-04	2008-12-11	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009149279A2 (en)	2008-06-04	2009-12-10	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en)	2008-07-16	2019-09-24	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
KR102034748B1 (ko)	2011-03-01	2019-10-21	시너지 파마슈티컬즈 인코포레이티드	구아닐레이트 사이클라제 c 작용제의 제조 방법
EP2804603A1 (en)	2012-01-10	2014-11-26	President and Fellows of Harvard College	Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en)	2013-02-25	2017-01-17	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
EP2970384A1 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
WO2014151200A2 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
AU2014274812B2 (en)	2013-06-05	2018-09-27	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2015021358A2 (en)	2013-08-09	2015-02-12	Dominique Charmot	Compounds and methods for inhibiting phosphate transport
CN114340631A (zh)	2019-05-21	2022-04-12	阿德利克斯股份有限公司	用于降低患者的血清磷酸盐的组合
CN114539157B (zh) *	2022-03-03	2023-12-22	曲靖师范学院	一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2441933A (en) *	1945-07-30	1948-05-18	Hoffmann La Roche	Substituted imidazolones and process of making them

1980
- 1980-06-04 NZ NZ193935A patent/NZ193935A/en unknown
- 1980-06-05 IE IE1162/80A patent/IE50646B1/en not_active IP Right Cessation
- 1980-06-06 SE SE8004253A patent/SE447107B/sv not_active IP Right Cessation
- 1980-06-06 IL IL60243A patent/IL60243A/xx unknown
- 1980-06-06 AU AU59118/80A patent/AU532783B2/en not_active Expired
- 1980-06-09 ES ES492255A patent/ES492255A0/es active Granted
- 1980-06-11 DE DE19803021792 patent/DE3021792A1/de active Granted
- 1980-06-13 AT AT0314280A patent/AT375349B/de not_active IP Right Cessation
- 1980-06-16 CH CH462780A patent/CH646155A5/de not_active IP Right Cessation
- 1980-06-16 PH PH24143A patent/PH18683A/en unknown
- 1980-06-17 DK DK259080A patent/DK160269C/da not_active IP Right Cessation
- 1980-06-17 NL NL8003498A patent/NL193752C/nl not_active IP Right Cessation
- 1980-06-17 CA CA354,197A patent/CA1132554A/en not_active Expired
- 1980-06-17 HU HU801506A patent/HU186736B/hu unknown
- 1980-06-17 NO NO801796A patent/NO152841C/no unknown
- 1980-06-17 FR FR8013434A patent/FR2459233A1/fr active Granted
- 1980-06-17 IT IT48997/80A patent/IT1143922B/it active Protection Beyond IP Right Term
- 1980-06-18 GB GB8019898A patent/GB2055364B/en not_active Expired
1985
- 1985-03-25 SE SE8501452A patent/SE464559B/sv not_active IP Right Cessation
1986
- 1986-08-21 HK HK614/86A patent/HK61486A/xx not_active IP Right Cessation
- 1986-12-30 MY MY709/86A patent/MY8600709A/xx unknown
2000
- 2000-09-04 NL NL300015C patent/NL300015I1/nl unknown

Also Published As

Publication number	Publication date
SE8004253L (sv)	1980-12-19
GB2055364B (en)	1983-06-08
NL300015I1 (nl)	2000-11-01
CH646155A5 (de)	1984-11-15
IL60243A (en)	1987-01-30
NZ193935A (en)	1985-05-31
ES8105299A1 (es)	1981-06-01
SE8501452L (sv)	1985-03-25
NO152841C (no)	1985-11-27
DK160269C (da)	1991-07-22
GB2055364A (en)	1981-03-04
AU532783B2 (en)	1983-10-13
IE801162L (en)	1980-12-18
NO152841B (no)	1985-08-19
ATA314280A (de)	1983-12-15
NL193752C (nl)	2000-09-04
DK160269B (da)	1991-02-18
NO801796L (no)	1980-12-19
NL8003498A (nl)	1980-12-22
FR2459233A1 (fr)	1981-01-09
MY8600709A (en)	1986-12-31
NL300015I2 (nl)	2000-10-02
HK61486A (en)	1986-08-29
IT8048997A0 (it)	1980-06-17
DE3021792C2 (da)	1989-08-10
SE8501452D0 (sv)	1985-03-25
IT1143922B (it)	1986-10-29
IL60243A0 (en)	1980-09-16
SE464559B (sv)	1991-05-13
PH18683A (en)	1985-08-29
HU186736B (en)	1985-09-30
NL193752B (nl)	2000-05-01
AU5911880A (en)	1981-01-08
DE3021792A1 (de)	1981-01-22
SE447107B (sv)	1986-10-27
ES492255A0 (es)	1981-06-01
AT375349B (de)	1984-07-25
IE50646B1 (en)	1986-06-11
FR2459233B1 (da)	1983-09-23
CA1132554A (en)	1982-09-28

Similar Documents

Publication	Publication Date	Title
DK259080A (da)	1980-12-19	4-aroylimidazol-2-oner deres fremstilling og anvendelse som antihypertensive midler cardiotonika og antithrombotika
DK155583D0 (da)	1983-04-07	Hydantoiner, deres fremstilling og anvendelse
DK168579A (da)	1979-10-26	Corticoid-21-halogen-17-alkylcarbonater deres fremstilling og anvendelse
DK301980A (da)	1981-01-13	Nikkomyciner i,j, og n, deres fremstilling og anvendelse
DK275487A (da)	1987-12-01	1,2,3,6-tetrahydro-5-nitro-pyrimidinderivater, fremgangsmaade til deres fremstilling og deres anvendelse til bekaempelse af skadelige organismer
DK156579A (da)	1979-10-19	Oximino-triazolyl-ethaner deres fremstilling og anvendelse som fungicider
DK547378A (da)	1979-06-03	1-n-4,6-di-o(aminoglycosyl-)-1,3-dimino-cyclitol-derivater deres fremstilling og anvendelse
DK488180A (da)	1981-05-18	Tetrazolyloxycarboxylsyreamider fremgangsmaade til deres fremstilling og deres anvendelse som herbicider
DK401180A (da)	1981-03-25	Acylerede triazolyl-gamma-fluorpinacolylderivater fremgangsmaader til deres fremstilling og deres anvendelse som fungicider
DK278178A (da)	1978-12-22	Sulfamoylarylketoner deres fremstilling og anvendelse
DK328580A (da)	1981-02-01	Glycolipider og deres anvendelse som immunologiske adjuvanser
DK205180A (da)	1980-11-11	Fluorerede 1-triazolyl-butan-derivater deres fremstilling og anvendelse som fungicider
DK172183D0 (da)	1983-04-19	Ozazolderivater, deres fremstilling og anvendelse
DK364782A (da)	1983-02-15	Cyclophosphamid-derivater, deres fremstilling og anvendelse
DK375077A (da)	1978-02-26	Substituerede benzoylureidodiphenylethere fremgangsmaade til deres fremstilling og deres anvendelse som insecticider
DK284678A (da)	1978-12-25	2-arylamino-3,5-dinitro-benzotrifluorider deres fremstilling og deres anvendelse til bekaempelse af skadelige arganismer
DK326980A (da)	1981-01-31	25-halogen-cholest-5-en-3beta,22-dioler og estere deraf deres fremstilling og anvendelse
DK319478A (da)	1979-01-19	Angiotensinpeptider og deres fremstilling
DK24280A (da)	1980-07-23	Spiro-quinolylhydantoiner fremgangsmaade til deres fremstilling og deres anvendelse
DK172177A (da)	1977-10-21	Triazapentadiener fremgangsmade til deres fremstilling og acaricide kompositioner
DK401280A (da)	1981-03-25	Acylerede imidazolyl-gamma-fluorpinacolyl-derivater fremgangsmaade til deres fremstilling og deres anvendelse som fungicider
DK158680A (da)	1980-11-26	Halogenalkyl-polyhalogenquinoxalin-sulfonater deres fremstilling og anvendelse som fungicider
DK477778A (da)	1979-04-27	17alfa-(3-jodbenzoyloxy)-9alfa-4-pregnen-3,20-dioner deres d-homoanaloge og fremgangsmaade til deres fremstilling og deres anvendelse
DK513784A (da)	1985-04-30	Iodacetamider, deres fremstilling og anvendelse til skadedyrsbekaempelse
DK156783A (da)	1983-10-11	N-pteridinylurinstoffer, deres fremstilling og anvendelse

Legal Events

Date	Code	Title	Description
2000-07-10	PUP	Patent expired