DK326980A - 25-halogen-cholest-5-en-3beta,22-dioler og estere deraf deres fremstilling og anvendelse - Google Patents

25-halogen-cholest-5-en-3beta,22-dioler og estere deraf deres fremstilling og anvendelse

Info

Publication number: DK326980A
Authority: DK; Denmark
Prior art keywords: dioles; cholest; 3beta; esters; halogen
Prior art date: 1979-07-30

Application number

DK326980A

Other languages

English (en)

Other versions

DK146390C (da

DK146390B (da

Inventor

R J Chorvat

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-07-30

Filing date

1980-07-29

Publication date

1981-01-31

1980-07-29 Application filed by Searle & Co filed Critical Searle & Co

1981-01-31 Publication of DK326980A publication Critical patent/DK326980A/da

1983-09-26 Publication of DK146390B publication Critical patent/DK146390B/da

1984-03-05 Application granted granted Critical

1984-03-05 Publication of DK146390C publication Critical patent/DK146390C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK326980A 1979-07-30 1980-07-29 Analogifremgangsmaade til fremstilling af 25-halogen-cholest-5-en-3beta,22-dioler eller estere deraf DK146390C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/061,731 US4230626A (en)	1979-07-30	1979-07-30	25-Halocholest-5-ene-3β,22-diols and esters thereof
US6173179		1979-07-30

Publications (3)

Publication Number	Publication Date
DK326980A true DK326980A (da)	1981-01-31
DK146390B DK146390B (da)	1983-09-26
DK146390C DK146390C (da)	1984-03-05

Family

ID=22037752

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK326980A DK146390C (da)	1979-07-30	1980-07-29	Analogifremgangsmaade til fremstilling af 25-halogen-cholest-5-en-3beta,22-dioler eller estere deraf

Country Status (23)

Country	Link
US (1)	US4230626A (da)
JP (1)	JPS5622799A (da)
AT (1)	ATA395380A (da)
AU (1)	AU532108B2 (da)
BE (1)	BE884532A (da)
CA (1)	CA1144539A (da)
CH (1)	CH645651A5 (da)
DE (1)	DE3028643A1 (da)
DK (1)	DK146390C (da)
ES (1)	ES493810A0 (da)
FI (1)	FI802368A7 (da)
FR (1)	FR2462444A1 (da)
GB (1)	GB2056992B (da)
GR (1)	GR69347B (da)
IE (1)	IE50037B1 (da)
IL (1)	IL60700A0 (da)
IT (1)	IT1128554B (da)
NL (1)	NL8004366A (da)
NO (1)	NO802277L (da)
NZ (1)	NZ194490A (da)
PT (1)	PT71621A (da)
SE (1)	SE430508B (da)
ZA (1)	ZA804617B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4348328A (en) *	1981-11-09	1982-09-07	G.D. Searle & Co.	25-Substituted-5α-cholestane-3β,22S-diol
US5041432A (en) *	1987-01-30	1991-08-20	E. I. Du Pont De Nemours And Company	Steroid derivatives useful as hypocholesterolemics
US5034548A (en) *	1987-01-30	1991-07-23	E. I. Du Pont De Nemours And Company	Steroid derivatives useful as hypocholesterolemics
US5219879A (en) *	1990-03-05	1993-06-15	Du Pont Merck Pharmaceutical Company	Heterocyclic steroid compounds
HUP9904616A3 (en)	1996-12-20	2001-02-28	Novo Nordisk As	Meiosis regulating cholestane-derivatives
US6083497A (en) *	1997-11-05	2000-07-04	Geltex Pharmaceuticals, Inc.	Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
KR20010043558A (ko) *	1998-05-13	2001-05-25	한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느	감수분열 조절 화합물
CN113956133B (zh) *	2021-11-08	2025-01-28	湖南科瑞生物制药股份有限公司	25-羟基甾体化合物的合成方法、其侧链的制备方法以及侧链中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4069321A (en) *	1975-10-14	1978-01-17	Merck & Co., Inc.	Blocked cholecalciferol and dihydrotachysterol 3 derivatives
ES472877A1 (es) *	1977-08-29	1979-02-16	Searle & Co	Procedimiento para preparar derivados de 25-alquilcolesterol

1979
- 1979-07-30 US US06/061,731 patent/US4230626A/en not_active Expired - Lifetime
1980
- 1980-07-29 FI FI802368A patent/FI802368A7/fi not_active Application Discontinuation
- 1980-07-29 CA CA000357259A patent/CA1144539A/en not_active Expired
- 1980-07-29 GR GR62565A patent/GR69347B/el unknown
- 1980-07-29 PT PT71621A patent/PT71621A/pt unknown
- 1980-07-29 NO NO802277A patent/NO802277L/no unknown
- 1980-07-29 BE BE0/201573A patent/BE884532A/fr not_active IP Right Cessation
- 1980-07-29 FR FR8016688A patent/FR2462444A1/fr active Granted
- 1980-07-29 SE SE8005430A patent/SE430508B/sv not_active IP Right Cessation
- 1980-07-29 DK DK326980A patent/DK146390C/da active
- 1980-07-29 IL IL60700A patent/IL60700A0/xx unknown
- 1980-07-29 ES ES493810A patent/ES493810A0/es active Granted
- 1980-07-29 NZ NZ194490A patent/NZ194490A/xx unknown
- 1980-07-29 GB GB8024722A patent/GB2056992B/en not_active Expired
- 1980-07-29 DE DE19803028643 patent/DE3028643A1/de active Granted
- 1980-07-29 AU AU60883/80A patent/AU532108B2/en not_active Ceased
- 1980-07-30 JP JP10495080A patent/JPS5622799A/ja active Granted
- 1980-07-30 IT IT49382/80A patent/IT1128554B/it active
- 1980-07-30 CH CH580380A patent/CH645651A5/de not_active IP Right Cessation
- 1980-07-30 NL NL8004366A patent/NL8004366A/xx not_active Application Discontinuation
- 1980-07-30 AT AT0395380A patent/ATA395380A/de not_active IP Right Cessation
- 1980-07-30 IE IE1590/80A patent/IE50037B1/en unknown
- 1980-07-30 ZA ZA00804617A patent/ZA804617B/xx unknown

Also Published As

Publication number	Publication date
AU532108B2 (en)	1983-09-15
DK146390C (da)	1984-03-05
IE801590L (en)	1981-01-30
NZ194490A (en)	1983-03-15
ES8106540A1 (es)	1981-06-16
DE3028643C2 (da)	1990-04-12
ES493810A0 (es)	1981-06-16
AU6088380A (en)	1981-02-05
CH645651A5 (de)	1984-10-15
NL8004366A (nl)	1981-02-03
PT71621A (en)	1980-08-01
GB2056992B (en)	1983-06-22
IT8049382A0 (it)	1980-07-30
GB2056992A (en)	1981-03-25
SE430508B (sv)	1983-11-21
IE50037B1 (en)	1986-02-05
IL60700A0 (en)	1980-09-16
FI802368A7 (fi)	1981-01-01
NO802277L (no)	1981-02-02
GR69347B (da)	1982-05-18
DE3028643A1 (de)	1981-02-19
FR2462444B1 (da)	1983-05-20
IT1128554B (it)	1986-05-28
ATA395380A (de)	1983-11-15
SE8005430L (sv)	1981-01-31
BE884532A (fr)	1981-01-29
US4230626A (en)	1980-10-28
CA1144539A (en)	1983-04-12
DK146390B (da)	1983-09-26
FR2462444A1 (fr)	1981-02-13
ZA804617B (en)	1982-03-31
JPS5622799A (en)	1981-03-03
JPS6360037B2 (da)	1988-11-22

Publication	Publication Date	Title
DK540280A (da)	1981-06-20	Sulfonylurinstoffer deres fremstilling og anvendelse
DK168579A (da)	1979-10-26	Corticoid-21-halogen-17-alkylcarbonater deres fremstilling og anvendelse
DK445978A (da)	1979-04-08	Chromanderivater deres fremstilling og anvendelsesom insecticider og acaricider
DK349978A (da)	1979-06-16	Lagerstabile mikroorganismepraeparater samt deres fremstilling og anvendelse
DK242578A (da)	1978-12-02	Tetrahydrofuranderivater deres fremstilling og anvendelse
DK299676A (da)	1977-01-05	Polyestere og fremgangsmader til deres fremstilling og anvendelse
DK395580A (da)	1981-04-02	Aminosyrederivater deres fremstilling og anvendelse
DK301980A (da)	1981-01-13	Nikkomyciner i,j, og n, deres fremstilling og anvendelse
DK543879A (da)	1980-06-21	Monoazopigmentblandinger deres fremstilling og anvendelse
DK290780A (da)	1981-01-07	Dekorative tekstilelementer deres fremstilling og anvendelse
DK278178A (da)	1978-12-22	Sulfamoylarylketoner deres fremstilling og anvendelse
DK291478A (da)	1978-12-29	N!-phenyl-n-methylurinstofderivater deres fremstilling og anvendelse
DK205180A (da)	1980-11-11	Fluorerede 1-triazolyl-butan-derivater deres fremstilling og anvendelse som fungicider
DK168879A (da)	1979-10-27	Beta-lactamantibiotika og deres fremstilling
DK155380A (da)	1980-10-12	Distyrylbiphenyler deres fremstilling og anvendelse
DK326980A (da)	1981-01-31	25-halogen-cholest-5-en-3beta,22-dioler og estere deraf deres fremstilling og anvendelse
DK155280A (da)	1980-10-12	Distyrylbenzener deres fremstilling og anvendelse
DK286480A (da)	1981-01-04	Oxinethere deres fremstilling og anvendelse
DK301680A (da)	1981-01-14	N-carboxylerede carbamater deres fremstilling og anvendelse
DK50677A (da)	1977-08-10	Thiadiazolylylbenzamider og fremgangsmade til deres fremstilling
DK286580A (da)	1981-01-04	Thiazolinderivater deres fremstilling og anvendelse
DK319478A (da)	1979-01-19	Angiotensinpeptider og deres fremstilling
DK169481A (da)	1981-10-19	Kobberphthalocyaninpigmenter deres fremstilling og deres anvendelse
DK254077A (da)	1977-12-10	Benzylcyanocetaler deres fremstilling og anvendelse
DK24280A (da)	1980-07-23	Spiro-quinolylhydantoiner fremgangsmaade til deres fremstilling og deres anvendelse