DK201784A - Phenethanolaminderivater - Google Patents

Phenethanolaminderivater Download PDF

Info

Publication number: DK201784A
Authority: DK; Denmark
Prior art keywords: phenethanolamine
Prior art date: 1983-04-18

Application number

DK201784A

Other languages

English (en)

Other versions

DK201784D0 (da

DK167493B1 (da

Inventor

Ian Frederick Skidmore

Lawrence Henry Charles Lunts

Harry Finch

Alan Naylor

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-04-18

Filing date

1984-04-18

Publication date

1984-10-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27449465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK201784(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1983-04-18 Priority claimed from GB838310477A external-priority patent/GB8310477D0/en

1983-06-23 Priority claimed from GB838317087A external-priority patent/GB8317087D0/en

1983-11-04 Priority claimed from GB838329568A external-priority patent/GB8329568D0/en

1984-01-25 Priority claimed from GB848401889A external-priority patent/GB8401889D0/en

1984-04-18 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1984-04-18 Publication of DK201784D0 publication Critical patent/DK201784D0/da

1984-10-19 Publication of DK201784A publication Critical patent/DK201784A/da

1992-12-30 Priority to DK199201580A priority Critical patent/DK175083B1/da

1993-11-08 Application granted granted Critical

1993-11-08 Publication of DK167493B1 publication Critical patent/DK167493B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
- C07C43/1742—Unsaturated ethers containing halogen containing six-membered aromatic rings with halogen atoms bound to the aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Epoxy Compounds (AREA)
Pyrane Compounds (AREA)

DK201784A 1983-04-18 1984-04-18 Phenethanolaminderivater og fysiologisk acceptable syreadditionssalte og solvater deraf og et farmaceutisk praeparat deraf DK167493B1 (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK199201580A DK175083B1 (da)	1983-04-18	1992-12-30	Aminderivater, som kan anvendes til fremstilling af phenethanolaminforbindelser

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
GB838310477A GB8310477D0 (en)	1983-04-18	1983-04-18	Chemical compounds
GB8310477		1983-04-18
GB8317087		1983-06-23
GB838317087A GB8317087D0 (en)	1983-06-23	1983-06-23	Chemical compounds
GB838329568A GB8329568D0 (en)	1983-11-04	1983-11-04	Chemical compounds
GB8329568		1983-11-04
GB8401889		1984-01-25
GB848401889A GB8401889D0 (en)	1984-01-25	1984-01-25	Chemical compounds

Publications (3)

Publication Number	Publication Date
DK201784D0 DK201784D0 (da)	1984-04-18
DK201784A true DK201784A (da)	1984-10-19
DK167493B1 DK167493B1 (da)	1993-11-08

Family

ID=27449465

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK201784A DK167493B1 (da)	1983-04-18	1984-04-18	Phenethanolaminderivater og fysiologisk acceptable syreadditionssalte og solvater deraf og et farmaceutisk praeparat deraf
DK199201580A DK175083B1 (da)	1983-04-18	1992-12-30	Aminderivater, som kan anvendes til fremstilling af phenethanolaminforbindelser

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK199201580A DK175083B1 (da)	1983-04-18	1992-12-30	Aminderivater, som kan anvendes til fremstilling af phenethanolaminforbindelser

Country Status (37)

Country	Link
US (5)	US4992474A (da)
JP (2)	JPS63264443A (da)
KR (1)	KR920004186B1 (da)
AR (3)	AR244199A1 (da)
AT (1)	AT390611B (da)
AU (1)	AU573212B2 (da)
BE (1)	BE899448A (da)
BG (1)	BG61490B2 (da)
CA (2)	CA1335999C (da)
CH (2)	CH661497A5 (da)
CY (1)	CY1482A (da)
CZ (1)	CZ285602B6 (da)
DE (4)	DE3448452C2 (da)
DK (2)	DK167493B1 (da)
ES (2)	ES531722A0 (da)
FI (1)	FI85011C (da)
FR (1)	FR2545482B1 (da)
GB (2)	GB2140800B (da)
GR (1)	GR79925B (da)
HK (1)	HK36889A (da)
HU (1)	HU200160B (da)
IE (1)	IE57237B1 (da)
IL (1)	IL71569A (da)
IT (1)	IT1199112B (da)
KE (1)	KE3864A (da)
LU (2)	LU88265I2 (da)
MX (1)	MX9203226A (da)
MY (1)	MY102087A (da)
NL (2)	NL188406C (da)
NO (2)	NO159016C (da)
NZ (2)	NZ207885A (da)
PH (1)	PH21574A (da)
PT (1)	PT78443B (da)
SE (1)	SE462594B (da)
SG (1)	SG12289G (da)
SK (1)	SK278120B6 (da)
ZW (1)	ZW6584A1 (da)

Families Citing this family (181)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZW6584A1 (en) *	1983-04-18	1985-04-17	Glaxo Group Ltd	Phenethanolamine derivatives
DE3513885A1 (de) *	1984-04-17	1985-10-17	Glaxo Group Ltd., London	Phenethanolaminverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4943591A (en) *	1984-10-17	1990-07-24	Glaxo Group Limited	Dichloroaniline derivatives
GB8525321D0 (en) *	1985-10-15	1985-11-20	Glaxo Group Ltd	Chemical compounds
GB8525483D0 (en) *	1985-10-16	1985-11-20	Glaxo Group Ltd	Chemical compounds
GB8525484D0 (en) *	1985-10-16	1985-11-20	Glaxo Group Ltd	Chemical compounds
EP0223410A3 (en) *	1985-10-16	1987-11-19	Glaxo Group Limited	Ethanolamine derivatives
EP0220054A3 (en) *	1985-10-16	1987-12-02	Glaxo Group Limited	Ethanolamine derivatives
JPS63290852A (ja) *	1987-02-10	1988-11-28	グラクソ、グループ、リミテッド	化合物
JPS6485964A (en) *	1987-03-12	1989-03-30	Glaxo Group Ltd	Compound
GB8718938D0 (en) *	1987-08-11	1987-09-16	Glaxo Group Ltd	Chemical compounds
GB8718940D0 (en) *	1987-08-11	1987-09-16	Glaxo Group Ltd	Chemical compounds
JPH0228141A (ja) *	1987-11-13	1990-01-30	Glaxo Group Ltd	フェネタノールアミン誘導体
NZ227365A (en) *	1987-12-18	1990-10-26	Glaxo Group Ltd	Aromatic amino ethers and pharmaceutical compositions
ZA889405B (en) *	1987-12-18	1989-12-27	Glaxo Group Ltd	Ethanolamine derivatives
GB8909273D0 (en) *	1989-04-24	1989-06-07	Glaxo Group Ltd	Chemical compounds
GB2230775A (en) *	1989-04-24	1990-10-31	Glaxo Group Ltd	Phenethanolamine compounds
US5290815A (en) *	1989-09-07	1994-03-01	Glaxo Group Limited	Treatment of inflammation and allergy
EP1078629A3 (en) *	1989-09-07	2001-05-23	Glaxo Group Limited	Use of Salmeterol and salts for the treatment of inflammation and allergy
US5270305A (en) *	1989-09-08	1993-12-14	Glaxo Group Limited	Medicaments
NZ235222A (en) *	1989-09-08	1992-11-25	Glaxo Group Ltd	Inhalatory composition comprising salmeterol and beclomethasone dipropionate
US5208226A (en) *	1989-09-08	1993-05-04	Glaxo Group Limited	Medicaments
IL95590A (en) *	1989-09-08	1996-06-18	Glaxo Group Ltd	Medicinal preparations containing Salmetrol and Pluticasone Propionate
TW209832B (da) *	1989-10-10	1993-07-21	Glaxo Group Ltd
US6536427B2 (en)	1990-03-02	2003-03-25	Glaxo Group Limited	Inhalation device
TW197380B (da)	1990-03-02	1993-01-01	Glaxo Group Ltd
SK280967B6 (sk)	1990-03-02	2000-10-09	Glaxo Group Limited	Inhalačný prístroj
US5919827A (en) *	1990-07-11	1999-07-06	Sepracor Inc.	Method for treating asthma using optically pure R(-) salmeterol
GB9026005D0 (en) *	1990-11-29	1991-01-16	Glaxo Group Ltd	Drug material suitable for micronisation
AU1229892A (en) *	1992-02-11	1993-09-03	Glaxo Group Limited	Benzenedimethanol derivative suitable for micronisation
CN1056974C (zh) *	1992-02-11	2000-10-04	格拉克索公司	适宜于微粒化的药物材料的制备方法
AP323A (en) *	1992-05-08	1994-03-07	Glaxo Group Ltd	Drug material suitable for micronisation.
GB9215274D0 (en) *	1992-07-17	1992-09-02	Scras	Derivatives of(phenylethyl-beta-ol)amine
ES2065269B1 (es) *	1993-05-11	1995-10-01	S A L V A T Lab Sa	6-(4-(fenilbutoxi) hexilaminometil-4-hidroxi-a1,a3-bencenodimetanol. procedimiento para la obtencion del mismo y nuevos intermedios utilizados en su preparacion.
CA2177171C (en) *	1993-12-10	2006-01-17	Alfred Sallmann	Novel substituted oxazolidines
GB9507768D0 (en) *	1995-04-13	1995-05-31	Glaxo Group Ltd	Method of apparatus
EP0820414B1 (en)	1995-04-14	2004-02-04	SmithKline Beecham Corporation	Metered dose inhaler for beclomethasone dipropionate
EP0820279B1 (en)	1995-04-14	2002-07-03	Smithkline Beecham Corporation	Metered dose inhaler for albuterol
NZ305787A (en)	1995-04-14	1999-07-29	Glaxo Wellcome Inc	Metered dose inhaler for fluticasone propionate
RO119116B1 (ro)	1995-04-14	2004-04-30	Glaxo Wellcome Inc.	Inhalator pentru dozarea salmeterolului
US6632955B1 (en)	1996-12-02	2003-10-14	Chisso Corporation	Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
US6254882B1 (en)	1997-09-16	2001-07-03	Sepracor Inc.	Methods and compositions for treating pulmonary disorders using optically pure (S)—salmeterol
CA2333903A1 (en) *	1998-06-01	1999-12-09	Anthony J. Verbiscar	Topical transdermal treatments
ES2142771B1 (es) *	1998-09-28	2001-01-01	Vita Invest Sa	Nuevos derivados de la 6-(4-fenil-butoxi) hexilamina y procedimiento para la obtencion de salmeterol.
PT1169019E (pt)	1999-04-14	2003-07-31	Glaxo Group Ltd	Formulacao farmaceutica em aerossol
AU777012B2 (en) *	1999-08-21	2004-09-30	Takeda Gmbh	Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist
GB0009613D0 (en) *	2000-04-18	2000-06-07	Glaxo Group Ltd	Pharmaceutical compositions
GB0009609D0 (en) *	2000-04-18	2000-06-07	Glaxo Group Ltd	Therapeutic compositions
GB0014546D0 (en) *	2000-06-14	2000-08-09	Glaxo Group Ltd	A novel process
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- 1984-04-18 KR KR1019840002030A patent/KR920004186B1/ko not_active Expired
- 1984-04-18 DE DE1995175029 patent/DE19575029I2/de active Active
- 1984-04-18 NO NO841568A patent/NO159016C/no not_active IP Right Cessation
- 1984-04-18 CA CA000452288A patent/CA1335999C/en not_active Expired - Lifetime
- 1984-04-18 DE DE3448338A patent/DE3448338C2/de not_active Expired - Lifetime
- 1984-04-18 SE SE8402188A patent/SE462594B/sv not_active IP Right Cessation
- 1984-04-18 NZ NZ221999A patent/NZ221999A/xx unknown
- 1984-04-18 LU LU88265C patent/LU88265I2/xx unknown
- 1984-04-18 GR GR74450A patent/GR79925B/el unknown
- 1984-04-18 HU HU841498A patent/HU200160B/hu unknown
- 1984-04-18 FR FR8406115A patent/FR2545482B1/fr not_active Expired
- 1984-04-18 NL NLAANVRAGE8401258,A patent/NL188406C/xx not_active IP Right Cessation
- 1984-04-18 PT PT78443A patent/PT78443B/pt unknown
- 1984-04-18 DK DK201784A patent/DK167493B1/da not_active IP Right Cessation
- 1984-04-18 AU AU27064/84A patent/AU573212B2/en not_active Expired
- 1984-04-18 PH PH30586A patent/PH21574A/en unknown
- 1984-04-18 GB GB08410124A patent/GB2140800B/en not_active Expired
- 1984-04-18 ES ES531722A patent/ES531722A0/es active Granted
- 1984-04-18 DE DE19843414752 patent/DE3414752A1/de active Granted
- 1984-04-18 LU LU85329A patent/LU85329A1/fr active Protection Beyond IP Right Term
- 1984-04-18 IE IE965/84A patent/IE57237B1/en not_active IP Right Cessation
- 1984-04-18 AT AT0129184A patent/AT390611B/de not_active IP Right Cessation
- 1984-04-18 CH CH4750/86A patent/CH667084A5/fr not_active IP Right Cessation
1985
- 1985-01-16 ES ES539625A patent/ES8609209A1/es not_active Expired
1986
- 1986-05-21 GB GB08612357A patent/GB2176476B/en not_active Expired
1987
- 1987-02-25 AR AR87306841A patent/AR245687A1/es active
- 1987-09-29 MY MYPI87002277A patent/MY102087A/en unknown
1988
- 1988-02-25 JP JP63043277A patent/JPS63264443A/ja active Granted
1989
- 1989-02-08 AR AR89313169A patent/AR247721A1/es active
- 1989-02-17 KE KE3864A patent/KE3864A/xx unknown
- 1989-02-24 SG SG122/89A patent/SG12289G/en unknown
- 1989-05-04 HK HK368/89A patent/HK36889A/xx not_active IP Right Cessation
- 1989-08-23 US US07/397,664 patent/US4992474A/en not_active Expired - Lifetime
- 1989-12-08 CY CY1482A patent/CY1482A/en unknown
1990
- 1990-06-21 US US07/541,631 patent/US5091422A/en not_active Expired - Lifetime
- 1990-11-29 US US07/619,899 patent/US5126375A/en not_active Expired - Lifetime
1991
- 1991-12-19 US US07/810,183 patent/US5243076A/en not_active Expired - Lifetime
- 1991-12-23 CZ CS914028A patent/CZ285602B6/cs unknown
- 1991-12-23 SK SK4028-91A patent/SK278120B6/sk unknown
1992
- 1992-02-19 US US07/837,783 patent/US5225445A/en not_active Expired - Lifetime
- 1992-06-24 MX MX9203226A patent/MX9203226A/es unknown
- 1992-08-18 CA CA000616467A patent/CA1336004C/en not_active Expired - Lifetime
- 1992-08-18 JP JP4219484A patent/JPH0729997B2/ja not_active Expired - Lifetime
- 1992-12-30 DK DK199201580A patent/DK175083B1/da not_active IP Right Cessation
1993
- 1993-06-11 NL NL930066C patent/NL930066I2/nl unknown
- 1993-08-20 BG BG098059A patent/BG61490B2/bg unknown
1994
- 1994-09-22 NO NO1994017C patent/NO1994017I1/no unknown

Also Published As

Publication number	Publication date
CH667084A5 (fr)	1988-09-15
NL930066I1 (nl)	1993-09-01
JPS63264443A (ja)	1988-11-01
HK36889A (en)	1989-05-12
FI841548A7 (fi)	1984-10-19
DK175083B1 (da)	2004-05-24
BG61490B2 (bg)	1997-09-30
KR840009063A (ko)	1984-12-24
IT8448064A0 (it)	1984-04-18
AU573212B2 (en)	1988-06-02
ES539625A0 (es)	1986-07-16
NO159016C (no)	1988-11-23
ES8505641A1 (es)	1985-06-01
KR920004186B1 (ko)	1992-05-30
CZ285602B6 (cs)	1999-09-15
JPH0729997B2 (ja)	1995-04-05
AR247721A1 (es)	1995-03-31
DE3414752A1 (de)	1984-10-18
DK201784D0 (da)	1984-04-18
US5225445A (en)	1993-07-06
AR244199A1 (es)	1993-10-29
KE3864A (en)	1989-05-19
FR2545482A1 (fr)	1984-11-09
SK402891A3 (en)	1995-07-11
MX9203226A (es)	1992-07-01
US5243076A (en)	1993-09-07
AR245687A1 (es)	1994-02-28
PT78443A (pt)	1984-05-01
FI85011B (fi)	1991-11-15
IL71569A0 (en)	1984-07-31
FI841548A0 (fi)	1984-04-18
DK158092A (da)	1992-12-30
IT8448064A1 (it)	1985-10-18
NL8401258A (nl)	1984-11-16
NO841568L (no)	1984-10-19
LU85329A1 (fr)	1985-06-04
GB8410124D0 (en)	1984-05-31
NL188406B (nl)	1992-01-16
NO1994017I1 (no)	1994-09-22
NZ207885A (en)	1988-11-29
BE899448A (fr)	1984-10-18
CZ402891A3 (en)	1993-05-12
GB2140800A (en)	1984-12-05
ES8609209A1 (es)	1986-07-16
US5126375A (en)	1992-06-30
SE462594B (sv)	1990-07-23
MY102087A (en)	1992-03-31
AU2706484A (en)	1984-10-25
DK167493B1 (da)	1993-11-08
GB2140800B (en)	1987-09-23
JPH0569817B2 (da)	1993-10-01
DE3414752C2 (da)	1993-03-25
IE840965L (en)	1984-10-18
SK278120B6 (en)	1996-02-07
JPH0687800A (ja)	1994-03-29
NZ221999A (en)	1988-11-29
LU88265I2 (da)	1994-02-03
IL71569A (en)	1987-10-30
NO159016B (no)	1988-08-15
CA1336004C (en)	1995-06-20
ATA129184A (de)	1989-11-15
US4992474A (en)	1991-02-12
SE8402188L (sv)	1984-10-19
DK158092D0 (da)	1992-12-30
IT1199112B (it)	1988-12-30
US5091422A (en)	1992-02-25
SG12289G (en)	1989-07-07
SE8402188D0 (sv)	1984-04-18
CY1482A (en)	1989-12-08
CA1335999C (en)	1995-06-20
CH661497A5 (fr)	1987-07-31
FI85011C (fi)	1992-02-25
DE19575029I2 (de)	2002-11-07
GR79925B (da)	1984-10-31
IE57237B1 (en)	1992-06-17
FR2545482B1 (fr)	1988-06-17
AT390611B (de)	1990-06-11
PH21574A (en)	1987-12-11
HU200160B (en)	1990-04-28
NL930066I2 (nl)	1993-10-01
GB2176476A (en)	1986-12-31
ES531722A0 (es)	1985-06-01
GB8612357D0 (en)	1986-06-25
NL188406C (nl)	1992-06-16
GB2176476B (en)	1987-12-31
PT78443B (en)	1986-08-28
DE3448338C2 (da)	1993-05-19
DE3448452C2 (de)	1994-01-05
ZW6584A1 (en)	1985-04-17

Publication	Publication Date	Title
DK201784D0 (da)	1984-04-18	Phenethanolaminderivater
BR8400004A (pt)	1984-07-31	Retroprojetor
BR8400552A (pt)	1984-09-18	Toca-fitas
ATA343284A (de)	1991-10-15	Raffrollo
DE3368175D1 (de)	1987-01-22	Rotobaler
AT387927B (de)	1989-04-10	Loetstation
AT377349B (de)	1985-03-11	Lusterbehang
ATA95483A (de)	1985-05-15	Waelzmuehle
FI830202A0 (fi)	1983-01-21	Hugg
DD255048A3 (de)	1988-03-23	Branddichtungsstopfbuchse
BR8405756A (pt)	1985-02-20	Artropodicidas
AT385002B (de)	1988-02-10	Geraeuschgedaempftes schienenrad
ATA312084A (de)	1990-07-15	Bandsaatschar
ATA224283A (de)	1984-06-15	Kronenstein
DD219060A3 (de)	1985-02-20	Absorptionswaermepumpe
DD232186A5 (de)	1986-01-22	Schaedlingsbekaempfungsmittel
BR8304310A (pt)	1985-03-19	Peteca
DD253926A3 (de)	1988-02-10	Bohrlocherweiterer
AR229549A1 (es)	1983-09-15	Ladrillo-teja
FI830577A0 (fi)	1983-02-21	Under fordon fastmonterat reservhjulsskydd
FI830876A0 (fi)	1983-03-16	Fuktskydd foer under skoetsel staoende kroppsdelar
BR8303916A (pt)	1985-03-05	Video-peca
BR6301363U (pt)	1985-04-30	Potenciostato-galvanostato
BR8303917A (pt)	1985-03-05	Tele-peca
BR6300060U (pt)	1983-09-20	Sonofletor

Legal Events

Date	Code	Title	Description
1993-11-08	B1	Patent granted (law 1993)
1994-09-05	CTFF	Application for supplementary protection certificate (spc) filed	Free format text: CA 1994 00008, 940704
1994-12-05	CTFF	Application for supplementary protection certificate (spc) filed	Free format text: CA 1994 00008, 940704
1997-02-10	CTFG	Supplementary protection certificate (spc) issued	Free format text: CA 1994 00008, 940704, EXPIRES: 20051025
2004-05-03	PUP	Patent expired