DK183291D0 - 25-OXOVITAMIN D2 DERIVATE INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLED VITAMIN D2 DERIVATES - Google Patents

25-OXOVITAMIN D2 DERIVATE INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLED VITAMIN D2 DERIVATES

Info

Publication number: DK183291D0
Authority: DK; Denmark
Prior art keywords: dihydroxyled; oxovitamin; 1alfa; derivate; derivates
Prior art date: 1983-05-09

Application number

DK911832A

Other languages

Danish (da)

Other versions

DK183291A (en

DK172733B1 (en

Inventor

Hector F Deluca

Heinrich K Schnoes

Rafael R Sicinski

Yoko Tanaka

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-05-09

Filing date

1991-11-07

Publication date

1991-11-07

1991-11-07 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1991-11-07 Publication of DK183291A publication Critical patent/DK183291A/en

1991-11-07 Publication of DK183291D0 publication Critical patent/DK183291D0/en

1999-06-21 Application granted granted Critical

1999-06-21 Publication of DK172733B1 publication Critical patent/DK172733B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Nutrition Science (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)

DK199101832A 1983-05-09 1991-11-07 25-oxovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives DK172733B1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US49286383A	1983-05-09	1983-05-09
US49286383		1983-05-09
US60732784A	1984-05-04	1984-05-04
US60732784		1984-05-04

Publications (3)

Publication Number	Publication Date
DK183291A DK183291A (en)	1991-11-07
DK183291D0 true DK183291D0 (en)	1991-11-07
DK172733B1 DK172733B1 (en)	1999-06-21

Family

ID=27050897

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK008685A DK171397B1 (en)	1983-05-09	1985-01-08	24-Epi-1alpha,25-dihydroxylated vitamin D2 derivatives, and preparations for pharmaceutical use which comprises these derivatives
DK198801845A DK172567B1 (en)	1983-05-09	1988-04-06	3,5-cyclovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives
DK199101832A DK172733B1 (en)	1983-05-09	1991-11-07	25-oxovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DK008685A DK171397B1 (en)	1983-05-09	1985-01-08	24-Epi-1alpha,25-dihydroxylated vitamin D2 derivatives, and preparations for pharmaceutical use which comprises these derivatives
DK198801845A DK172567B1 (en)	1983-05-09	1988-04-06	3,5-cyclovitamin D2 derivative intermediates for use in the preparation of 1alpha, 25-dihydroxylated vitamin D2 derivatives

Country Status (7)

Country	Link
JP (3)	JPH0651624B2 (en)
AU (1)	AU568549B2 (en)
CH (1)	CH665834A5 (en)
DE (4)	DE3448412C2 (en)
DK (3)	DK171397B1 (en)
NL (1)	NL193245C (en)
WO (1)	WO1984004527A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62500301A (en) *	1984-10-04	1987-02-05	ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン	24-Homovitamin D derivative
WO1986004333A1 (en) *	1985-01-17	1986-07-31	Wisconsin Alumni Research Foundation	Vitamin d derivatives and methods for preparing same
US5104864A (en) *	1988-08-02	1992-04-14	Bone Care International, Inc.	Method for treating and preventing loss of bone mass
CA1341408C (en) *	1988-08-02	2002-12-10	Charles W. Bishop	Method for treating and preventing loss of bone mass
US4973584A (en) *	1989-03-09	1990-11-27	Deluca Hector F	Novel 1α-hydroxyvitamin D2 epimer and derivatives
JP2645130B2 (en) *	1989-03-31	1997-08-25	日清製粉株式会社	Steroid derivatives
GB8914963D0 (en) *	1989-06-29	1989-08-23	Leo Pharm Prod Ltd	Chemical compounds
IN171426B (en) *	1990-02-14	1992-10-10	Wisconsin Alumni Res Found
US5795882A (en) *	1992-06-22	1998-08-18	Bone Care International, Inc.	Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
ES2170069T3 (en) *	1992-06-22	2002-08-01	Bone Care Int Inc	1-ALFA-HYDROXIPREVITAMINE D FOR ORAL ADMINISTRATION.
US5763429A (en)	1993-09-10	1998-06-09	Bone Care International, Inc.	Method of treating prostatic diseases using active vitamin D analogues
US6242434B1 (en)	1997-08-08	2001-06-05	Bone Care International, Inc.	24-hydroxyvitamin D, analogs and uses thereof
US6566353B2 (en)	1996-12-30	2003-05-20	Bone Care International, Inc.	Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en)	1996-12-30	2003-06-03	Bone Care International, Inc.	Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en)	1996-12-30	2003-01-07	Bone Care International, Inc.	Method of treating hyperproliferative diseases using active vitamin D analogues
PL336231A1 (en)	1997-02-13	2000-06-19	Bone Care International	System for aimed therapeutic delivery of vitamin d compounds
EP1301479A2 (en)	2000-07-18	2003-04-16	Bone Care International, Inc.	STABILIZED 1$g(a)-HYDROXY VITAMIN D
US7148211B2 (en)	2002-09-18	2006-12-12	Genzyme Corporation	Formulation for lipophilic agents
US7094775B2 (en)	2004-06-30	2006-08-22	Bone Care International, Llc	Method of treating breast cancer using a combination of vitamin D analogues and other agents
ES2759874T3 (en)	2008-03-12	2020-05-12	Opko Ireland Global Holdings Ltd	Stabilized 1,25-Dihydroxyvitamin D2 and its preparation method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4260549A (en) *	1979-05-21	1981-04-07	Wisconsin Alumni Research Foundation	Process for preparing 1α-hydroxylated compounds
US4267117A (en) *	1978-06-19	1981-05-12	The Upjohn Company	Compounds and process
US4269777A (en) *	1979-05-21	1981-05-26	Wisconsin Alumni Research Foundation	Isotopically labeled vitamin D derivatives and processes for preparing same

1984
- 1984-05-09 DE DE3448412A patent/DE3448412C2/de not_active Expired - Lifetime
- 1984-05-09 DE DE19843490215 patent/DE3490215T/en active Pending
- 1984-05-09 DE DE3490215A patent/DE3490215C2/de not_active Expired - Lifetime
- 1984-05-09 WO PCT/US1984/000714 patent/WO1984004527A1/en not_active Ceased
- 1984-05-09 CH CH145/85A patent/CH665834A5/en not_active IP Right Cessation
- 1984-05-09 NL NL8420137A patent/NL193245C/en not_active IP Right Cessation
- 1984-05-09 DE DE3448360A patent/DE3448360C2/de not_active Expired - Lifetime
- 1984-05-09 AU AU30115/84A patent/AU568549B2/en not_active Ceased
1985
- 1985-01-08 DK DK008685A patent/DK171397B1/en not_active IP Right Cessation
1988
- 1988-04-06 DK DK198801845A patent/DK172567B1/en not_active IP Right Cessation
1989
- 1989-12-26 JP JP1338023A patent/JPH0651624B2/en not_active Expired - Lifetime
- 1989-12-26 JP JP1338024A patent/JPH02288873A/en active Granted
- 1989-12-26 JP JP1338025A patent/JPH0610188B2/en not_active Expired - Fee Related
1991
- 1991-11-07 DK DK199101832A patent/DK172733B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK8685D0 (en)	1985-01-08
DK183291A (en)	1991-11-07
JPH02288829A (en)	1990-11-28
JPH02288873A (en)	1990-11-28
DE3490215T (en)	1985-05-15
CH665834A5 (en)	1988-06-15
DK184588D0 (en)	1988-04-06
AU568549B2 (en)	1988-01-07
DE3448412C2 (en)	1991-12-12
JPH0651624B2 (en)	1994-07-06
DE3490215C2 (en)	1991-07-25
DK8685A (en)	1985-01-08
DK172567B1 (en)	1999-01-18
NL193245C (en)	1999-04-02
NL8420137A (en)	1985-04-01
NL193245B (en)	1998-12-01
JPH0610188B2 (en)	1994-02-09
DK172733B1 (en)	1999-06-21
DE3448360C2 (en)	1991-10-02
JPH0339505B2 (en)	1991-06-14
JPH02288854A (en)	1990-11-28
DK184588A (en)	1988-04-06
WO1984004527A1 (en)	1984-11-22
DK171397B1 (en)	1996-10-14
AU3011584A (en)	1984-12-04

Publication	Publication Date	Title
DK183291D0 (en)	1991-11-07	25-OXOVITAMIN D2 DERIVATE INTERMEDIATES FOR USE IN THE PREPARATION OF 1ALFA, 25-DIHYDROXYLED VITAMIN D2 DERIVATES
ES507761A0 (en)	1982-09-01	PROCEDURE FOR THE PREPARATION OF NEW PYRIMIDINONES.
ES502546A0 (en)	1982-04-01	PROCEDURE FOR THE PREPARATION OF NEW N-ARILOXAZOLIDI-NONAS-2
ES507667A0 (en)	1983-01-01	PROCEDURE FOR THE PREPARATION OF 8-ARILALCOHIL-3-FENIL-3-NORTROPANOLES.
AR228468A1 (en)	1983-03-15	PROCEDURE FOR THE PREPARATION OF NEW IMIDAZOLYL-PHENYLAMIDINES
ES507635A0 (en)	1983-01-01	PROCEDURE FOR THE PREPARATION OF NEW PHENYLALCOHYLAMINS.
DK15681A (en)	1981-07-30	PROCEDURE FOR THE PREPARATION OF CYCLOHE EXCHANGE DERIVATIVES
ES502212A0 (en)	1982-09-01	PROCEDURE FOR THE PREPARATION OF N-DI-N-PROPIL-2,6-DINI-TRO-4-TRIFLUOROMETILANILINA
ES501464A0 (en)	1982-02-16	PROCEDURE FOR THE PREPARATION OF NEW FENILUREAS
DK15390D0 (en)	1990-01-19	CHOLESTA DIET DERIVATIVES AS INTERMEDIATE FOR USE IN THE PREPARATION OF HOMOVITAMIN-D3 DERIVATIVES
ES503975A0 (en)	1982-04-16	PROCEDURE FOR THE PREPARATION OF NEW FENILUREAS
AR225813A1 (en)	1982-04-30	PROCEDURE FOR THE PREPARATION OF 3-PICOLINE
DK56490A (en)	1990-03-05	HOMOCHOL STANDARD DERIVATIVES AS INTERMEDIATES FOR USE IN THE PREPARATION OF 26-HOMOVITAMIN D3 DERIVATIVES
ES500071A0 (en)	1982-01-01	PROCEDURE FOR THE PREPARATION OF NEW 2-NITRO-5-FENO- XIFENIL-OXAZOLES, -OXACINAS, -IMIDAZOLES, -PIRIMIDINAS O-TIAZO-LES
ES505095A0 (en)	1982-08-16	PROCEDURE FOR THE PREPARATION OF NEW PIRAZINES
AR228051A1 (en)	1983-01-14	PROCEDURE FOR THE PREPARATION OF NEW 2-PIPERIDINE-4-AMINO-6,7-DIMETOXIQUINAZOLINAS SUBSTITUTED
AR229350A1 (en)	1983-07-29	PROCEDURE FOR THE PREPARATION OF NEW GUANILAMIDINAS
DK451281A (en)	1982-04-14	PROCEDURE FOR THE PREPARATION OF CEPHALEXIN DERIVATIVES
IT8125157A0 (en)	1981-11-18	PROCEDURE FOR THE PREPARATION OF 2-AMINOETHANOLS.
DK537081A (en)	1982-06-06	PROCEDURE FOR THE PREPARATION OF ESTRA-4,9 DIET DERIVATIVES
MX152439A (en)	1985-07-15	PROCEDURE FOR THE PREPARATION OF 1-ACETOACETILAMINO-4-CLORO-2,5-DIMETOXIBENCENO
DK178586A (en)	1986-10-21	PROCEDURE FOR THE PREPARATION OF CASTING FORMS BY COMPRESSION OF FORMS
IT8026346A0 (en)	1980-12-02	PROCEDURE FOR THE PREPARATION OF DICUMYLPEROXIDE.
ES499860A0 (en)	1982-01-16	PROCEDURE FOR THE PREPARATION OF NEW 1-PHENILTHIO-2- PROPAR GILOXIETANOS
DK160583D0 (en)	1983-04-12	PROCEDURE FOR THE PREPARATION OF DIBENZINE DOLLAR DERIVATIVES

Legal Events

Date	Code	Title	Description
1999-06-21	B1	Patent granted (law 1993)
2004-02-02	PBP	Patent lapsed	Country of ref document: DK