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DK160992C - Antibiotiske makrolidforbindelser, praeparater indeholdende disse, fremgangmaader til fremstilling af forbindelserne samt fremgangsmaade til anvendelse af forbindelserne eller praeparaterne - Google Patents

Antibiotiske makrolidforbindelser, praeparater indeholdende disse, fremgangmaader til fremstilling af forbindelserne samt fremgangsmaade til anvendelse af forbindelserne eller praeparaterne

Info

Publication number
DK160992C
DK160992C DK196586A DK196586A DK160992C DK 160992 C DK160992 C DK 160992C DK 196586 A DK196586 A DK 196586A DK 196586 A DK196586 A DK 196586A DK 160992 C DK160992 C DK 160992C
Authority
DK
Denmark
Prior art keywords
compounds
procedures
preparations
preparation
antibiotic macrolide
Prior art date
Application number
DK196586A
Other languages
Danish (da)
English (en)
Other versions
DK196586D0 (da
DK160992B (da
DK196586A (da
Inventor
John Barrie Ward
Hazel Mary Noble
Neil Porter
Richard Alan Fletton
David Noble
Derek Ronald Sutherland
Michael Vincent John Ramsay
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858510944A external-priority patent/GB8510944D0/en
Priority claimed from GB858510942A external-priority patent/GB8510942D0/en
Priority claimed from GB858510943A external-priority patent/GB8510943D0/en
Priority claimed from GB868606103A external-priority patent/GB8606103D0/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK196586D0 publication Critical patent/DK196586D0/da
Publication of DK196586A publication Critical patent/DK196586A/da
Publication of DK160992B publication Critical patent/DK160992B/da
Application granted granted Critical
Publication of DK160992C publication Critical patent/DK160992C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/238—Cyclohexane rings substituted by two guanidine radicals, e.g. streptomycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK196586A 1985-04-30 1986-04-29 Antibiotiske makrolidforbindelser, praeparater indeholdende disse, fremgangmaader til fremstilling af forbindelserne samt fremgangsmaade til anvendelse af forbindelserne eller praeparaterne DK160992C (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB858510944A GB8510944D0 (en) 1985-04-30 1985-04-30 Chemical compounds
GB8510944 1985-04-30
GB8510943 1985-04-30
GB8510942 1985-04-30
GB858510942A GB8510942D0 (en) 1985-04-30 1985-04-30 Chemical compounds
GB858510943A GB8510943D0 (en) 1985-04-30 1985-04-30 Chemical compounds
GB868606103A GB8606103D0 (en) 1986-03-12 1986-03-12 Chemical compounds
GB8606103 1986-03-12

Publications (4)

Publication Number Publication Date
DK196586D0 DK196586D0 (da) 1986-04-29
DK196586A DK196586A (da) 1986-10-31
DK160992B DK160992B (da) 1991-05-13
DK160992C true DK160992C (da) 1991-11-11

Family

ID=27449656

Family Applications (1)

Application Number Title Priority Date Filing Date
DK196586A DK160992C (da) 1985-04-30 1986-04-29 Antibiotiske makrolidforbindelser, praeparater indeholdende disse, fremgangmaader til fremstilling af forbindelserne samt fremgangsmaade til anvendelse af forbindelserne eller praeparaterne

Country Status (25)

Country Link
US (1) US4978675A (lv)
JP (1) JPH0819132B2 (lv)
KR (1) KR930011282B1 (lv)
AT (1) AT397095B (lv)
AU (1) AU596586B2 (lv)
BE (1) BE904709A (lv)
CA (1) CA1335368C (lv)
CH (1) CH675124A5 (lv)
DE (1) DE3614549C2 (lv)
DK (1) DK160992C (lv)
ES (4) ES8802229A1 (lv)
FR (1) FR2587344B1 (lv)
GB (1) GB2176182B (lv)
GE (3) GEP19971046B (lv)
HU (1) HU200771B (lv)
IE (1) IE59070B1 (lv)
IL (1) IL78621A (lv)
LU (1) LU86412A1 (lv)
LV (2) LV10777B (lv)
NL (1) NL193420C (lv)
NZ (1) NZ215997A (lv)
PH (1) PH23386A (lv)
PT (1) PT82485B (lv)
RU (1) RU2004545C1 (lv)
SE (1) SE503571C2 (lv)

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GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
US5185456A (en) * 1986-03-12 1993-02-09 American Cyanamid Company Macrolide compounds
PH27415A (en) * 1986-03-12 1993-06-21 American Cyanamid Co Macrolide compounds
US5336789A (en) * 1986-03-12 1994-08-09 American Cyanamid Company Macrolide compounds
EP0238259B1 (en) * 1986-03-12 1993-09-29 American Cyanamid Company Macrolide compounds
ATE100810T1 (de) * 1986-03-12 1994-02-15 American Cyanamid Co Makrolid-verbindungen.
GB8606123D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
GB8613790D0 (en) * 1986-06-06 1986-07-09 Glaxo Group Ltd Chemical compounds
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
DE3750495T2 (de) * 1986-07-24 1995-02-23 Beecham Group Plc Milbemycin-Derivate mit parasitenabtötender Aktivität, ein Verfahren zu ihrer Herstellung und die sie enthaltenden Zusammensetzungen.
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ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
ES2055695T3 (es) * 1986-09-12 1994-09-01 American Cyanamid Co Derivados 23-desoxi de compuestos ll-f28249.
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
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US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
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EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
HU201327B (en) * 1987-09-11 1990-10-28 American Cyanamid Co Process for production of macrolide compositions
GB8721375D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721376D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721378D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721373D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721647D0 (en) * 1987-09-15 1987-10-21 Pfizer Ltd Antiparasitic agents
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
ATE87926T1 (de) * 1987-11-09 1993-04-15 Pfizer Ethylierte avermectine.
GB8726384D0 (en) * 1987-11-11 1987-12-16 Coopers Animal Health Veterinary treatment
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8801908D0 (en) * 1988-01-28 1988-02-24 Glaxo Group Ltd Chemical compounds
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
JP2629047B2 (ja) * 1988-05-10 1997-07-09 アメリカン・サイアナミツド・カンパニー マクロライド化合物
GB8811037D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
ES2052173T3 (es) * 1989-04-11 1994-07-01 Pfizer Composiciones inyectables que contienen 25-cyclohexil-avermectina b1.
NZ234802A (en) * 1989-08-14 1992-11-25 Merck & Co Inc Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds
US5055486A (en) * 1989-12-22 1991-10-08 American Cyanamid Company 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5290804A (en) * 1991-05-01 1994-03-01 Merck & Co., Inc. Anthelmintic milbemycin analogs of novel microorganisms
DK0535734T3 (da) * 1991-09-30 1999-08-09 Merck & Co Inc Langtidsvirkende injicerbare formuleringer indeholdende hydrogeneret castorolie
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
GB9402916D0 (en) * 1994-02-16 1994-04-06 Pfizer Ltd Antiparasitic agents
GB9408044D0 (en) * 1994-04-22 1994-06-15 Sod Conseils Rech Applic Conversion of ginkgolide c to ginkgolide b
DE19534366C2 (de) * 1995-09-15 2000-08-17 Asta Medica Ag Verfahren zur Herstellung von 2,3,4,6-Tetra-O-benzyl-D-glucopyranose und 2,3,4,6-Tetra-O-allyl-D-glucopyranose
DK0765879T3 (da) * 1995-09-29 2001-03-19 Sankyo Co 13-substituerede milbemycin 5-oximderivater, deres fremstilling og deres anvendelse over for insekter og andre skadedyr
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NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
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US4457920A (en) * 1981-09-03 1984-07-03 Merck & Co., Inc. 4a-Substituted avermectin compounds
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JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
DE3519834C2 (de) * 1984-06-05 1993-12-16 American Cyanamid Co Neue antibiotische Wirkstoffe, Verfahren zu ihrer Gewinnung und ihre Anwendung zur Bekämpfung von Infektionen bei Tieren und Pflanzen
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ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina

Also Published As

Publication number Publication date
GEP20001917B (en) 2000-01-05
HUT46012A (en) 1988-09-28
GEP19971046B (en) 1997-11-26
ES557517A0 (es) 1988-07-16
IL78621A (en) 1991-06-30
LU86412A1 (fr) 1986-11-05
SE8601998D0 (sv) 1986-04-29
DK196586D0 (da) 1986-04-29
LV10314A (lv) 1994-10-20
ES8900093A1 (es) 1988-12-01
PH23386A (en) 1989-07-26
KR930011282B1 (ko) 1993-11-29
ES8802522A1 (es) 1988-07-16
SE8601998L (sv) 1986-10-31
AU596586B2 (en) 1990-05-10
ES557774A0 (es) 1988-12-01
NL8601103A (nl) 1986-11-17
US4978675A (en) 1990-12-18
AT397095B (de) 1994-01-25
LV10777A (lv) 1995-08-20
IE59070B1 (en) 1993-12-15
DE3614549C2 (de) 1998-03-12
LV10777B (en) 1996-04-20
LV10314B (en) 1995-08-20
JPS61280496A (ja) 1986-12-11
ATA115486A (de) 1993-06-15
CH675124A5 (lv) 1990-08-31
FR2587344B1 (fr) 1991-04-05
NL193420B (nl) 1999-06-01
PT82485B (pt) 1988-03-03
KR860008205A (ko) 1986-11-14
ES8802229A1 (es) 1988-04-16
NZ215997A (en) 1989-06-28
DE3614549A1 (de) 1987-01-02
GB2176182A (en) 1986-12-17
IE861127L (en) 1986-10-30
BE904709A (fr) 1986-10-30
FR2587344A1 (fr) 1987-03-20
GEP19970833B (en) 1997-02-10
DK160992B (da) 1991-05-13
NL193420C (nl) 1999-10-04
GB2176182B (en) 1989-02-01
JPH0819132B2 (ja) 1996-02-28
AU5676786A (en) 1986-11-06
GB8610631D0 (en) 1986-06-04
HU200771B (en) 1990-08-28
RU2004545C1 (ru) 1993-12-15
IL78621A0 (en) 1986-08-31
SE503571C2 (sv) 1996-07-08
ES9000023A1 (es) 1990-05-01
PT82485A (en) 1986-05-01
CA1335368C (en) 1995-04-25
ES554444A0 (es) 1988-04-16
DK196586A (da) 1986-10-31
ES557851A0 (es) 1990-05-01

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