DK167800B1 - Fremgangsmaade samt indretning til injektion - Google Patents

Fremgangsmaade samt indretning til injektion Download PDF

Info

Publication number: DK167800B1
Authority: DK; Denmark
Prior art keywords: container; movable wall; injection; wall; solution
Prior art date: 1987-07-02

Application number

DK367988A

Other languages

Danish (da)

English (en)

Other versions

DK367988A (da

DK367988D0 (da

Inventor

Birger Hjertman

Anders Stroem

Ebba Florin-Robertson

Bo Ahlstrand

Linda Fryklund

Original Assignee

Kabi Pharmacia Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-02

Filing date

1988-07-01

Publication date

1993-12-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26659876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK167800(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-07-02 Priority claimed from SE8702735A external-priority patent/SE465065B/sv

1988-04-15 Priority claimed from SE8801405A external-priority patent/SE464797B/sv

1988-07-01 Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab

1988-07-01 Publication of DK367988D0 publication Critical patent/DK367988D0/da

1989-01-03 Publication of DK367988A publication Critical patent/DK367988A/da

1993-12-20 Application granted granted Critical

1993-12-20 Publication of DK167800B1 publication Critical patent/DK167800B1/da

Links

239000007924 injection Substances 0.000 title claims description 87
238000002347 injection Methods 0.000 title claims description 87
238000000034 method Methods 0.000 title claims description 11
239000000243 solution Substances 0.000 claims description 53
229940088679 drug related substance Drugs 0.000 claims description 29
239000007788 liquid Substances 0.000 claims description 28
239000000126 substance Substances 0.000 claims description 24
239000008186 active pharmaceutical agent Substances 0.000 claims description 21
239000012528 membrane Substances 0.000 claims description 18
239000003708 ampul Substances 0.000 claims description 16
239000008346 aqueous phase Substances 0.000 claims description 12
230000007246 mechanism Effects 0.000 claims description 10
239000007787 solid Substances 0.000 claims description 7
239000000203 mixture Substances 0.000 claims description 6
239000000839 emulsion Substances 0.000 claims description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
230000015556 catabolic process Effects 0.000 claims description 3
238000006731 degradation reaction Methods 0.000 claims description 3
239000002002 slurry Substances 0.000 claims description 3
230000008569 process Effects 0.000 claims description 2
230000000149 penetrating effect Effects 0.000 claims 1
239000012530 fluid Substances 0.000 description 7
239000003795 chemical substances by application Substances 0.000 description 6
239000000463 material Substances 0.000 description 6
238000002360 preparation method Methods 0.000 description 6
239000007791 liquid phase Substances 0.000 description 4
239000004033 plastic Substances 0.000 description 4
230000001681 protective effect Effects 0.000 description 4
230000009471 action Effects 0.000 description 3
210000002159 anterior chamber Anatomy 0.000 description 3
230000015572 biosynthetic process Effects 0.000 description 3
239000002775 capsule Substances 0.000 description 3
230000000694 effects Effects 0.000 description 3
238000005187 foaming Methods 0.000 description 3
229940088597 hormone Drugs 0.000 description 3
239000005556 hormone Substances 0.000 description 3
239000002184 metal Substances 0.000 description 3
230000000144 pharmacologic effect Effects 0.000 description 3
230000008859 change Effects 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
238000010276 construction Methods 0.000 description 2
238000006073 displacement reaction Methods 0.000 description 2
238000004090 dissolution Methods 0.000 description 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
210000000056 organ Anatomy 0.000 description 2
230000036961 partial effect Effects 0.000 description 2
229920001184 polypeptide Polymers 0.000 description 2
239000000843 powder Substances 0.000 description 2
238000003825 pressing Methods 0.000 description 2
102000004196 processed proteins & peptides Human genes 0.000 description 2
108090000765 processed proteins & peptides Proteins 0.000 description 2
102000004877 Insulin Human genes 0.000 description 1
108090001061 Insulin Proteins 0.000 description 1
102000014150 Interferons Human genes 0.000 description 1
108010050904 Interferons Proteins 0.000 description 1
206010028980 Neoplasm Diseases 0.000 description 1
230000002411 adverse Effects 0.000 description 1
238000004220 aggregation Methods 0.000 description 1
230000002776 aggregation Effects 0.000 description 1
239000011324 bead Substances 0.000 description 1
239000000470 constituent Substances 0.000 description 1
230000000881 depressing effect Effects 0.000 description 1
230000001627 detrimental effect Effects 0.000 description 1
206010012601 diabetes mellitus Diseases 0.000 description 1
230000003292 diminished effect Effects 0.000 description 1
239000003814 drug Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
230000014509 gene expression Effects 0.000 description 1
239000011521 glass Substances 0.000 description 1
229940125396 insulin Drugs 0.000 description 1
229940079322 interferon Drugs 0.000 description 1
238000010255 intramuscular injection Methods 0.000 description 1
239000007927 intramuscular injection Substances 0.000 description 1
239000002960 lipid emulsion Substances 0.000 description 1
230000010494 opalescence Effects 0.000 description 1
230000003204 osmotic effect Effects 0.000 description 1
239000002245 particle Substances 0.000 description 1
238000005192 partition Methods 0.000 description 1
239000002504 physiological saline solution Substances 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002829 reductive effect Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
230000035939 shock Effects 0.000 description 1
229910001220 stainless steel Inorganic materials 0.000 description 1
239000010935 stainless steel Substances 0.000 description 1
238000003860 storage Methods 0.000 description 1
238000010254 subcutaneous injection Methods 0.000 description 1
239000007929 subcutaneous injection Substances 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod

Landscapes

Health & Medical Sciences (AREA)
Vascular Medicine (AREA)
Engineering & Computer Science (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Polyesters Or Polycarbonates (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

DK367988A 1987-07-02 1988-07-01 Fremgangsmaade samt indretning til injektion DK167800B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8702735		1987-07-02
SE8702735A SE465065B (sv)	1987-07-02	1987-07-02	Saett och anordning foer beredning och injektion av en injektionloesning
SE8801405		1988-04-15
SE8801405A SE464797B (sv)	1988-04-15	1988-04-15	Anordning foer beredning av en injektionsloesning

Publications (3)

Publication Number	Publication Date
DK367988D0 DK367988D0 (da)	1988-07-01
DK367988A DK367988A (da)	1989-01-03
DK167800B1 true DK167800B1 (da)	1993-12-20

Family

ID=26659876

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK367988A DK167800B1 (da)	1987-07-02	1988-07-01	Fremgangsmaade samt indretning til injektion

Country Status (17)

Country	Link
US (1)	US4968299A (pt)
EP (1)	EP0298067B1 (pt)
JP (1)	JPH0661361B2 (pt)
AU (1)	AU613379B2 (pt)
BR (1)	BR8803170A (pt)
CA (1)	CA1310871C (pt)
DE (1)	DE3865756D1 (pt)
DK (1)	DK167800B1 (pt)
ES (1)	ES2026695T3 (pt)
FI (1)	FI92467C (pt)
GR (1)	GR3003027T3 (pt)
IL (1)	IL86799A (pt)
MX (1)	MX172551B (pt)
NO (1)	NO173001C (pt)
NZ (1)	NZ225181A (pt)
PT (1)	PT87794B (pt)
YU (1)	YU46917B (pt)

Families Citing this family (195)

* Cited by examiner, † Cited by third party
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SE9502957D0 (sv) *	1995-08-28	1995-08-28	Pharmacia Ab	Device for displacing a member in a container
EP0831947B1 (de)	1996-04-02	2002-09-18	Disetronic Licensing AG	Injektionsgerät
DE59609513D1 (de) *	1996-04-02	2002-09-05	Disetronic Licensing Ag	Injektionsgerät
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AU727081B2 (en)	1996-07-01	2000-11-30	Pharmacia & Upjohn Ab	Delivery device and method for its operation
DE59611288D1 (de) *	1996-07-05	2005-12-01	Tecpharma Licensing Ag	Injektionsgerät zum injizieren von flüssigkeit
WO1998001171A1 (de)	1996-07-05	1998-01-15	Disetronic Licensing Ag	Injektionsgerät zum injizieren von flüssigkeit
JP3949752B2 (ja) *	1996-07-29	2007-07-25	日本ケミカルリサーチ株式会社	薬剤溶解機構付注射器
DE19717107B4 (de)	1997-04-23	2005-06-23	Disetronic Licensing Ag	System aus Behältnis und Antriebsvorrichtung für einen Kolben, der in dem ein Medikamentfluid enthaltenden Behältnis gehalten ist
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SE9702776D0 (sv) *	1997-07-22	1997-07-22	Pharmacia & Upjohn Ab	Method of preparing pharmaceutical compositions
US6171276B1 (en)	1997-08-06	2001-01-09	Pharmacia & Upjohn Ab	Automated delivery device and method for its operation
DE19740187C1 (de) *	1997-09-12	1999-04-15	Disetronic Licensing Ag	Vorrichtung zur dosierten Ausschüttung eines injizierbaren Produkts
SE9703425D0 (sv)	1997-09-23	1997-09-23	Pharmacia & Upjohn Ab	Prefilled ampooules and manufacture thereof
US5971953A (en) *	1998-01-09	1999-10-26	Bachynsky; Nicholas	Dual chamber syringe apparatus
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ES2140328B1 (es) *	1997-12-04	2000-10-16	Perez Jose Manuel Prieto	Dispositivo aplicador para ampollas de sustancias terapeuticas inyectables.
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JP2951938B1 (ja) *	1998-03-19	1999-09-20	日本ケミカルリサーチ株式会社	薬剤溶解機構を内蔵した注射器
US6681475B2 (en)	1998-04-20	2004-01-27	Becton Dickinson And Company	Method of sealing a medical container with a plastic closure
US6378714B1 (en)	1998-04-20	2002-04-30	Becton Dickinson And Company	Transferset for vials and other medical containers
DE19822031C2 (de)	1998-05-15	2000-03-23	Disetronic Licensing Ag	Autoinjektionsgerät
DE19821934C1 (de)	1998-05-15	1999-11-11	Disetronic Licensing Ag	Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
DE19821933C1 (de)	1998-05-15	1999-11-11	Disetronic Licensing Ag	Vorrichtung zur Verabreichung eines injizierbaren Produkts
US6290679B1 (en)	1999-05-14	2001-09-18	Disetronic Licensing Ag	Device for metered administration of an injectable product
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JP4294868B2 (ja)	1998-07-27	2009-07-15	アンテアリーズファーマインコーポレイテッド	医療用注射器組立体用の注射補助プローブ
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- 1988-06-22 FI FI882981A patent/FI92467C/fi active IP Right Grant
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- 1988-06-28 ES ES198888850235T patent/ES2026695T3/es not_active Expired - Lifetime
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Also Published As

Publication number	Publication date
DE3865756D1 (de)	1991-11-28
AU1860788A (en)	1989-01-05
IL86799A0 (en)	1988-11-30
FI92467B (fi)	1994-08-15
NO173001B (no)	1993-07-05
BR8803170A (pt)	1989-01-10
IL86799A (en)	1993-03-15
FI882981A7 (fi)	1989-01-03
ES2026695T3 (es)	1992-05-01
FI882981A0 (fi)	1988-06-22
NZ225181A (en)	1991-09-25
PT87794A (pt)	1989-06-30
EP0298067A1 (en)	1989-01-04
YU46917B (sh)	1994-06-24
AU613379B2 (en)	1991-08-01
DK367988A (da)	1989-01-03
PT87794B (pt)	1993-09-30
NO882743D0 (no)	1988-06-21
JPH0661361B2 (ja)	1994-08-17
DK367988D0 (da)	1988-07-01
CA1310871C (en)	1992-12-01
US4968299A (en)	1990-11-06
NO173001C (no)	1993-10-13
MX172551B (es)	1993-01-03
FI92467C (fi)	1994-11-25
GR3003027T3 (en)	1993-02-17
JPS6480371A (en)	1989-03-27
EP0298067B1 (en)	1991-10-23
NO882743L (no)	1989-01-03
YU128488A (en)	1990-08-31

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Legal Events

Date	Code	Title	Description
1993-12-20	B1	Patent granted (law 1993)
2008-07-21	PUP	Patent expired