DK1555265T3 - 7-phenylpyrazolopyridin-forbindelser - Google Patents

7-phenylpyrazolopyridin-forbindelser

Info

Publication number: DK1555265T3
Authority: DK; Denmark
Prior art keywords: phenylpyrazolopyridin; compounds; compound; äwherein; tetrahydropyranyl
Prior art date: 2002-10-22

Application number

DK03758781T

Other languages

Danish (da)

English (en)

Inventor

Shigeki Hibi

Yorihisa Hoshino

Koichi Kikuchi

Kogyoku Shin

Yoshinori Takahashi

Masae Fujisawa

Hisashi Shibata

Mitsuhiro Ino

Original Assignee

Eisai R&D Man Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-22

Filing date

2003-10-22

Publication date

2009-06-22

2003-10-22 Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd

2009-06-22 Application granted granted Critical

2009-06-22 Publication of DK1555265T3 publication Critical patent/DK1555265T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Plural Heterocyclic Compounds (AREA)

DK03758781T 2002-10-22 2003-10-22 7-phenylpyrazolopyridin-forbindelser DK1555265T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2002306695		2002-10-22
US42107102P	2002-10-25	2002-10-25
PCT/JP2003/013490 WO2004037822A1 (ja)	2002-10-22	2003-10-22	７−フェニルピラゾロピリジン化合物

Publications (1)

Publication Number	Publication Date
DK1555265T3 true DK1555265T3 (da)	2009-06-22

Family

ID=32179072

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03758781T DK1555265T3 (da)	2002-10-22	2003-10-22	7-phenylpyrazolopyridin-forbindelser

Country Status (21)

Country	Link
US (2)	US7323569B2 (ja)
EP (1)	EP1555265B1 (ja)
JP (1)	JP4322211B2 (ja)
KR (1)	KR100984085B1 (ja)
AT (1)	ATE426600T1 (ja)
AU (1)	AU2003275589B2 (ja)
BR (1)	BRPI0313976B8 (ja)
CA (1)	CA2494574C (ja)
CY (1)	CY1110319T1 (ja)
DE (1)	DE60326869D1 (ja)
DK (1)	DK1555265T3 (ja)
ES (1)	ES2322143T3 (ja)
MX (1)	MXPA05002185A (ja)
NO (1)	NO331294B1 (ja)
NZ (1)	NZ538860A (ja)
PL (1)	PL213633B1 (ja)
PT (1)	PT1555265E (ja)
RU (1)	RU2327699C2 (ja)
SI (1)	SI1555265T1 (ja)
TW (1)	TWI283679B (ja)
WO (1)	WO2004037822A1 (ja)

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BRPI0313976B8 (pt) *	2002-10-22	2021-05-25	Eisai Co Ltd	compostos de 7-fenilpirazolopiridina e uso dos mesmos na preparação de agente terapêutico ou profilático para doenças associadas com o crf ou seus receptores
WO2005100354A1 (ja) *	2004-04-12	2005-10-27	Eisai R & D Management Co., Ltd.	ピラゾール縮合環誘導体の製造方法
CN102532180B (zh) *	2005-12-30	2016-06-29	安纳考尔医药公司	含硼的小分子
RU2357729C2 (ru) *	2007-05-21	2009-06-10	Эльвира Ивановна Белобородова	Способ лечения язвенной болезни двенадцатиперстной кишки, осложненной коморбидными тревожно-депрессивными расстройствами
MX2010004135A (es)	2007-10-18	2010-04-30	Eisai R&D Man Co Ltd	Metodo para producir un derivado en anillo fusionado a pirazol.
PL2266990T3 (pl)	2008-04-15	2013-03-29	Eisai R&D Man Co Ltd	ZWIĄZEK 3-FENYLOPIRAZOLO[5,1-b] TIAZOLOWY
WO2011043387A1 (ja) *	2009-10-08	2011-04-14	エーザイ・アール・アンド・ディー・マネジメント株式会社	ピラゾロオキサゾール化合物
AR078521A1 (es)	2009-10-08	2011-11-16	Eisai R&D Man Co Ltd	Compuesto pirazolotiazol
EP2869822B1 (en) *	2012-07-09	2016-09-14	Janssen Pharmaceutica, N.V.	Inhibitors of phosphodiesterase 10 enzyme
CN108218903B (zh) *	2015-08-14	2020-12-08	南京中硼联康医疗科技有限公司	L-bpa的制备方法

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BRPI0313976B8 (pt) *	2002-10-22	2021-05-25	Eisai Co Ltd	compostos de 7-fenilpirazolopiridina e uso dos mesmos na preparação de agente terapêutico ou profilático para doenças associadas com o crf ou seus receptores

2003
- 2003-10-22 BR BRPI0313976A patent/BRPI0313976B8/pt not_active IP Right Cessation
- 2003-10-22 EP EP03758781A patent/EP1555265B1/en not_active Expired - Lifetime
- 2003-10-22 NZ NZ538860A patent/NZ538860A/en not_active IP Right Cessation
- 2003-10-22 WO PCT/JP2003/013490 patent/WO2004037822A1/ja not_active Ceased
- 2003-10-22 CA CA2494574A patent/CA2494574C/en not_active Expired - Lifetime
- 2003-10-22 AU AU2003275589A patent/AU2003275589B2/en not_active Expired
- 2003-10-22 AT AT03758781T patent/ATE426600T1/de active
- 2003-10-22 JP JP2004546447A patent/JP4322211B2/ja not_active Expired - Lifetime
- 2003-10-22 SI SI200331567T patent/SI1555265T1/sl unknown
- 2003-10-22 TW TW092129327A patent/TWI283679B/zh not_active IP Right Cessation
- 2003-10-22 DE DE60326869T patent/DE60326869D1/de not_active Expired - Lifetime
- 2003-10-22 RU RU2005115504/04A patent/RU2327699C2/ru active
- 2003-10-22 DK DK03758781T patent/DK1555265T3/da active
- 2003-10-22 PL PL376132A patent/PL213633B1/pl unknown
- 2003-10-22 KR KR1020057006800A patent/KR100984085B1/ko not_active Expired - Fee Related
- 2003-10-22 PT PT03758781T patent/PT1555265E/pt unknown
- 2003-10-22 ES ES03758781T patent/ES2322143T3/es not_active Expired - Lifetime
- 2003-10-22 US US10/524,662 patent/US7323569B2/en not_active Expired - Lifetime
- 2003-10-22 MX MXPA05002185A patent/MXPA05002185A/es active IP Right Grant
2005
- 2005-05-20 NO NO20052443A patent/NO331294B1/no not_active IP Right Cessation
2007
- 2007-09-20 US US11/858,160 patent/US20080076943A1/en not_active Abandoned
2009
- 2009-06-12 CY CY20091100625T patent/CY1110319T1/el unknown

Also Published As

Publication number	Publication date
AU2003275589A1 (en)	2004-05-13
AU2003275589B2 (en)	2009-05-28
US7323569B2 (en)	2008-01-29
US20060235011A1 (en)	2006-10-19
BRPI0313976B1 (pt)	2018-12-26
EP1555265A4 (en)	2006-08-02
WO2004037822A1 (ja)	2004-05-06
CA2494574C (en)	2011-05-17
HK1081536A1 (zh)	2006-05-19
NO20052443L (no)	2005-07-22
EP1555265A1 (en)	2005-07-20
US20080076943A1 (en)	2008-03-27
BR0313976A (pt)	2005-07-19
CA2494574A1 (en)	2004-05-06
RU2327699C2 (ru)	2008-06-27
PT1555265E (pt)	2009-05-12
JPWO2004037822A1 (ja)	2006-02-23
SI1555265T1 (sl)	2009-06-30
NO331294B1 (no)	2011-11-21
MXPA05002185A (es)	2005-05-23
KR20050070069A (ko)	2005-07-05
NO20052443D0 (no)	2005-05-20
TWI283679B (en)	2007-07-11
ATE426600T1 (de)	2009-04-15
BRPI0313976B8 (pt)	2021-05-25
PL376132A1 (en)	2005-12-27
TW200427687A (en)	2004-12-16
KR100984085B1 (ko)	2010-09-30
PL213633B1 (pl)	2013-04-30
CY1110319T1 (el)	2015-01-14
RU2005115504A (ru)	2006-01-20
DE60326869D1 (de)	2009-05-07
JP4322211B2 (ja)	2009-08-26
NZ538860A (en)	2006-07-28
ES2322143T3 (es)	2009-06-17
EP1555265B1 (en)	2009-03-25

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