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DK1402025T3 - Kimære fager - Google Patents

Kimære fager

Info

Publication number
DK1402025T3
DK1402025T3 DK02743959T DK02743959T DK1402025T3 DK 1402025 T3 DK1402025 T3 DK 1402025T3 DK 02743959 T DK02743959 T DK 02743959T DK 02743959 T DK02743959 T DK 02743959T DK 1402025 T3 DK1402025 T3 DK 1402025T3
Authority
DK
Denmark
Prior art keywords
phages
protein
phage
helper
coat
Prior art date
Application number
DK02743959T
Other languages
English (en)
Inventor
Erwin Houtzager
Ton Logtenberg
Kruif Cornelis Adriaan De
Original Assignee
Crucell Holland Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP01202304A external-priority patent/EP1266963A1/en
Priority claimed from US09/882,621 external-priority patent/US7070926B2/en
Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv
Application granted granted Critical
Publication of DK1402025T3 publication Critical patent/DK1402025T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Holo Graphy (AREA)
DK02743959T 2001-06-15 2002-06-14 Kimære fager DK1402025T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202304A EP1266963A1 (en) 2001-06-15 2001-06-15 Chimaeric phages
US09/882,621 US7070926B2 (en) 2001-06-15 2001-06-15 Chimaeric phages

Publications (1)

Publication Number Publication Date
DK1402025T3 true DK1402025T3 (da) 2006-06-06

Family

ID=26076931

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02743959T DK1402025T3 (da) 2001-06-15 2002-06-14 Kimære fager

Country Status (10)

Country Link
US (2) US7329530B2 (da)
EP (1) EP1402025B1 (da)
AT (1) ATE317009T1 (da)
AU (1) AU2002345421B2 (da)
CA (1) CA2449071C (da)
DE (1) DE60209010T2 (da)
DK (1) DK1402025T3 (da)
ES (1) ES2257560T3 (da)
NZ (1) NZ529465A (da)
WO (1) WO2002103012A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1402025T3 (da) 2001-06-15 2006-06-06 Crucell Holland Bv Kimære fager
US7070926B2 (en) 2001-06-15 2006-07-04 Crucell Holland B.V. Chimaeric phages
WO2003052053A2 (en) * 2001-12-17 2003-06-26 Ribapharm Inc. Nucleoside libraries and compounds by mcc combinatorial strategies on solid support
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
ES2442615T5 (es) 2002-07-18 2023-03-16 Merus Nv Producción recombinante de mezclas de anticuerpos
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
EP1639009B1 (en) 2003-05-30 2013-02-27 Merus B.V. Fab library for the preparation of a mixture of antibodies
WO2005000894A2 (en) 2003-06-25 2005-01-06 Crucell Holland B.V. Binding molecules for the treatment of myeloid cell malignancies
PL2314620T3 (pl) 2004-05-27 2013-11-29 Crucell Holland Bv Sposób identyfikowania cząsteczek wiążących zdolnych do neutralizowania wirusa wścieklizny
JP4852046B2 (ja) * 2004-10-12 2012-01-11 クルセル ホランド ベー ヴェー 癌の治療及び検出に用いる結合分子
EP1812067B1 (en) 2004-11-11 2012-03-21 Crucell Holland B.V. Compositions against sars-coronavirus and uses thereof
CA2591665C (en) 2004-12-20 2015-05-05 Crucell Holland B.V. Binding molecules capable of neutralizing west nile virus and uses thereof
US20060235795A1 (en) * 2005-04-19 2006-10-19 Microsoft Corporation Secure network commercial transactions
CA2608058C (en) 2005-05-12 2013-09-10 Crucell Holland B.V. Host cell specific binding molecules capable of neutralizing viruses and uses thereof
AU2006290736B2 (en) 2005-09-15 2011-09-15 Crucell Holland B.V. Method for preparing immunoglobulin libraries
EP1963494B1 (en) * 2005-11-29 2014-10-08 The Trustees of The University of Pennsylvania Phage particle diagnostic reagents
US8227242B2 (en) * 2005-12-07 2012-07-24 Los Alamos National Security, Llc Plasmids and packaging cell lines for use in phage display
EP2027155B1 (en) 2006-06-06 2016-01-27 Crucell Holland B.V. Human binding molecules having killing activity against staphylococci and uses thereof
CN101460518B (zh) 2006-06-06 2012-08-22 克鲁塞尔荷兰公司 针对肠球菌和金黄色葡萄球菌具有杀伤活性的人结合分子及其应用
EP2450379B1 (en) 2006-09-07 2015-11-04 Crucell Holland B.V. Human binding molecules capable of neutralizing influenza virus H5N1 and uses thereof
CA2663388C (en) 2006-09-07 2017-01-17 Crucell Holland B.V. Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof
US9150849B2 (en) 2007-11-02 2015-10-06 The Scripps Research Institute Directed evolution using proteins comprising unnatural amino acids
SG176003A1 (en) 2009-05-11 2011-12-29 Crucell Holland Bv Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof
ES2608321T3 (es) 2011-07-14 2017-04-07 Janssen Vaccines & Prevention B.V. Moléculas de unión humanas capaces de neutralizar virus de la gripe A del grupo filogenético 1 y del grupo filogenético 2 y virus de la gripe B
CA2791109C (en) 2011-09-26 2021-02-16 Merus B.V. Generation of binding molecules
MY170407A (en) 2012-03-08 2019-07-27 Crucell Holland Bv Human binding molecules capable of binding to and neutralizing influenza b viruses and uses thereof
ES2740749T3 (es) 2012-04-20 2020-02-06 Merus Nv Métodos y medios para la producción de moléculas heterodiméricas similares a Ig
US11066460B2 (en) 2015-11-25 2021-07-20 Eli Lilly And Company Phage display vectors and methods of use
WO2020180971A1 (en) * 2019-03-04 2020-09-10 The Texas A&M University System Methods of making and utilizing amber-obligated phage display libraries

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9500851D0 (en) * 1995-01-17 1995-03-08 Bionvent International Ab Method of selecting specific bacteriophages
EP1266963A1 (en) 2001-06-15 2002-12-18 Crucell Holland B.V. Chimaeric phages
DK1402025T3 (da) * 2001-06-15 2006-06-06 Crucell Holland Bv Kimære fager
US7070926B2 (en) 2001-06-15 2006-07-04 Crucell Holland B.V. Chimaeric phages

Also Published As

Publication number Publication date
US7901919B2 (en) 2011-03-08
WO2002103012A1 (en) 2002-12-27
ATE317009T1 (de) 2006-02-15
EP1402025A1 (en) 2004-03-31
AU2002345421B2 (en) 2006-11-16
CA2449071C (en) 2008-12-16
US20050014261A1 (en) 2005-01-20
EP1402025B1 (en) 2006-02-01
DE60209010D1 (de) 2006-04-13
DE60209010T2 (de) 2006-09-28
ES2257560T3 (es) 2006-08-01
US20090017521A1 (en) 2009-01-15
CA2449071A1 (en) 2002-12-27
US7329530B2 (en) 2008-02-12
NZ529465A (en) 2005-05-27

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