[go: up one dir, main page]

DK1390042T3 - System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse - Google Patents

System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse

Info

Publication number
DK1390042T3
DK1390042T3 DK02738961T DK02738961T DK1390042T3 DK 1390042 T3 DK1390042 T3 DK 1390042T3 DK 02738961 T DK02738961 T DK 02738961T DK 02738961 T DK02738961 T DK 02738961T DK 1390042 T3 DK1390042 T3 DK 1390042T3
Authority
DK
Denmark
Prior art keywords
administering
drug
hormonal contraception
tetrahydroxylated estrogen
tetrahydroxylated
Prior art date
Application number
DK02738961T
Other languages
English (en)
Inventor
Christian Franz Holinka
Bennink Herman Jan Ti Coelingh
Evert Johannes Bunschoten
Original Assignee
Pantarhei Bioscience Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP01201945A external-priority patent/EP1293210B1/en
Application filed by Pantarhei Bioscience Bv filed Critical Pantarhei Bioscience Bv
Application granted granted Critical
Publication of DK1390042T3 publication Critical patent/DK1390042T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02738961T 2001-05-23 2002-05-23 System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse DK1390042T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP01201946 2001-05-23
EP01201947 2001-05-23
EP01201945A EP1293210B1 (en) 2001-05-23 2001-05-23 Means and method for hormonal contraception
EP01204377 2001-11-15
EP02075695 2002-02-21
PCT/NL2002/000331 WO2002094279A1 (en) 2001-05-23 2002-05-23 Drug delivery system comprising a tetrahidroxilated estrogen for use in hormonal contraception

Publications (1)

Publication Number Publication Date
DK1390042T3 true DK1390042T3 (da) 2008-03-31

Family

ID=27513107

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02738961T DK1390042T3 (da) 2001-05-23 2002-05-23 System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse

Country Status (12)

Country Link
US (1) US7732430B2 (da)
EP (1) EP1390042B1 (da)
CA (1) CA2448278C (da)
CY (2) CY1108093T1 (da)
DE (1) DE60223795T2 (da)
DK (1) DK1390042T3 (da)
ES (1) ES2296943T3 (da)
FR (1) FR21C1033I2 (da)
LU (1) LUC00213I2 (da)
NL (1) NL301115I2 (da)
PT (1) PT1390042E (da)
WO (1) WO2002094279A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60318092T2 (de) 2002-10-23 2008-11-27 Pantarhei Bioscience B.V. Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung
DE60332754D1 (de) 2002-11-08 2010-07-08 Pantarhei Bioscience Bv Synthese von oestetrol aus von oestron abgeleiteten steroiden
SI2714712T1 (sl) 2011-06-01 2016-11-30 Estetra S.P.R.L. Postopek za proizvodnjo intermediatov estetrola
CN103703014A (zh) 2011-06-01 2014-04-02 埃斯特拉公司 用于产生雌四醇中间体的方法
CA2842175C (en) 2011-07-19 2019-10-15 Herman Jan Tijmen Coelingh Bennink Tablet containing dehydroepiandrosterone (dhea)
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
US9579329B2 (en) * 2011-08-11 2017-02-28 Estetra S.P.R.L. Use of estetrol as emergency contraceptive
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
WO2015040051A1 (en) 2013-09-18 2015-03-26 Crystal Pharma, S.A.U. Process for the preparation of estetrol
NO3079671T3 (da) * 2013-12-12 2018-03-24
HUE054551T2 (hu) 2015-06-18 2021-09-28 Estetra Sprl Ösztetrolt tartalmazó, szájban diszpergálódó tabletta
MA44205B1 (fr) 2015-06-18 2021-04-30 Estetra Sprl Comprimé orodispersible comprenant estetrol
EP3310333B1 (en) 2015-06-18 2020-04-29 Estetra SPRL Orodispersible dosage unit containing an estetrol component
SMT201800232T1 (it) 2015-06-18 2018-07-17 Mithra Pharmaceuticals S A Unita' di dosaggio orodispersibile contenente un componente di estetrolo
KR102712911B1 (ko) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
EP4140489A1 (en) * 2018-02-07 2023-03-01 Estetra SRL Contraceptive composition with reduced cardiovascular effects
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US20250152604A1 (en) 2022-02-10 2025-05-15 Estetra Srl Contraceptive methods with scheduled bleeding effects
US12233074B2 (en) 2022-02-10 2025-02-25 Estetra Srl Contraceptive methods with improved pearl index
HUP2400151A1 (hu) 2024-02-28 2025-09-28 Richter Gedeon Nyrt Ösztetrol-monohidrát kristályosítási eljárás

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3440320A (en) 1964-06-18 1969-04-22 Mortimer D Sackler Chelated suppository and method of using same
US3797494A (en) 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
DE2336433A1 (de) 1973-07-13 1975-04-03 Schering Ag 1.3-oxygenierte 8 alpha-oestratriene
DE2336434A1 (de) 1973-07-13 1975-04-17 Schering Ag 1.3-oxygenierte 8 alpha-oestratriene
DE2426779A1 (de) 1974-05-31 1975-12-18 Schering Ag 1.3-oxygenierte 8 alpha-oestratriene
US4722941A (en) 1978-06-07 1988-02-02 Kali-Chemie Pharma Gmbh Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof
US4460372A (en) 1981-02-17 1984-07-17 Alza Corporation Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer
US4573996A (en) 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
US4624665A (en) 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
US4937238A (en) 1986-03-04 1990-06-26 The Board Of Regents Of The University Of Nebraska Prevention of mammary carcinoma
US4762717A (en) * 1986-03-21 1988-08-09 The General Hospital Corporation Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive
US5223261A (en) 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
US5043331A (en) 1989-06-15 1991-08-27 Orion-Yhtyma Oy Treatment of postmenopausal disorders
US5130137A (en) 1989-08-09 1992-07-14 The General Hospital Corporation Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use in treating benign ovarian secretory disorders
JPH04235171A (ja) 1990-07-26 1992-08-24 Sumitomo Chem Co Ltd スルホヒドロキサム酸誘導体、その製造法およびそれを有効成分とする除草剤
US5063507A (en) 1990-09-14 1991-11-05 Plains Cotton Cooperative Association Goods database employing electronic title or documentary-type title
US5340586A (en) 1991-04-12 1994-08-23 University Of Southern California Methods and formulations for use in treating oophorectomized women
US5340585A (en) 1991-04-12 1994-08-23 University Of Southern California Method and formulations for use in treating benign gynecological disorders
US5211952A (en) * 1991-04-12 1993-05-18 University Of Southern California Contraceptive methods and formulations for use therein
US5468736A (en) 1993-02-25 1995-11-21 The Medical College Of Hampton Road Hormone replacement therapy
US5895783A (en) 1993-07-16 1999-04-20 Schering Aktiengesellschaft Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
NL9301562A (nl) 1993-09-09 1995-04-03 Saturnus Ag Preparaat voor substitutietherapie.
DE4344405C2 (de) 1993-12-24 1995-12-07 Marika Dr Med Ehrlich Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption
WO1996003929A1 (en) 1994-08-04 1996-02-15 Biex, Inc. Method for prediction of premature delivery using estetrol (e4) as an indicator
DE4429374C1 (de) * 1994-08-12 1996-02-01 Jenapharm Gmbh Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente
EP0994718B1 (en) 1997-06-20 2005-08-17 Akzo Nobel N.V. Gonadotropin releasing hormone antagonist
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
US6214815B1 (en) * 1998-12-23 2001-04-10 Ortho-Mcneil Pharmaceuticals, Inc. Triphasic oral contraceptive
DE19917930A1 (de) 1999-04-15 2000-10-19 Schering Ag Ent-Steroide als selektiv wirksame Estrogene
JP2003527310A (ja) 1999-04-16 2003-09-16 イエナフアルム ゲーエムベーハー ウント ツェーオー. カーゲー エストロゲンを局部的に皮内投与するための医薬品組成物または化粧品組成物
WO2000073416A1 (en) 1999-05-28 2000-12-07 University Of Cincinnati Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
AU5984701A (en) 2000-05-12 2001-11-20 Univ Oregon Health & Science Method of treating immune pathologies with low dose estrogen
US6936599B2 (en) 2001-04-25 2005-08-30 The Regents Of The University Of California Estriol therapy for multiple sclerosis and other autoimmune diseases
EP1260225A1 (en) 2001-05-18 2002-11-27 Pantarhei Bioscience B.V. A pharmaceutical composition for use in hormone replacement therapy
ATE347365T1 (de) * 2001-11-15 2006-12-15 Pantarhei Bioscience Bv Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie

Also Published As

Publication number Publication date
PT1390042E (pt) 2008-03-10
LUC00213I1 (da) 2021-07-08
EP1390042B1 (en) 2007-11-28
CA2448278A1 (en) 2002-11-28
CY2021020I2 (el) 2021-12-31
EP1390042A1 (en) 2004-02-25
LUC00213I2 (da) 2021-10-29
CY2021020I1 (el) 2021-12-31
ES2296943T3 (es) 2008-05-01
CY1108093T1 (el) 2014-02-12
US20040198710A1 (en) 2004-10-07
DE60223795T2 (de) 2008-11-27
FR21C1033I2 (fr) 2022-04-22
DE60223795D1 (de) 2008-01-10
NL301115I2 (nl) 2021-10-25
FR21C1033I1 (fr) 2021-10-15
CA2448278C (en) 2010-06-08
NL301115I1 (da) 2021-07-14
WO2002094279A1 (en) 2002-11-28
US7732430B2 (en) 2010-06-08

Similar Documents

Publication Publication Date Title
DK1390042T3 (da) System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse
EP1068874A4 (en) MEDICINE DISPENSING DEVICE IN THE FORM OF AN INHALATOR
DK1221919T3 (da) Oftalmisk lægemiddeladministrationsanordning
DE60140462D1 (de) Darreichungsform zur hormonalen kontrazeption
ES2525087T8 (es) Polvos basados en fosfolípidos para administración de fármacos
NO20000735L (no) Legemiddel leveringsanordning for vedvarende frigivelse
DK1473003T3 (da) Lægemiddeladministrationsanordning
NO20025568D0 (no) Stabile farmasöytiske lösningsformuleringer til anvendelse for utmålte doseinhalatorer
DE69819205D1 (de) Orale pharmazeutische dosierungsform beruhend auf stossweiser freisetzung
NO20041315L (no) Medikamentavleveringssystem
NO20022970D0 (no) Hydrogel-drevet medikamentdoseringsform
NO20030627L (no) Hydrogel-drevet medikament doseringsform
DK1158992T3 (da) Anvendelse af xenon til fremstilling af et farmaceutisk præparat til behandling af neurointoksikationer
DE69935681D1 (de) Vorrichtungen zur Medikamentverabreichung
NO20014738L (no) Tolperisonholdig farmasöytisk preparat for oral administrering
ATE311173T1 (de) Neues selbstemulgierendes arzneistoffverabreichungssystem
IL137559A0 (en) Transdermal drug delivery system
IL139177A0 (en) Sustained release drug delivery system
NO20026055D0 (no) Farmasöytisk komponent omfattende human paratyroidhormon og farmasöytisk komponent for nasal administrering inneholdende komponentene
IS7383A (is) Skammtaform með stýrða lyflosun til inngjafar
AU5654701A (en) Drug delivery mask
EP1438087A4 (en) SYSTEM FOR THE ADMINISTRATION OF A MEDICAMENTAL DELIVERY DEVICE
SG97918A1 (en) A novel drug delivery system: formulation for fat-soluble drugs
NO20022013L (no) Innretninger for transdermal legemiddellevering
AU2002311675A1 (en) Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception