DK1390042T3 - System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse - Google Patents
System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelseInfo
- Publication number
- DK1390042T3 DK1390042T3 DK02738961T DK02738961T DK1390042T3 DK 1390042 T3 DK1390042 T3 DK 1390042T3 DK 02738961 T DK02738961 T DK 02738961T DK 02738961 T DK02738961 T DK 02738961T DK 1390042 T3 DK1390042 T3 DK 1390042T3
- Authority
- DK
- Denmark
- Prior art keywords
- administering
- drug
- hormonal contraception
- tetrahydroxylated estrogen
- tetrahydroxylated
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 229940011871 estrogen Drugs 0.000 title 1
- 239000000262 estrogen Substances 0.000 title 1
- 230000003054 hormonal effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01201946 | 2001-05-23 | ||
| EP01201947 | 2001-05-23 | ||
| EP01201945A EP1293210B1 (en) | 2001-05-23 | 2001-05-23 | Means and method for hormonal contraception |
| EP01204377 | 2001-11-15 | ||
| EP02075695 | 2002-02-21 | ||
| PCT/NL2002/000331 WO2002094279A1 (en) | 2001-05-23 | 2002-05-23 | Drug delivery system comprising a tetrahidroxilated estrogen for use in hormonal contraception |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1390042T3 true DK1390042T3 (da) | 2008-03-31 |
Family
ID=27513107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02738961T DK1390042T3 (da) | 2001-05-23 | 2002-05-23 | System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7732430B2 (da) |
| EP (1) | EP1390042B1 (da) |
| CA (1) | CA2448278C (da) |
| CY (2) | CY1108093T1 (da) |
| DE (1) | DE60223795T2 (da) |
| DK (1) | DK1390042T3 (da) |
| ES (1) | ES2296943T3 (da) |
| FR (1) | FR21C1033I2 (da) |
| LU (1) | LUC00213I2 (da) |
| NL (1) | NL301115I2 (da) |
| PT (1) | PT1390042E (da) |
| WO (1) | WO2002094279A1 (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60318092T2 (de) | 2002-10-23 | 2008-11-27 | Pantarhei Bioscience B.V. | Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung |
| DE60332754D1 (de) | 2002-11-08 | 2010-07-08 | Pantarhei Bioscience Bv | Synthese von oestetrol aus von oestron abgeleiteten steroiden |
| SI2714712T1 (sl) | 2011-06-01 | 2016-11-30 | Estetra S.P.R.L. | Postopek za proizvodnjo intermediatov estetrola |
| CN103703014A (zh) | 2011-06-01 | 2014-04-02 | 埃斯特拉公司 | 用于产生雌四醇中间体的方法 |
| CA2842175C (en) | 2011-07-19 | 2019-10-15 | Herman Jan Tijmen Coelingh Bennink | Tablet containing dehydroepiandrosterone (dhea) |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| US9579329B2 (en) * | 2011-08-11 | 2017-02-28 | Estetra S.P.R.L. | Use of estetrol as emergency contraceptive |
| WO2013034780A2 (en) | 2012-12-20 | 2013-03-14 | Crystal Pharma, S.A.U. | Process for the preparation of estetrol and related compounds |
| WO2015040051A1 (en) | 2013-09-18 | 2015-03-26 | Crystal Pharma, S.A.U. | Process for the preparation of estetrol |
| NO3079671T3 (da) * | 2013-12-12 | 2018-03-24 | ||
| HUE054551T2 (hu) | 2015-06-18 | 2021-09-28 | Estetra Sprl | Ösztetrolt tartalmazó, szájban diszpergálódó tabletta |
| MA44205B1 (fr) | 2015-06-18 | 2021-04-30 | Estetra Sprl | Comprimé orodispersible comprenant estetrol |
| EP3310333B1 (en) | 2015-06-18 | 2020-04-29 | Estetra SPRL | Orodispersible dosage unit containing an estetrol component |
| SMT201800232T1 (it) | 2015-06-18 | 2018-07-17 | Mithra Pharmaceuticals S A | Unita' di dosaggio orodispersibile contenente un componente di estetrolo |
| KR102712911B1 (ko) | 2016-08-05 | 2024-10-04 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
| EP4140489A1 (en) * | 2018-02-07 | 2023-03-01 | Estetra SRL | Contraceptive composition with reduced cardiovascular effects |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| HU231240B1 (hu) | 2019-09-03 | 2022-04-28 | Richter Gedeon Nyrt. | Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| US20250152604A1 (en) | 2022-02-10 | 2025-05-15 | Estetra Srl | Contraceptive methods with scheduled bleeding effects |
| US12233074B2 (en) | 2022-02-10 | 2025-02-25 | Estetra Srl | Contraceptive methods with improved pearl index |
| HUP2400151A1 (hu) | 2024-02-28 | 2025-09-28 | Richter Gedeon Nyrt | Ösztetrol-monohidrát kristályosítási eljárás |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3440320A (en) | 1964-06-18 | 1969-04-22 | Mortimer D Sackler | Chelated suppository and method of using same |
| US3797494A (en) | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
| DE2336433A1 (de) | 1973-07-13 | 1975-04-03 | Schering Ag | 1.3-oxygenierte 8 alpha-oestratriene |
| DE2336434A1 (de) | 1973-07-13 | 1975-04-17 | Schering Ag | 1.3-oxygenierte 8 alpha-oestratriene |
| DE2426779A1 (de) | 1974-05-31 | 1975-12-18 | Schering Ag | 1.3-oxygenierte 8 alpha-oestratriene |
| US4722941A (en) | 1978-06-07 | 1988-02-02 | Kali-Chemie Pharma Gmbh | Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof |
| US4460372A (en) | 1981-02-17 | 1984-07-17 | Alza Corporation | Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer |
| US4573996A (en) | 1984-01-03 | 1986-03-04 | Jonergin, Inc. | Device for the administration of an active agent to the skin or mucosa |
| US4624665A (en) | 1984-10-01 | 1986-11-25 | Biotek, Inc. | Method of transdermal drug delivery |
| US4937238A (en) | 1986-03-04 | 1990-06-26 | The Board Of Regents Of The University Of Nebraska | Prevention of mammary carcinoma |
| US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
| US5223261A (en) | 1988-02-26 | 1993-06-29 | Riker Laboratories, Inc. | Transdermal estradiol delivery system |
| US5043331A (en) | 1989-06-15 | 1991-08-27 | Orion-Yhtyma Oy | Treatment of postmenopausal disorders |
| US5130137A (en) | 1989-08-09 | 1992-07-14 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use in treating benign ovarian secretory disorders |
| JPH04235171A (ja) | 1990-07-26 | 1992-08-24 | Sumitomo Chem Co Ltd | スルホヒドロキサム酸誘導体、その製造法およびそれを有効成分とする除草剤 |
| US5063507A (en) | 1990-09-14 | 1991-11-05 | Plains Cotton Cooperative Association | Goods database employing electronic title or documentary-type title |
| US5340586A (en) | 1991-04-12 | 1994-08-23 | University Of Southern California | Methods and formulations for use in treating oophorectomized women |
| US5340585A (en) | 1991-04-12 | 1994-08-23 | University Of Southern California | Method and formulations for use in treating benign gynecological disorders |
| US5211952A (en) * | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
| US5468736A (en) | 1993-02-25 | 1995-11-21 | The Medical College Of Hampton Road | Hormone replacement therapy |
| US5895783A (en) | 1993-07-16 | 1999-04-20 | Schering Aktiengesellschaft | Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor |
| NL9301562A (nl) | 1993-09-09 | 1995-04-03 | Saturnus Ag | Preparaat voor substitutietherapie. |
| DE4344405C2 (de) | 1993-12-24 | 1995-12-07 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption |
| WO1996003929A1 (en) | 1994-08-04 | 1996-02-15 | Biex, Inc. | Method for prediction of premature delivery using estetrol (e4) as an indicator |
| DE4429374C1 (de) * | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| EP0994718B1 (en) | 1997-06-20 | 2005-08-17 | Akzo Nobel N.V. | Gonadotropin releasing hormone antagonist |
| DE19739916C2 (de) * | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen |
| US6214815B1 (en) * | 1998-12-23 | 2001-04-10 | Ortho-Mcneil Pharmaceuticals, Inc. | Triphasic oral contraceptive |
| DE19917930A1 (de) | 1999-04-15 | 2000-10-19 | Schering Ag | Ent-Steroide als selektiv wirksame Estrogene |
| JP2003527310A (ja) | 1999-04-16 | 2003-09-16 | イエナフアルム ゲーエムベーハー ウント ツェーオー. カーゲー | エストロゲンを局部的に皮内投与するための医薬品組成物または化粧品組成物 |
| WO2000073416A1 (en) | 1999-05-28 | 2000-12-07 | University Of Cincinnati | Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use |
| WO2001030356A1 (fr) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation |
| AU5984701A (en) | 2000-05-12 | 2001-11-20 | Univ Oregon Health & Science | Method of treating immune pathologies with low dose estrogen |
| US6936599B2 (en) | 2001-04-25 | 2005-08-30 | The Regents Of The University Of California | Estriol therapy for multiple sclerosis and other autoimmune diseases |
| EP1260225A1 (en) | 2001-05-18 | 2002-11-27 | Pantarhei Bioscience B.V. | A pharmaceutical composition for use in hormone replacement therapy |
| ATE347365T1 (de) * | 2001-11-15 | 2006-12-15 | Pantarhei Bioscience Bv | Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie |
-
2002
- 2002-05-23 EP EP02738961A patent/EP1390042B1/en not_active Expired - Lifetime
- 2002-05-23 US US10/478,365 patent/US7732430B2/en not_active Expired - Lifetime
- 2002-05-23 PT PT02738961T patent/PT1390042E/pt unknown
- 2002-05-23 CA CA2448278A patent/CA2448278C/en not_active Expired - Lifetime
- 2002-05-23 DK DK02738961T patent/DK1390042T3/da active
- 2002-05-23 DE DE60223795T patent/DE60223795T2/de not_active Expired - Lifetime
- 2002-05-23 WO PCT/NL2002/000331 patent/WO2002094279A1/en not_active Ceased
- 2002-05-23 ES ES02738961T patent/ES2296943T3/es not_active Expired - Lifetime
-
2008
- 2008-02-04 CY CY20081100136T patent/CY1108093T1/el unknown
-
2021
- 2021-07-07 NL NL301115C patent/NL301115I2/nl unknown
- 2021-07-08 LU LUC00213 patent/LUC00213I2/en unknown
- 2021-07-26 CY CY2021020C patent/CY2021020I1/el unknown
- 2021-07-27 FR FR21C1033C patent/FR21C1033I2/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PT1390042E (pt) | 2008-03-10 |
| LUC00213I1 (da) | 2021-07-08 |
| EP1390042B1 (en) | 2007-11-28 |
| CA2448278A1 (en) | 2002-11-28 |
| CY2021020I2 (el) | 2021-12-31 |
| EP1390042A1 (en) | 2004-02-25 |
| LUC00213I2 (da) | 2021-10-29 |
| CY2021020I1 (el) | 2021-12-31 |
| ES2296943T3 (es) | 2008-05-01 |
| CY1108093T1 (el) | 2014-02-12 |
| US20040198710A1 (en) | 2004-10-07 |
| DE60223795T2 (de) | 2008-11-27 |
| FR21C1033I2 (fr) | 2022-04-22 |
| DE60223795D1 (de) | 2008-01-10 |
| NL301115I2 (nl) | 2021-10-25 |
| FR21C1033I1 (fr) | 2021-10-15 |
| CA2448278C (en) | 2010-06-08 |
| NL301115I1 (da) | 2021-07-14 |
| WO2002094279A1 (en) | 2002-11-28 |
| US7732430B2 (en) | 2010-06-08 |
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