|
US5648254A
(en)
*
|
1988-01-15 |
1997-07-15 |
Zymogenetics, Inc. |
Co-expression in eukaryotic cells
|
|
US5037743A
(en)
*
|
1988-08-05 |
1991-08-06 |
Zymogenetics, Inc. |
BAR1 secretion signal
|
|
US6210948B1
(en)
|
1992-06-09 |
2001-04-03 |
The University Of British Columbia |
Expression and secretion of heterologous polypeptides from caulobacter
|
|
US5914254A
(en)
*
|
1993-08-02 |
1999-06-22 |
Celtrix Pharmaceuticals, Inc. |
Expression of fusion polypeptides transported out of the cytoplasm without leader sequences
|
|
US5563046A
(en)
*
|
1993-08-02 |
1996-10-08 |
Celtrix Pharmaceuticals, Inc. |
Fusion polypeptides and proteins
|
|
US6214794B1
(en)
|
1994-12-02 |
2001-04-10 |
The Johns Hopkins University School Of Medicine |
Method of using hedgehog polypeptides to regulate neuronal cell growth
|
|
US6911528B1
(en)
|
1994-12-02 |
2005-06-28 |
The Johns Hopkins University School Of Medicine |
Hedgehog-derived polypeptides
|
|
US6057091A
(en)
*
|
1994-12-02 |
2000-05-02 |
The Johns Hopkins University School Of Medicine |
Method of identifying compounds affecting hedgehog cholesterol transfer
|
|
US6281332B1
(en)
*
|
1994-12-02 |
2001-08-28 |
The Johns Hopkins University School Of Medicine |
Hedgehog-derived polypeptides
|
|
JPH1075774A
(ja)
*
|
1996-05-31 |
1998-03-24 |
Akzo Nobel Nv |
パスツレラ科の弱毒化rtx産生細菌
|
|
KR100611063B1
(ko)
|
1996-10-16 |
2006-08-09 |
지모제넥틱스, 인코포레이티드 |
섬유아세포 성장인자 상동체
|
|
WO1998023763A1
(en)
*
|
1996-11-29 |
1998-06-04 |
The General Hospital Corporation |
Heterologous antigens in live cell v. cholerae strains
|
|
CA2284733C
(en)
|
1997-03-24 |
2010-10-26 |
Zymogenetics, Inc. |
Motilin homologs
|
|
CA2331199C
(en)
|
1998-06-10 |
2012-10-23 |
Markus Sakari Kauppinen |
Isolated mannanases for use in treating cellulosic or synthetic fibers
|
|
EA201001190A1
(ru)
|
1998-09-23 |
2011-04-29 |
Займодженетикс, Инк. |
Выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков
|
|
ES2312223T3
(es)
|
1998-12-07 |
2009-02-16 |
Zymogenetics, Inc. |
Zvegf3 homologo de factor de crecimiento.
|
|
DK1642973T3
(da)
|
1999-01-07 |
2009-11-02 |
Zymogenetics Inc |
Terapeutisk anvendelser af BR43X2-oplöselige receptorer
|
|
US7833529B1
(en)
|
1999-01-07 |
2010-11-16 |
Zymogenetics, Inc. |
Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
|
|
CA2261186A1
(en)
|
1999-02-19 |
2000-08-19 |
University Of British Columbia |
Expression and secretion of heterologous polypeptides from freshwater caulobacter
|
|
BR0008772B1
(pt)
|
1999-03-09 |
2011-11-01 |
|
vetor de expressão, célula bacteriana ou fúngica cultivada, processos para expandir in vitro células hematopoiéticas e progenitores de células hematopoiéticas, e para detectar a presença de rna de ligando zalfa11 e de ligando zalfa 11 in vitro em uma amostra biológica.
|
|
US6664386B1
(en)
|
1999-04-08 |
2003-12-16 |
The Research Foundation Of State University Of New York |
System for efficient secretion of recombinant proteins
|
|
DE60034564T2
(de)
|
1999-07-07 |
2007-12-27 |
Zymogenetics, Inc., Seattle |
Menschlicher cytokinrezeptor
|
|
WO2001044289A2
(en)
*
|
1999-12-17 |
2001-06-21 |
University Of Guelph Office Of The Vice President Of Research |
Modified leukotoxin gene and protein
|
|
ATE459716T1
(de)
|
1999-12-23 |
2010-03-15 |
Zymogenetics Inc |
Zytokin zcyt018
|
|
AU2001253127A1
(en)
|
2000-04-05 |
2001-10-23 |
Zymogenetics Inc. |
Soluble zalpha11 cytokine receptors
|
|
EP2258725A3
(en)
|
2000-06-26 |
2014-09-17 |
ZymoGenetics, L.L.C. |
Cytokine receptor zcytor17
|
|
US7863020B2
(en)
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
|
US7795002B2
(en)
*
|
2000-06-28 |
2010-09-14 |
Glycofi, Inc. |
Production of galactosylated glycoproteins in lower eukaryotes
|
|
CA2413258C
(en)
|
2000-06-30 |
2012-01-03 |
Zymogenetics, Inc. |
Interferon-like protein zcyto21
|
|
EP1736545A3
(en)
|
2000-08-08 |
2007-03-28 |
ZymoGenetics, Inc. |
Soluble zcytor 11 cytokine receptors
|
|
KR100447530B1
(ko)
*
|
2001-08-14 |
2004-09-08 |
한국과학기술원 |
OmpF를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법
|
|
AU2002347426B2
(en)
|
2001-10-15 |
2007-05-10 |
Engeneic Molecular Delivery Pty Ltd |
Intact minicells as vectors for DNA transfer and gene therapy in vitro and in vivo
|
|
EP2130919A1
(en)
|
2001-11-05 |
2009-12-09 |
ZymoGenetics, Inc. |
IL-21 antagonists
|
|
US7087418B2
(en)
*
|
2001-12-19 |
2006-08-08 |
Bristol-Myers Squibb Company |
Pichia pastoris formate dehydrogenase and uses therefor
|
|
DE60333963D1
(de)
|
2002-01-18 |
2010-10-07 |
Zymogenetics Inc |
Zytokin Ligand zur Behandlung von Asthma und Atemwegsüberreaktivität
|
|
ATE547430T1
(de)
|
2002-01-18 |
2012-03-15 |
Zymogenetics Inc |
Multimere des cytokinrezeptors zcytor17
|
|
RU2004133765A
(ru)
|
2002-04-19 |
2005-06-27 |
ЗАЙМОДЖЕНЕТИКС Инк. (US) |
Рецептор цитокина
|
|
EP1531850B1
(en)
|
2002-06-07 |
2012-02-22 |
ZymoGenetics, Inc. |
Use of IL-21 and monoclonal antibody for treating solid cancers
|
|
WO2004078965A1
(ja)
*
|
2003-03-05 |
2004-09-16 |
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute |
大腸菌における異種蛋白質の製造方法
|
|
US20040241677A1
(en)
*
|
2003-05-29 |
2004-12-02 |
Lin Jeffrey S |
Techniques for automated diagnosis of cell-borne anomalies with digital optical microscope
|
|
ES2296423B1
(es)
*
|
2003-07-31 |
2009-03-16 |
Consejo Sup. Investig. Cientificas |
Construccion de adn para la produccion de proteinas de fusion dimericas y sus aplicaciones.
|
|
CA2534907C
(en)
|
2003-08-07 |
2014-04-29 |
Zymogenetics, Inc. |
Homogeneous preparations of il-28 and il-29
|
|
EP2087905A2
(en)
|
2003-08-08 |
2009-08-12 |
Novo Nordisk A/S |
Interleukin-20 for treating and diagnosing conditions associated with neovascularisation
|
|
CN102516386A
(zh)
|
2003-10-10 |
2012-06-27 |
诺沃挪第克公司 |
Il-21衍生物
|
|
EP2641611A3
(en)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Combination therapy
|
|
PL1694361T3
(pl)
|
2003-12-09 |
2011-08-31 |
Engeneic Molecular Delivery Pty Ltd |
Ukierunkowane dostarczanie genów do niefagocytujących komórek ssaczych z zastosowaniem nienaruszonych minikomórek pochodzących od bakterii
|
|
US7381794B2
(en)
|
2004-03-08 |
2008-06-03 |
Zymogenetics, Inc. |
Dimeric fusion proteins and materials and methods for producing them
|
|
AU2005266892B2
(en)
|
2004-07-29 |
2011-03-03 |
Bristol-Myers Squibb Company |
Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
|
|
EP1781784A2
(en)
|
2004-08-02 |
2007-05-09 |
BASF Plant Science GmbH |
Method for isolation of transcription termination sequences
|
|
EP2386640B1
(en)
|
2004-08-26 |
2015-01-28 |
EnGeneIC Molecular Delivery Pty Ltd |
Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells
|
|
WO2006086396A2
(en)
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
|
|
EP3683230A1
(en)
|
2005-05-12 |
2020-07-22 |
ZymoGenetics, Inc. |
Compositions and methods for modulating immune responses
|
|
US7393667B2
(en)
*
|
2005-05-31 |
2008-07-01 |
Bristol-Myers Squibb Company |
Stereoselective reduction process for the preparation of pyrrolotriazine compounds
|
|
AU2006278229B2
(en)
*
|
2005-08-09 |
2011-10-27 |
Ares Trading S.A. |
Methods for treating B-cell malignancies using TACI-Ig fusion molecule
|
|
JP5118037B2
(ja)
|
2005-08-09 |
2013-01-16 |
ザイモジェネティクス, インコーポレイテッド |
Taci融合分子を用いた異常細胞増殖の処置及び予防のための方法
|
|
UA98462C2
(ru)
*
|
2006-05-15 |
2012-05-25 |
Арес Трейдинг С.А. |
Способы лечения аутоиммунных заболеваний с использованием слитой молекулы taci-ig
|
|
CA2658058C
(en)
|
2006-06-23 |
2016-08-23 |
Engeneic Molecular Delivery Pty Ltd. |
Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
|
|
US20080124355A1
(en)
|
2006-09-22 |
2008-05-29 |
David Gordon Bermudes |
Live bacterial vaccines for viral infection prophylaxis or treatment
|
|
US8318664B2
(en)
|
2007-05-31 |
2012-11-27 |
Alize Pharma Sas |
Unacylated ghrelin fragments as therapeutic agent in the treatment of obesity
|
|
CN101678084B
(zh)
*
|
2007-05-31 |
2015-01-21 |
阿利兹药物股份有限公司 |
未酰基化的生长素释放肽作为治疗代谢紊乱中的治疗剂
|
|
CA2971794C
(en)
|
2007-10-04 |
2020-03-24 |
Zymogenetics, Inc. |
B7 family member zb7h6 and related compositions and methods
|
|
CA2706550C
(en)
|
2007-11-21 |
2021-12-14 |
Roskilde Universitet |
Polypeptides comprising an ice-binding activity
|
|
EP2231702A1
(en)
*
|
2007-12-21 |
2010-09-29 |
Ifxa A/s |
Protease inhibitor
|
|
NZ600205A
(en)
*
|
2008-01-25 |
2013-12-20 |
Univ Aarhus |
Selective exosite inhibition of papp-a activity against igfbp-4
|
|
ES2456296T3
(es)
|
2008-03-27 |
2014-04-21 |
Zymogenetics, Inc. |
Composiciones y procedimientos para inhibir PDGFR beta y VEGF-A
|
|
US8658766B2
(en)
|
2008-06-27 |
2014-02-25 |
Zymogenetics, Inc. |
Soluble hybrid Fcγ receptors and related methods
|
|
CA2733425A1
(en)
|
2008-08-06 |
2010-02-11 |
Emergent Product Development Uk Limited |
Vaccines against clostridium difficile and methods of use
|
|
US8647642B2
(en)
|
2008-09-18 |
2014-02-11 |
Aviex Technologies, Llc |
Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
|
|
US8241623B1
(en)
|
2009-02-09 |
2012-08-14 |
David Bermudes |
Protease sensitivity expression system
|
|
US9597379B1
(en)
|
2010-02-09 |
2017-03-21 |
David Gordon Bermudes |
Protease inhibitor combination with therapeutic proteins including antibodies
|
|
US8771669B1
(en)
|
2010-02-09 |
2014-07-08 |
David Gordon Bermudes |
Immunization and/or treatment of parasites and infectious agents by live bacteria
|
|
US8524220B1
(en)
|
2010-02-09 |
2013-09-03 |
David Gordon Bermudes |
Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria
|
|
WO2011156356A1
(en)
|
2010-06-09 |
2011-12-15 |
Zymogenetics, Inc. |
Dimeric vstm3 fusion proteins and related compositions and methods
|
|
WO2012106281A2
(en)
|
2011-01-31 |
2012-08-09 |
The General Hospital Corporation |
Multimodal trail molecules and uses in cellular therapies
|
|
EP2583975A1
(en)
*
|
2011-10-21 |
2013-04-24 |
Heinrich-Heine-Universität Düsseldorf |
Agents and methods for the expression and secretion of peptides and proteins
|
|
CA3156904A1
(en)
|
2012-02-01 |
2013-08-08 |
Synthetic Genomics, Inc. |
Materials and methods for the synthesis of error-minimized nucleic acid molecules
|
|
US9862932B2
(en)
|
2012-07-24 |
2018-01-09 |
The General Hospital Corporation |
Oncolytic virus therapy for resistant tumors
|
|
WO2014035474A1
(en)
|
2012-08-30 |
2014-03-06 |
The General Hospital Corporation |
Compositions and methods for treating cancer
|
|
JP6352920B2
(ja)
|
2012-09-04 |
2018-07-04 |
セレクティス |
多重鎖キメラ抗原受容体およびその使用
|
|
US9593339B1
(en)
|
2013-02-14 |
2017-03-14 |
David Gordon Bermudes |
Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
|
|
WO2014175164A1
(ja)
*
|
2013-04-25 |
2014-10-30 |
株式会社カネカ |
Fab型抗体の分泌量を増大できるFd鎖遺伝子又はL鎖遺伝子
|
|
PL3546572T3
(pl)
|
2013-05-13 |
2024-07-22 |
Cellectis |
Chimeryczny receptor antygenowy swoisty względem cd19 i jego zastosowania
|
|
WO2014202089A2
(en)
|
2013-06-18 |
2014-12-24 |
Roskilde Universitet |
Variants of anti-freeze polypeptides
|
|
US20160303174A1
(en)
|
2013-12-11 |
2016-10-20 |
The General Hospital Corporation |
Stem cell delivered oncolytic herpes simplex virus and methods for treating brain tumors
|
|
CA2934436A1
(en)
|
2013-12-20 |
2015-06-25 |
Cellectis |
Method of engineering multi-input signal sensitive t cell for immunotherapy
|
|
US9737592B1
(en)
|
2014-02-14 |
2017-08-22 |
David Gordon Bermudes |
Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment
|
|
ES2877606T3
(es)
|
2014-03-19 |
2021-11-17 |
Cellectis |
Método para la fabricación de células T CAR específicas de CD123 para inmunoterapia del cáncer
|
|
EP3137498A1
(en)
|
2014-05-02 |
2017-03-08 |
Cellectis |
Cs1 specific multi-chain chimeric antigen receptor
|
|
AU2015295349B2
(en)
|
2014-07-29 |
2020-09-24 |
Cellectis |
ROR1(NTRKR1)specific chimeric antigen receptors for cancer immunotherapy
|
|
WO2016016343A1
(en)
|
2014-07-31 |
2016-02-04 |
Cellectis |
Ror1 specific multi-chain chimeric antigen receptor
|
|
DK3189073T4
(da)
|
2014-09-04 |
2025-08-18 |
Cellectis |
Trofoblastglykoprotein (5t4, tpbg)-specifikke kimære antigenreceptorer til cancerimmunterapi
|
|
US9616114B1
(en)
|
2014-09-18 |
2017-04-11 |
David Gordon Bermudes |
Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
|
|
DK3250606T3
(da)
|
2015-01-26 |
2021-01-04 |
Cellectis |
ANTI-CLL1-specifikke enkeltkædede kimære antigenreceptorer (SCCARS) til cancerimmunterapi
|
|
ES2807591T3
(es)
|
2015-04-13 |
2021-02-23 |
Pfizer |
Receptores de antígeno quimérico dirigidos a antígeno de maduración de células B
|
|
EP3283529B1
(en)
|
2015-04-17 |
2023-06-07 |
The General Hospital Corporation |
Agents, systems and methods for treating cancer
|
|
US10676723B2
(en)
|
2015-05-11 |
2020-06-09 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
AU2016263513A1
(en)
|
2015-05-20 |
2017-11-23 |
Cellectis |
Anti-GD3 specific chimeric antigen receptors for cancer immunotherapy
|
|
KR102440820B1
(ko)
|
2015-09-08 |
2022-09-05 |
테리피온, 인크. |
ApoA-1 융합 폴리펩티드 및 관련 조성물 및 방법
|
|
US11352426B2
(en)
|
2015-09-21 |
2022-06-07 |
Aptevo Research And Development Llc |
CD3 binding polypeptides
|
|
MY192474A
(en)
|
2016-01-21 |
2022-08-23 |
Pfizer |
Chimeric antigen receptors targeting epidermal growth factor receptor variant iii
|
|
JP7213798B2
(ja)
|
2016-10-06 |
2023-01-27 |
エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド |
核酸アジュバントを送達するための細菌ミニ細胞およびその使用方法
|
|
WO2018073394A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Cell death inducing chimeric antigen receptors
|
|
US11180535B1
(en)
|
2016-12-07 |
2021-11-23 |
David Gordon Bermudes |
Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
|
|
US11129906B1
(en)
|
2016-12-07 |
2021-09-28 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
WO2018136163A2
(en)
|
2016-12-09 |
2018-07-26 |
Theripion, Inc. |
Tandem apoa-1 fusion polypeptides
|
|
BR112019020203A2
(pt)
|
2017-03-31 |
2020-06-02 |
Cellectis Sa |
Células imunes universais modificadas do receptor de anticorpos quiméricos anti-cd22
|
|
KR20190141206A
(ko)
|
2017-04-19 |
2019-12-23 |
알로젠 테라퓨틱스 인코포레이티드 |
개선된 t 세포 조성물 및 방법
|
|
WO2018222935A1
(en)
|
2017-06-02 |
2018-12-06 |
Pfizer Inc. |
Chimeric antigen receptors targeting flt3
|
|
US12144825B2
(en)
|
2017-06-30 |
2024-11-19 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
BR112020001180A2
(pt)
|
2017-07-20 |
2020-09-08 |
Aptevo Research And Development Llc |
proteínas de ligação a antígenos que se ligam a 5t4 e 4-1bb e composições e métodos relacionados
|
|
WO2019072824A1
(en)
|
2017-10-09 |
2019-04-18 |
Cellectis |
IMPROVED ANTI-CD123 CAR IN UNIVERSAL MODIFIED IMMUNE T LYMPHOCYTES
|
|
US11326156B2
(en)
|
2017-11-01 |
2022-05-10 |
Allogene Therapeutics, Inc. |
Modified caspase-9 polypeptides and methods of use thereof
|
|
JP7087107B2
(ja)
|
2017-12-20 |
2022-06-20 |
ハーバー・バイオメド・(シャンハイ)・カンパニー・リミテッド |
Ctla-4に結合する抗体およびその使用
|
|
US10150801B1
(en)
|
2017-12-27 |
2018-12-11 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
ES3039238T3
(en)
|
2017-12-27 |
2025-10-20 |
Imunami Laboratories Pte Ltd |
Recombinant polypeptides and methods of use thereof
|
|
PE20252242A1
(es)
|
2018-02-01 |
2025-09-15 |
Pfizer |
Receptores de antigeno quimericos dirigidos a cd70
|
|
WO2019152705A1
(en)
|
2018-02-01 |
2019-08-08 |
Pfizer Inc. |
Antibodies specific for cd70 and their uses
|
|
US12163169B2
(en)
|
2018-03-02 |
2024-12-10 |
Allogene Therapeutics, Inc. |
Inducible chimeric cytokine receptors
|
|
WO2020007593A1
(en)
|
2018-07-02 |
2020-01-09 |
Cellectis |
Chimeric antigen receptors (car)-expressing cells and combination treatment for immunotherapy of patients with relapse refractory adverse genetic risk aml
|
|
WO2020099572A1
(en)
|
2018-11-14 |
2020-05-22 |
Fundación Pública Andaluza Progreso Y Salud |
Polynucleotide for safer and more effective immunotherapies
|
|
US11471497B1
(en)
|
2019-03-13 |
2022-10-18 |
David Gordon Bermudes |
Copper chelation therapeutics
|
|
MX2022001882A
(es)
|
2019-08-12 |
2022-05-30 |
Aptevo Res & Development Llc |
Proteinas de union a 4-1bb y ox40 y composiciones y metodos relacionados anticuerpos contra 4-1bb, anticuerpos contra ox40.
|
|
US10675332B1
(en)
|
2019-08-26 |
2020-06-09 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
WO2021040610A1
(en)
|
2019-08-26 |
2021-03-04 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
US12285437B2
(en)
|
2019-10-30 |
2025-04-29 |
The Research Foundation For The State University Of New York |
Reversing the undesirable pH-profile of doxorubicin via activation of a disubstituted maleamic acid prodrug at tumor acidity
|
|
US20230167197A1
(en)
|
2020-03-18 |
2023-06-01 |
Memorial Sloan Kettering Cancer Center |
Anti-ceramide antibodies
|
|
WO2021185969A1
(en)
|
2020-03-18 |
2021-09-23 |
Numaferm Gmbh |
Variants of hlya and uses thereof
|
|
EP3882260A1
(en)
*
|
2020-03-18 |
2021-09-22 |
NUMAFERM GmbH |
Fragments of hlya and uses thereof
|
|
US10973908B1
(en)
|
2020-05-14 |
2021-04-13 |
David Gordon Bermudes |
Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
|
|
CN116568317A
(zh)
|
2020-06-22 |
2023-08-08 |
免疫实验室私人有限公司 |
用于癌症治疗的重组多肽和组合
|
|
AU2021312871A1
(en)
|
2020-07-21 |
2023-02-09 |
Allogene Therapeutics, Inc. |
Chimeric antigen receptors with enhanced signaling and activities and uses thereof
|
|
US12537071B1
(en)
|
2020-07-22 |
2026-01-27 |
David Gordon Bermudes |
Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
|
|
EP4215609A4
(en)
|
2020-09-21 |
2024-12-04 |
Fundación Pública Andaluza Progreso Y Salud |
POLYNUCLEOTIDE FOR PHYSIOLOGICAL EXPRESSION IN T CELLS
|
|
WO2022119976A1
(en)
|
2020-12-01 |
2022-06-09 |
Aptevo Research And Development Llc |
Heterodimeric psma and cd3-binding bispecific antibodies
|
|
MX2023007384A
(es)
|
2020-12-21 |
2023-07-05 |
Allogene Therapeutics Inc |
Car con puerta cd45 activado por proteasa.
|
|
MX2023008809A
(es)
|
2021-01-29 |
2023-08-04 |
Allogene Therapeutics Inc |
ATENUACIÓN O INACTIVACIÓN DE UNO O MÁS DE TAP2, NLRC5, ß2M, TRAC, RFX5, RFXAP Y RFXANK PARA MITIGAR EL RECONOCIMIENTO DE CÉLULAS T DE PRODUCTOS CELULARES ALOGÉNICOS.
|
|
EP4294916A2
(en)
|
2021-02-19 |
2023-12-27 |
Theripion, Inc. |
Dnase fusion polypeptides and related compositions and methods
|
|
EP4301772A1
(en)
|
2021-03-04 |
2024-01-10 |
Allogene Therapeutics, Inc. |
Fasl expression and fasr gene knockout to protect therapeutic cells from allogeneic rejection and activation-induced cell death
|
|
US20240228553A1
(en)
|
2021-03-18 |
2024-07-11 |
Numaferm Gmbh |
Fusion proteins comprising gg repeat sequences
|
|
BR112023026249A2
(pt)
|
2021-06-15 |
2024-03-05 |
Allogene Therapeutics Inc |
Direcionamento seletivo de células alorreativas cd70+ do hospedeiro para prolongar a persistência de células t car alogênicas
|
|
WO2023192895A1
(en)
|
2022-03-29 |
2023-10-05 |
Allogene Therapeutics Inc. |
Chimeric switch receptors for the conversion of immunesuppressive signals to costimulatory signals
|
|
CN119654406A
(zh)
|
2022-07-29 |
2025-03-18 |
艾洛基治疗公司 |
具有降低的基因表达以减轻免疫细胞识别的经工程化的细胞
|
|
EP4339202A1
(en)
|
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2024-03-20 |
NUMAFERM GmbH |
Fusion proteins comprising gg repeat sequences ii
|
|
KR20250133692A
(ko)
|
2023-01-06 |
2025-09-08 |
압테보 리서치 앤드 디벨롭먼트 엘엘씨 |
이중특이성 pd-l1 및 cd40 결합 분자 그리고 이의 용도
|
|
WO2024259220A1
(en)
|
2023-06-15 |
2024-12-19 |
Theripion, Inc. |
Pon3 and evolved pon1 fusion polypeptides
|
|
WO2025096560A1
(en)
|
2023-10-30 |
2025-05-08 |
Allogene Therapeutics, Inc. |
Engineered cells
|