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DK1137400T3 - Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode - Google Patents

Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode

Info

Publication number
DK1137400T3
DK1137400T3 DK99963398T DK99963398T DK1137400T3 DK 1137400 T3 DK1137400 T3 DK 1137400T3 DK 99963398 T DK99963398 T DK 99963398T DK 99963398 T DK99963398 T DK 99963398T DK 1137400 T3 DK1137400 T3 DK 1137400T3
Authority
DK
Denmark
Prior art keywords
peptide
preparation
compositions containing
extended release
subcutaneous implants
Prior art date
Application number
DK99963398T
Other languages
English (en)
Inventor
Alain Maquin
Patrice Mauriac
Pierre Marion
Original Assignee
Mediolanum Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Pharmaceuticals Ltd filed Critical Mediolanum Pharmaceuticals Ltd
Application granted granted Critical
Publication of DK1137400T3 publication Critical patent/DK1137400T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK99963398T 1998-12-10 1999-12-06 Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode DK1137400T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002655A IT1304152B1 (it) 1998-12-10 1998-12-10 Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato
PCT/EP1999/009536 WO2000033809A1 (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period

Publications (1)

Publication Number Publication Date
DK1137400T3 true DK1137400T3 (da) 2004-03-22

Family

ID=11381206

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99963398T DK1137400T3 (da) 1998-12-10 1999-12-06 Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode

Country Status (16)

Country Link
US (1) US6620422B1 (da)
EP (1) EP1137400B1 (da)
JP (1) JP4607329B2 (da)
KR (1) KR100676844B1 (da)
CN (1) CN1149975C (da)
AT (1) ATE253893T1 (da)
AU (1) AU757898C (da)
BR (1) BR9916053B1 (da)
CA (1) CA2354034C (da)
DE (1) DE69912836T2 (da)
DK (1) DK1137400T3 (da)
ES (1) ES2211211T3 (da)
IT (1) IT1304152B1 (da)
PT (1) PT1137400E (da)
TW (1) TW561053B (da)
WO (1) WO2000033809A1 (da)

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DK1532985T3 (da) 2002-06-25 2016-12-05 Takeda Pharmaceuticals Co Fremgangsmåde til fremstilling af en sammensætning med langvarig frigivelse
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
PT2246360E (pt) 2003-01-28 2012-08-31 Ironwood Pharmaceuticals Inc Composições para o tratamento de desordens gastrointestinais
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US20060003008A1 (en) * 2003-12-30 2006-01-05 Gibson John W Polymeric devices for controlled release of active agents
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
AU2005325213B2 (en) 2004-08-04 2010-10-07 Evonik Operations Gmbh Methods for manufacturing delivery devices and devices thereof
WO2006071208A1 (en) * 2004-12-23 2006-07-06 Durect Corporation Polymeric implants, preferably containing a mixture of peg and plg, for controlled release of a gnrh
PL1881823T3 (pl) 2005-05-17 2015-05-29 Sarcode Bioscience Inc Kompozycje i sposoby leczenia chorób oczu
ITMI20061538A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo
ITMI20061539A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo
ITMI20061545A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Particelle in grado di rilasciare il principio attivo per un periodo prolungato di tempo
CN101209238B (zh) * 2006-12-27 2012-05-09 辽宁省计划生育科学研究院 含孕二烯酮的生物降解型长效皮下避孕埋植剂及其制备
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US8067028B2 (en) * 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
CA2958665C (en) 2007-10-19 2021-03-02 Sarcode Bioscience Inc. Compositions and methods for treatment of diabetic retinopathy
CA2709712C (en) 2007-12-20 2016-05-10 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US20090258069A1 (en) * 2008-04-15 2009-10-15 John Burnier Delivery of LFA-1 antagonists to the gastrointestinal system
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
EP2246063A1 (en) * 2009-04-29 2010-11-03 Ipsen Pharma S.A.S. Sustained release formulations comprising GnRH analogues
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2011161531A1 (en) 2010-06-24 2011-12-29 Torrent Pharmaceuticals Limited Pharmaceutical composition containing goserelin for in-situ implant
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DE102011114864A1 (de) 2011-10-05 2013-04-11 Acino Ag Verfahren zur Herstellung einer homogenen Pulvermischung und Verfahren zur Herstellung eines Implantats sowie Implantat
EP3715345B8 (en) 2012-07-25 2024-05-29 Bausch + Lomb Ireland Limited Preparation of lfa-1 inhibitor
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
CN103446041B (zh) * 2013-08-27 2015-06-10 青岛东辉医药科技发展有限公司 一种亮丙瑞林缓控释药棒及其制备方法
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CN105267153B (zh) * 2015-11-27 2018-05-11 上海苏豪逸明制药有限公司 一种曲普瑞林缓释微粒及其制备方法
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CN105878174B (zh) * 2016-04-26 2021-06-29 广州帝奇医药技术有限公司 一种固体分散体及其制备方法与应用
CN107281493A (zh) * 2017-06-20 2017-10-24 苏州乔纳森新材料科技有限公司 一种聚乳酸‑聚乙醇酸共聚复合材料及其制备方法

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US5945128A (en) 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
BR9713702A (pt) * 1996-12-12 2000-10-31 Dds Drug Delivery Service Ges Preparado na forma de um composto coadjuvante de material matriz contendo opcionalmente substância ativa

Also Published As

Publication number Publication date
CN1149975C (zh) 2004-05-19
AU757898C (en) 2003-12-18
ITMI982655A1 (it) 2000-06-10
WO2000033809A1 (en) 2000-06-15
DE69912836T2 (de) 2004-11-11
TW561053B (en) 2003-11-11
BR9916053B1 (pt) 2011-04-19
CN1329485A (zh) 2002-01-02
AU757898B2 (en) 2003-03-13
DE69912836D1 (de) 2003-12-18
BR9916053A (pt) 2001-09-04
ATE253893T1 (de) 2003-11-15
KR20010082310A (ko) 2001-08-29
EP1137400B1 (en) 2003-11-12
PT1137400E (pt) 2004-03-31
CA2354034C (en) 2009-01-27
EP1137400A1 (en) 2001-10-04
JP4607329B2 (ja) 2011-01-05
IT1304152B1 (it) 2001-03-08
CA2354034A1 (en) 2000-06-15
JP2002531486A (ja) 2002-09-24
US6620422B1 (en) 2003-09-16
ES2211211T3 (es) 2004-07-01
AU1971100A (en) 2000-06-26
KR100676844B1 (ko) 2007-01-31

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