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DE69628484D1 - Zyklische Verbindungen, ihre Herstellung und ihre Verwendung als Tachykininrezeptorantagonisten - Google Patents

Zyklische Verbindungen, ihre Herstellung und ihre Verwendung als Tachykininrezeptorantagonisten

Info

Publication number
DE69628484D1
DE69628484D1 DE69628484T DE69628484T DE69628484D1 DE 69628484 D1 DE69628484 D1 DE 69628484D1 DE 69628484 T DE69628484 T DE 69628484T DE 69628484 T DE69628484 T DE 69628484T DE 69628484 D1 DE69628484 D1 DE 69628484D1
Authority
DE
Germany
Prior art keywords
preparation
receptor antagonists
cyclic compounds
tachykinin receptor
tachykinin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69628484T
Other languages
English (en)
Other versions
DE69628484T2 (de
Inventor
Hideaki Natsugari
Takenori Ishimaru
Takayuki Doi
Yoshinori Ikeura
Chiharu Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69628484D1 publication Critical patent/DE69628484D1/de
Application granted granted Critical
Publication of DE69628484T2 publication Critical patent/DE69628484T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69628484T 1995-03-24 1996-03-21 Zyklische Verbindungen, ihre Herstellung und ihre Verwendung als Tachykininrezeptorantagonisten Expired - Lifetime DE69628484T2 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP9143695 1995-03-24
JP9143695 1995-03-24
JP20755395 1995-07-20
JP20755395 1995-07-20
JP26472795 1995-09-18
JP26472795 1995-09-18
JP3003396 1996-01-23
JP3003396 1996-01-23

Publications (2)

Publication Number Publication Date
DE69628484D1 true DE69628484D1 (de) 2003-07-10
DE69628484T2 DE69628484T2 (de) 2004-05-19

Family

ID=27459171

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628484T Expired - Lifetime DE69628484T2 (de) 1995-03-24 1996-03-21 Zyklische Verbindungen, ihre Herstellung und ihre Verwendung als Tachykininrezeptorantagonisten

Country Status (17)

Country Link
US (3) US5786352A (de)
EP (1) EP0733632B1 (de)
KR (1) KR960034203A (de)
CN (1) CN1140172A (de)
AR (1) AR003937A1 (de)
AT (1) ATE242243T1 (de)
AU (1) AU699611B2 (de)
BR (1) BR9601125A (de)
CA (1) CA2172421A1 (de)
DE (1) DE69628484T2 (de)
ES (1) ES2194937T3 (de)
HU (1) HUP9600732A3 (de)
IL (1) IL117631A (de)
MX (1) MX9601072A (de)
NO (1) NO309272B1 (de)
NZ (1) NZ286256A (de)
TW (1) TW394773B (de)

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AU5305299A (en) * 1998-08-26 2000-03-21 Tanabe Seiyaku Co., Ltd. Naphthyridine derivatives and process for the preparation thereof
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US7030107B2 (en) * 2001-12-10 2006-04-18 Kyorin Pharmaceutical.Co., Ltd. Fused bicyclic pyridine derivatives as tachykinin receptor antagonists
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US20050113365A1 (en) * 2003-11-10 2005-05-26 Sir Isaac Newton Enterprises Llc Method and medicine for treating gastrointestinal disorder including irritable bowel syndrome
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US20060148782A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating a mammal presenting urinary incontinence, urinary urgency, or both
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Family Cites Families (10)

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ES431307A1 (es) * 1973-11-16 1976-09-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos derivados de quinoleina.
DE2357253A1 (de) * 1973-11-16 1975-05-22 Thomae Gmbh Dr K Neue chinolinderivate
DE2617101A1 (de) * 1976-04-17 1977-11-17 Thomae Gmbh Dr K Neue naphthyridine
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TW263498B (de) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
TW394773B (en) 2000-06-21
AU699611B2 (en) 1998-12-10
ATE242243T1 (de) 2003-06-15
NO961160D0 (no) 1996-03-21
BR9601125A (pt) 1998-01-06
CN1140172A (zh) 1997-01-15
EP0733632B1 (de) 2003-06-04
EP0733632A1 (de) 1996-09-25
NO961160L (no) 1996-09-25
HUP9600732A2 (en) 1997-03-28
US6147071A (en) 2000-11-14
KR960034203A (ko) 1996-10-22
NZ286256A (en) 1999-05-28
HU9600732D0 (en) 1996-05-28
IL117631A (en) 2000-11-21
HUP9600732A3 (en) 2000-03-28
DE69628484T2 (de) 2004-05-19
AU4826196A (en) 1996-10-03
AR003937A1 (es) 1998-09-30
MX9601072A (es) 1997-03-29
NO309272B1 (no) 2001-01-08
CA2172421A1 (en) 1996-09-25
US6489315B1 (en) 2002-12-03
IL117631A0 (en) 1996-07-23
ES2194937T3 (es) 2003-12-01
US5786352A (en) 1998-07-28

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