DE69532817T2 - Verwendung von pyrazole verbindungen zur behandlung von glomerulonephritis, krebs, atherosklerose oder restenose - Google Patents
Verwendung von pyrazole verbindungen zur behandlung von glomerulonephritis, krebs, atherosklerose oder restenose Download PDFInfo
- Publication number
- DE69532817T2 DE69532817T2 DE1995632817 DE69532817T DE69532817T2 DE 69532817 T2 DE69532817 T2 DE 69532817T2 DE 1995632817 DE1995632817 DE 1995632817 DE 69532817 T DE69532817 T DE 69532817T DE 69532817 T2 DE69532817 T2 DE 69532817T2
- Authority
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- Germany
- Prior art keywords
- lower alkyl
- use according
- hydrocarbyl
- membered heterocyclic
- heterocyclic aromatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33763094A | 1994-11-10 | 1994-11-10 | |
| US337630 | 1994-11-10 | ||
| PCT/US1995/014723 WO1996014843A2 (fr) | 1994-11-10 | 1995-11-09 | Compositions pharmaceutiques a base de pyrazole, agissant comme inhibiteurs des proteines kinases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69532817D1 DE69532817D1 (de) | 2004-05-06 |
| DE69532817T2 true DE69532817T2 (de) | 2005-01-13 |
Family
ID=23321325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE1995632817 Expired - Lifetime DE69532817T2 (de) | 1994-11-10 | 1995-11-09 | Verwendung von pyrazole verbindungen zur behandlung von glomerulonephritis, krebs, atherosklerose oder restenose |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5916908A (fr) |
| EP (1) | EP0788358B1 (fr) |
| JP (1) | JPH10509708A (fr) |
| KR (1) | KR970706813A (fr) |
| CN (1) | CN1165482A (fr) |
| AT (1) | ATE262902T1 (fr) |
| AU (1) | AU700964B2 (fr) |
| CA (1) | CA2203517A1 (fr) |
| DE (1) | DE69532817T2 (fr) |
| ES (1) | ES2219670T3 (fr) |
| MY (1) | MY113208A (fr) |
| TW (1) | TW474810B (fr) |
| WO (1) | WO1996014843A2 (fr) |
Families Citing this family (94)
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|---|---|---|---|---|
| GB9222253D0 (en) * | 1992-10-23 | 1992-12-09 | Celltech Ltd | Chemical compounds |
| GB9304920D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| GB9304919D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| DE69433594T2 (de) * | 1993-12-22 | 2004-08-05 | Celltech R&D Ltd., Slough | Trisubstituierte phenyl-derivate, verfahren zu deren herstellung und deren verwendung als phosphodiesterase (typ iv) hemmstoffe |
| GB9326699D0 (en) * | 1993-12-22 | 1994-03-02 | Celltech Ltd | Chemical compounds |
| US6245774B1 (en) | 1994-06-21 | 2001-06-12 | Celltech Therapeutics Limited | Tri-substituted phenyl or pyridine derivatives |
| GB9523675D0 (en) * | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9526245D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9526246D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9608435D0 (en) * | 1996-04-24 | 1996-06-26 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9619284D0 (en) * | 1996-09-16 | 1996-10-30 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9622363D0 (en) * | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds |
| WO1998024768A1 (fr) * | 1996-12-03 | 1998-06-11 | Banyu Pharmaceutical Co., Ltd. | Nouveaux derives d'uree |
| GB9625184D0 (en) * | 1996-12-04 | 1997-01-22 | Celltech Therapeutics Ltd | Chemical compounds |
| AU5410498A (en) * | 1996-12-12 | 1998-07-03 | Banyu Pharmaceutical Co., Ltd. | Pyrazole derivatives |
| CA2274593A1 (fr) * | 1996-12-13 | 1998-06-18 | Banyu Pharmaceutical Co., Ltd. | Derives d'aminopyrazole |
| US6180653B1 (en) | 1996-12-16 | 2001-01-30 | Banyu Pharmaceutical Co., Ltd. | Aminopyrazole derivatives |
| US6057329A (en) * | 1996-12-23 | 2000-05-02 | Celltech Therapeutics Limited | Fused polycyclic 2-aminopyrimidine derivatives |
| GB9705361D0 (en) * | 1997-03-14 | 1997-04-30 | Celltech Therapeutics Ltd | Chemical compounds |
| ATE249217T1 (de) | 1997-10-06 | 2003-09-15 | Abbott Gmbh & Co Kg | Indeno(1,2-c)-,naphtho(1,2-c)-und benzo(6, 7)cyclohepta(1,2-c)pyrazolderivate |
| WO1999017770A1 (fr) | 1997-10-06 | 1999-04-15 | Basf Aktiengesellschaft | Derives d'indeno[1,2-c]pyrazole utiles pour inhiber l'activite de tyrosine kinase |
| US6376527B1 (en) | 1998-05-05 | 2002-04-23 | Syntex (U.S.A.) Llc | Pyrazole derivatives-p38 map kinase inhibitors |
| US6316466B1 (en) | 1998-05-05 | 2001-11-13 | Syntex (U.S.A.) Llc | Pyrazole derivatives P-38 MAP kinase inhibitors |
| HN2000000051A (es) * | 1999-05-19 | 2001-02-02 | Pfizer Prod Inc | Derivados heterociclicos utiles como agentes anticancerosos |
| UA71971C2 (en) | 1999-06-04 | 2005-01-17 | Agoron Pharmaceuticals Inc | Diaminothiazoles, composition based thereon, a method for modulation of protein kinases activity, a method for the treatment of diseases mediated by protein kinases |
| TWI262914B (en) | 1999-07-02 | 2006-10-01 | Agouron Pharma | Compounds and pharmaceutical compositions for inhibiting protein kinases |
| US7141581B2 (en) | 1999-07-02 | 2006-11-28 | Agouron Pharmaceuticals, Inc. | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use |
| PE20010306A1 (es) * | 1999-07-02 | 2001-03-29 | Agouron Pharma | Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa |
| US6387900B1 (en) | 1999-08-12 | 2002-05-14 | Pharmacia & Upjohn S.P.A. | 3(5)-ureido-pyrazole derivatives process for their preparation and their use as antitumor agents |
| AP2002002442A0 (en) | 1999-08-12 | 2002-03-31 | Pharmacia Italia Spa | 3(5)-Amino-pyrazole derivatives, process for their preparation and their preparation and their use as antitumor agents. |
| YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
| HN2001000008A (es) | 2000-01-21 | 2003-12-11 | Inc Agouron Pharmaceuticals | Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo |
| DE60106409T2 (de) * | 2000-02-07 | 2006-02-02 | Bristol-Myers Squibb Co. | 3-aminopyrazole als inhibitoren von cyclinabhängigen kinasen |
| WO2001079198A1 (fr) * | 2000-04-18 | 2001-10-25 | Agouron Pharmaceuticals, Inc. | Pyrazoles permettant d'inhiber des proteines kinases |
| MXPA03001189A (es) | 2000-08-09 | 2004-05-14 | Agouron Pharma | Compuestos de pirazol-tiazol, composiciones farmaceuticas que los contienen y su uso para inhibir las cinasas dependientes de ciclinas. |
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| US6660731B2 (en) * | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US7473691B2 (en) * | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| CA2432303C (fr) | 2000-12-21 | 2010-04-13 | Vertex Pharmaceuticals Incorporated | Composes de pyrazole utilises comme inhibiteurs de la proteine kinase |
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| HN2002000156A (es) | 2001-07-06 | 2003-11-27 | Inc Agouron Pharmaceuticals | Derivados de benzamida tiazol y composiciones farmaceuticas para inhibir la proliferacion de celulas y metodos para su utilización. |
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| MY141867A (en) * | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| PT1532145E (pt) | 2002-08-02 | 2007-01-31 | Vertex Pharma | Composiçoes de pirazole úteis como inibidores de gsk-3 |
| AR042067A1 (es) * | 2002-11-27 | 2005-06-08 | Bayer Pharmaceuticals Corp | Derivados de anilinopirazol utiles en el tratamiento de la diabetes |
| BR0317548A (pt) | 2002-12-19 | 2005-11-22 | Pfizer | Compostos de indazole e composições farmacêuticas para a inibição de proteìnas-cinases e métodos para o seu uso |
| US7601718B2 (en) * | 2003-02-06 | 2009-10-13 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| EP1620088A4 (fr) * | 2003-04-28 | 2007-08-29 | Bayer Pharmaceuticals Corp | Derives d'acide indole acetique et leur utilisation en tant qu'agents pharmaceutiques |
| US20070161633A1 (en) * | 2003-05-02 | 2007-07-12 | Elan Pharmaceuticals, Inc. | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (1-aminocarbonyl)eth-1-yl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases |
| ATE410161T1 (de) | 2003-05-02 | 2008-10-15 | Elan Pharm Inc | 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazol-3- carbonsäureamid-derivate und verwandte verbindungen als bradykinin b1 rezeptor antagonisten zur behandlung von entzündlichen erkrankungen |
| US20050032868A1 (en) * | 2003-05-02 | 2005-02-10 | Garofalo Albert W. | Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists |
| EP1651612B9 (fr) | 2003-07-22 | 2012-09-05 | Astex Therapeutics Limited | Composes 1h-pyrazole 3,4-disubstitues et leur utilisation en tant que kinases dependant des cyclines (cdk) et modulateurs de la glycogene synthase kinase-3 (gsk-3) |
| BRPI0412820A (pt) * | 2003-07-25 | 2006-09-26 | Pfizer | compostos de aminopirazol e utilização como inibidores de chk1 |
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| EP1812424A4 (fr) * | 2004-11-17 | 2009-07-08 | Miikana Therapeutics Inc | Inhibiteurs de kinase |
| US8404718B2 (en) | 2005-01-21 | 2013-03-26 | Astex Therapeutics Limited | Combinations of pyrazole kinase inhibitors |
| AR054425A1 (es) | 2005-01-21 | 2007-06-27 | Astex Therapeutics Ltd | Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico. |
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| JP2009504771A (ja) * | 2005-08-18 | 2009-02-05 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラジンキナーゼ阻害剤 |
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| MX2008005717A (es) * | 2005-11-03 | 2008-10-15 | Vertex Pharma | Aminopirimidinas utiles como inhibidores de la cinasa. |
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| KR101450356B1 (ko) * | 2006-11-24 | 2014-10-15 | 에이씨 이뮨 에스.에이. | 알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 n-(메틸)-1h-피라졸-3-아민, n-(메틸)-피리딘-2-아민 및 n-(메틸)-티아졸-2-아민 유도체 |
| ES2347721T3 (es) * | 2006-12-19 | 2010-11-03 | Vertex Pharmaceuticals, Inc. | Aminopirimidinas utiles como inhibidores de proteina quinasas. |
| US7737149B2 (en) | 2006-12-21 | 2010-06-15 | Astrazeneca Ab | N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof |
| WO2008112642A1 (fr) * | 2007-03-09 | 2008-09-18 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines utiles en tant qu'inhibiteurs des protéines kinases |
| CA2679701A1 (fr) * | 2007-03-09 | 2008-09-18 | Vertex Pharmaceuticals Incorporated | Utilisation des aminopyridines comme inhibiteurs de proteines kinases |
| RU2009137390A (ru) * | 2007-03-09 | 2011-04-20 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | Аминопиримидины, пригодные в качестве ингибиторов протеинкиназ |
| CA2683785A1 (fr) | 2007-04-13 | 2008-10-23 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines utilisees en tant qu'inhibiteurs de kinases |
| JP5389785B2 (ja) * | 2007-05-02 | 2014-01-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤として有用なチアゾールおよびピラゾール |
| AU2008247595A1 (en) * | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
| CA2694381A1 (fr) * | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines servant d'inhibiteurs de kinases |
| CA2687966A1 (fr) * | 2007-05-24 | 2008-12-04 | Vertex Pharmaceuticals Incorporated | Thiazoles et pyrazoles utiles en tant qu'inhibiteurs de kinase |
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| JP6165733B2 (ja) | 2011-09-16 | 2017-07-19 | ノバルティス アーゲー | N−置換ヘテロシクリルカルボキサミド類 |
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| ES2853483T3 (es) | 2013-03-15 | 2021-09-16 | Verseon Int Corporation | Compuestos aromáticos multisustituidos como inhibidores de la serina proteasa |
| CN103232394B (zh) * | 2013-05-14 | 2014-09-24 | 浙江医药高等专科学校 | 含吡唑类化合物、其制备方法和用途 |
| US10189810B2 (en) | 2014-09-17 | 2019-01-29 | Verseon Corporation | Pyrazolyl-substituted pyridone compounds as serine protease inhibitors |
| CA2977993A1 (fr) | 2015-02-27 | 2016-09-01 | Verseon Corporation | Composes pyrazole substitues a utiliser en tant qu'inhibiteurs de serine protease |
| CN112694474B (zh) * | 2019-10-23 | 2022-03-18 | 四川大学 | 吲唑类衍生物及其制备方法和用途 |
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|---|---|---|---|---|
| JPS49100080A (fr) * | 1973-02-01 | 1974-09-20 | ||
| US4622330A (en) * | 1982-12-20 | 1986-11-11 | Merck & Co., Inc. | Antiprotozoal 3-amino or substituted amino pyrazoles |
| JPH01258695A (ja) * | 1988-04-07 | 1989-10-16 | Yamanouchi Pharmaceut Co Ltd | (ピラゾリルアミノ)メチレンビス(ホスホン酸)誘導体及びその医薬 |
| US5196446A (en) * | 1990-04-16 | 1993-03-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Certain indole compounds which inhibit EGF receptor tyrosine kinase |
| SG64322A1 (en) * | 1991-05-10 | 1999-04-27 | Rhone Poulenc Rorer Int | Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase |
| EP0541486A1 (fr) * | 1991-11-07 | 1993-05-12 | Ciba-Geigy Ag | Conjugates polycycliques |
| WO1994013643A1 (fr) * | 1992-12-17 | 1994-06-23 | Pfizer Inc. | Pyrazoles et pyrazolopyrimidines presentant une activite d'antagonistes du facteur de liberation de la cortitrophine |
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| PH30300A (en) * | 1993-05-07 | 1997-01-20 | Ciba Geigy Ag | Polycyclic compounds and processes for the preparation thereof |
| US5605820A (en) * | 1994-06-23 | 1997-02-25 | Chemgenics Pharmaceuticals, Inc. | Production of strains having biological activities by sexual crosses between vegetatively incompatible strains of Aspergillus nidulans |
-
1995
- 1995-11-09 AT AT95939917T patent/ATE262902T1/de not_active IP Right Cessation
- 1995-11-09 DE DE1995632817 patent/DE69532817T2/de not_active Expired - Lifetime
- 1995-11-09 WO PCT/US1995/014723 patent/WO1996014843A2/fr not_active Ceased
- 1995-11-09 CA CA002203517A patent/CA2203517A1/fr not_active Abandoned
- 1995-11-09 EP EP95939917A patent/EP0788358B1/fr not_active Expired - Lifetime
- 1995-11-09 US US08/556,178 patent/US5916908A/en not_active Expired - Lifetime
- 1995-11-09 AU AU41561/96A patent/AU700964B2/en not_active Ceased
- 1995-11-09 ES ES95939917T patent/ES2219670T3/es not_active Expired - Lifetime
- 1995-11-09 CN CN95196127A patent/CN1165482A/zh active Pending
- 1995-11-09 KR KR1019970703199A patent/KR970706813A/ko not_active Ceased
- 1995-11-09 JP JP8516253A patent/JPH10509708A/ja not_active Ceased
- 1995-11-10 MY MYPI95003420A patent/MY113208A/en unknown
- 1995-11-10 TW TW084111931A patent/TW474810B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1165482A (zh) | 1997-11-19 |
| JPH10509708A (ja) | 1998-09-22 |
| KR970706813A (ko) | 1997-12-01 |
| ES2219670T3 (es) | 2004-12-01 |
| MX9703488A (es) | 1998-07-31 |
| AU4156196A (en) | 1996-06-06 |
| EP0788358B1 (fr) | 2004-03-31 |
| CA2203517A1 (fr) | 1996-05-23 |
| DE69532817D1 (de) | 2004-05-06 |
| WO1996014843A2 (fr) | 1996-05-23 |
| TW474810B (en) | 2002-02-01 |
| US5916908A (en) | 1999-06-29 |
| WO1996014843A3 (fr) | 1996-05-23 |
| ATE262902T1 (de) | 2004-04-15 |
| MY113208A (en) | 2001-12-31 |
| AU700964B2 (en) | 1999-01-14 |
| EP0788358A2 (fr) | 1997-08-13 |
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