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DE60329615D1 - Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivats - Google Patents

Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivats

Info

Publication number
DE60329615D1
DE60329615D1 DE60329615T DE60329615T DE60329615D1 DE 60329615 D1 DE60329615 D1 DE 60329615D1 DE 60329615 T DE60329615 T DE 60329615T DE 60329615 T DE60329615 T DE 60329615T DE 60329615 D1 DE60329615 D1 DE 60329615D1
Authority
DE
Germany
Prior art keywords
derivative
formula
pyridyl
give
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60329615T
Other languages
English (en)
Inventor
Kenichi Koyakumaru
Yoshimi Fukunaga
Youichi Satake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Eisai R&D Management Co Ltd
Original Assignee
Kuraray Co Ltd
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd, Eisai R&D Management Co Ltd filed Critical Kuraray Co Ltd
Application granted granted Critical
Publication of DE60329615D1 publication Critical patent/DE60329615D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60329615T 2002-07-23 2003-07-23 Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivats Expired - Lifetime DE60329615D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002214098A JP4208512B2 (ja) 2002-07-23 2002-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法
PCT/JP2003/009316 WO2004009553A1 (ja) 2002-07-23 2003-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法

Publications (1)

Publication Number Publication Date
DE60329615D1 true DE60329615D1 (de) 2009-11-19

Family

ID=30767870

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60329615T Expired - Lifetime DE60329615D1 (de) 2002-07-23 2003-07-23 Verfahren zur herstellung eines 5-(2'-pyridyl)-2-pyridonderivats

Country Status (13)

Country Link
US (1) US7524967B2 (de)
EP (1) EP1553086B1 (de)
JP (1) JP4208512B2 (de)
KR (1) KR101025528B1 (de)
CN (1) CN100393702C (de)
AT (1) ATE444952T1 (de)
AU (1) AU2003252241B2 (de)
CA (1) CA2493036C (de)
DE (1) DE60329615D1 (de)
HK (1) HK1077578B (de)
IL (1) IL166451A (de)
MX (1) MXPA05000944A (de)
WO (1) WO2004009553A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
KR20080007233A (ko) * 2005-04-04 2008-01-17 에자이 가부시키가이샤 두통용 디히드로피리딘 화합물 및 조성물
CA2620352A1 (en) 2005-08-29 2007-03-08 Vertex Pharmaceuticals Incorporated 3, 5-disubstituted pyrid-2-ones useful as inhibitors of tec family of non-receptor tyrosine kinases
DE602006020293D1 (de) 2005-08-29 2011-04-07 Vertex Pharma 3,5-disubstituierte pyrid-2-one, die als hemmer der tec-familie von nicht-rezeptor tyrosin-kinasen nützlich sind
EP1919891B1 (de) * 2005-08-29 2012-03-07 Vertex Pharmaceuticals Incorporated 3,5-disubstituierte pyrid-2-one, die sich als inhibitoren der tec-familie von nicht-rezeptor-tyrosinkinasen eignen
JP4865337B2 (ja) * 2006-01-24 2012-02-01 富士フイルムファインケミカルズ株式会社 2,3’−ビピリジル−6’−オンの製造方法
WO2008093392A1 (ja) * 2007-01-29 2008-08-07 Fujifilm Finechemicals Co., Ltd. 2,3'-ビピリジル-6'-オンの製造方法
US20100099714A1 (en) * 2007-03-05 2010-04-22 Eisai R&D Management Co., Ltd. AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases
JP2010524844A (ja) * 2007-04-26 2010-07-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 認知症のためのシンナミド化合物
WO2009081872A1 (ja) * 2007-12-21 2009-07-02 Kuraray Co., Ltd. 6-ハロゲノ-3-アリールピリジン誘導体の製造方法
ITMI20111952A1 (it) * 2011-10-27 2013-04-28 Italiana Sint Spa Procedimento per la prepazione di 2-metossi-5-(piridin-2-il)piridina, un intermedio del perampanel
US9096574B2 (en) 2012-01-03 2015-08-04 Mapi Pharma Ltd. Polymorphs of perampanel
US9695147B2 (en) 2013-07-25 2017-07-04 Teva Pharmaceuticals International Gmbh Process for the preparation of perampanel
CN104725301A (zh) * 2013-12-20 2015-06-24 北京蓝贝望生物医药科技股份有限公司 一种1,2-二氢吡啶-2-酮衍生物的制备方法
EP3259262A4 (de) 2015-02-17 2018-08-01 Mapi Pharma Limited Verfahren und zwischenprodukte zur herstellung von perampanel
WO2020033354A2 (en) 2018-08-06 2020-02-13 Olive Seed Industries, Llc Methods and systems for personalizing visitor experience at a venue
CN116930351A (zh) * 2023-06-08 2023-10-24 上海现代制药股份有限公司 一种hplc测定吡仑帕奈关键起始物料有关物质的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
DE19633746A1 (de) 1996-08-22 1998-02-26 Basf Ag Substituierte 2-Phenylpyridine
DE19636995A1 (de) * 1996-09-12 1998-03-19 Basf Ag Verfahren zur Herstellung substituierter Phenylpyridine
JP4176201B2 (ja) 1998-09-02 2008-11-05 株式会社クラレ 5−ハロゲノ−2−置換ピリジンの製造方法
NZ517324A (en) * 1999-10-11 2003-09-26 Pfizer 5-(2-substituted-5-heterocyclylsulphonylpyrid-3-YL)- dihydropyrazolo[4,3-d]pyrimidin-7-ones as phosphodiesterase inhibitors
US20020045613A1 (en) 2000-04-27 2002-04-18 Heinz Pauls 1-aroyl-piperidinyl benzamidines
CN1245386C (zh) * 2000-06-12 2006-03-15 卫材株式会社 1,2-二氢吡啶化合物及其制备方法和用途

Also Published As

Publication number Publication date
WO2004009553A1 (ja) 2004-01-29
AU2003252241B2 (en) 2008-12-04
CA2493036C (en) 2011-03-22
IL166451A0 (en) 2006-01-15
KR20050019919A (ko) 2005-03-03
AU2003252241A1 (en) 2004-02-09
US20060004205A1 (en) 2006-01-05
IL166451A (en) 2011-07-31
US7524967B2 (en) 2009-04-28
EP1553086A1 (de) 2005-07-13
CA2493036A1 (en) 2004-01-29
HK1077578B (zh) 2009-03-27
HK1077578A1 (en) 2006-02-17
CN1671665A (zh) 2005-09-21
EP1553086B1 (de) 2009-10-07
EP1553086A4 (de) 2007-04-25
JP2004051592A (ja) 2004-02-19
ATE444952T1 (de) 2009-10-15
CN100393702C (zh) 2008-06-11
KR101025528B1 (ko) 2011-04-04
MXPA05000944A (es) 2005-10-18
JP4208512B2 (ja) 2009-01-14

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Legal Events

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