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WO2008093392A1 - 2,3'-ビピリジル-6'-オンの製造方法 - Google Patents

2,3'-ビピリジル-6'-オンの製造方法 Download PDF

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Publication number
WO2008093392A1
WO2008093392A1 PCT/JP2007/051414 JP2007051414W WO2008093392A1 WO 2008093392 A1 WO2008093392 A1 WO 2008093392A1 JP 2007051414 W JP2007051414 W JP 2007051414W WO 2008093392 A1 WO2008093392 A1 WO 2008093392A1
Authority
WO
WIPO (PCT)
Prior art keywords
bipyridyl
production
derivative
bipyridine derivative
bipyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2007/051414
Other languages
English (en)
French (fr)
Inventor
Takayuki Sonoda
Taichi Shintou
Kenichi Onoue
Takashi Nagayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Finechemicals Co Ltd
Eisai R&D Management Co Ltd
Original Assignee
Fujifilm Finechemicals Co Ltd
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Finechemicals Co Ltd, Eisai R&D Management Co Ltd filed Critical Fujifilm Finechemicals Co Ltd
Priority to EP07707645.3A priority Critical patent/EP2123639B1/en
Priority to US12/524,822 priority patent/US20100016603A1/en
Priority to PCT/JP2007/051414 priority patent/WO2008093392A1/ja
Publication of WO2008093392A1 publication Critical patent/WO2008093392A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/10Process efficiency

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

 2,3’-ビピリジル-6’-オンの製造を高価な触媒や特殊な設備を用いることなく、高純度且つ低コストで工業的な規模において生産可能な製造方法。アセチルピリジン誘導体と、一般式(II)~(V)で表される化合物の少なくとも1つを反応させてビピリジン誘導体を合成し、次いで一貫法で加水分解する工程を含むことを特徴とする2,3'-ビピリジル-6'-オンの製造方法。式(II)~(V)中、R2~R8、X、Yは所定の基を表す。
PCT/JP2007/051414 2007-01-29 2007-01-29 2,3'-ビピリジル-6'-オンの製造方法 Ceased WO2008093392A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07707645.3A EP2123639B1 (en) 2007-01-29 2007-01-29 Process for production of 2,3'-bipyridyl-6'-one
US12/524,822 US20100016603A1 (en) 2007-01-29 2007-01-29 Production process of 2,3'-bipyridyl-6'-one
PCT/JP2007/051414 WO2008093392A1 (ja) 2007-01-29 2007-01-29 2,3'-ビピリジル-6'-オンの製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/051414 WO2008093392A1 (ja) 2007-01-29 2007-01-29 2,3'-ビピリジル-6'-オンの製造方法

Publications (1)

Publication Number Publication Date
WO2008093392A1 true WO2008093392A1 (ja) 2008-08-07

Family

ID=39673712

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/051414 Ceased WO2008093392A1 (ja) 2007-01-29 2007-01-29 2,3'-ビピリジル-6'-オンの製造方法

Country Status (3)

Country Link
US (1) US20100016603A1 (ja)
EP (1) EP2123639B1 (ja)
WO (1) WO2008093392A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2586777A1 (en) 2011-10-27 2013-05-01 F.I.S. Fabbrica Italiana Sintetici S.p.A. Process for the preparation of 2-alkoxy-5-(pyridin-2-yl)pyridine, an intermediate of perampanel

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012173694A1 (en) 2011-06-17 2012-12-20 Fluidic, Inc. Ionic liquid containing sulfonate ions
EA031384B1 (ru) 2013-07-25 2018-12-28 Тева Фармасьютикалз Интернэшнл Гмбх Улучшенные способы получения перампанеля
CN104356056B (zh) * 2014-11-19 2017-04-05 南京华威医药科技开发有限公司 吡仑帕奈中间体的制备方法
JP6916161B2 (ja) * 2018-02-20 2021-08-11 インディアン オイル コーポレーション リミテッド ポリオレフィンポリマー用添加剤および熱可塑性組成物
US11424484B2 (en) 2019-01-24 2022-08-23 Octet Scientific, Inc. Zinc battery electrolyte additive

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6431768A (en) * 1987-07-11 1989-02-02 Bayer Ag 5-halogeno-6-amino-nicotinic acid halides, manufacture and use
JPH01319461A (ja) * 1988-05-07 1989-12-25 Bayer Ag 2,3‐ジクロル‐5‐アセチルピリジンの製造法
JP2001261646A (ja) 2000-03-17 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の製造法
JP2001261653A (ja) 2000-03-17 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の合成法
JP2001261647A (ja) * 2000-03-22 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の製造方法
JP2003160550A (ja) 2001-11-29 2003-06-03 Sankio Chemical Co Ltd 新規な(3−ジメチルアミノ−2−プロペニリデン)ジメチルアンモニウム誘導体・bf4塩
WO2004009553A1 (ja) * 2002-07-23 2004-01-29 Kuraray Co., Ltd. 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法
JP2005213239A (ja) 2004-02-02 2005-08-11 Sankio Chemical Co Ltd ピリジン誘導体の製造方法
JP2005239672A (ja) * 2004-02-27 2005-09-08 Sankio Chemical Co Ltd ピリジン誘導体の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60144361D1 (de) * 2000-08-25 2011-05-19 Kaneka Corp Verfahren zur Reinigung von Vinylpolymeren
US6348637B1 (en) * 2000-09-26 2002-02-19 Uop Llc Multifunction fractionation column for adsorptive separation processes
GB0129260D0 (en) * 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6431768A (en) * 1987-07-11 1989-02-02 Bayer Ag 5-halogeno-6-amino-nicotinic acid halides, manufacture and use
JPH01319461A (ja) * 1988-05-07 1989-12-25 Bayer Ag 2,3‐ジクロル‐5‐アセチルピリジンの製造法
JP2001261646A (ja) 2000-03-17 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の製造法
JP2001261653A (ja) 2000-03-17 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の合成法
JP2001261647A (ja) * 2000-03-22 2001-09-26 Sankio Chemical Co Ltd ピリジン誘導体の製造方法
JP2003160550A (ja) 2001-11-29 2003-06-03 Sankio Chemical Co Ltd 新規な(3−ジメチルアミノ−2−プロペニリデン)ジメチルアンモニウム誘導体・bf4塩
WO2004009553A1 (ja) * 2002-07-23 2004-01-29 Kuraray Co., Ltd. 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法
JP2005213239A (ja) 2004-02-02 2005-08-11 Sankio Chemical Co Ltd ピリジン誘導体の製造方法
JP2005239672A (ja) * 2004-02-27 2005-09-08 Sankio Chemical Co Ltd ピリジン誘導体の製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2123639A4

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2586777A1 (en) 2011-10-27 2013-05-01 F.I.S. Fabbrica Italiana Sintetici S.p.A. Process for the preparation of 2-alkoxy-5-(pyridin-2-yl)pyridine, an intermediate of perampanel

Also Published As

Publication number Publication date
EP2123639A4 (en) 2011-07-13
US20100016603A1 (en) 2010-01-21
EP2123639A1 (en) 2009-11-25
EP2123639B1 (en) 2014-03-26

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