MXPA05008179A - Procedimiento para la fabricacion de alcaloides de quinazolina. - Google Patents
Procedimiento para la fabricacion de alcaloides de quinazolina.Info
- Publication number
- MXPA05008179A MXPA05008179A MXPA05008179A MXPA05008179A MXPA05008179A MX PA05008179 A MXPA05008179 A MX PA05008179A MX PA05008179 A MXPA05008179 A MX PA05008179A MX PA05008179 A MXPA05008179 A MX PA05008179A MX PA05008179 A MXPA05008179 A MX PA05008179A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- methods
- producing
- quinazoline alkaloids
- iii
- Prior art date
Links
- 229930002339 quinazoline alkaloid Natural products 0.000 title 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 238000004519 manufacturing process Methods 0.000 abstract 3
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000006722 reduction reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Addiction (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La invencion se refiere a un metodo para la fabricacion de un compuesto de formula (I) haciendo reaccionar un compuesto de formula (II) con 2-pirrolidona, por lo cual se utiliza un excedente de la 2-pirrolidona, con relacion al compuesto (II). la invencion tambien se refiere a un metodo para la fabricacion de un compuesto de formula (III), que comprende las siguientes etapas: (A) fabricacion del compuesto (I); (B) reaccion de reduccion para obtener el compuesto (III) en forma de sal; (C) liberacion del compuesto (III) a partir de la sal (ver formulas (I), (II) y (III)).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10304141A DE10304141B4 (de) | 2003-02-03 | 2003-02-03 | Verfahren zur Herstellung von Chinazolin-Alkaloiden |
| PCT/EP2004/000485 WO2004069836A1 (de) | 2003-02-03 | 2004-01-22 | Verfahren zur herstellung von chinazolin-alkaloiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05008179A true MXPA05008179A (es) | 2006-02-17 |
Family
ID=32747532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05008179A MXPA05008179A (es) | 2003-02-03 | 2004-01-22 | Procedimiento para la fabricacion de alcaloides de quinazolina. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7495096B2 (es) |
| EP (1) | EP1590351B1 (es) |
| JP (1) | JP2006516578A (es) |
| KR (1) | KR20050096165A (es) |
| CN (1) | CN100558727C (es) |
| AR (1) | AR042946A1 (es) |
| AT (1) | ATE407135T1 (es) |
| AU (1) | AU2004208873B2 (es) |
| BR (1) | BRPI0407012A (es) |
| CA (1) | CA2514945A1 (es) |
| DE (2) | DE10304141B4 (es) |
| DK (1) | DK1590351T3 (es) |
| EA (1) | EA009047B1 (es) |
| ES (1) | ES2314366T3 (es) |
| MX (1) | MXPA05008179A (es) |
| MY (1) | MY141734A (es) |
| NO (1) | NO20053689L (es) |
| NZ (1) | NZ541101A (es) |
| PL (1) | PL378406A1 (es) |
| PT (1) | PT1590351E (es) |
| SI (1) | SI1590351T1 (es) |
| TW (1) | TW200418811A (es) |
| UA (1) | UA81287C2 (es) |
| WO (1) | WO2004069836A1 (es) |
| ZA (1) | ZA200505160B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004048927A1 (de) * | 2004-10-06 | 2006-04-20 | Lts Lohmann Therapie-Systeme Ag | Pharmazeutische Kombination enthaltend Desoxypeganin und Cyp2D6 Inhibitoren |
| JP7498108B2 (ja) | 2017-08-03 | 2024-06-11 | ガレクティン・サイエンシーズ・リミテッド・ライアビリティ・カンパニー | 医学的障害の予防および治療のための化合物およびその使用 |
| KR102728780B1 (ko) * | 2021-11-30 | 2024-11-08 | 이화여자대학교 산학협력단 | 데옥시바시시논을 유효성분으로 포함하는 미백용 조성물 및 상기 데옥시바시시논 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU605614A1 (ru) * | 1971-10-20 | 1978-05-05 | Ордена Трудового Красного Знамени Институт Химии Растительных Веществ Ан Узбекской Сср | Антихолинэстеразное средство |
| JP3180464B2 (ja) * | 1991-08-30 | 2001-06-25 | 新日本理化株式会社 | ジアセタール化合物の製造方法 |
| DE19530606A1 (de) * | 1995-08-21 | 1997-02-27 | Basf Ag | 1-(Pyridyl)-pyrazole |
| JP3958452B2 (ja) * | 1997-10-31 | 2007-08-15 | 大日精化工業株式会社 | 新規化学発光試薬及びその製造方法 |
| DE19906975B4 (de) | 1999-02-19 | 2004-04-15 | Lts Lohmann Therapie-Systeme Ag | Arzneiform zur Behandlung von Alzheimer'scher Demenz |
| DE19906978B4 (de) * | 1999-02-19 | 2004-07-08 | Lts Lohmann Therapie-Systeme Ag | Pharmazeutische Zusammensetzung enthaltend Desoxypeganin zur Behandlung der Drogenabhängigkeit |
| DE19906979B4 (de) | 1999-02-19 | 2004-07-08 | Lts Lohmann Therapie-Systeme Ag | Verwendung von Desoxypeganin zur Behandlung der Nikotinabhängigkeit |
-
2003
- 2003-02-03 DE DE10304141A patent/DE10304141B4/de not_active Expired - Fee Related
-
2004
- 2004-01-22 ES ES04704202T patent/ES2314366T3/es not_active Expired - Lifetime
- 2004-01-22 EA EA200501135A patent/EA009047B1/ru not_active IP Right Cessation
- 2004-01-22 NZ NZ541101A patent/NZ541101A/en not_active IP Right Cessation
- 2004-01-22 KR KR1020057013954A patent/KR20050096165A/ko not_active Ceased
- 2004-01-22 AU AU2004208873A patent/AU2004208873B2/en not_active Ceased
- 2004-01-22 US US10/544,265 patent/US7495096B2/en not_active Expired - Fee Related
- 2004-01-22 AT AT04704202T patent/ATE407135T1/de active
- 2004-01-22 DK DK04704202T patent/DK1590351T3/da active
- 2004-01-22 PL PL378406A patent/PL378406A1/pl not_active Application Discontinuation
- 2004-01-22 DE DE502004007980T patent/DE502004007980D1/de not_active Expired - Lifetime
- 2004-01-22 EP EP04704202A patent/EP1590351B1/de not_active Expired - Lifetime
- 2004-01-22 MX MXPA05008179A patent/MXPA05008179A/es active IP Right Grant
- 2004-01-22 BR BR0407012-7A patent/BRPI0407012A/pt not_active Application Discontinuation
- 2004-01-22 CN CNB2004800034182A patent/CN100558727C/zh not_active Expired - Fee Related
- 2004-01-22 JP JP2006501573A patent/JP2006516578A/ja active Pending
- 2004-01-22 WO PCT/EP2004/000485 patent/WO2004069836A1/de not_active Ceased
- 2004-01-22 CA CA002514945A patent/CA2514945A1/en not_active Abandoned
- 2004-01-22 PT PT04704202T patent/PT1590351E/pt unknown
- 2004-01-22 UA UAA200507716A patent/UA81287C2/uk unknown
- 2004-01-22 SI SI200430943T patent/SI1590351T1/sl unknown
- 2004-01-28 AR ARP040100246A patent/AR042946A1/es unknown
- 2004-01-30 MY MYPI20040294A patent/MY141734A/en unknown
- 2004-02-02 TW TW093102290A patent/TW200418811A/zh unknown
-
2005
- 2005-06-24 ZA ZA200505160A patent/ZA200505160B/en unknown
- 2005-07-29 NO NO20053689A patent/NO20053689L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004208873A1 (en) | 2004-08-19 |
| PL378406A1 (pl) | 2006-04-03 |
| DE10304141A1 (de) | 2004-08-26 |
| CA2514945A1 (en) | 2004-08-19 |
| ES2314366T3 (es) | 2009-03-16 |
| KR20050096165A (ko) | 2005-10-05 |
| EP1590351B1 (de) | 2008-09-03 |
| AU2004208873B2 (en) | 2009-12-17 |
| PT1590351E (pt) | 2008-11-21 |
| WO2004069836A1 (de) | 2004-08-19 |
| EA200501135A1 (ru) | 2006-02-24 |
| TW200418811A (en) | 2004-10-01 |
| DE502004007980D1 (de) | 2008-10-16 |
| DE10304141B4 (de) | 2006-03-09 |
| US7495096B2 (en) | 2009-02-24 |
| NO20053689L (no) | 2005-07-29 |
| NZ541101A (en) | 2009-03-31 |
| SI1590351T1 (sl) | 2009-02-28 |
| AR042946A1 (es) | 2005-07-06 |
| UA81287C2 (en) | 2007-12-25 |
| CN1745084A (zh) | 2006-03-08 |
| ATE407135T1 (de) | 2008-09-15 |
| MY141734A (en) | 2010-06-15 |
| CN100558727C (zh) | 2009-11-11 |
| JP2006516578A (ja) | 2006-07-06 |
| DK1590351T3 (da) | 2008-12-15 |
| EP1590351A1 (de) | 2005-11-02 |
| HK1075898A1 (zh) | 2005-12-30 |
| BRPI0407012A (pt) | 2006-01-10 |
| ZA200505160B (en) | 2007-01-31 |
| US20060084669A1 (en) | 2006-04-20 |
| EA009047B1 (ru) | 2007-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |