[go: up one dir, main page]

DE60321801D1 - Sphäroide, deren herstellungsverfahren und sphäroidenhaltige arzneimittel - Google Patents

Sphäroide, deren herstellungsverfahren und sphäroidenhaltige arzneimittel

Info

Publication number
DE60321801D1
DE60321801D1 DE60321801T DE60321801T DE60321801D1 DE 60321801 D1 DE60321801 D1 DE 60321801D1 DE 60321801 T DE60321801 T DE 60321801T DE 60321801 T DE60321801 T DE 60321801T DE 60321801 D1 DE60321801 D1 DE 60321801D1
Authority
DE
Germany
Prior art keywords
sphroides
medicaments
spheres
sodium
manufacturing processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321801T
Other languages
English (en)
Inventor
Philippe Chenevier
Dominique Marechal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethypharm SAS
Original Assignee
Ethypharm SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm SAS filed Critical Ethypharm SAS
Application granted granted Critical
Publication of DE60321801D1 publication Critical patent/DE60321801D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60321801T 2002-10-04 2003-10-03 Sphäroide, deren herstellungsverfahren und sphäroidenhaltige arzneimittel Expired - Lifetime DE60321801D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0212333A FR2845289B1 (fr) 2002-10-04 2002-10-04 Spheroides, procede de preparation et compositions pharmaceutiques.
PCT/FR2003/002909 WO2004030657A1 (fr) 2002-10-04 2003-10-03 Spheroides procede de preparation et compositions pharmaceutiques

Publications (1)

Publication Number Publication Date
DE60321801D1 true DE60321801D1 (de) 2008-08-07

Family

ID=32011398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60321801T Expired - Lifetime DE60321801D1 (de) 2002-10-04 2003-10-03 Sphäroide, deren herstellungsverfahren und sphäroidenhaltige arzneimittel

Country Status (16)

Country Link
US (2) US20060165794A1 (de)
EP (1) EP1549298B1 (de)
JP (1) JP4660192B2 (de)
CN (1) CN1713896B (de)
AT (1) ATE399001T1 (de)
AU (1) AU2003283492A1 (de)
CA (1) CA2501294C (de)
CY (1) CY1108285T1 (de)
DE (1) DE60321801D1 (de)
DK (1) DK1549298T3 (de)
ES (1) ES2307993T3 (de)
FR (1) FR2845289B1 (de)
MX (1) MXPA05003588A (de)
PT (1) PT1549298E (de)
SI (1) SI1549298T1 (de)
WO (1) WO2004030657A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621187A1 (de) * 2004-07-26 2006-02-01 AstraZeneca AB Pharmazeutische multipartikuläre Tablettenzubereitungen und Prozess zu ihrer Herstellung
WO2010008569A1 (en) * 2008-07-17 2010-01-21 Barr Laboratories, Inc. Orally disintegrating solid pharmaceutical dosage forms comprising delayed-release lansoprazole and methods of making and using the same
ES2483744T3 (es) * 2010-04-26 2014-08-07 Dsm Ip Assets B.V. Nuevo sistema de revestimiento
RU2590979C2 (ru) * 2011-02-11 2016-07-10 ЗедЭкс ФАРМА, ЭлЭлСи Составы l-ментола, состоящие из множества частиц, и связанные с ними способы
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
HRP20190210T1 (hr) 2013-04-23 2019-04-05 Zx Pharma, Llc Enterički premazani multipartikulatni pripravak s proteinskim podslojem
ITMI20132066A1 (it) * 2013-12-11 2015-06-12 Farmatron Ltd Sistemi terapeutici a rilascio modificato per la somministrazione orale di mentolo nel trattamento delle malattie intestinali
CA2990230A1 (en) 2015-06-19 2016-12-22 University Of Southern California Compositions and methods for modified nutrient delivery
WO2016205701A1 (en) 2015-06-19 2016-12-22 University Of Southern California Enteral fast access tract platform system
WO2017145146A1 (en) 2016-02-25 2017-08-31 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
IT202100006893A1 (it) * 2021-03-22 2022-09-22 Kolinpharma S P A Una formulazione in forma di microgranuli comprendente un estratto o molecola di origine vegetale avente effetti gastrolesivi o instabilità a ph acido, e una matrice gastroresistente

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
LU86099A1 (fr) * 1985-09-30 1987-04-02 Pharlyse Formes galeniques a liberation prolongee du verapamil,leur fabrication et medicaments les contenant
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US5780055A (en) * 1996-09-06 1998-07-14 University Of Maryland, Baltimore Cushioning beads and tablet comprising the same capable of forming a suspension
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
UA77145C2 (en) 1997-11-05 2006-11-15 Wyeth Corp Extended release dosage formulation
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
FR2774288B1 (fr) * 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
FR2775188B1 (fr) * 1998-02-23 2001-03-09 Lipha Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
US6419954B1 (en) * 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
DE10044299A1 (de) * 2000-09-07 2002-03-21 Roehm Gmbh Multipartikuläre Arzneiform und Verfahren zu ihrer Herstellung
US6544556B1 (en) * 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor

Also Published As

Publication number Publication date
ES2307993T3 (es) 2008-12-01
CA2501294A1 (fr) 2004-04-15
PT1549298E (pt) 2008-09-16
JP2006505540A (ja) 2006-02-16
MXPA05003588A (es) 2005-07-25
SI1549298T1 (sl) 2008-08-31
CN1713896B (zh) 2011-12-28
CN1713896A (zh) 2005-12-28
HK1077023A1 (zh) 2006-02-03
EP1549298B1 (de) 2008-06-25
DK1549298T3 (da) 2008-09-22
AU2003283492A1 (en) 2004-04-23
US20060165794A1 (en) 2006-07-27
ATE399001T1 (de) 2008-07-15
CA2501294C (fr) 2013-03-26
FR2845289A1 (fr) 2004-04-09
CY1108285T1 (el) 2014-02-12
EP1549298A1 (de) 2005-07-06
JP4660192B2 (ja) 2011-03-30
US9446002B2 (en) 2016-09-20
WO2004030657A1 (fr) 2004-04-15
FR2845289B1 (fr) 2004-12-03
US20100203134A1 (en) 2010-08-12

Similar Documents

Publication Publication Date Title
CY1108285T1 (el) Σφαιροειδη, μεθοδος παρασκευης αυτων και φαρμακευτικες συνθεσεις
BR0106912A (pt) Partìculas contendo ingrediente ativo
BRPI0409652A (pt) tablete, embalagem farmacêutica, método de tratamento de doenças, e, método de preparação de um tablete
PE4796A1 (es) Formas de dosificacion de liberacion controlada de azitromicina
BR0315142A (pt) Cápsula, tablete, grânulo ou grânulo fino, e, cápsula de liberação prolongada
ATE508725T1 (de) Verfahren zur herstellung von tabletten
ES2107235T3 (es) Tableta de liberacion prolongada, revestida con pelicula, de astemizol y pseudoefedrina.
AR014753A1 (es) Formulacion farmaceutica que contiene un 2-[[(2-piridinil)metil]sulfinil] bencimidazol que tiene una actividad antiulcerosa, y un proceso para lapreparacion de dicha formulacion
BR0215262A (pt) Formas de dosagem com liberação sustentada de ordem zero e processo para a fabricação das mesmas
ATE380022T1 (de) Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen
BR0206441A (pt) Composição de revestimento de pelìcula, revestimento de pelìcula cobrindo um núcleo farmacêutico, formulação farmacêutica de liberação modificada, e, processos para preparar uma composição de revestimento de pelìcula, um revestimento de pelìcula e uma formulação
BR0213948A (pt) Forma de dosagem de liberação controlada dual
DE502004005154D1 (de) Multipartikuläre arzneiform, enthaltend mucoadhaesiv formulierte peptid- oder protein-wirkstoffe, sowie ein verfahren zur herstellung der arzneiform
DE60223269D1 (de) Darreichungsformen zur modifizierten freisetzung
ATE396712T1 (de) Pharmazeutische zubereitung zur modifizierten freisetzung
WO1998029095A3 (en) Sustained release cisapride mini-tablet formulation
BRPI0412697A (pt) composições farmacêuticas que apresentam um revestimento expansìvel
AR021578A1 (es) Formulacion en perlas de pravastatina con revestimiento enterico
PT1355635E (pt) Novo revestimento de pelicula
DE60116530D1 (de) Prozess zur herstellung einer oralen arzneiform
BR0006072A (pt) Composição impermeável à água, processos e aplicações da mesma
AR013967A1 (es) UNA FORMULACION MEDICAMENTOSA PARA LA ADMINISTRACION ORAL DE PELLET DE DIFUSION CONTROLADA QUE TIENE LIBERACION CONTROLADA DE UN COMPUESTO ACTIVO QUE ES SELECCIONADO DEL ACIDO 1-CICLOPROPIL-7- [(S,S)-2,8-DIAZABICICLO [4.3.0] NON-8-IL ]-6-FLuOR-1,4-DIHIDRO-8-METOXI-4-OXO-3-QUINOLON CARBOXILICO O SALE
PE84399A1 (es) Formas de dosificacion de sertralina de liberacion retardada
WO2005094265A3 (en) Self assembling activation agents targeted using active drug release
BRPI0510694A (pt) composições farmacêuticas compreendendo ingredientes ativos concentrados encapsuladas em gelatina mole

Legal Events

Date Code Title Description
8364 No opposition during term of opposition