[go: up one dir, main page]

AR014753A1 - Formulacion farmaceutica que contiene un 2-[[(2-piridinil)metil]sulfinil] bencimidazol que tiene una actividad antiulcerosa, y un proceso para lapreparacion de dicha formulacion - Google Patents

Formulacion farmaceutica que contiene un 2-[[(2-piridinil)metil]sulfinil] bencimidazol que tiene una actividad antiulcerosa, y un proceso para lapreparacion de dicha formulacion

Info

Publication number
AR014753A1
AR014753A1 ARP990101230A ARP990101230A AR014753A1 AR 014753 A1 AR014753 A1 AR 014753A1 AR P990101230 A ARP990101230 A AR P990101230A AR P990101230 A ARP990101230 A AR P990101230A AR 014753 A1 AR014753 A1 AR 014753A1
Authority
AR
Argentina
Prior art keywords
preparation
methyl
formulation
activity
antiqulcerous
Prior art date
Application number
ARP990101230A
Other languages
English (en)
Original Assignee
Gea Farmaceutisk Fabrick As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR014753(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gea Farmaceutisk Fabrick As filed Critical Gea Farmaceutisk Fabrick As
Publication of AR014753A1 publication Critical patent/AR014753A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Formulacion farmacéutica oral que contiene gránulos compuestos por un centro inerte revestido con una capa que contiene un 2-[[(2-piridinil)metil]sulfinil]bencimidazol con actividad antiniulcerosa, un desintegrante y un tensioactivo en una matriz de una sustancia de revestimiento en fusion queconsiste esencialmente en uno o más ésteres de glicerol y ácidos grasos, una capa separadora y una capa de revestimiento entérico, así como un proceso parala preparacion de dicha formulacionempleando una técnica de revestimiento en fusion para la preparacion de la capa que contiene el bencimidazol.
ARP990101230A 1998-03-20 1999-03-19 Formulacion farmaceutica que contiene un 2-[[(2-piridinil)metil]sulfinil] bencimidazol que tiene una actividad antiulcerosa, y un proceso para lapreparacion de dicha formulacion AR014753A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK199800397A DK173431B1 (da) 1998-03-20 1998-03-20 Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs

Publications (1)

Publication Number Publication Date
AR014753A1 true AR014753A1 (es) 2001-03-28

Family

ID=8093069

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990101230A AR014753A1 (es) 1998-03-20 1999-03-19 Formulacion farmaceutica que contiene un 2-[[(2-piridinil)metil]sulfinil] bencimidazol que tiene una actividad antiulcerosa, y un proceso para lapreparacion de dicha formulacion

Country Status (20)

Country Link
US (1) US6391342B1 (es)
EP (1) EP1061920B1 (es)
AR (1) AR014753A1 (es)
AT (1) ATE218863T1 (es)
AU (1) AU744596B2 (es)
CA (1) CA2323536C (es)
CZ (1) CZ291943B6 (es)
DE (1) DE69901804T2 (es)
DK (2) DK173431B1 (es)
EA (1) EA002502B1 (es)
ES (1) ES2177246T3 (es)
HU (1) HU226580B1 (es)
IS (1) IS2265B (es)
NO (1) NO20004667L (es)
NZ (1) NZ507115A (es)
PL (1) PL192437B1 (es)
TR (1) TR200002696T2 (es)
TW (1) TW529951B (es)
WO (1) WO1999048498A1 (es)
ZA (1) ZA200004757B (es)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039597A1 (en) * 1998-04-20 2002-04-04 Koji Ukai Stabilized compositions containing benzimidazole-type compounds
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
EP1616562A1 (en) 1999-06-07 2006-01-18 ALTANA Pharma AG Novel preparation and administration form comprising an acid-labile active compound
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
ES2168043B1 (es) 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
AR021347A1 (es) 1999-10-20 2002-07-17 Cipla Ltd Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma
WO2001032185A1 (en) * 1999-11-02 2001-05-10 Cipla Ltd. A pharmaceutical composition containing bisphosphonic acid(s) or salt(s) thereof and a process of preparing thereof
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20060034937A1 (en) * 1999-11-23 2006-02-16 Mahesh Patel Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
DE19959419A1 (de) 1999-12-09 2001-06-21 Ratiopharm Gmbh Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
ES2191521B1 (es) * 2000-11-22 2005-02-16 Laboratorios Belmac, S.A. Nueva formulacion galenica del omeprazol en forma de comprimidos, procedimiento para su preparacion y aplicaciones en medicina humana y en veterinaria.
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
WO2004089333A2 (en) * 2003-02-28 2004-10-21 Cadila Healthcare Limited A stable benzimidazole formulation
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
CA2541578C (en) * 2003-10-10 2014-03-25 Ethypharm Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these
CA2552440A1 (en) * 2003-12-30 2005-07-21 Dr. Reddy's Laboratories Ltd. Pharmaceutical composition
US20050181052A1 (en) * 2004-02-17 2005-08-18 Patel Satishkumar A. Lansoprazole microtablets
MXPA06009991A (es) * 2004-03-03 2007-04-10 Teva Pharma Una composicion farmaceutica estable que comprende un farmaco labil acido.
PT1746980E (pt) 2004-05-07 2012-01-25 Nycomed Gmbh Forma de dosagem farmacêutica compreendendo granulados assim como o seu processo de fabrico
WO2006009602A2 (en) * 2004-06-16 2006-01-26 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
EP1971327A4 (en) * 2005-12-16 2009-09-23 Takeda Pharmaceuticals North A PHARMACEUTICAL COMPOSITIONS OF ILAPRAZOLE
WO2007100984A2 (en) * 2006-02-24 2007-09-07 Allergan, Inc. Beads containing pyridin-sulfinyl benzoimidazole sulfonyl phenoxy acetate derivatives
JP2009538901A (ja) * 2006-06-01 2009-11-12 デクセル ファーマ テクノロジーズ エルティーディー． 複式ユニット製薬的製剤
US8486452B2 (en) * 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US20100239681A1 (en) * 2009-03-20 2010-09-23 Biokey, Inc. Controlled Release Particulates Containing Water-Insoluble Drug
WO2010122583A2 (en) 2009-04-24 2010-10-28 Rubicon Research Private Limited Oral pharmaceutical compositions of acid labile substances
EP2319504A1 (en) 2009-11-07 2011-05-11 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical solid dosage form
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
CN103202820B (zh) * 2012-01-11 2016-03-30 浙江亚太药业股份有限公司 一种稳定的兰索拉唑肠溶胶囊及其制备方法
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
WO2016205423A2 (en) 2015-06-15 2016-12-22 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
WO2017145146A1 (en) 2016-02-25 2017-08-31 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy
TWI795381B (zh) 2016-12-21 2023-03-11 比利時商健生藥品公司 作為ｍａｌｔ１抑制劑之吡唑衍生物
US12150945B2 (en) 2018-07-20 2024-11-26 Lipocine Inc. Liver disease
EP3953345B1 (en) 2019-04-11 2023-04-05 Janssen Pharmaceutica NV Pyridine rings containing derivatives as malt1 inhibitors

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
CA1327010C (en) 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
GB2189699A (en) 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
ES2024993A6 (es) 1990-12-31 1992-03-01 Genesis Para La Investigacion Procedimiento de obtencion de un preparado farmaceutico oral conteniendo omeprazol.
TW209174B (es) 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
YU48263B (sh) 1991-06-17 1997-09-30 Byk Gulden Lomberg Chemische Fabrik Gmbh. Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola
DK0519144T3 (da) * 1991-06-21 1998-03-23 Ilsan Ilac Ve Hammaddeleri San Ny galenisk proces for omeprazol indeholdende pellets
SE9200858L (sv) 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
FR2692146B1 (fr) 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
AU4513393A (en) 1992-07-17 1994-02-14 Astra Aktiebolag Pharmaceutical composition containing antiulcer agent
ES2087823B1 (es) 1994-07-13 1997-02-16 Estudes Et Richerches Pharma E Formulacion de microgranulos gastroresistentes de omeprazol y su procedimiento de fabricacion.
ES2094694B1 (es) 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
SE9500478D0 (sv) 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5708017A (en) * 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
CH687810A5 (de) 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
EP1092434B1 (en) 1995-09-21 2004-03-24 Pharma Pass II LLC Novel composition containing lansoprazole and process for its preparation
SE9600072D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
PT101826A (pt) 1996-02-06 1997-09-30 Medinfar Produtos Farmaceutico Processo para a preparacao de microgranulos contendo omeprazole
WO1998040377A1 (en) 1997-03-07 1998-09-17 A/S Gea Farmaceutisk Fabrik Process for the preparation of 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose

Also Published As

Publication number Publication date
DE69901804D1 (de) 2002-07-18
NO20004667L (no) 2000-11-09
EA200000970A1 (ru) 2001-02-26
IS2265B (is) 2007-07-15
DK173431B1 (da) 2000-10-23
CA2323536A1 (en) 1999-09-30
DE69901804T2 (de) 2002-12-12
NZ507115A (en) 2002-09-27
TR200002696T2 (tr) 2000-12-21
ZA200004757B (en) 2001-05-30
US6391342B1 (en) 2002-05-21
EP1061920B1 (en) 2002-06-12
NO20004667D0 (no) 2000-09-19
TW529951B (en) 2003-05-01
EP1061920A1 (en) 2000-12-27
HUP0101178A2 (hu) 2001-08-28
HU226580B1 (en) 2009-04-28
AU2714899A (en) 1999-10-18
WO1999048498A1 (en) 1999-09-30
CZ291943B6 (cs) 2003-06-18
IS5628A (is) 2000-09-13
DK39798A (da) 1999-09-21
DK1061920T3 (da) 2002-07-15
EA002502B1 (ru) 2002-06-27
PL192437B1 (pl) 2006-10-31
CA2323536C (en) 2009-05-19
ATE218863T1 (de) 2002-06-15
PL342840A1 (en) 2001-07-16
CZ20003458A3 (cs) 2001-03-14
ES2177246T3 (es) 2002-12-01
AU744596B2 (en) 2002-02-28

Similar Documents

Publication Publication Date Title
AR014753A1 (es) Formulacion farmaceutica que contiene un 2-[[(2-piridinil)metil]sulfinil] bencimidazol que tiene una actividad antiulcerosa, y un proceso para lapreparacion de dicha formulacion
AR012698A1 (es) Formulacion farmaceutica de omeprazol
AR024492A1 (es) Formas de dosificacion farmaceutica para liberacion controlada que comprenden al menos un impulso ciclico
ES2167891T3 (es) Estabilizacion de bencimidazoles sensibles a los acidos con combinaciones amino/ciclodextrina.
SV2004001556A (es) Preparaciones acidas de insulina con establidad mejorada
ES2189232T3 (es) Microgranulos de omeprazol protegidos gastricamente, procedimiento para su preparacion y preparaciones farmaceuticas.
ES2036457A1 (es) Forma de dosificacion farmaceutica solida oral de liberacion programada y procedimiento de preparacion.
AR017079A1 (es) Una composicion farmaceutica, un procedimiento para la preparacion de la misma, un metodo de tratamiento y su uso.
FI820467L (fi) Farmaceutiska kompositioner som frigoers kontinuerligt
FI920646A0 (fi) Farmaceutiska preparat.
DE69909316D1 (de) Pharmazeutische formulierung mit omeprazol
ATE261303T1 (de) Neues ein säureempfindliches benzimidazol enthaltendes mittel und verfahren zu dessen herstellung
PE58999A1 (es) Tabletas de oxacarbazepina recubiertas de pelicula
CO6501159A2 (es) Formulaciones farmaceuticas de liberación controlada de nitazoxanida
CO5611097A2 (es) Tableta farmaceutica
ATE457719T2 (de) Pharmazeutische zusammensetzungen mit kontrollierter freisetzung für säurelabile arzneimittel
ATE66371T1 (de) Arzneimittelzubereitung mit verzoegerter freisetzung.
PE20060160A1 (es) Formulaciones de tableta recubierta que comprenden peliglitazar o muraglitazar y procedimiento
NO992098L (no) Preparat med regulert avgivelse av aktiv forbindelse
CO5160317A1 (es) Microgranulos de sulfato de morfina, procedimiento para su preparacion y composicion que los contiene
FR2845289B1 (fr) Spheroides, procede de preparation et compositions pharmaceutiques.
CA2393483A1 (en) Stable pharmaceutical preparations comprising a benzimidazole and process for their production

Legal Events

Date Code Title Description
FA Abandonment or withdrawal