DE60307875D1 - Imidazopyrin-derivate, verfahren zu ihrer herstellung and sie enthaltende pharmazeutische zusamensetzungen - Google Patents

Imidazopyrin-derivate, verfahren zu ihrer herstellung and sie enthaltende pharmazeutische zusamensetzungen

Info

Publication number: DE60307875D1
Authority: DE; Germany
Prior art keywords: imidazopyrine; derivatives; preparation; pharmaceutical compositions; compositions containing
Prior art date: 2002-11-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60307875T

Other languages

English (en)

Other versions

DE60307875T2 (de

Inventor

Sylvain Rault

Jean-Charles Lancelot

Marina Kopp

Daniel-Henri Caignard

Bruno Pfeiffer

Pierre Renard

Jean-Guy Bizot-Espiard

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Les Laboratoires Servier SAS

Original Assignee

Les Laboratoires Servier SAS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-05

Filing date

2003-11-04

Publication date

2006-10-05

2003-11-04 Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS

2006-10-05 Publication of DE60307875D1 publication Critical patent/DE60307875D1/de

2007-04-12 Application granted granted Critical

2007-04-12 Publication of DE60307875T2 publication Critical patent/DE60307875T2/de

2023-11-05 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DE60307875T 2002-11-05 2003-11-04 Imidazopyrin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusamensetzungen Expired - Fee Related DE60307875T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0213802A FR2846656B1 (fr)	2002-11-05	2002-11-05	Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR0213802		2002-11-05
PCT/FR2003/003277 WO2004043957A1 (fr)	2002-11-05	2003-11-04	Derives d’imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number	Publication Date
DE60307875D1 true DE60307875D1 (de)	2006-10-05
DE60307875T2 DE60307875T2 (de)	2007-04-12

Family

ID=32104440

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60307875T Expired - Fee Related DE60307875T2 (de)	2002-11-05	2003-11-04	Imidazopyrin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusamensetzungen

Country Status (26)

Country	Link
US (1)	US7098220B2 (de)
EP (1)	EP1558612B1 (de)
JP (1)	JP2006508111A (de)
KR (1)	KR100717488B1 (de)
CN (1)	CN100335480C (de)
AR (1)	AR041882A1 (de)
AT (1)	ATE337317T1 (de)
AU (1)	AU2003292323A1 (de)
BR (1)	BR0315800A (de)
CA (1)	CA2504008A1 (de)
CY (1)	CY1105752T1 (de)
DE (1)	DE60307875T2 (de)
DK (1)	DK1558612T3 (de)
EA (1)	EA008446B1 (de)
ES (1)	ES2271653T3 (de)
FR (1)	FR2846656B1 (de)
MA (1)	MA27411A1 (de)
MX (1)	MXPA05004791A (de)
MY (1)	MY135191A (de)
NO (1)	NO20052710L (de)
NZ (1)	NZ539599A (de)
PL (1)	PL375373A1 (de)
PT (1)	PT1558612E (de)
UA (1)	UA80579C2 (de)
WO (1)	WO2004043957A1 (de)
ZA (1)	ZA200503234B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1754483A1 (de)	2005-08-18	2007-02-21	Merck Sante	Verwendung von Thienopyridonederivativen als AMPK Aktivatoren und pharmazeutische Zusammensetzungen, die diese enthalten
FR2903695B1 (fr)	2006-07-13	2008-10-24	Merck Sante Soc Par Actions Si	Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2008016730A2 (en) *	2006-08-02	2008-02-07	Targeted Molecular Diagnostics, Llc	Compositions and methods for reducing cellular fat
US8163505B2 (en)	2007-05-22	2012-04-24	The Penn State Research Foundation	Methods using PBK1 for identifying agents that treat metabolic disorders
WO2010030360A1 (en) *	2008-09-11	2010-03-18	Arena Pharmaceuticals, Inc.	3H-IMIDAZO[4,5-b]PYRIDIN-5-OL DERIVATIVES USEFUL IN THE TREATMENT OF GPR81 RECEPTOR DISORDERS
WO2010036613A1 (en) *	2008-09-26	2010-04-01	Merck Sharp & Dohme Corp.	Novel cyclic benzimidazole derivatives useful anti-diabetic agents
CA2741125A1 (en)	2008-10-22	2010-04-29	Merck Sharp & Dohme Corp.	Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010051206A1 (en) *	2008-10-31	2010-05-06	Merck Sharp & Dohme Corp.	Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010103040A1 (en)	2009-03-10	2010-09-16	INSERM (Institut National de la Santé et de la Recherche Médicale)	5'-adenosine monophosphate-activated protein kinase (ampk) activators for treating pulmonary hypertension
CA2779088A1 (en)	2009-11-16	2011-05-19	Mellitech	[1,5]-diazocin derivatives
US8895596B2 (en)	2010-02-25	2014-11-25	Merck Sharp & Dohme Corp	Cyclic benzimidazole derivatives useful as anti-diabetic agents
CN103209981B (zh) *	2010-09-10	2016-12-28	盐野义制药株式会社	具有ampk活化作用的杂环稠合咪唑衍生物
US8889730B2 (en)	2012-04-10	2014-11-18	Pfizer Inc.	Indole and indazole compounds that activate AMPK
US9527839B2 (en)	2012-08-22	2016-12-27	Merck Sharp & Dohme Corp.	Benzimidazole tetrahydropyran derivatives
EP2970277B1 (de) *	2013-03-15	2021-07-28	Knopp Biosciences LLC	Imidazo(4,5-b)pyridin-2-yl-amide als kv7-kanalaktivatoren
CA2905242C (en)	2013-03-15	2016-11-29	Pfizer Inc.	Indole compounds that activate ampk
RS64708B1 (sr)	2014-09-12	2023-11-30	Biohaven Therapeutics Ltd	Benzoimidazol-1,2-il amidi kao aktivatori kv7 kanala
WO2023044364A1 (en)	2021-09-15	2023-03-23	Enko Chem, Inc.	Protoporphyrinogen oxidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2707984B1 (fr) *	1993-07-23	1995-09-01	Adir	Nouvelles pipérazines substituées, leur procédé de préparation et les compositions les contenant.
MXPA03006730A (es) *	1996-12-11	2003-10-24	Aventis Pharma Inc	Preparacion de 4-hidroxi-3-nitro-2(1h)-piridona.
AU760020B2 (en) *	1998-08-31	2003-05-08	Merck & Co., Inc.	Novel angiogenesis inhibitors
US6271241B1 (en) *	1999-04-02	2001-08-07	Neurogen Corporation	Cycloalkyl and aryl fused aminoalkyl-imidazole derivatives: modulators and GLP-1 receptors

2002
- 2002-11-05 FR FR0213802A patent/FR2846656B1/fr not_active Expired - Fee Related
2003
- 2003-04-11 UA UAA200505316A patent/UA80579C2/uk unknown
- 2003-10-09 MY MYPI20033845A patent/MY135191A/en unknown
- 2003-11-04 AU AU2003292323A patent/AU2003292323A1/en not_active Abandoned
- 2003-11-04 NZ NZ539599A patent/NZ539599A/en unknown
- 2003-11-04 EA EA200500717A patent/EA008446B1/ru not_active IP Right Cessation
- 2003-11-04 AR ARP030104024A patent/AR041882A1/es not_active Application Discontinuation
- 2003-11-04 PL PL03375373A patent/PL375373A1/xx not_active Application Discontinuation
- 2003-11-04 KR KR1020057007914A patent/KR100717488B1/ko not_active Expired - Fee Related
- 2003-11-04 EP EP03767889A patent/EP1558612B1/de not_active Expired - Lifetime
- 2003-11-04 US US10/533,699 patent/US7098220B2/en not_active Expired - Fee Related
- 2003-11-04 AT AT03767889T patent/ATE337317T1/de not_active IP Right Cessation
- 2003-11-04 CA CA002504008A patent/CA2504008A1/fr not_active Abandoned
- 2003-11-04 ES ES03767889T patent/ES2271653T3/es not_active Expired - Lifetime
- 2003-11-04 JP JP2004550729A patent/JP2006508111A/ja active Pending
- 2003-11-04 PT PT03767889T patent/PT1558612E/pt unknown
- 2003-11-04 MX MXPA05004791A patent/MXPA05004791A/es active IP Right Grant
- 2003-11-04 DE DE60307875T patent/DE60307875T2/de not_active Expired - Fee Related
- 2003-11-04 DK DK03767889T patent/DK1558612T3/da active
- 2003-11-04 CN CNB2003801027143A patent/CN100335480C/zh not_active Expired - Fee Related
- 2003-11-04 BR BR0315800-4A patent/BR0315800A/pt not_active IP Right Cessation
- 2003-11-04 WO PCT/FR2003/003277 patent/WO2004043957A1/fr not_active Ceased
2005
- 2005-04-19 MA MA28233A patent/MA27411A1/fr unknown
- 2005-04-21 ZA ZA200503234A patent/ZA200503234B/en unknown
- 2005-06-06 NO NO20052710A patent/NO20052710L/no not_active Application Discontinuation
2006
- 2006-11-02 CY CY20061101581T patent/CY1105752T1/el unknown

Also Published As

Publication number	Publication date
CN1711261A (zh)	2005-12-21
FR2846656A1 (fr)	2004-05-07
MY135191A (en)	2008-02-29
MA27411A1 (fr)	2005-06-01
EA008446B1 (ru)	2007-06-29
DK1558612T3 (da)	2006-12-27
ES2271653T3 (es)	2007-04-16
ATE337317T1 (de)	2006-09-15
BR0315800A (pt)	2005-09-20
US7098220B2 (en)	2006-08-29
KR20050084663A (ko)	2005-08-26
MXPA05004791A (es)	2005-07-22
JP2006508111A (ja)	2006-03-09
PT1558612E (pt)	2006-12-29
CA2504008A1 (fr)	2004-05-27
FR2846656B1 (fr)	2004-12-24
CN100335480C (zh)	2007-09-05
HK1081964A1 (en)	2006-05-26
US20060069117A1 (en)	2006-03-30
EP1558612A1 (de)	2005-08-03
AU2003292323A1 (en)	2004-06-03
NZ539599A (en)	2007-06-29
KR100717488B1 (ko)	2007-05-14
EA200500717A1 (ru)	2005-10-27
PL375373A1 (en)	2005-11-28
NO20052710L (no)	2005-06-06
EP1558612B1 (de)	2006-08-23
ZA200503234B (en)	2006-06-28
WO2004043957A1 (fr)	2004-05-27
CY1105752T1 (el)	2010-12-22
DE60307875T2 (de)	2007-04-12
UA80579C2 (en)	2007-10-10
AR041882A1 (es)	2005-06-01

Similar Documents

Publication	Publication Date	Title
ATE252562T1 (de)	2003-11-15	Pyrazolcarbonsäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60215851D1 (de)	2006-12-14	N-adamantylmethyl-derivate und zwischenprodukte als pharmazeutische zusammensetzungen und verfahren zu ihrer herstellung
DE60307875D1 (de)	2006-10-05	Imidazopyrin-derivate, verfahren zu ihrer herstellung and sie enthaltende pharmazeutische zusamensetzungen
DE602004029236D1 (de)	2010-11-04	Cyclische harnstoffderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung als kinaseinhibitoren
DE60014918D1 (de)	2004-11-18	Indol-verbindungen, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zusammensetzungen und ihre medizinische anwendung
DE60325461D1 (de)	2009-02-05	Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung
DE60304599D1 (de)	2006-05-24	Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60318167D1 (de)	2008-01-31	Arzneiform und Verfahren zu ihrer Herstellung
DE60301570D1 (de)	2005-10-13	1,2,3-substituierte indolizinderivate, fgf inhibitoren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE60036102D1 (de)	2007-10-04	Purinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE60110278D1 (de)	2005-06-02	4-Sulfonamid-Piperidin-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DE60022890D1 (de)	2006-02-09	Naphthyridine derivate, verfahren zu ihrer herstellung, deren anwendung und sie enthaltende pharmazeutische zusammensetzungen
DE60010113D1 (de)	2004-05-27	N-guanidinalkylamide, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate
DE60033519D1 (de)	2007-04-05	Morphinsulfat enthaltende mikrogranulate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen
ATE222586T1 (de)	2002-09-15	Benzolsulfonamidderivate und verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE602006000102D1 (de)	2007-10-25	Indanyl-piperazinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE60200023D1 (de)	2003-10-02	Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen
ATE275136T1 (de)	2004-09-15	Morpholinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE60300571D1 (de)	2005-06-02	[3,4-a:3,4-c]Carbazolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE60036081D1 (de)	2007-10-04	(1-phenacyl-3-phenyl-3-piperidylethyl)piperidinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE60222515D1 (de)	2007-10-31	BenzoÄbÜpyranoÄ3,2-hÜacridin-7-on Derivative, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE60130676D1 (de)	2007-11-08	Cyclohexyl(alkyl)-propanolamine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60100690D1 (de)	2003-10-09	Benzothiadiazinderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE60007168D1 (de)	2004-01-22	Benzopyranyl-guanidin-derivate, verfahren zu deren herstellung sowie diese enthaltenden pharmazeutische zusammensetzungen
DE60205424D1 (de)	2005-09-15	Pyrimidin-4-one Derivate, Verfahren zu ihrer Herstellung and sie enthaltende Zusammensetzungen

Legal Events

Date	Code	Title	Description
2007-09-13	8364	No opposition during term of opposition
2009-09-17	8339	Ceased/non-payment of the annual fee