DE60200023D1 - Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen - Google Patents

Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen

Info

Publication number: DE60200023D1
Authority: DE; Germany
Prior art keywords: isoindoloindolone; derivatives; preparation; pharmaceutical compositions; compositions containing
Prior art date: 2001-03-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60200023T

Other languages

English (en)

Other versions

DE60200023T2 (de

Inventor

Michel Wierzbicki

Marie-Francoise Boussard

Anne Rousseau

Jean-Albert Boutin

Philippe Delagrange

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Les Laboratoires Servier SAS

Original Assignee

Les Laboratoires Servier SAS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-12

Filing date

2002-03-11

Publication date

2003-10-02

2002-03-11 Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS

2003-10-02 Application granted granted Critical

2003-10-02 Publication of DE60200023D1 publication Critical patent/DE60200023D1/de

2004-06-03 Publication of DE60200023T2 publication Critical patent/DE60200023T2/de

2022-03-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Psychology (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DE60200023T 2001-03-12 2002-03-11 Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen Expired - Fee Related DE60200023T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0103293A FR2821843B1 (fr)	2001-03-12	2001-03-12	Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR0103293		2001-03-12

Publications (2)

Publication Number	Publication Date
DE60200023D1 true DE60200023D1 (de)	2003-10-02
DE60200023T2 DE60200023T2 (de)	2004-06-03

Family

ID=8860976

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60200023T Expired - Fee Related DE60200023T2 (de)	2001-03-12	2002-03-11	Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen

Country Status (24)

Country	Link
US (1)	US6465660B1 (de)
EP (1)	EP1241169B1 (de)
JP (1)	JP3842151B2 (de)
KR (1)	KR100450313B1 (de)
CN (1)	CN1159316C (de)
AR (1)	AR034583A1 (de)
AT (1)	ATE248171T1 (de)
AU (1)	AU779702B2 (de)
BR (1)	BR0200721A (de)
CA (1)	CA2376876C (de)
DE (1)	DE60200023T2 (de)
DK (1)	DK1241169T3 (de)
EA (1)	EA004035B1 (de)
ES (1)	ES2206438T3 (de)
FR (1)	FR2821843B1 (de)
HK (1)	HK1049000B (de)
HU (1)	HUP0200913A3 (de)
MX (1)	MXPA02002601A (de)
NO (1)	NO20021198L (de)
NZ (1)	NZ517742A (de)
PL (1)	PL352750A1 (de)
PT (1)	PT1241169E (de)
SI (1)	SI1241169T1 (de)
ZA (1)	ZA200202030B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2826009B1 (fr) *	2001-06-13	2003-08-15	Servier Lab	Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE60309324T2 (de) *	2002-06-21	2007-05-10	Suven Life Sciences Ltd.	Tetracyclische arylcarbonyl indole mit serotoninrezeptoraffinität als arzneimittel, verfahren zu ihrer herstellung und pharmazeutische zubereitungen
US7297711B2 (en) *	2002-06-21	2007-11-20	Suven Life Sciences Limited	Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
BRPI0315958B8 (pt) *	2002-11-28	2021-05-25	Suven Life Sciences Ltd	composto, composição farmacêutica, processo para a preparação de um composto, novos intermediários e uso do composto
SI1581538T1 (sl) *	2002-12-18	2007-08-31	Suven Life Sciences Ltd	Tetraciklični 3-substituirani indoli z afiniteto za receptor serotonina
RU2387655C2 (ru) *	2004-08-09	2010-04-27	Бристол-Маерс Сквибб Компани	Ингибиторы репликации вируса гепатита с
ES2580702B1 (es)	2015-02-25	2017-06-08	Palobiofarma, S.L.	Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina
AU2023333524A1 (en)	2022-09-02	2025-04-03	Dexcom, Inc.	Continuous analyte sensor devices and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5377098A (en) *	1976-12-16	1978-07-08	Sumitomo Chem Co Ltd	Preparation of indoloisoquinoline derivative
US4452808A (en) *	1982-12-07	1984-06-05	Smithkline Beckman Corporation	4-Aminoalkyl-2(3H)-indolones
US5441955A (en) *	1993-11-19	1995-08-15	Pathogenesis Corporation	Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof
FR2743365A1 (fr) *	1996-01-10	1997-07-11	Rhone Poulenc Rorer Sa	Derives de 5h,10h-imidazo(1,2-a)indolo(3,2-e)pyrazine-4-one, leur preparation et les medicaments les contenant
US20020040018A1 (en) *	2000-06-23	2002-04-04	Jones Robert M.	Subtype selective melatonergics

2001
- 2001-03-12 FR FR0103293A patent/FR2821843B1/fr not_active Expired - Fee Related
2002
- 2002-02-26 US US10/083,074 patent/US6465660B1/en not_active Expired - Fee Related
- 2002-03-09 KR KR10-2002-0012699A patent/KR100450313B1/ko not_active Expired - Fee Related
- 2002-03-11 NO NO20021198A patent/NO20021198L/no not_active Application Discontinuation
- 2002-03-11 EP EP02290598A patent/EP1241169B1/de not_active Expired - Lifetime
- 2002-03-11 NZ NZ517742A patent/NZ517742A/xx unknown
- 2002-03-11 CA CA002376876A patent/CA2376876C/fr not_active Expired - Fee Related
- 2002-03-11 AT AT02290598T patent/ATE248171T1/de not_active IP Right Cessation
- 2002-03-11 DK DK02290598T patent/DK1241169T3/da active
- 2002-03-11 SI SI200230002T patent/SI1241169T1/xx unknown
- 2002-03-11 JP JP2002065233A patent/JP3842151B2/ja not_active Expired - Fee Related
- 2002-03-11 HU HU0200913A patent/HUP0200913A3/hu unknown
- 2002-03-11 EA EA200200241A patent/EA004035B1/ru unknown
- 2002-03-11 AR ARP020100863A patent/AR034583A1/es active IP Right Grant
- 2002-03-11 ES ES02290598T patent/ES2206438T3/es not_active Expired - Lifetime
- 2002-03-11 BR BR0200721-5A patent/BR0200721A/pt not_active IP Right Cessation
- 2002-03-11 DE DE60200023T patent/DE60200023T2/de not_active Expired - Fee Related
- 2002-03-11 MX MXPA02002601A patent/MXPA02002601A/es active IP Right Grant
- 2002-03-11 PT PT02290598T patent/PT1241169E/pt unknown
- 2002-03-12 AU AU23242/02A patent/AU779702B2/en not_active Ceased
- 2002-03-12 CN CNB021070547A patent/CN1159316C/zh not_active Expired - Fee Related
- 2002-03-12 PL PL02352750A patent/PL352750A1/xx not_active Application Discontinuation
- 2002-03-12 ZA ZA200202030A patent/ZA200202030B/xx unknown
2003
- 2003-02-18 HK HK03101182.3A patent/HK1049000B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0200913A2 (hu)	2002-11-28
US6465660B1 (en)	2002-10-15
ES2206438T3 (es)	2004-05-16
FR2821843B1 (fr)	2003-05-09
EP1241169B1 (de)	2003-08-27
PT1241169E (pt)	2003-11-28
FR2821843A1 (fr)	2002-09-13
DE60200023T2 (de)	2004-06-03
EP1241169A1 (de)	2002-09-18
ZA200202030B (en)	2002-10-03
EA200200241A1 (ru)	2002-10-31
JP2002265469A (ja)	2002-09-18
HK1049000B (zh)	2005-01-07
ATE248171T1 (de)	2003-09-15
CN1159316C (zh)	2004-07-28
NO20021198D0 (no)	2002-03-11
HU0200913D0 (de)	2002-05-29
KR20020072782A (ko)	2002-09-18
JP3842151B2 (ja)	2006-11-08
NZ517742A (en)	2003-02-28
CA2376876A1 (fr)	2002-09-12
KR100450313B1 (ko)	2004-09-30
PL352750A1 (en)	2002-09-23
AU779702B2 (en)	2005-02-10
EA004035B1 (ru)	2003-12-25
BR0200721A (pt)	2002-12-03
DK1241169T3 (da)	2003-11-24
CN1375494A (zh)	2002-10-23
HUP0200913A3 (en)	2004-11-29
NO20021198L (no)	2002-09-13
SI1241169T1 (en)	2003-12-31
AU2324202A (en)	2002-09-19
AR034583A1 (es)	2004-03-03
CA2376876C (fr)	2006-07-11
HK1049000A1 (en)	2003-04-25
MXPA02002601A (es)	2004-11-12

Publication	Publication Date	Title
ATE344034T1 (de)	2006-11-15	N-adamantylmethyl-derivate und zwischenprodukte als pharmazeutische zusammensetzungen und verfahren zu ihrer herstellung
ATE252562T1 (de)	2003-11-15	Pyrazolcarbonsäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
HUP0402225A3 (en)	2006-01-30	Macrolide-compounds, process for their preparation and pharmaceutical compositions containing them
ATE323092T1 (de)	2006-04-15	Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60318167D1 (de)	2008-01-31	Arzneiform und Verfahren zu ihrer Herstellung
DE60301570D1 (de)	2005-10-13	1,2,3-substituierte indolizinderivate, fgf inhibitoren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE60307875D1 (de)	2006-10-05	Imidazopyrin-derivate, verfahren zu ihrer herstellung and sie enthaltende pharmazeutische zusamensetzungen
ATE294175T1 (de)	2005-05-15	4-sulfonamid-piperidin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE60203178D1 (de)	2005-04-14	Pharmazeutische formulierung mit überdecktem geschmack und verfahren zu ihrer herstellung
DE60010113D1 (de)	2004-05-27	N-guanidinalkylamide, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate
DE60033519D1 (de)	2007-04-05	Morphinsulfat enthaltende mikrogranulate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen
DE60022890D1 (de)	2006-02-09	Naphthyridine derivate, verfahren zu ihrer herstellung, deren anwendung und sie enthaltende pharmazeutische zusammensetzungen
ATE222586T1 (de)	2002-09-15	Benzolsulfonamidderivate und verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
HUP0302429A3 (en)	2004-01-28	4-amino-quinazolines, process for producing them, pharmaceutical compositions containing them and their use
DE60200023D1 (de)	2003-10-02	Isoindoloindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltende pharmazeutische Zusammensetzungen
DE60200041D1 (de)	2003-10-30	Indenoindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltenden pharmazeutischen Zusammensetzungen
DE60003662D1 (de)	2003-08-07	Pyridothienodiazepine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
HUP0203859A3 (en)	2008-01-28	Aminomethyl-phenyl-cyclohexanone derivatives, process for their preparation, pharmaceutical compositions containing them and their use
ATE275136T1 (de)	2004-09-15	Morpholinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
ATE374177T1 (de)	2007-10-15	Cyclohexyl(alkyl)-propanolamine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60222515D1 (de)	2007-10-31	BenzoÄbÜpyranoÄ3,2-hÜacridin-7-on Derivative, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
ATE295358T1 (de)	2005-05-15	N-benzylpiperazin n-benzylpiperazine, verbindungen, verfahren zu deren herstellung und deren pharmazeutischen zusammensetzungen
HUP0401038A3 (en)	2011-08-29	Piperazinylcarbonylquinolines and -isoquinolines, process for their preparation and pharmaceutical compositions containing them
ATE286877T1 (de)	2005-01-15	Benzolsulfonamidderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60300307D1 (de)	2005-03-10	Imidazolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Legal Events

Date	Code	Title	Description
2004-09-23	8364	No opposition during term of opposition
2011-01-20	8339	Ceased/non-payment of the annual fee