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DE602006006908D1 - Inhibitoren der löslichen Adenylatzyklase - Google Patents

Inhibitoren der löslichen Adenylatzyklase

Info

Publication number
DE602006006908D1
DE602006006908D1 DE602006006908T DE602006006908T DE602006006908D1 DE 602006006908 D1 DE602006006908 D1 DE 602006006908D1 DE 602006006908 T DE602006006908 T DE 602006006908T DE 602006006908 T DE602006006908 T DE 602006006908T DE 602006006908 D1 DE602006006908 D1 DE 602006006908D1
Authority
DE
Germany
Prior art keywords
inhibitors
adenylate cyclase
soluble adenylate
soluble
cyclase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602006006908T
Other languages
English (en)
Inventor
Bernd Buchmann
Duy Nguyen
Martin Fritsch
Bernd Menzenbach
Ulf Boemer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of DE602006006908D1 publication Critical patent/DE602006006908D1/de
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
DE602006006908T 2005-06-08 2006-06-07 Inhibitoren der löslichen Adenylatzyklase Expired - Fee Related DE602006006908D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005027274A DE102005027274A1 (de) 2005-06-08 2005-06-08 Inhibitoren der löslichen Adenylatzyklase
PCT/EP2006/005608 WO2006131398A2 (en) 2005-06-08 2006-06-07 Inhibitors of soluble adenylate cyclase

Publications (1)

Publication Number Publication Date
DE602006006908D1 true DE602006006908D1 (de) 2009-07-02

Family

ID=37398540

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102005027274A Withdrawn DE102005027274A1 (de) 2005-06-08 2005-06-08 Inhibitoren der löslichen Adenylatzyklase
DE602006006908T Expired - Fee Related DE602006006908D1 (de) 2005-06-08 2006-06-07 Inhibitoren der löslichen Adenylatzyklase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE102005027274A Withdrawn DE102005027274A1 (de) 2005-06-08 2005-06-08 Inhibitoren der löslichen Adenylatzyklase

Country Status (23)

Country Link
EP (1) EP1888058B1 (de)
JP (1) JP2008542422A (de)
KR (1) KR20080016617A (de)
CN (1) CN101193631A (de)
AR (1) AR054378A1 (de)
AT (1) ATE431736T1 (de)
AU (1) AU2006256857A1 (de)
BR (1) BRPI0610934A2 (de)
CA (1) CA2606692A1 (de)
CR (1) CR9578A (de)
DE (2) DE102005027274A1 (de)
DO (1) DOP2006000130A (de)
EA (1) EA200702590A1 (de)
EC (1) ECSP078024A (de)
GT (1) GT200600244A (de)
IL (1) IL186914A0 (de)
MX (1) MX2007015493A (de)
NO (1) NO20080104L (de)
PE (1) PE20061488A1 (de)
TW (1) TW200716090A (de)
UY (1) UY29583A1 (de)
WO (1) WO2006131398A2 (de)
ZA (1) ZA200800153B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006014319B4 (de) * 2006-03-23 2009-01-08 Bayer Schering Pharma Aktiengesellschaft Inhibitoren der löslichen Adenylatzyklase
EP2036906A1 (de) * 2007-09-05 2009-03-18 Bayer Schering Pharma Aktiengesellschaft Azaindole als Inhibitoren der löslichen Adenylatzyklase
WO2023100061A1 (en) 2021-12-01 2023-06-08 Pfizer Inc. 3-phenyl-1-benzothiophene-2-carboxylic acid derivatives as branched-chain alpha keto acid dehydrogenase kinase inhibitors for the treatment of diabetes, kidney diseases, nash and heart failure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635776B1 (fr) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie Derives amides, procede pour leur fabrication et compositions fongicides les contenant
AU2001287060A1 (en) * 2000-09-05 2002-03-22 University Of Virginia Patent Foundation Human soluble testicular adenylyl cyclase
UA75660C2 (en) * 2001-06-28 2006-05-15 Pfizer Prod Inc Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (mtp) and/or apolipoprotein b (apo b) secretion
AU2002327627B2 (en) * 2001-09-14 2006-09-14 Methylgene Inc. Inhibitors of histone deacetylase
UA79504C2 (en) * 2002-11-07 2007-06-25 Organon Nv Indols for treating diseases associated with androgen receptors
JP4741491B2 (ja) * 2003-08-07 2011-08-03 ライジェル ファーマシューティカルズ, インコーポレイテッド 抗増殖剤としての2,4−ピリミジンジアミン化合物および使用
US7935724B2 (en) * 2003-10-09 2011-05-03 Merck Hdac Research, Llc Thiophene and benzothiophene hydroxamic acid derivatives
CA2553848A1 (en) * 2004-01-21 2005-08-04 Cornell Research Foundation, Inc. Chemical inhibitors of soluble adenylyl cyclase (sac)
WO2005092899A1 (en) * 2004-03-26 2005-10-06 Methylgene Inc. Inhibitors of histone deacetylase
DE102004047272A1 (de) * 2004-09-24 2006-04-06 Schering Ag Inhibitoren der löslichen Adenylatzyklase

Also Published As

Publication number Publication date
KR20080016617A (ko) 2008-02-21
EA200702590A1 (ru) 2008-06-30
ECSP078024A (es) 2008-01-23
AU2006256857A1 (en) 2006-12-14
ATE431736T1 (de) 2009-06-15
UY29583A1 (es) 2007-01-31
NO20080104L (no) 2008-03-03
EP1888058B1 (de) 2009-05-20
PE20061488A1 (es) 2007-02-03
IL186914A0 (en) 2008-02-09
EP1888058A2 (de) 2008-02-20
GT200600244A (es) 2007-01-23
CN101193631A (zh) 2008-06-04
DOP2006000130A (es) 2006-11-30
WO2006131398A2 (en) 2006-12-14
BRPI0610934A2 (pt) 2010-08-03
JP2008542422A (ja) 2008-11-27
CR9578A (es) 2008-03-06
WO2006131398A3 (en) 2007-04-19
AR054378A1 (es) 2007-06-20
DE102005027274A1 (de) 2006-12-14
TW200716090A (en) 2007-05-01
MX2007015493A (es) 2008-02-22
CA2606692A1 (en) 2006-12-14
ZA200800153B (en) 2009-03-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee