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CR9578A - Inhibidores de la adenilato ciclasa soluble - Google Patents

Inhibidores de la adenilato ciclasa soluble

Info

Publication number
CR9578A
CR9578A CR9578A CR9578A CR9578A CR 9578 A CR9578 A CR 9578A CR 9578 A CR9578 A CR 9578A CR 9578 A CR9578 A CR 9578A CR 9578 A CR9578 A CR 9578A
Authority
CR
Costa Rica
Prior art keywords
adenylate
cycling
inhibitors
soluble
medicine
Prior art date
Application number
CR9578A
Other languages
English (en)
Inventor
Bernd Buchmann
Duy Nguyen
Martin Fritsch
Bernd Menzenbach
Ulf Boemer
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of CR9578A publication Critical patent/CR9578A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

La invencion se relaciona con compuestos de la formula general (I), y con su preparacion y su uso como medicamento.
CR9578A 2005-06-08 2007-12-07 Inhibidores de la adenilato ciclasa soluble CR9578A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005027274A DE102005027274A1 (de) 2005-06-08 2005-06-08 Inhibitoren der löslichen Adenylatzyklase

Publications (1)

Publication Number Publication Date
CR9578A true CR9578A (es) 2008-03-06

Family

ID=37398540

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9578A CR9578A (es) 2005-06-08 2007-12-07 Inhibidores de la adenilato ciclasa soluble

Country Status (23)

Country Link
EP (1) EP1888058B1 (es)
JP (1) JP2008542422A (es)
KR (1) KR20080016617A (es)
CN (1) CN101193631A (es)
AR (1) AR054378A1 (es)
AT (1) ATE431736T1 (es)
AU (1) AU2006256857A1 (es)
BR (1) BRPI0610934A2 (es)
CA (1) CA2606692A1 (es)
CR (1) CR9578A (es)
DE (2) DE102005027274A1 (es)
DO (1) DOP2006000130A (es)
EA (1) EA200702590A1 (es)
EC (1) ECSP078024A (es)
GT (1) GT200600244A (es)
IL (1) IL186914A0 (es)
MX (1) MX2007015493A (es)
NO (1) NO20080104L (es)
PE (1) PE20061488A1 (es)
TW (1) TW200716090A (es)
UY (1) UY29583A1 (es)
WO (1) WO2006131398A2 (es)
ZA (1) ZA200800153B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006014319B4 (de) * 2006-03-23 2009-01-08 Bayer Schering Pharma Aktiengesellschaft Inhibitoren der löslichen Adenylatzyklase
EP2036906A1 (de) * 2007-09-05 2009-03-18 Bayer Schering Pharma Aktiengesellschaft Azaindole als Inhibitoren der löslichen Adenylatzyklase
WO2023100061A1 (en) 2021-12-01 2023-06-08 Pfizer Inc. 3-phenyl-1-benzothiophene-2-carboxylic acid derivatives as branched-chain alpha keto acid dehydrogenase kinase inhibitors for the treatment of diabetes, kidney diseases, nash and heart failure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635776B1 (fr) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie Derives amides, procede pour leur fabrication et compositions fongicides les contenant
AU2001287060A1 (en) * 2000-09-05 2002-03-22 University Of Virginia Patent Foundation Human soluble testicular adenylyl cyclase
UA75660C2 (en) * 2001-06-28 2006-05-15 Pfizer Prod Inc Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (mtp) and/or apolipoprotein b (apo b) secretion
AU2002327627B2 (en) * 2001-09-14 2006-09-14 Methylgene Inc. Inhibitors of histone deacetylase
UA79504C2 (en) * 2002-11-07 2007-06-25 Organon Nv Indols for treating diseases associated with androgen receptors
JP4741491B2 (ja) * 2003-08-07 2011-08-03 ライジェル ファーマシューティカルズ， インコーポレイテッド 抗増殖剤としての２，４−ピリミジンジアミン化合物および使用
US7935724B2 (en) * 2003-10-09 2011-05-03 Merck Hdac Research, Llc Thiophene and benzothiophene hydroxamic acid derivatives
CA2553848A1 (en) * 2004-01-21 2005-08-04 Cornell Research Foundation, Inc. Chemical inhibitors of soluble adenylyl cyclase (sac)
WO2005092899A1 (en) * 2004-03-26 2005-10-06 Methylgene Inc. Inhibitors of histone deacetylase
DE102004047272A1 (de) * 2004-09-24 2006-04-06 Schering Ag Inhibitoren der löslichen Adenylatzyklase

Also Published As

Publication number Publication date
KR20080016617A (ko) 2008-02-21
EA200702590A1 (ru) 2008-06-30
ECSP078024A (es) 2008-01-23
AU2006256857A1 (en) 2006-12-14
ATE431736T1 (de) 2009-06-15
UY29583A1 (es) 2007-01-31
NO20080104L (no) 2008-03-03
EP1888058B1 (en) 2009-05-20
PE20061488A1 (es) 2007-02-03
DE602006006908D1 (de) 2009-07-02
IL186914A0 (en) 2008-02-09
EP1888058A2 (en) 2008-02-20
GT200600244A (es) 2007-01-23
CN101193631A (zh) 2008-06-04
DOP2006000130A (es) 2006-11-30
WO2006131398A2 (en) 2006-12-14
BRPI0610934A2 (pt) 2010-08-03
JP2008542422A (ja) 2008-11-27
WO2006131398A3 (en) 2007-04-19
AR054378A1 (es) 2007-06-20
DE102005027274A1 (de) 2006-12-14
TW200716090A (en) 2007-05-01
MX2007015493A (es) 2008-02-22
CA2606692A1 (en) 2006-12-14
ZA200800153B (en) 2009-03-25

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)