DE60133014D1 - H3 agonisten oder antagonisten - Google Patents

H3 agonisten oder antagonisten

Info

Publication number: DE60133014D1
Authority: DE; Germany
Prior art keywords: agonists; antagonists
Prior art date: 2000-09-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60133014T

Other languages

English (en)

Other versions

DE60133014T2 (de

Inventor

Neng-Yang Shih

Daniel M Solomon

John J Piwinski

Andrew T Lupo

Michael J Green

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-20

Filing date

2001-09-18

Publication date

2008-04-10

2001-09-18 Application filed by Schering Corp filed Critical Schering Corp

2008-04-10 Application granted granted Critical

2008-04-10 Publication of DE60133014D1 publication Critical patent/DE60133014D1/de

2009-02-26 Publication of DE60133014T2 publication Critical patent/DE60133014T2/de

2021-09-19 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

DE60133014T 2000-09-20 2001-09-18 Substituierte imidazole als duale histamin h1 und h3 agonisten oder antagonisten Expired - Lifetime DE60133014T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US23405300P	2000-09-20	2000-09-20
US234053P		2000-09-20
PCT/US2001/029095 WO2002024659A2 (en)	2000-09-20	2001-09-18	Substituted imidazoles as dual histamine h1 and h3 agonists or antgonists

Publications (2)

Publication Number	Publication Date
DE60133014D1 true DE60133014D1 (de)	2008-04-10
DE60133014T2 DE60133014T2 (de)	2009-02-26

Family

ID=22879692

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60133014T Expired - Lifetime DE60133014T2 (de)	2000-09-20	2001-09-18	Substituierte imidazole als duale histamin h1 und h3 agonisten oder antagonisten

Country Status (15)

Country	Link
US (1)	US6506756B2 (de)
EP (1)	EP1318994B1 (de)
JP (1)	JP2004509871A (de)
CN (1)	CN1461303A (de)
AR (1)	AR030946A1 (de)
AT (1)	ATE387439T1 (de)
AU (1)	AU2001292730A1 (de)
CA (1)	CA2421826C (de)
DE (1)	DE60133014T2 (de)
ES (1)	ES2300364T3 (de)
HK (1)	HK1052179A1 (de)
MX (1)	MXPA03002448A (de)
MY (1)	MY117975A (de)
TW (1)	TW589303B (de)
WO (1)	WO2002024659A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6607862B2 (en)	2001-08-24	2003-08-19	Intel Corporation	Damascene extreme ultraviolet lithography alternative phase shift photomask and method of making
JP4384918B2 (ja) *	2002-04-18	2009-12-16	シェーリングコーポレイション	ヒスタミンｈ３アンタゴニストとして有用な（１−４−ピペリジニル）ベンズイミダゾール誘導体
NZ535764A (en)	2002-04-18	2007-10-26	Schering Corp	1-(4-piperidinyl) benzimidazolones as histamine H3 antagonists
US7105505B2 (en)	2002-04-18	2006-09-12	Schering Corporation	Benzimidazole derivatives useful as histamine H3 antagonists
NL1026634C2 (nl) *	2004-07-12	2006-01-16	Willem Jacob Van Der Burg	Psychofarmaceutisch preparaat en werkzame stof daarin.
WO2013151982A1 (en)	2012-04-03	2013-10-10	Arena Pharmaceuticals, Inc.	Methods and compounds useful in treating pruritus, and methods for identifying such compounds
US9224955B1 (en) *	2014-10-31	2015-12-29	Feng-wen Yen	Purifying method for organic optoelectronic material
CN113880808B (zh) *	2020-07-03	2024-12-31	合肥医工医药股份有限公司	一类三唑类化合物、制备方法及其医药用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2586562B1 (fr)	1985-09-02	1989-03-10	Inst Nat Sante Rech Med	Composition pharmaceutique contenant de l'a-methylhistamine
ATE108453T1 (de)	1988-04-28	1994-07-15	Schering Corp	Benzopyridopiperidin, -piperidyliden und - piperazin-verbindungen, zusammensetzungen, methoden zur herstellung und verwendung.
GB8916947D0 (en)	1989-07-25	1989-09-13	Smith Kline French Lab	Medicaments
EP0448765B1 (de)	1990-03-30	1994-08-17	HEUMANN PHARMA GMBH & CO	Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels mit NPY-antagonistischer Wirkung
GB9115740D0 (en)	1991-07-20	1991-09-04	Smithkline Beecham Plc	Medicaments
DE69205287T2 (de)	1991-12-18	1996-03-14	Schering Corp., Kenilworth, N.J.	Imidazolylalkyl- piperazin und -diazepin derivate als histamin h3 agonisten/antagonisten.
US5352707A (en)	1992-03-26	1994-10-04	Harbor Branch Oceanographic Institution, Inc.	Method for treating airway congestion
HUT74386A (en)	1993-11-15	1996-12-30	Schering Corp	Phenyl-alkyl imidazoles as h3-receptor antagonists and pharmaceutical compositions containing them
FR2732017B1 (fr)	1995-03-21	2000-09-22	Inst Nat Sante Rech Med	Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques
AU7907198A (en)	1997-06-24	1999-01-04	Novo Nordisk A/S	Use of somatostatin agonists and antagonists for treating diseases related to the eye
US5869479A (en)	1997-08-14	1999-02-09	Schering Corporation	Treatment of upper airway allergic responses
WO2000005215A1 (en) *	1998-07-24	2000-02-03	Russinsky Limited	A process for preparing benzocycloheptapyridin-11-ones

2001
- 2001-09-18 US US09/954,867 patent/US6506756B2/en not_active Expired - Fee Related
- 2001-09-18 AU AU2001292730A patent/AU2001292730A1/en not_active Abandoned
- 2001-09-18 WO PCT/US2001/029095 patent/WO2002024659A2/en not_active Ceased
- 2001-09-18 CA CA002421826A patent/CA2421826C/en not_active Expired - Fee Related
- 2001-09-18 AT AT01973119T patent/ATE387439T1/de not_active IP Right Cessation
- 2001-09-18 EP EP01973119A patent/EP1318994B1/de not_active Expired - Lifetime
- 2001-09-18 AR ARP010104399A patent/AR030946A1/es unknown
- 2001-09-18 HK HK03104436.1A patent/HK1052179A1/zh unknown
- 2001-09-18 MY MYPI20014365A patent/MY117975A/en unknown
- 2001-09-18 CN CN01815978A patent/CN1461303A/zh active Pending
- 2001-09-18 DE DE60133014T patent/DE60133014T2/de not_active Expired - Lifetime
- 2001-09-18 JP JP2002529071A patent/JP2004509871A/ja not_active Withdrawn
- 2001-09-18 ES ES01973119T patent/ES2300364T3/es not_active Expired - Lifetime
- 2001-09-18 MX MXPA03002448A patent/MXPA03002448A/es active IP Right Grant
- 2001-09-19 TW TW090123001A patent/TW589303B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
MY117975A (en)	2004-08-30
EP1318994A2 (de)	2003-06-18
EP1318994B1 (de)	2008-02-27
CA2421826A1 (en)	2002-03-28
TW589303B (en)	2004-06-01
WO2002024659A3 (en)	2002-10-24
JP2004509871A (ja)	2004-04-02
WO2002024659A2 (en)	2002-03-28
MXPA03002448A (es)	2003-06-19
AR030946A1 (es)	2003-09-03
CN1461303A (zh)	2003-12-10
DE60133014T2 (de)	2009-02-26
CA2421826C (en)	2009-10-27
HK1052179A1 (zh)	2003-09-05
ES2300364T3 (es)	2008-06-16
US20020086859A1 (en)	2002-07-04
US6506756B2 (en)	2003-01-14
ATE387439T1 (de)	2008-03-15
AU2001292730A1 (en)	2002-04-02

Publication	Publication Date	Title
NO20025115D0 (no)	2002-10-24	Muskarin agonister
DK1440077T3 (da)	2013-07-08	Syntetiske heparinpentasaccharider
NO20032612D0 (no)	2003-06-10	CXCR3-antagonister
ATE402148T1 (de)	2008-08-15	Substituierte pyridinylamine
DK1226127T3 (da)	2009-10-19	Substituerede phenylsulfamoylcarboxamider
ATE307121T1 (de)	2005-11-15	Substituierte arylpyrazine
ATE439344T1 (de)	2009-08-15	Muscarin-antagonisten
AR028393A1 (es)	2003-05-07	Iminoazidas substituidas
DE50206892D1 (de)	2006-06-29	Substituierte imidazotriazinone
DE60135487D1 (de)	2008-10-02	Codierer
ATE374183T1 (de)	2007-10-15	Nk1-antagonisten
DK1373228T3 (da)	2008-08-04	Substituerede fluoralkoxyphenylsulfonylurinstoffer
DE50112662D1 (de)	2007-08-09	Substituierte benzoylcyclohexenone
DE60324018D1 (de)	2008-11-20	Agonisten
AR028302A1 (es)	2003-05-07	Feniluracilos substituidos
DK1406858T3 (da)	2009-11-23	Substituerede 4-aminocyklohexanoler
DE60133014D1 (de)	2008-04-10	H3 agonisten oder antagonisten
DE60135471D1 (de)	2008-10-02	H3 agonisten oder antagonisten
AR028075A1 (es)	2003-04-23	Inhibidores de la peptido-desformilasa
DE60137845D1 (de)	2009-04-16	Rauscharmes spektroskopisches ellipsometer
DE60110606D1 (de)	2005-06-09	16alpha-methyl oder ethyl substituierte oestrogene
ATE491683T1 (de)	2011-01-15	Muskarine agonisten
DE60216967D1 (de)	2007-02-01	Substituierte cyclohexanderivate
SE0103291D0 (sv)	2001-10-03	New use
SE0100798D0 (sv)	2001-03-08	New use

Legal Events

Date	Code	Title	Description
2009-04-02	8364	No opposition during term of opposition