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DE60007124D1 - Aminoalkyl substituierte (benzodioxane,benzofurane oder benzopyrane) derivate - Google Patents

Aminoalkyl substituierte (benzodioxane,benzofurane oder benzopyrane) derivate

Info

Publication number
DE60007124D1
DE60007124D1 DE60007124T DE60007124T DE60007124D1 DE 60007124 D1 DE60007124 D1 DE 60007124D1 DE 60007124 T DE60007124 T DE 60007124T DE 60007124 T DE60007124 T DE 60007124T DE 60007124 D1 DE60007124 D1 DE 60007124D1
Authority
DE
Germany
Prior art keywords
benzodioxanes
benzofuranes
benzopyrans
derivatives
aminoalkyl substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60007124T
Other languages
English (en)
Other versions
DE60007124T2 (de
Inventor
Emelen Kristof Van
Bruyn Marcel Frans De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE60007124D1 publication Critical patent/DE60007124D1/de
Application granted granted Critical
Publication of DE60007124T2 publication Critical patent/DE60007124T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
DE60007124T 1999-06-02 2000-05-23 Aminoalkyl substituierte (benzodioxane,benzofurane oder benzopyrane) derivate Expired - Lifetime DE60007124T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99201747 1999-06-02
EP99201747 1999-06-02
PCT/EP2000/004746 WO2000075136A1 (en) 1999-06-02 2000-05-23 Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives

Publications (2)

Publication Number Publication Date
DE60007124D1 true DE60007124D1 (de) 2004-01-22
DE60007124T2 DE60007124T2 (de) 2004-09-23

Family

ID=8240260

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60007124T Expired - Lifetime DE60007124T2 (de) 1999-06-02 2000-05-23 Aminoalkyl substituierte (benzodioxane,benzofurane oder benzopyrane) derivate

Country Status (33)

Country Link
US (2) US6864273B1 (de)
EP (1) EP1187829B1 (de)
JP (1) JP2003501427A (de)
KR (1) KR100699512B1 (de)
CN (1) CN1150191C (de)
AR (1) AR033334A1 (de)
AT (1) ATE256125T1 (de)
AU (1) AU773773B2 (de)
BG (1) BG65269B1 (de)
BR (1) BR0011237A (de)
CA (1) CA2374902C (de)
CZ (1) CZ20014177A3 (de)
DE (1) DE60007124T2 (de)
DK (1) DK1187829T3 (de)
EA (1) EA004645B1 (de)
EE (1) EE04780B1 (de)
ES (1) ES2212774T3 (de)
HR (1) HRP20010868A2 (de)
HU (1) HUP0201404A3 (de)
IL (2) IL146840A0 (de)
MX (1) MXPA01012330A (de)
MY (1) MY120618A (de)
NO (1) NO319953B1 (de)
NZ (1) NZ514993A (de)
PL (1) PL198552B1 (de)
PT (1) PT1187829E (de)
SI (1) SI1187829T1 (de)
SK (1) SK285619B6 (de)
TR (1) TR200103430T2 (de)
TW (1) TWI289559B (de)
UA (1) UA73122C2 (de)
WO (1) WO2000075136A1 (de)
ZA (1) ZA200109860B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0201344A3 (en) 1999-06-02 2005-09-28 Janssen Pharmaceutica Nv Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives, process for their preparation and pharmaceutical compositions containing the compounds
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
KR101423284B1 (ko) * 2002-04-08 2014-07-24 제리아 신야쿠 고교 가부시키 가이샤 위 음식물 수용능 장해 치료약
EP1856126A2 (de) 2005-02-17 2007-11-21 Wyeth a Corporation of the State of Delaware Cycloalkyl-anelliertes indol, benzothiophen, benzofuran und inden-derivate
MD20140044A2 (ro) 2011-11-11 2014-08-31 Pfizer Inc. 2-Tiopirimidinone şi utilizarea lor pentru tratamentul afecţiunilor cardiovasculare
SG11201708407TA (en) 2015-05-05 2017-11-29 Pfizer 2-thiopyrimidinones

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (de) 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
WO1995005383A1 (en) 1993-08-19 1995-02-23 Janssen Pharmaceutica N.V. Vasocontrictive dihydrobenzopyran derivatives
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
HUP0201344A3 (en) 1999-06-02 2005-09-28 Janssen Pharmaceutica Nv Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives, process for their preparation and pharmaceutical compositions containing the compounds
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
EP1187829B1 (de) 2003-12-10
TR200103430T2 (tr) 2002-06-21
ES2212774T3 (es) 2004-08-01
KR20010110806A (ko) 2001-12-13
WO2000075136A1 (en) 2000-12-14
US7273862B2 (en) 2007-09-25
ZA200109860B (en) 2003-05-28
EA200101236A1 (ru) 2002-08-29
UA73122C2 (en) 2005-06-15
PL352112A1 (en) 2003-07-28
NO20015903D0 (no) 2001-12-03
CA2374902C (en) 2009-09-15
HUP0201404A3 (en) 2005-02-28
NO20015903L (no) 2001-12-03
EE04780B1 (et) 2007-02-15
EA004645B1 (ru) 2004-06-24
AU773773B2 (en) 2004-06-03
EE200100639A (et) 2003-02-17
HRP20010868A2 (en) 2003-04-30
JP2003501427A (ja) 2003-01-14
TWI289559B (en) 2007-11-11
CN1353707A (zh) 2002-06-12
SK285619B6 (sk) 2007-05-03
CA2374902A1 (en) 2000-12-14
EP1187829A1 (de) 2002-03-20
DE60007124T2 (de) 2004-09-23
MY120618A (en) 2005-11-30
KR100699512B1 (ko) 2007-03-26
ATE256125T1 (de) 2003-12-15
IL146840A (en) 2006-12-10
CN1150191C (zh) 2004-05-19
AR033334A1 (es) 2003-12-17
DK1187829T3 (da) 2004-04-13
PL198552B1 (pl) 2008-06-30
BG106156A (en) 2002-05-31
IL146840A0 (en) 2002-07-25
NO319953B1 (no) 2005-10-03
SK17032001A3 (sk) 2002-07-02
AU5525600A (en) 2000-12-28
BG65269B1 (bg) 2007-11-30
PT1187829E (pt) 2004-04-30
NZ514993A (en) 2003-05-30
US6864273B1 (en) 2005-03-08
BR0011237A (pt) 2002-03-05
SI1187829T1 (en) 2004-04-30
CZ20014177A3 (cs) 2002-05-15
MXPA01012330A (es) 2002-07-30
HUP0201404A2 (en) 2002-08-28
US20050096378A1 (en) 2005-05-05

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Legal Events

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