DE60006660D1 - Verwendung eines bestimmten hyaluronidases zur entfernung von hornhautnarbengewebe, trübung und schleier - Google Patents
Verwendung eines bestimmten hyaluronidases zur entfernung von hornhautnarbengewebe, trübung und schleierInfo
- Publication number
- DE60006660D1 DE60006660D1 DE60006660T DE60006660T DE60006660D1 DE 60006660 D1 DE60006660 D1 DE 60006660D1 DE 60006660 T DE60006660 T DE 60006660T DE 60006660 T DE60006660 T DE 60006660T DE 60006660 D1 DE60006660 D1 DE 60006660D1
- Authority
- DE
- Germany
- Prior art keywords
- corneal
- cornal
- veil
- turbidity
- removal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000134970 Cornales Species 0.000 title 1
- 108010003272 Hyaluronate lyase Proteins 0.000 title 1
- 102000001974 Hyaluronidases Human genes 0.000 title 1
- 229960002773 hyaluronidase Drugs 0.000 title 1
- 231100000241 scar Toxicity 0.000 title 1
- 102000008186 Collagen Human genes 0.000 abstract 3
- 108010035532 Collagen Proteins 0.000 abstract 3
- 229920001436 collagen Polymers 0.000 abstract 3
- 239000000835 fiber Substances 0.000 abstract 3
- 238000002306 biochemical method Methods 0.000 abstract 2
- 230000008030 elimination Effects 0.000 abstract 2
- 238000003379 elimination reaction Methods 0.000 abstract 2
- 230000004438 eyesight Effects 0.000 abstract 2
- 208000006069 Corneal Opacity Diseases 0.000 abstract 1
- 208000028006 Corneal injury Diseases 0.000 abstract 1
- 210000004087 cornea Anatomy 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 230000008736 traumatic injury Effects 0.000 abstract 1
- 230000004304 visual acuity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cereal-Derived Products (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13155899P | 1999-04-29 | 1999-04-29 | |
| US131558P | 1999-04-29 | ||
| PCT/US2000/011369 WO2000066139A2 (en) | 1999-04-29 | 2000-04-28 | Biochemical methods that eliminate corneal scars, opacification and haze |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60006660D1 true DE60006660D1 (de) | 2003-12-24 |
| DE60006660T2 DE60006660T2 (de) | 2004-09-30 |
Family
ID=22449978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60006660T Expired - Fee Related DE60006660T2 (de) | 1999-04-29 | 2000-04-28 | Verwendung eines bestimmten hyaluronidases zur entfernung von hornhautnarbengewebe, trübung und schleier |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6737075B2 (de) |
| EP (1) | EP1173198B1 (de) |
| JP (1) | JP2002543143A (de) |
| AT (1) | ATE254471T1 (de) |
| AU (1) | AU4672300A (de) |
| CA (1) | CA2370504A1 (de) |
| DE (1) | DE60006660T2 (de) |
| DK (1) | DK1173198T3 (de) |
| ES (1) | ES2209877T3 (de) |
| HK (1) | HK1045645A1 (de) |
| MX (1) | MXPA01011025A (de) |
| PT (1) | PT1173198E (de) |
| WO (1) | WO2000066139A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7061237B2 (en) * | 2000-07-13 | 2006-06-13 | The Regents Of The University Of California | Remote NMR/MRI detection of laser polarized gases |
| ES2325681T3 (es) | 2000-10-13 | 2009-09-14 | The Johns Hopkins University | Activador de plasminogeno para prevenir turbidez corneal y subepitelial despues de cirugia de correccion de la vision con laser. |
| US6902548B1 (en) * | 2001-03-19 | 2005-06-07 | Ed Schuler | Use of Streptomyces hyalurolyticus enzyme in ophthalmic treatments |
| US7156859B2 (en) | 2001-07-23 | 2007-01-02 | Fos Holding S.A. | Device for separating the epithelium layer from the surface of the cornea of an eye |
| JP3921375B2 (ja) * | 2001-10-12 | 2007-05-30 | 株式会社ニデック | 眼科装置及び角膜手術装置 |
| GB2389123B (en) | 2002-05-29 | 2005-08-17 | Unilever Plc | Rechargeable dispensing device |
| SG177008A1 (en) | 2003-03-05 | 2012-01-30 | Halozyme Inc | Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof |
| US7703919B2 (en) * | 2003-03-28 | 2010-04-27 | Digital Vision, Llc | Application of neuro-ocular wavefront data in vision correction |
| JP2007503902A (ja) * | 2003-09-05 | 2007-03-01 | サイトレイト ビー.ブイ. | 角膜上皮の分離装置 |
| MXPA03011987A (es) | 2003-12-19 | 2005-06-23 | Osio Sancho Alberto | Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal. |
| AU2006201459B2 (en) * | 2005-04-08 | 2012-08-09 | Theodore Coroneo Minas | Corneal shaping |
| EP2004209B1 (de) * | 2006-04-13 | 2013-07-24 | Euclid Systems Corporation | Zusammensetzung und verfahren zur stabilisierung des hornhautgewebes nach einem refraktiven chirurgischen eingriff |
| JP4871024B2 (ja) * | 2006-05-26 | 2012-02-08 | スター・ジャパン株式会社 | 眼内挿入用レンズの挿入器具 |
| TWI395593B (zh) | 2008-03-06 | 2013-05-11 | Halozyme Inc | 可活化的基質降解酵素之活體內暫時性控制 |
| KR102114111B1 (ko) | 2012-08-10 | 2020-05-25 | 오시오 코포레이션 디/비/에이 율리아 헬스 | 안과적 상태 치료시의 컨택트 렌즈 사용 |
| WO2015073397A1 (en) | 2013-11-13 | 2015-05-21 | Thixos Llc | Devices, kits and methods relating to treatment of facet joints |
| CN105079809A (zh) * | 2015-07-09 | 2015-11-25 | 广州赛莱拉干细胞科技股份有限公司 | 组合物、制剂、制剂的制备方法、应用及使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4174389A (en) * | 1977-05-13 | 1979-11-13 | Cope Louise A | Ophthalmic use of collagenase |
| US5270051A (en) * | 1991-10-15 | 1993-12-14 | Harris Donald H | Enzyme-orthokeratology |
| US5788957A (en) * | 1991-10-15 | 1998-08-04 | Advanced Corneal Systems, Inc. | Enzyme-orthokeratology |
| DE4214215A1 (de) * | 1992-04-30 | 1993-11-04 | Behringwerke Ag | Verwendung von inhibitoren von plasminogenaktivatoren zur behandlung von entzuendungen |
| US5866120A (en) * | 1995-11-22 | 1999-02-02 | Advanced Corneal Systems, Inc. | Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase |
| DK0983084T3 (da) * | 1997-05-22 | 2007-05-07 | Ista Pharmaceuticals Inc | Anvendelse af hyaluronidase til fremstilling af et öjenpræparat til flydendegörelse af glaslegemet i behandlingen af öjenlidelser |
-
2000
- 2000-04-28 DE DE60006660T patent/DE60006660T2/de not_active Expired - Fee Related
- 2000-04-28 MX MXPA01011025A patent/MXPA01011025A/es active IP Right Grant
- 2000-04-28 DK DK00928486T patent/DK1173198T3/da active
- 2000-04-28 AU AU46723/00A patent/AU4672300A/en not_active Abandoned
- 2000-04-28 CA CA002370504A patent/CA2370504A1/en not_active Abandoned
- 2000-04-28 JP JP2000615023A patent/JP2002543143A/ja not_active Withdrawn
- 2000-04-28 WO PCT/US2000/011369 patent/WO2000066139A2/en not_active Ceased
- 2000-04-28 AT AT00928486T patent/ATE254471T1/de not_active IP Right Cessation
- 2000-04-28 HK HK02105457.3A patent/HK1045645A1/zh unknown
- 2000-04-28 ES ES00928486T patent/ES2209877T3/es not_active Expired - Lifetime
- 2000-04-28 EP EP00928486A patent/EP1173198B1/de not_active Expired - Lifetime
- 2000-04-28 PT PT00928486T patent/PT1173198E/pt unknown
-
2001
- 2001-10-10 US US09/975,039 patent/US6737075B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE254471T1 (de) | 2003-12-15 |
| DE60006660T2 (de) | 2004-09-30 |
| WO2000066139A2 (en) | 2000-11-09 |
| US20020119141A1 (en) | 2002-08-29 |
| WO2000066139A3 (en) | 2001-03-08 |
| JP2002543143A (ja) | 2002-12-17 |
| EP1173198B1 (de) | 2003-11-19 |
| AU4672300A (en) | 2000-11-17 |
| ES2209877T3 (es) | 2004-07-01 |
| EP1173198A2 (de) | 2002-01-23 |
| MXPA01011025A (es) | 2002-11-07 |
| CA2370504A1 (en) | 2000-11-09 |
| US6737075B2 (en) | 2004-05-18 |
| DK1173198T3 (da) | 2004-04-13 |
| HK1045645A1 (zh) | 2002-12-06 |
| PT1173198E (pt) | 2004-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |