[go: up one dir, main page]

DE237507T1 - Vorrichtung zur inhalation von pulver. - Google Patents

Vorrichtung zur inhalation von pulver.

Info

Publication number
DE237507T1
DE237507T1 DE198787850060T DE87850060T DE237507T1 DE 237507 T1 DE237507 T1 DE 237507T1 DE 198787850060 T DE198787850060 T DE 198787850060T DE 87850060 T DE87850060 T DE 87850060T DE 237507 T1 DE237507 T1 DE 237507T1
Authority
DE
Germany
Prior art keywords
unit
air
inhalation
nozzle
nozzle unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198787850060T
Other languages
English (en)
Inventor
Jan Anders Roland S-240 17 S Sandby Andersson
Risto Sf-01900 Nurmijaervi Virtanen
Kjell Ingvat Leopold S-240 17 S Sandby Wetterlin
Original Assignee
Aktiebolaget Draco, Lund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26659278&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE237507(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aktiebolaget Draco, Lund filed Critical Aktiebolaget Draco, Lund
Publication of DE237507T1 publication Critical patent/DE237507T1/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/002Particle size control by flow deviation causing inertial separation of transported particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Nozzles (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Inorganic Insulating Materials (AREA)
  • External Artificial Organs (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Disintegrating Or Milling (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Cyclones (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Gyroscopes (AREA)
  • Amplifiers (AREA)

Claims (13)

850 060.2 Aktiebolaget Draco Patentansprüche
1. Vorrichtung in Pulverinhalationseinrichtungen zum Inhalieren eines Luftstromes, der eine pharmakologisch aktive Verbindung in atomisierter oder mikronisierter Form enthält und der eine Düseneinheit (2) aufweist mit einer Düsenöffnung (2a) sowie eine Behältereinheit (3) mit einer Freigabe- oder Dosiereinheit (6) zur Abgabe der aktiven Verbindung, wobei der durch die Inhalation erzeugte Luftstrom mindestens teilweise durch eine Luftleitung (7) in der Behältereinheit (3) angesaugt wird und die Leitung, die sich von einem Lufteinlaß (8) erstreckt, mit der Umgebung in Verbindung steht über die Freigabe- oder Dosiereinheit (6) bis zu der Düseneinheit (2) hin, gekennzeichnet durch stationär in dem Behälter (3) und/oder der Duseneinheit (2) angeordnete Ablenkvorrichtungen (13, 15, 16), die sich in wesentlichem Ausmaß zum Zentrum der Vorrichtungen erstrecken und so angeordnet sind, daß sie der durch Inhalation erzeugten Luftströmung eine kräftige Ablenkbewegung erteilen.
2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß
die Ablenkvorrichtungen (13, 15, 16) derart angeordnet sind, daß sie der durch Inhalation erzeugten Luftströmung eine Drehbewegung erteilen.
3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, daß
längs der Mittelachse der Ablenkvorrichtungen (13, 15, 16) zur Verringerung des Fließwiderstandes ein durchgehendes Loch angeordnet ist.
4. Vorrichtung nach Anspruch 3, dadurch gekennzeichnet, daß
das Verhältnis der radialen Erstreckung des Loches zu der der Ablenkvorrichtungen 0 - 50 % ist.
5. Vorrichtung nach Anspruch 1 oder 2, bei welcher mindestens ein zusätzlicher Lufteinlaß (14, 14') in dem Behälter (3) oder der Düseneinheit (2) angeordnet ist für das Einsaugen von Verdünnungsluft in den durch Inhalation erzeugten Luftstrom zwischen der Dosiereinheit (6) und der Düsenöffnung (2a), dadurch gekennzeichnet, daß die Ablenkvorrichtungen (15, 16) derart angeordnet sind, daß sie den Verdünnungsluftstrom und/oder den mit Partikeln gesättigten Luftstrom im Bereich der Luftleitung (7) kräftig ablenken.
6. Vorrichtung nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, daß die Ablenkvorrichtungen mindestens einen im wesentlichen schraubenförmig gebildeten Kanalteil (13, 15, 16) aufweisen.
7. Vorrichtung nach Anspruch 6, dadurch gekennzeichnet, daß mindestens ein schraubenförmiger Kanalteil (13), der mit der Düsenöffnung (2a) verbunden ist, in der Düseneinheit
(2) angeordnet ist.
8. Vorrichtung nach Anspruch 7, dadurch gekennzeichnet, daß die Düseneinheit (2) zur Düsenöffnung (2a) hin mit einer kontinuierlich abnehmenden Querschnittsfläche ausgestal-
tet ist. . .
9. Vorrichtung nach Anspruch 6 oder 7, dadurch gekennzeichnet, daß mindestens ein mit der Düseneinheit (2) verbundener schraubenförmiger Kanalteil im Bereich der Luftlei-
OQ tung (7) angeordnet ist.
10. Vorrichtung nach Anspruch 7 oder 8, dadurch gekennzeichnet, daß mindestens der Teil der Düseneinheit (2) neben der Behältereinheit (3) aus einer freien, inneren Kammer
(9) besteht, durch welche die durch Inhalation erzeugte Luftströmung hindurchgeht.
11. Vorrichtung nach einem der vorhergehenden Ansprüche in
Kombination mit Anspruch 5, bei welcher der zusätzliche Lufteinlaß (141) in der Behältereinheit (3) angeordnet ist und dadurch gekennzeichnet ist, daß der zusätzliche Lufteinlaß (141) mit einem getrennten, schraubenförmigen Kanalteil (16) verbunden ist, welches in der Luftleitung (7) oder der .Düseneinheit (2) endet.
12. Vorrichtung nach Anspruch 10, dadurch gekennzeichnet, daß der separate, schraubenförmige Kanalteil (16) in einer Hülloberfläche angeordnet ist, welche die Luftleitung (7) umgibt.
13. Pulverinhalationseinrichtung nach einem der Ansprüche 6 bis 11, dadurch gekennzeichnet, daß die Querschnittsfläehe des jeweiligen schraubenförmigen Kanalteils (13, 15, 16) 5-50 mm2 beträgt und daß die Gesamtlänge der schraubenförmigen Kanalteile 5 - 50 mm beträgt.
DE198787850060T 1986-03-07 1987-02-20 Vorrichtung zur inhalation von pulver. Pending DE237507T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8601060A SE453566B (sv) 1986-03-07 1986-03-07 Anordning vid pulverinhalatorer
SG92094A SG92094G (en) 1986-03-07 1994-07-11 Device in powder inhalators

Publications (1)

Publication Number Publication Date
DE237507T1 true DE237507T1 (de) 1988-05-19

Family

ID=26659278

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198787850060T Pending DE237507T1 (de) 1986-03-07 1987-02-20 Vorrichtung zur inhalation von pulver.
DE8787850060T Expired - Lifetime DE3775433D1 (de) 1986-03-07 1987-02-20 Vorrichtung zur inhalation von pulver.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8787850060T Expired - Lifetime DE3775433D1 (de) 1986-03-07 1987-02-20 Vorrichtung zur inhalation von pulver.

Country Status (31)

Country Link
US (1) US4907583A (de)
EP (1) EP0237507B1 (de)
JP (1) JPH0824715B2 (de)
KR (1) KR960007754B1 (de)
AT (1) ATE70720T1 (de)
AU (1) AU601400B2 (de)
CA (1) CA1276848C (de)
CY (1) CY1798A (de)
DE (2) DE237507T1 (de)
DK (1) DK162424C (de)
EG (1) EG18100A (de)
ES (1) ES2000997T3 (de)
FI (1) FI88679C (de)
GR (2) GR880300028T1 (de)
HK (1) HK80194A (de)
HR (1) HRP920761B1 (de)
HU (1) HU202763B (de)
IE (1) IE60112B1 (de)
IL (1) IL81686A (de)
IN (1) IN168166B (de)
IS (1) IS1390B6 (de)
NO (1) NO164001C (de)
NZ (1) NZ219445A (de)
PH (1) PH25194A (de)
PL (1) PL149599B1 (de)
PT (1) PT84421B (de)
SE (1) SE453566B (de)
SG (1) SG92094G (de)
SI (1) SI8710341B (de)
YU (1) YU46977B (de)
ZA (1) ZA871346B (de)

Families Citing this family (274)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI84698C (fi) * 1989-06-16 1992-01-10 Huhtamaeki Oy Anordning foer finfoerdelning av agglomerat av en enkeldos av ett laekemedelpreparat i pulverform.
SE9002895D0 (sv) * 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
UA26915C2 (uk) * 1990-09-12 1999-12-29 Ханс БІСГОРД Іhгаляторhий пристрій для вдихаhhя активhої порошкоподібhої або рідкої речовиhи
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
AU654979B2 (en) * 1990-10-05 1994-12-01 University Of North Carolina At Chapel Hill, The Method of administering amiloride
US5304125A (en) * 1990-10-05 1994-04-19 The University Of North Carolina Apparatus for administering solid particulate aerosols to the lungs
DE59107894D1 (de) * 1991-03-21 1996-07-11 Ritzau Pari Werk Gmbh Paul Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
US5797391A (en) * 1991-03-28 1998-08-25 Rhone-Poulenc Rorer Limited Inhaler
DK0533683T3 (da) * 1991-04-15 1997-01-13 Leiras Oy Indretning til måling af en dosis pulveriseret medikament til inhalering
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
ES2141108T3 (es) * 1991-07-02 2000-03-16 Inhale Inc Metodo y dispositivo para proporcionar medicamentos en aerosol.
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
US5469843A (en) * 1991-11-12 1995-11-28 Minnesota Mining And Manufacturing Company Inhalation device
GB9123953D0 (en) * 1991-11-12 1992-01-02 Minnesota Mining & Mfg Inhalation device
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
ES2179831T3 (es) * 1992-09-29 2003-02-01 Inhale Therapeutic Syst Liberacion en los pulmones de fragmentos activos de hormona paratiroidiana.
DE4237568C1 (de) * 1992-11-06 1994-05-11 Dieter Dipl Ing Dr Med Koehler Verfahren und Vorrichtung zum Erzeugen eines Aerosols
DE4239402A1 (de) * 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US6250300B1 (en) 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
WO1994014492A2 (en) * 1992-12-18 1994-07-07 Schering Corporation Inhaler for powdered medications
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
EP0691864A4 (de) * 1993-03-03 1996-07-03 Tenax Corp Medikamententräger für trockenpuverinhalator
GB9306703D0 (en) * 1993-03-31 1993-05-26 Fisons Plc Inhalation device
DE69413528T2 (de) * 1993-04-06 1999-05-06 Minnesota Mining And Mfg. Co., Saint Paul, Minn. Vorrichtung zum deagglomerieren für trockenpulverinhalatoren
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
TW402506B (en) 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
WO1995012428A1 (de) * 1993-10-30 1995-05-11 Koehler Dieter Verfahren und vorrichtung zum erzeugen eines aerosols aus einer pulverförmigen substanz
DE4340768A1 (de) * 1993-11-30 1995-06-01 Bayer Ag Vorrichtung zum Inhalieren
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
GB9326574D0 (en) * 1993-12-31 1994-03-02 King S College London Dry power inhalers
DE4400084C2 (de) * 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
WO1995024183A1 (en) * 1994-03-07 1995-09-14 Inhale Therapeutic Systems Methods and compositions for pulmonary delivery of insulin
AU124387S (en) * 1994-03-25 1995-08-11 Astra Ab Training device for an inhaler
EP0759939B1 (de) * 1994-05-18 2005-07-20 Nektar Therapeutics Methoden und zusammensetzungen für die trockenpuderarznei aus interferonen
US6165976A (en) 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
JP3706136B2 (ja) 1994-09-21 2005-10-12 ネクター セラピューティクス 乾燥粉末薬剤の分散装置及び方法
DE4440734A1 (de) * 1994-11-15 1996-05-23 Bayer Ag Abscheidesystem für einen Pulverinhalator
SE9404439D0 (sv) * 1994-12-21 1994-12-21 Astra Ab Inhalation device
ATE236617T1 (de) 1994-12-22 2003-04-15 Astrazeneca Ab Aerosol-arzneiformulierungen
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
CZ182297A3 (cs) * 1994-12-22 1998-01-14 Astra Aktiebolag Terapeutický přípravek pro inhalaci obsahující parathyroidní hormon, PTH
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
SE9502799D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Device in inhalers
SE9502800D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Disposable inhaler
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US6182655B1 (en) 1995-12-07 2001-02-06 Jago Research Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
ATE209939T1 (de) * 1996-01-03 2001-12-15 Glaxo Group Ltd Inhalator
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
RU2195965C2 (ru) * 1996-02-21 2003-01-10 Шеринг Корпорейшн Устройство для ингаляции порошка
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
GB9626263D0 (en) 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
SE9700424D0 (sv) 1997-02-07 1997-02-07 Astra Ab Powder inhaler
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700938D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler II and a method of construction thereof
SE9700937D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
SE9700940D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler IV
SE9700943D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler V
SE9700948D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler X
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
SE9700944D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler VI
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US6237590B1 (en) 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
US6345617B1 (en) * 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
WO1999033505A1 (en) * 1997-12-23 1999-07-08 Euro-Celtique S.A. Particle separator for an inhaler
US7143764B1 (en) 1998-03-13 2006-12-05 Astrazeneca Ab Inhalation device
AP1342A (en) 1998-03-16 2004-12-15 Nektar Therapeutics Aerosolized active agent delivery.
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
SE9801122D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB9905538D0 (en) 1999-03-10 1999-05-05 Glaxo Group Ltd A device
AU777278B2 (en) 1999-06-05 2004-10-07 Innovata Biomed Limited Delivery system
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
ES2569916T3 (es) 1999-06-29 2016-05-13 Mannkind Corporation Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
AU2374901A (en) * 1999-12-07 2001-06-18 Orion Corporation Multidose powder inhaler
ES2257996T3 (es) 2000-04-07 2006-08-16 Andi-Ventis Limited Boquilla para inhalador de particulas.
CA2406185C (en) 2000-04-11 2011-03-15 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
US8404217B2 (en) * 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
TWI290473B (en) 2000-05-10 2007-12-01 Alliance Pharma Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US20020106368A1 (en) * 2000-07-28 2002-08-08 Adrian Bot Novel methods and compositions to upregulate, redirect or limit immune responses to peptides, proteins and other bioactive compounds and vectors expressing the same
US6902734B2 (en) 2000-08-07 2005-06-07 Centocor, Inc. Anti-IL-12 antibodies and compositions thereof
UA81743C2 (uk) 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
US7288390B2 (en) 2000-08-07 2007-10-30 Centocor, Inc. Anti-dual integrin antibodies, compositions, methods and uses
CA2422941A1 (en) * 2000-09-20 2003-03-19 Franco Del Bon Inhalator and pertaining atomizer
US6595210B2 (en) * 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
ATE369121T1 (de) * 2001-02-06 2007-08-15 Innovata Biomed Ltd Bimodale trockenpulverzusammensetzung zur inhalation
US8337816B2 (en) 2001-09-17 2012-12-25 Glaxo Group Limited Dry powder medicament formulations
ES2624547T3 (es) 2001-11-14 2017-07-14 Janssen Biotech, Inc. Anticuerpos anti il 6, composiciones, métodos y usos
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
AU2002251610A1 (en) * 2001-12-25 2003-07-15 Evgeny Viktorovich Babarskov Device for inhaling powder-like medicinal agents
US6929798B2 (en) 2002-02-13 2005-08-16 Immunology Laboratories, Inc. Compositions and methods for treatment of microbial infections
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
CA2490409A1 (en) 2002-06-28 2004-01-08 Centocor, Inc. Mammalian ch1 deleted mimetibodies, compositions, methods and uses
ES2278170T3 (es) 2002-07-09 2007-08-01 BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG Composiciones farmaceuticas de anticolinergicos e inhibidores de la quinasa p38 en el tratamiento de enfermedades respiratorias.
DK1658872T4 (da) 2002-07-31 2019-11-11 Chiesi Farm Spa Pulverinhalator
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
EP1488819A1 (de) * 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Trockenpulverinhalator und Verfahren zur pulmonalen Inhalation von Trockenpulver
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
KR20060052911A (ko) 2003-07-29 2006-05-19 베링거 인겔하임 인터내셔날 게엠베하 베타흥분제와 항콜린제를 포함하는 흡입용 의약품
UA89481C2 (uk) 2003-09-30 2010-02-10 Центокор, Инк. Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування
WO2005040163A1 (en) 2003-10-28 2005-05-06 Dr. Reddy's Laboratories Ltd Heterocyclic compounds that block the effects of advanced glycation end products (age)
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
RU2258539C1 (ru) * 2004-03-23 2005-08-20 Чучалин Александр Григорьевич Порошковый ингалятор
WO2005097175A2 (en) 2004-03-31 2005-10-20 Centocor, Inc. Human glp-1 mimetibodies, compositions, methods and uses
JP2007533387A (ja) * 2004-04-21 2007-11-22 イノベータ バイオメド リミテッド 吸入器
NZ550797A (en) 2004-04-22 2010-08-27 Boehringer Ingelheim Int Pharmaceutical combinations containing 6-hydroxy-8-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1,1-dimethylethylamino]-ethyl}-4H-benzo[1,4]oxazin-3-one for treating respiratory diseases
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7727962B2 (en) 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7611709B2 (en) 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
UY28908A1 (es) * 2004-05-19 2005-12-30 Cipla Ltd Dispositivo inhalador de medicamentos
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
ES2385934T3 (es) 2004-08-20 2012-08-03 Mannkind Corporation Catálisis de la síntesis de dicetopiperazina.
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
US7393662B2 (en) 2004-09-03 2008-07-01 Centocor, Inc. Human EPO mimetic hinge core mimetibodies, compositions, methods and uses
WO2006031775A2 (en) * 2004-09-13 2006-03-23 Oriel Therapeutics, Inc. Dry powder inhalers that inhibit agglomeration, related devices and methods
PA8672101A1 (es) 2005-04-29 2006-12-07 Centocor Inc Anticuerpos anti-il-6, composiciones, métodos y usos
EP1898894A1 (de) * 2005-06-17 2008-03-19 Boehringer Ingelheim International GmbH Mrp-iv-hemmer zur behandlung von atemwegserkrankungen
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
EP1896073B1 (de) 2005-06-30 2013-03-06 Janssen Biotech, Inc. Anti-il-23-antikörper, zusammensetzungen, verfahren und verwendung
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
EP1901793A1 (de) * 2005-07-13 2008-03-26 Cipla Ltd. Inhalator
DK1917253T3 (da) 2005-08-15 2015-03-30 Boehringer Ingelheim Int Fremgangsmåde til fremstilling af betamimetika
US7799344B2 (en) 2005-09-14 2010-09-21 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
TWI396541B (zh) 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
PT2548577T (pt) 2005-12-29 2017-05-29 Janssen Biotech Inc Anticorpos humanos anti-il-23, composições, métodos e usos
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
US8039431B2 (en) 2006-02-22 2011-10-18 Mannkind Corporation Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
CN101437562A (zh) * 2006-03-03 2009-05-20 Stc.Unm公司 具有气动力弹性分散机构的干粉吸入器
US8127763B2 (en) * 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
US7718609B2 (en) 2006-04-12 2010-05-18 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2008014543A1 (en) 2006-08-04 2008-02-07 Resmed Ltd Nasal prongs for mask system
EP2051714B1 (de) 2006-08-07 2011-04-13 Boehringer Ingelheim International GmbH Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
ES2766770T3 (es) 2006-08-10 2020-06-15 Roy C Levitt Anakinra para uso en el tratamiento del síndrome de bronquiolitis obliterante
UY30550A1 (es) 2006-08-22 2008-03-31 Boehringer Ingelheim Int Nuevos beta-agonistas enantioméricamente puros, procedimientos para su preparacion y su uso como medicamentos
DE102006047667B3 (de) * 2006-09-28 2008-04-24 Ing. Erich Pfeiffer Gmbh Inhalationsvorrichtung
TW200843794A (en) 2006-12-21 2008-11-16 Centocor Inc Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles
WO2009046215A2 (en) * 2007-10-02 2009-04-09 Lab International Srl Safety and abuse deterrent improved device
CA2709071C (en) 2007-12-14 2016-11-15 Labogroup S.A.S. Delivering aerosolizable food products
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
MX371521B (es) * 2008-03-27 2020-01-31 Mannkind Corp Sistema de inhalacion de polvo seco.
WO2009149478A1 (de) * 2008-06-12 2009-12-17 Rouven Haas Vorrichtung zur zuführung von partikel-material in den mund
US8485180B2 (en) * 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2293833T3 (en) * 2008-06-13 2016-05-23 Mannkind Corp DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
WO2010008523A1 (en) 2008-07-13 2010-01-21 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8563697B2 (en) 2008-08-14 2013-10-22 Cephalon Australia Pty. Ltd. Anti-IL-12/IL-23 antibodies
WO2010051274A2 (en) 2008-10-31 2010-05-06 Centocor Ortho Biotech Inc. Fibronectin type iii domain based scaffold compositions, methods and uses
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2393492A1 (de) 2009-02-09 2011-12-14 Boehringer Ingelheim International GmbH Neue pharmazeutische zusammensetzungen zur behandlung von atemwegs- und gastrointestinalen erkrankungen
BRPI1008532B1 (pt) 2009-02-12 2021-12-14 Janssen Biotech, Inc Arcabouço de proteína isolada, método para construção de uma biblioteca de arcabouço de proteína isolada, molécula de ácido nucleico isolada, vetor de ácido nucleico isolado, célula hospedeira de bactéria ou fungo, composição, dispositivo médico e artigo de manufatura para uso farmacêutico ou de diagnóstico em seres humanos
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
CA2756412C (en) 2009-03-25 2019-02-26 The Board Of Regents Of The University Of Texas System Compositions for stimulation of mammalian innate immune resistance to pathogens
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
WO2011005645A1 (en) 2009-07-06 2011-01-13 Boehringer Ingelheim International Gmbh Polymorph of [4,6-bis(dimethylamino)-2-(4-{[4-(trifluoromethyl)benzoyl]amino}benzyl)pyrimidin-5-yl]
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
US9492625B2 (en) 2009-11-12 2016-11-15 Stc.Unm Dry powder inhaler with flutter dispersion member
EP2504318A2 (de) 2009-11-24 2012-10-03 Boehringer Ingelheim International GmbH Kristalline salzformen eines pyrimidin-5-yl-essigsäurederivats
CA2781610A1 (en) 2009-11-24 2011-06-03 Boehringer Ingelheim International Gmbh Process for preparing a polymorph of the choline salt of a pyrimidin-5-yl acetic acid derivative
KR20130009760A (ko) 2010-02-10 2013-01-23 이뮤노젠 아이엔씨 Cd20 항체 및 이의 용도
CA2801210C (en) 2010-06-19 2020-07-21 Memorial Sloan-Kettering Cancer Center Anti-gd2 antibodies
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
CN101856531A (zh) * 2010-06-22 2010-10-13 于清 用于药物输送的高效干粉吸入器及其药物输送方法
EP2648788B1 (de) 2010-12-07 2017-08-09 Respira Therapeutics, Inc. Trockenpulverinhalator
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2012175735A1 (en) 2011-06-23 2012-12-27 Vib Vzw A20 inhibitors for the treatment of respiratory viral infections
EP2776053A1 (de) 2011-10-24 2014-09-17 MannKind Corporation Verfahren und zusammensetzungen zur schmerzbehandlung
JP5840457B2 (ja) * 2011-10-31 2016-01-06 株式会社吉野工業所 点鼻薬噴出器
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
TWI718086B (zh) 2013-01-07 2021-02-11 英屬維爾京群島商遠東超級實驗室有限公司 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物
US9492646B2 (en) 2013-03-06 2016-11-15 Nordson Corporation Applicator and method for dispensing a fluid and a particulate
CA2903576C (en) 2013-03-15 2021-06-08 Nai-Kong V. Cheung High affinity anti-gd2 antibodies
AU2014228415B2 (en) 2013-03-15 2018-08-09 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX394255B (es) 2013-07-18 2025-03-24 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos
EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
KR102111922B1 (ko) * 2013-08-08 2020-05-19 엠이디 2000 에스.알.엘. 에어로졸 요법용 분무기 약병
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
SE539930C2 (sv) * 2014-04-03 2018-01-23 Iconovo Ab Torrpulverinhalator
SE538400C2 (sv) * 2014-04-03 2016-06-14 Iconovo Ab Torrpulverinhalator
WO2018140026A1 (en) 2017-01-27 2018-08-02 Memorial Sloan Kettering Cancer Center Bispecific her2 and cd3 binding molecules
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3244952A4 (de) 2015-01-14 2018-11-14 Respira Therapeutics, Inc. Pulverdispersionsverfahren und -vorrichtungen
CN107667120B (zh) 2015-03-17 2022-03-08 纪念斯隆-凯特林癌症中心 抗muc16抗体及其应用
US11000652B2 (en) 2015-05-08 2021-05-11 Iconovo Ab Dry powder inhaler
AU2017296236A1 (en) 2016-07-15 2019-01-03 Poseida Therapeutics, Inc. Chimeric antigen receptors and methods for use
CA3027247A1 (en) 2016-07-15 2018-01-18 Poseida Therapeutics, Inc. Chimeric antigen receptors (cars) specific for muc1 and methods for their use
KR102515202B1 (ko) 2016-11-09 2023-03-29 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 후천성 면역 조절을 위한 방법 및 조성물
AU2017369977A1 (en) * 2016-11-30 2019-04-11 Philip Morris Products S.A. Inhaler with swirl end plug
WO2018112037A1 (en) 2016-12-16 2018-06-21 Jia Zhou Inhibitors of bromodomain-containing protein 4 (brd4)
CN110234351A (zh) 2017-01-30 2019-09-13 詹森生物科技公司 用于治疗活动性银屑病关节炎的抗tnf抗体、组合物和方法
CA3052578A1 (en) 2017-02-07 2018-08-16 Janssen Biotech, Inc. Anti-tnf antibodies, compositions, and methods for the treatment of active ankylosing spondylitis
EP3687608B1 (de) 2017-09-28 2025-06-18 Iconovo AB Trockenpulverinhalator mit mitteln zur verbesserung der dispersion
US12415844B2 (en) 2017-12-20 2025-09-16 Poseida Therapeutics, Inc. BCMA specific VCAR compositions and methods for use
EP3746123A4 (de) 2018-02-01 2021-12-01 Memorial Sloan-Kettering Cancer Center Antikörper gegen galectin-3 und verfahren zur verwendung davon
US20190345245A1 (en) 2018-05-11 2019-11-14 Janssen Biotech, Inc. Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
US11389433B2 (en) 2018-06-18 2022-07-19 Board Of Regents, The University Of Texas System BRD4 inhibitor treatment of IgE-mediated diseases
JP7689074B2 (ja) 2019-01-15 2025-06-05 ヤンセン バイオテツク,インコーポレーテツド 若年性特発性関節炎の治療のための抗tnf抗体、組成物、及び方法
KR20210118878A (ko) 2019-01-23 2021-10-01 얀센 바이오테크 인코포레이티드 건선성 관절염의 치료 방법에 사용하기 위한 항-tnf 항체 조성물
EP3924023A1 (de) 2019-02-15 2021-12-22 Iconovo AB Inhalator
MA55282A (fr) 2019-03-14 2022-01-19 Janssen Biotech Inc Procédés de fabrication pour la production de compositions d'anticorps anti-tnf
EA202192508A1 (ru) 2019-03-14 2022-03-29 Янссен Байотек, Инк. Способы получения композиций антитела к фно
JP7635137B2 (ja) 2019-03-14 2025-02-25 ヤンセン バイオテツク,インコーポレーテツド 抗tnf抗体組成物を産生するための方法
JP7805788B2 (ja) 2019-05-23 2026-01-26 ヤンセン バイオテツク,インコーポレーテツド Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
CN114173873A (zh) 2019-06-03 2022-03-11 詹森生物科技公司 用于治疗活动性强直性脊柱炎的抗tnf抗体、组合物和方法
JP2022536279A (ja) 2019-06-03 2022-08-15 ヤンセン バイオテツク,インコーポレーテツド 乾癬性関節炎を治療するための抗tnf抗体組成物及び方法
WO2021028752A1 (en) 2019-08-15 2021-02-18 Janssen Biotech, Inc. Anti-tfn antibodies for treating type i diabetes
MX2022012956A (es) 2020-04-14 2023-03-27 Poseida Therapeutics Inc Composiciones y métodos para su uso en el tratamiento del cáncer.
WO2021214587A1 (en) 2020-04-21 2021-10-28 Janssen Biotech, Inc. Anti-tnf alpha agent for treating viral infections
WO2021214588A1 (en) 2020-04-21 2021-10-28 Janssen Biotech, Inc. Anti-tnf alpha agent for treating coronavirus infections
MX2022014430A (es) 2020-05-21 2023-02-22 Janssen Biotech Inc Método para tratar la enfermedad inflamatoria del intestino con una terapia de combinación de anticuerpos para il-23 y tnf alfa.
US20250268848A1 (en) 2021-07-02 2025-08-28 Henry Ford Health System Compositions comprising endosidin 2 for reducing sars-cov-2 infection
EP4367136A1 (de) 2021-07-09 2024-05-15 Janssen Biotech, Inc. Herstellungsverfahren zur herstellung von anti-tnf-antikörperzusammensetzungen
AU2022308201A1 (en) 2021-07-09 2024-02-22 Janssen Biotech, Inc. Manufacturing methods for producing anti-tnf antibody compositions
CN113413517A (zh) * 2021-07-28 2021-09-21 常州市第二人民医院 用于麻醉科的浓度调节式麻醉装置
US12502490B2 (en) 2022-04-29 2025-12-23 Merxin Ltd Manifold
GB2618145A (en) * 2022-04-29 2023-11-01 Merxin Ltd Manifold

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1309597A (en) * 1919-07-08 parker
US1431177A (en) * 1919-06-06 1922-10-10 Palmer Richard Inhaling device
GB682069A (en) * 1949-04-14 1952-11-05 Airmed Ltd Improvements in and relating to controlling the supply of vapours of volatile liquids
US2604094A (en) * 1949-06-25 1952-07-22 Schenley Ind Inc Inhaler
US2804341A (en) * 1956-04-13 1957-08-27 Bete Fog Nozzle Inc Spray nozzles
US4014470A (en) * 1976-03-01 1977-03-29 Bete Fog Nozzle, Inc. Conical spray nozzle
US4147166A (en) * 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
NL8020393A (de) * 1979-10-30 1981-09-01 Riker Laboratories, Inc. Te Loughborough, Groot-Brittannie.
BR8007911A (pt) * 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
DE3043377A1 (de) * 1980-11-17 1982-07-01 Brugger, Inge, 8130 Starnberg Zerstaeuber
ATE23272T1 (de) 1981-07-08 1986-11-15 Draco Ab Pulverinhalator.
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
GB2152819B (en) * 1983-12-08 1988-05-11 Anthony John Dyson Improved nebuliser

Also Published As

Publication number Publication date
HRP920761A2 (en) 1995-04-30
EG18100A (en) 1993-06-30
ES2000997T3 (es) 1992-06-16
HUT50639A (en) 1990-03-28
DK115487D0 (da) 1987-03-06
HRP920761B1 (en) 1998-10-31
PT84421B (pt) 1989-10-04
GR880300028T1 (en) 1988-10-18
SI8710341B (sl) 1998-06-30
IL81686A0 (en) 1987-09-16
EP0237507A1 (de) 1987-09-16
SG92094G (en) 1995-03-17
CY1798A (en) 1995-02-17
IE60112B1 (en) 1994-06-01
JPH0824715B2 (ja) 1996-03-13
YU34187A (en) 1989-04-30
IS1390B6 (is) 1989-09-28
AU601400B2 (en) 1990-09-13
FI871000A0 (fi) 1987-03-06
PT84421A (en) 1987-04-01
PH25194A (en) 1991-03-27
ZA871346B (de) 1987-09-07
FI88679C (fi) 1993-06-28
DK162424B (da) 1991-10-28
DK115487A (da) 1987-09-08
IS3196A7 (is) 1987-09-08
DK162424C (da) 1992-03-23
NO870938D0 (no) 1987-03-06
DE3775433D1 (de) 1992-02-06
FI88679B (fi) 1993-03-15
GR3003451T3 (en) 1993-02-17
HK80194A (en) 1994-08-19
NO164001C (no) 1990-08-22
AU6960487A (en) 1987-09-10
IE870529L (en) 1987-09-07
NO870938L (no) 1987-09-08
KR870008592A (ko) 1987-10-19
YU46977B (sh) 1994-09-09
NZ219445A (en) 1990-04-26
IL81686A (en) 1992-09-06
PL264488A1 (en) 1988-01-21
EP0237507B1 (de) 1991-12-27
IN168166B (de) 1991-02-16
SE8601060D0 (sv) 1986-03-07
ES2000997A4 (es) 1988-04-16
KR960007754B1 (ko) 1996-06-12
HU202763B (en) 1991-04-29
SE8601060L (sv) 1987-09-08
US4907583A (en) 1990-03-13
CA1276848C (en) 1990-11-27
PL149599B1 (en) 1990-02-28
SE453566B (sv) 1988-02-15
NO164001B (no) 1990-05-14
FI871000A7 (fi) 1987-09-08
SI8710341A (en) 1997-02-28
ATE70720T1 (de) 1992-01-15
JPS62221366A (ja) 1987-09-29

Similar Documents

Publication Publication Date Title
DE237507T1 (de) Vorrichtung zur inhalation von pulver.
DE69723202T2 (de) Inhalatoren
DE69420186T3 (de) Vernebler
EP0540775B1 (de) Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
EP0171726B1 (de) Inhalator
DE69525293T2 (de) Inhalationsgerät für medizinische Zwecke
EP0170715B1 (de) Zerstäubervorrichtung
DE69121724T2 (de) Pulverinhalator
DE69823565T2 (de) Zerstäuber
DE69528237T2 (de) Inhalator
DE69033607T2 (de) Vorrichtung zum wirkungsvollen Zerstäuben eines pulverförmigen Medikaments zur Inhalation
DE19520622C2 (de) Vorrichtung zum Vernebeln von Fluiden
EP0157250B1 (de) Vorrichtung zum Beizen von Saatgut
DE19700106A1 (de) Zerstäuber
EP0653218B1 (de) Zerstäubervorrichtung
DE2600862A1 (de) Inhalationseinrichtung
DE3043377A1 (de) Zerstaeuber
EP0601036A1 (de) Medizinisches gerät zur inhalation von dosier-aerosolen
DE3238149C2 (de) Vorrichtung zum Zerstäuben von Flüssigkeiten
DE10007591A1 (de) Medizinischer Vernebelungsapparat
DE69928377T2 (de) Pulverzuführungssystem
DE2201111A1 (de) Zerstaeubungstrocknungsvorrichtung zur Herstellung von Pulver,z.B. Milchpulver
WO2006094796A1 (de) Inhalator mit einem mischkanal zum erzeugen eines zu inhalierenden aerosols
EP0712637A1 (de) Abscheidesystem für einen Pulverinhalator
EP0572969A1 (de) Inhalator