DE237507T1 - Vorrichtung zur inhalation von pulver. - Google Patents
Vorrichtung zur inhalation von pulver.Info
- Publication number
- DE237507T1 DE237507T1 DE198787850060T DE87850060T DE237507T1 DE 237507 T1 DE237507 T1 DE 237507T1 DE 198787850060 T DE198787850060 T DE 198787850060T DE 87850060 T DE87850060 T DE 87850060T DE 237507 T1 DE237507 T1 DE 237507T1
- Authority
- DE
- Germany
- Prior art keywords
- unit
- air
- inhalation
- nozzle
- nozzle unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000843 powder Substances 0.000 title claims abstract 6
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 239000002245 particle Substances 0.000 claims abstract 3
- 238000010790 dilution Methods 0.000 claims 2
- 239000012895 dilution Substances 0.000 claims 2
- 241000509579 Draco Species 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Nozzles (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Inorganic Insulating Materials (AREA)
- External Artificial Organs (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Photoreceptors In Electrophotography (AREA)
- Disintegrating Or Milling (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Filtering Of Dispersed Particles In Gases (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Cyclones (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Gyroscopes (AREA)
- Amplifiers (AREA)
Claims (13)
1. Vorrichtung in Pulverinhalationseinrichtungen zum Inhalieren eines Luftstromes, der eine pharmakologisch aktive
Verbindung in atomisierter oder mikronisierter Form enthält und der eine Düseneinheit (2) aufweist mit einer Düsenöffnung
(2a) sowie eine Behältereinheit (3) mit einer Freigabe- oder Dosiereinheit (6) zur Abgabe der aktiven
Verbindung, wobei der durch die Inhalation erzeugte Luftstrom mindestens teilweise durch eine Luftleitung (7) in
der Behältereinheit (3) angesaugt wird und die Leitung, die sich von einem Lufteinlaß (8) erstreckt, mit der Umgebung
in Verbindung steht über die Freigabe- oder Dosiereinheit (6) bis zu der Düseneinheit (2) hin, gekennzeichnet
durch stationär in dem Behälter (3) und/oder der Duseneinheit
(2) angeordnete Ablenkvorrichtungen (13, 15, 16), die sich in wesentlichem Ausmaß zum Zentrum der Vorrichtungen
erstrecken und so angeordnet sind, daß sie der durch Inhalation erzeugten Luftströmung eine kräftige Ablenkbewegung
erteilen.
2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß
die Ablenkvorrichtungen (13, 15, 16) derart angeordnet sind, daß sie der durch Inhalation erzeugten Luftströmung
eine Drehbewegung erteilen.
3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, daß
längs der Mittelachse der Ablenkvorrichtungen (13, 15, 16) zur Verringerung des Fließwiderstandes ein durchgehendes
Loch angeordnet ist.
4. Vorrichtung nach Anspruch 3, dadurch gekennzeichnet, daß
das Verhältnis der radialen Erstreckung des Loches zu der der Ablenkvorrichtungen 0 - 50 % ist.
5. Vorrichtung nach Anspruch 1 oder 2, bei welcher mindestens
ein zusätzlicher Lufteinlaß (14, 14') in dem Behälter (3) oder der Düseneinheit (2) angeordnet ist für das
Einsaugen von Verdünnungsluft in den durch Inhalation erzeugten Luftstrom zwischen der Dosiereinheit (6) und der
Düsenöffnung (2a), dadurch gekennzeichnet, daß die Ablenkvorrichtungen (15, 16) derart angeordnet sind, daß
sie den Verdünnungsluftstrom und/oder den mit Partikeln gesättigten Luftstrom im Bereich der Luftleitung (7)
kräftig ablenken.
6. Vorrichtung nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet,
daß die Ablenkvorrichtungen mindestens einen im wesentlichen schraubenförmig gebildeten Kanalteil
(13, 15, 16) aufweisen.
7. Vorrichtung nach Anspruch 6, dadurch gekennzeichnet, daß mindestens ein schraubenförmiger Kanalteil (13), der mit
der Düsenöffnung (2a) verbunden ist, in der Düseneinheit
(2) angeordnet ist.
8. Vorrichtung nach Anspruch 7, dadurch gekennzeichnet, daß die Düseneinheit (2) zur Düsenöffnung (2a) hin mit einer
kontinuierlich abnehmenden Querschnittsfläche ausgestal-
tet ist. . .
9. Vorrichtung nach Anspruch 6 oder 7, dadurch gekennzeichnet, daß mindestens ein mit der Düseneinheit (2) verbundener
schraubenförmiger Kanalteil im Bereich der Luftlei-
OQ tung (7) angeordnet ist.
10. Vorrichtung nach Anspruch 7 oder 8, dadurch gekennzeichnet,
daß mindestens der Teil der Düseneinheit (2) neben der Behältereinheit (3) aus einer freien, inneren Kammer
(9) besteht, durch welche die durch Inhalation erzeugte Luftströmung hindurchgeht.
11. Vorrichtung nach einem der vorhergehenden Ansprüche in
Kombination mit Anspruch 5, bei welcher der zusätzliche Lufteinlaß (141) in der Behältereinheit (3) angeordnet
ist und dadurch gekennzeichnet ist, daß der zusätzliche Lufteinlaß (141) mit einem getrennten, schraubenförmigen
Kanalteil (16) verbunden ist, welches in der Luftleitung (7) oder der .Düseneinheit (2) endet.
12. Vorrichtung nach Anspruch 10, dadurch gekennzeichnet, daß der separate, schraubenförmige Kanalteil (16) in einer
Hülloberfläche angeordnet ist, welche die Luftleitung (7) umgibt.
13. Pulverinhalationseinrichtung nach einem der Ansprüche 6 bis 11, dadurch gekennzeichnet, daß die Querschnittsfläehe
des jeweiligen schraubenförmigen Kanalteils (13, 15, 16) 5-50 mm2 beträgt und daß die Gesamtlänge der schraubenförmigen Kanalteile 5 - 50 mm beträgt.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8601060A SE453566B (sv) | 1986-03-07 | 1986-03-07 | Anordning vid pulverinhalatorer |
| SG92094A SG92094G (en) | 1986-03-07 | 1994-07-11 | Device in powder inhalators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE237507T1 true DE237507T1 (de) | 1988-05-19 |
Family
ID=26659278
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE198787850060T Pending DE237507T1 (de) | 1986-03-07 | 1987-02-20 | Vorrichtung zur inhalation von pulver. |
| DE8787850060T Expired - Lifetime DE3775433D1 (de) | 1986-03-07 | 1987-02-20 | Vorrichtung zur inhalation von pulver. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8787850060T Expired - Lifetime DE3775433D1 (de) | 1986-03-07 | 1987-02-20 | Vorrichtung zur inhalation von pulver. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4907583A (de) |
| EP (1) | EP0237507B1 (de) |
| JP (1) | JPH0824715B2 (de) |
| KR (1) | KR960007754B1 (de) |
| AT (1) | ATE70720T1 (de) |
| AU (1) | AU601400B2 (de) |
| CA (1) | CA1276848C (de) |
| CY (1) | CY1798A (de) |
| DE (2) | DE237507T1 (de) |
| DK (1) | DK162424C (de) |
| EG (1) | EG18100A (de) |
| ES (1) | ES2000997T3 (de) |
| FI (1) | FI88679C (de) |
| GR (2) | GR880300028T1 (de) |
| HK (1) | HK80194A (de) |
| HR (1) | HRP920761B1 (de) |
| HU (1) | HU202763B (de) |
| IE (1) | IE60112B1 (de) |
| IL (1) | IL81686A (de) |
| IN (1) | IN168166B (de) |
| IS (1) | IS1390B6 (de) |
| NO (1) | NO164001C (de) |
| NZ (1) | NZ219445A (de) |
| PH (1) | PH25194A (de) |
| PL (1) | PL149599B1 (de) |
| PT (1) | PT84421B (de) |
| SE (1) | SE453566B (de) |
| SG (1) | SG92094G (de) |
| SI (1) | SI8710341B (de) |
| YU (1) | YU46977B (de) |
| ZA (1) | ZA871346B (de) |
Families Citing this family (274)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI84698C (fi) * | 1989-06-16 | 1992-01-10 | Huhtamaeki Oy | Anordning foer finfoerdelning av agglomerat av en enkeldos av ett laekemedelpreparat i pulverform. |
| SE9002895D0 (sv) * | 1990-09-12 | 1990-09-12 | Astra Ab | Inhalation devices for dispensing powders i |
| UA26915C2 (uk) * | 1990-09-12 | 1999-12-29 | Ханс БІСГОРД | Іhгаляторhий пристрій для вдихаhhя активhої порошкоподібhої або рідкої речовиhи |
| GB9021433D0 (en) * | 1990-10-02 | 1990-11-14 | Atomic Energy Authority Uk | Power inhaler |
| FR2667509B1 (fr) * | 1990-10-04 | 1995-08-25 | Valois | Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes. |
| AU654979B2 (en) * | 1990-10-05 | 1994-12-01 | University Of North Carolina At Chapel Hill, The | Method of administering amiloride |
| US5304125A (en) * | 1990-10-05 | 1994-04-19 | The University Of North Carolina | Apparatus for administering solid particulate aerosols to the lungs |
| DE59107894D1 (de) * | 1991-03-21 | 1996-07-11 | Ritzau Pari Werk Gmbh Paul | Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie |
| US5797391A (en) * | 1991-03-28 | 1998-08-25 | Rhone-Poulenc Rorer Limited | Inhaler |
| DK0533683T3 (da) * | 1991-04-15 | 1997-01-13 | Leiras Oy | Indretning til måling af en dosis pulveriseret medikament til inhalering |
| US5243970A (en) * | 1991-04-15 | 1993-09-14 | Schering Corporation | Dosing device for administering metered amounts of powdered medicaments to patients |
| US6681767B1 (en) | 1991-07-02 | 2004-01-27 | Nektar Therapeutics | Method and device for delivering aerosolized medicaments |
| ES2141108T3 (es) * | 1991-07-02 | 2000-03-16 | Inhale Inc | Metodo y dispositivo para proporcionar medicamentos en aerosol. |
| US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
| US6119688A (en) * | 1991-08-26 | 2000-09-19 | 3M Innovative Properties Company | Powder dispenser |
| US5469843A (en) * | 1991-11-12 | 1995-11-28 | Minnesota Mining And Manufacturing Company | Inhalation device |
| GB9123953D0 (en) * | 1991-11-12 | 1992-01-02 | Minnesota Mining & Mfg | Inhalation device |
| US5476093A (en) * | 1992-02-14 | 1995-12-19 | Huhtamaki Oy | Device for more effective pulverization of a powdered inhalation medicament |
| DE4208880A1 (de) * | 1992-03-19 | 1993-09-23 | Boehringer Ingelheim Kg | Separator fuer pulverinhalatoren |
| US5394868A (en) * | 1992-06-25 | 1995-03-07 | Schering Corporation | Inhalation device for powdered medicaments |
| US6673335B1 (en) * | 1992-07-08 | 2004-01-06 | Nektar Therapeutics | Compositions and methods for the pulmonary delivery of aerosolized medicaments |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| US6509006B1 (en) | 1992-07-08 | 2003-01-21 | Inhale Therapeutic Systems, Inc. | Devices compositions and methods for the pulmonary delivery of aerosolized medicaments |
| ES2179831T3 (es) * | 1992-09-29 | 2003-02-01 | Inhale Therapeutic Syst | Liberacion en los pulmones de fragmentos activos de hormona paratiroidiana. |
| DE4237568C1 (de) * | 1992-11-06 | 1994-05-11 | Dieter Dipl Ing Dr Med Koehler | Verfahren und Vorrichtung zum Erzeugen eines Aerosols |
| DE4239402A1 (de) * | 1992-11-24 | 1994-05-26 | Bayer Ag | Pulverinhalator |
| SE9203743D0 (sv) * | 1992-12-11 | 1992-12-11 | Astra Ab | Efficient use |
| US6250300B1 (en) | 1992-12-11 | 2001-06-26 | Ab Astra | System for dispensing pharmaceutically active compounds |
| WO1994014492A2 (en) * | 1992-12-18 | 1994-07-07 | Schering Corporation | Inhaler for powdered medications |
| US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
| US7448375B2 (en) * | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
| EP0691864A4 (de) * | 1993-03-03 | 1996-07-03 | Tenax Corp | Medikamententräger für trockenpuverinhalator |
| GB9306703D0 (en) * | 1993-03-31 | 1993-05-26 | Fisons Plc | Inhalation device |
| DE69413528T2 (de) * | 1993-04-06 | 1999-05-06 | Minnesota Mining And Mfg. Co., Saint Paul, Minn. | Vorrichtung zum deagglomerieren für trockenpulverinhalatoren |
| US5533502A (en) * | 1993-05-28 | 1996-07-09 | Vortran Medical Technology, Inc. | Powder inhaler with aerosolization occurring within each individual powder receptacle |
| TW402506B (en) | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
| US6794357B1 (en) * | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
| US5747445A (en) * | 1993-06-24 | 1998-05-05 | Astra Aktiebolag | Therapeutic preparation for inhalation |
| US20010003739A1 (en) * | 1993-06-24 | 2001-06-14 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
| IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| US5506203C1 (en) * | 1993-06-24 | 2001-02-06 | Astra Ab | Systemic administration of a therapeutic preparation |
| US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
| US5830853A (en) | 1994-06-23 | 1998-11-03 | Astra Aktiebolag | Systemic administration of a therapeutic preparation |
| US5388572A (en) * | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
| WO1995012428A1 (de) * | 1993-10-30 | 1995-05-11 | Koehler Dieter | Verfahren und vorrichtung zum erzeugen eines aerosols aus einer pulverförmigen substanz |
| DE4340768A1 (de) * | 1993-11-30 | 1995-06-01 | Bayer Ag | Vorrichtung zum Inhalieren |
| US5388573A (en) * | 1993-12-02 | 1995-02-14 | Tenax Corporation | Dry powder inhalator medicament carrier |
| GB9326574D0 (en) * | 1993-12-31 | 1994-03-02 | King S College London | Dry power inhalers |
| DE4400084C2 (de) * | 1994-01-04 | 2001-08-02 | Softec Gmbh & Co Kg | Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form |
| PT101450B (pt) * | 1994-02-02 | 1999-11-30 | Hovione Produtos Farmaceuticos | Novo dispositivo para inalacao |
| US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| WO1995024183A1 (en) * | 1994-03-07 | 1995-09-14 | Inhale Therapeutic Systems | Methods and compositions for pulmonary delivery of insulin |
| AU124387S (en) * | 1994-03-25 | 1995-08-11 | Astra Ab | Training device for an inhaler |
| EP0759939B1 (de) * | 1994-05-18 | 2005-07-20 | Nektar Therapeutics | Methoden und zusammensetzungen für die trockenpuderarznei aus interferonen |
| US6165976A (en) | 1994-06-23 | 2000-12-26 | Astra Aktiebolag | Therapeutic preparation for inhalation |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| JP3706136B2 (ja) | 1994-09-21 | 2005-10-12 | ネクター セラピューティクス | 乾燥粉末薬剤の分散装置及び方法 |
| DE4440734A1 (de) * | 1994-11-15 | 1996-05-23 | Bayer Ag | Abscheidesystem für einen Pulverinhalator |
| SE9404439D0 (sv) * | 1994-12-21 | 1994-12-21 | Astra Ab | Inhalation device |
| ATE236617T1 (de) | 1994-12-22 | 2003-04-15 | Astrazeneca Ab | Aerosol-arzneiformulierungen |
| US6524557B1 (en) * | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| CZ182297A3 (cs) * | 1994-12-22 | 1998-01-14 | Astra Aktiebolag | Terapeutický přípravek pro inhalaci obsahující parathyroidní hormon, PTH |
| DE19500764C2 (de) * | 1995-01-13 | 2001-09-27 | Sofotec Gmbh & Co Kg | Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form |
| US5780014A (en) * | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US6428771B1 (en) | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
| US5654007A (en) * | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| SE9502799D0 (sv) * | 1995-08-10 | 1995-08-10 | Astra Ab | Device in inhalers |
| SE9502800D0 (sv) * | 1995-08-10 | 1995-08-10 | Astra Ab | Disposable inhaler |
| SE9503344D0 (sv) | 1995-09-27 | 1995-09-27 | Astra Ab | Inhalation device |
| US7131441B1 (en) | 1995-12-07 | 2006-11-07 | Skyepharma Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
| US6182655B1 (en) | 1995-12-07 | 2001-02-06 | Jago Research Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
| US5669378A (en) * | 1995-12-21 | 1997-09-23 | Pera; Ivo | Inhaling device |
| ATE209939T1 (de) * | 1996-01-03 | 2001-12-15 | Glaxo Group Ltd | Inhalator |
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| SE9700937D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler I |
| SE9700940D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler IV |
| SE9700943D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler V |
| SE9700948D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler X |
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| SE9700944D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler VI |
| US20030035778A1 (en) * | 1997-07-14 | 2003-02-20 | Robert Platz | Methods and compositions for the dry powder formulation of interferon |
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| US6293279B1 (en) | 1997-09-26 | 2001-09-25 | Trudell Medical International | Aerosol medication delivery apparatus and system |
| US6345617B1 (en) * | 1997-09-26 | 2002-02-12 | 1263152 Ontario Inc. | Aerosol medication delivery apparatus and system |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) * | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
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| US1309597A (en) * | 1919-07-08 | parker | ||
| US1431177A (en) * | 1919-06-06 | 1922-10-10 | Palmer Richard | Inhaling device |
| GB682069A (en) * | 1949-04-14 | 1952-11-05 | Airmed Ltd | Improvements in and relating to controlling the supply of vapours of volatile liquids |
| US2604094A (en) * | 1949-06-25 | 1952-07-22 | Schenley Ind Inc | Inhaler |
| US2804341A (en) * | 1956-04-13 | 1957-08-27 | Bete Fog Nozzle Inc | Spray nozzles |
| US4014470A (en) * | 1976-03-01 | 1977-03-29 | Bete Fog Nozzle, Inc. | Conical spray nozzle |
| US4147166A (en) * | 1977-05-02 | 1979-04-03 | American Cyanamid Company | Oral inhalator powder dispenser |
| NL8020393A (de) * | 1979-10-30 | 1981-09-01 | Riker Laboratories, Inc. Te Loughborough, Groot-Brittannie. | |
| BR8007911A (pt) * | 1979-12-06 | 1981-06-16 | Glaxo Group Ltd | Inalador aperfeicoado |
| DE3043377A1 (de) * | 1980-11-17 | 1982-07-01 | Brugger, Inge, 8130 Starnberg | Zerstaeuber |
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| US4570630A (en) * | 1983-08-03 | 1986-02-18 | Miles Laboratories, Inc. | Medicament inhalation device |
| GB2152819B (en) * | 1983-12-08 | 1988-05-11 | Anthony John Dyson | Improved nebuliser |
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1986
- 1986-03-07 SE SE8601060A patent/SE453566B/sv not_active IP Right Cessation
-
1987
- 1987-02-20 AT AT87850060T patent/ATE70720T1/de not_active IP Right Cessation
- 1987-02-20 DE DE198787850060T patent/DE237507T1/de active Pending
- 1987-02-20 EP EP87850060A patent/EP0237507B1/de not_active Expired - Lifetime
- 1987-02-20 DE DE8787850060T patent/DE3775433D1/de not_active Expired - Lifetime
- 1987-02-20 ES ES198787850060T patent/ES2000997T3/es not_active Expired - Lifetime
- 1987-02-24 IN IN156/DEL/87A patent/IN168166B/en unknown
- 1987-02-24 ZA ZA871346A patent/ZA871346B/xx unknown
- 1987-02-24 IS IS3196A patent/IS1390B6/is unknown
- 1987-02-26 IL IL81686A patent/IL81686A/xx not_active IP Right Cessation
- 1987-03-02 NZ NZ219445A patent/NZ219445A/en unknown
- 1987-03-02 AU AU69604/87A patent/AU601400B2/en not_active Expired
- 1987-03-02 IE IE52987A patent/IE60112B1/en not_active IP Right Cessation
- 1987-03-03 EG EG118/87A patent/EG18100A/xx active
- 1987-03-04 PH PH34957A patent/PH25194A/en unknown
- 1987-03-04 SI SI8710341A patent/SI8710341B/sl unknown
- 1987-03-04 YU YU34187A patent/YU46977B/sh unknown
- 1987-03-06 CA CA000531324A patent/CA1276848C/en not_active Expired - Lifetime
- 1987-03-06 DK DK115487A patent/DK162424C/da not_active IP Right Cessation
- 1987-03-06 HU HU87975A patent/HU202763B/hu unknown
- 1987-03-06 PT PT84421A patent/PT84421B/pt unknown
- 1987-03-06 FI FI871000A patent/FI88679C/fi not_active IP Right Cessation
- 1987-03-06 PL PL1987264488A patent/PL149599B1/pl unknown
- 1987-03-06 KR KR1019870001999A patent/KR960007754B1/ko not_active Expired - Lifetime
- 1987-03-06 NO NO870938A patent/NO164001C/no unknown
- 1987-03-06 JP JP62050419A patent/JPH0824715B2/ja not_active Expired - Lifetime
-
1988
- 1988-05-20 GR GR88300028T patent/GR880300028T1/el unknown
- 1988-12-16 US US07/287,611 patent/US4907583A/en not_active Expired - Lifetime
-
1991
- 1991-12-30 GR GR91401976T patent/GR3003451T3/el unknown
-
1992
- 1992-10-01 HR HRP-141/87A patent/HRP920761B1/xx not_active IP Right Cessation
-
1994
- 1994-07-11 SG SG92094A patent/SG92094G/en unknown
- 1994-08-11 HK HK80194A patent/HK80194A/en not_active IP Right Cessation
-
1995
- 1995-02-17 CY CY179895A patent/CY1798A/xx unknown
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