DE122008000069I1 - Schweinecircoviren abgeleitete impfstoffe - Google Patents

Schweinecircoviren abgeleitete impfstoffe

Info

Publication number: DE122008000069I1
Authority: DE; Germany
Prior art keywords: pcv; orfs; antigen; preparation; vector
Prior art date: 1997-10-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

DE122008000069C

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Animal Health France SAS

Original Assignee

Merial SAS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-03

Filing date

1998-10-01

Publication date

2009-11-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27253376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122008000069(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-10-03 Priority claimed from FR9712382A external-priority patent/FR2769321B1/fr

1998-01-22 Priority claimed from FR9800873A external-priority patent/FR2769322B1/fr

1998-03-20 Priority claimed from FR9803707A external-priority patent/FR2776294B1/fr

1998-10-01 Application filed by Merial SAS filed Critical Merial SAS

2009-11-05 Publication of DE122008000069I1 publication Critical patent/DE122008000069I1/de

Status Pending legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0321—Propionic acid bacteria
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0323—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin using only lactic acid bacteria, e.g. Pediococcus and Leuconostoc species; Bifidobacteria; Microbial starters in general
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16741—Use of virus, viral particle or viral elements as a vector
- C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10041—Use of virus, viral particle or viral elements as a vector
- C12N2750/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10061—Methods of inactivation or attenuation
- C12N2750/10064—Methods of inactivation or attenuation by serial passage

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Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Microbiology (AREA)
Immunology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Polymers & Plastics (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Food Science & Technology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Mycology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

DE122008000069C 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete impfstoffe Pending DE122008000069I1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR9712382A FR2769321B1 (fr)	1997-10-03	1997-10-03	Nouveaux circovirus porcins, vaccins et reactifs de diagnostics
FR9800873A FR2769322B1 (fr)	1997-10-03	1998-01-22	Nouveaux circovirus porcins, vaccins et reactifs de diagnostic
FR9803707A FR2776294B1 (fr)	1998-03-20	1998-03-20	Nouveaux circovirus porcins ; vaccins et reactifs de diagnostic
PCT/FR1998/002107 WO1999018214A1 (fr)	1997-10-03	1998-10-01	Circovirus porcins, vaccins et reactifs de diagnostic

Publications (1)

Publication Number	Publication Date
DE122008000069I1 true DE122008000069I1 (de)	2009-11-05

Family

ID=27253376

Family Applications (7)

Application Number	Title	Priority Date	Filing Date
DE69816460T Expired - Lifetime DE69816460T2 (de)	1997-10-03	1998-10-01	Schweinecircoviren abgeleitete impfstoffe
DE69830858T Expired - Lifetime DE69830858T4 (de)	1997-10-03	1998-10-01	Schweinecircoviren
DE69830858A Expired - Lifetime DE69830858D1 (de)	1997-10-03	1998-10-01	Schweinecircoviren
DE05014998T Pending DE05014998T1 (de)	1997-10-03	1998-10-01	Schweinecircoviren, Nukleinsäuren, Polypeptide und Impfstoffe
DE69839227T Expired - Lifetime DE69839227T2 (de)	1997-10-03	1998-10-01	Verfahren zur in vitro-Diagnose von Infektionen durch Schweinecircovirus vom Typ II und diagnostische Reagenzien
DE200512000009 Pending DE122005000009I1 (de)	1997-10-03	1998-10-01	Schweinecircoviren abgeleitete Impfstoffe.
DE122008000069C Pending DE122008000069I1 (de)	1997-10-03	1998-10-01	Schweinecircoviren abgeleitete impfstoffe

Family Applications Before (6)

Application Number	Title	Priority Date	Filing Date
DE69816460T Expired - Lifetime DE69816460T2 (de)	1997-10-03	1998-10-01	Schweinecircoviren abgeleitete impfstoffe
DE69830858T Expired - Lifetime DE69830858T4 (de)	1997-10-03	1998-10-01	Schweinecircoviren
DE69830858A Expired - Lifetime DE69830858D1 (de)	1997-10-03	1998-10-01	Schweinecircoviren
DE05014998T Pending DE05014998T1 (de)	1997-10-03	1998-10-01	Schweinecircoviren, Nukleinsäuren, Polypeptide und Impfstoffe
DE69839227T Expired - Lifetime DE69839227T2 (de)	1997-10-03	1998-10-01	Verfahren zur in vitro-Diagnose von Infektionen durch Schweinecircovirus vom Typ II und diagnostische Reagenzien
DE200512000009 Pending DE122005000009I1 (de)	1997-10-03	1998-10-01	Schweinecircoviren abgeleitete Impfstoffe.

Country Status (20)

Country	Link
US (1)	US6368601B1 (de)
EP (4)	EP1386617B1 (de)
JP (5)	JP5008218B2 (de)
KR (4)	KR100736129B1 (de)
CN (2)	CN100584948C (de)
AT (3)	ATE299531T1 (de)
AU (1)	AU756554C (de)
BR (1)	BR9812845B1 (de)
CA (1)	CA2305623C (de)
CY (3)	CY1110359T1 (de)
DE (7)	DE69816460T2 (de)
DK (4)	DK1281760T5 (de)
ES (4)	ES2246001T3 (de)
FR (1)	FR05C0021I2 (de)
HU (2)	HU230340B1 (de)
NL (1)	NL300326I2 (de)
PL (1)	PL198506B1 (de)
PT (4)	PT1019510E (de)
UA (1)	UA78180C2 (de)
WO (1)	WO1999018214A1 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
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US6517843B1 (en)	1999-08-31	2003-02-11	Merial	Reduction of porcine circovirus-2 viral load with inactivated PCV-2
FR2781159B1 (fr) *	1998-07-06	2000-10-06	Merial Sas	Vaccin circovirus et parvovirus porcin
US7192594B2 (en)	1997-10-03	2007-03-20	Merial Limited	Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US20060029617A1 (en) *	1997-10-03	2006-02-09	Charreyre Catherine E	Porcine circovirus and Helicobacter combination vaccines and methods of use
US6391314B1 (en) *	1997-10-03	2002-05-21	Merial	Porcine circoviruses vaccines diagnostic reagents
US7211379B2 (en) *	1997-10-03	2007-05-01	Merial Sas	Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
FR2772047B1 (fr) *	1997-12-05	2004-04-09	Ct Nat D Etudes Veterinaires E	Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US20040062775A1 (en) *	1997-12-05	2004-04-01	Agence Francaise De Securite Sanitaire Des Aliments	Circovirus sequences associated with piglet weight loss disease (PWD)
JP3795751B2 (ja) *	1997-12-11	2006-07-12	ユニバーシティオブサスカッチェワン	ブタからの離乳後多全身系消耗症候群ウイルス
EP1816200B1 (de)	1997-12-11	2016-03-09	Merial	Virus des multisystemischen Kümmersyndroms bei Absatzferkeln
US6943152B1 (en) *	1999-06-10	2005-09-13	Merial	DNA vaccine-PCV
US6497883B1 (en) *	1999-06-10	2002-12-24	Merial	Porcine circovirus recombinant poxvirus vaccine
ES2170622B1 (es) *	1999-12-03	2004-05-16	Consejo Superior De Investigaciones Cientificas	Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
EP1290016A2 (de) *	2000-06-15	2003-03-12	Purdue Research Foundation	Impfstoff gegen kongenitales tremor bei schweinen
US7018638B2 (en) *	2000-12-19	2006-03-28	Wyeth	Mycoplasma hyopneumoniae bacterin vaccine
CZ304525B6 (cs)	2001-03-27	2014-06-18	University Of Saskatchewan	Způsob kultivace circoviru
HRP20040078A2 (en)	2001-07-20	2004-08-31	Univ Georgia Res Fundation	Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the cns
US7279166B2 (en)	2001-12-12	2007-10-09	Virginia Tech Intellectual Properties, Inc.	Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7276353B2 (en) *	2001-12-12	2007-10-02	Virginia Tech Intellectual Properties, Inc.	Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
EP1743652B1 (de) *	2002-08-26	2011-11-16	Pfizer Products Inc.	Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Rindern
KR20040021988A (ko) *	2002-09-06	2004-03-11	서상희	바이러스 증식용 돼지 신장 상피 세포주, 및 이의 용도
UA95602C2 (ru)	2004-12-30	2011-08-25	Берингер Ингельхейм Ветмедика, Инк.	Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en)	2005-12-29	2010-04-20	Boehringer Ingelheim Vetmedica, Inc.	PCV2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en) *	2004-12-30	2010-11-16	Boehringer Ingelheim Vetmedica, Inc.	Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US8834891B2 (en)	2005-03-14	2014-09-16	Boehringer Ingelheim Vetmedica, Inc.	Immunogenic compositions comprising Lawsonia intracellularis
WO2006113435A2 (en) *	2005-04-13	2006-10-26	Merial Limited	Method for porcine circovirus production and assays for monitoring production
EP1792996A1 (de) *	2005-12-01	2007-06-06	Consejo Superior de Investigaciones Cientificas	Nukleinsäuren, kodierend für Impfstoffe gegen den reproduktiven und respiratorischen Syndrom Virus (prrsv)
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HU226247B1 (en)	2008-07-28
CA2305623A1 (fr)	1999-04-15
ES2246001T3 (es)	2006-02-01
KR100736129B1 (ko)	2007-07-06
CA2305623C (en)	2008-04-01
KR20090051274A (ko)	2009-05-21
NL300326I1 (nl)	2008-03-03
CY1108113T1 (el)	2014-02-12
EP1019510A1 (de)	2000-07-19
KR100904852B1 (ko)	2009-06-25
JP5008218B2 (ja)	2012-08-22
JP5869658B2 (ja)	2016-02-24
EP1386617B1 (de)	2008-03-05
KR20010030930A (ko)	2001-04-16
WO1999018214A1 (fr)	1999-04-15
ATE299531T1 (de)	2005-07-15
BR9812845A (pt)	2000-08-08
HUP0003756A2 (hu)	2001-02-28
CN101724606B (zh)	2016-02-24
US6368601B1 (en)	2002-04-09
EP1019510B1 (de)	2003-07-16
CY1115749T1 (el)	2017-01-25
HUP0003756A3 (en)	2003-03-28
EP1281760B9 (de)	2005-12-28
DE69830858T4 (de)	2006-12-21
FR05C0021I1 (de)	2005-05-27
DK1281760T3 (da)	2005-10-31
KR100854615B1 (ko)	2008-08-27
DE69830858T2 (de)	2006-04-20
JP2011135875A (ja)	2011-07-14
PL339631A1 (en)	2001-01-02
DE69839227D1 (de)	2008-04-17
ES2524359T3 (es)	2014-12-05
DK1019510T3 (da)	2003-11-10
HU0800330D0 (en)	2008-07-28
DE122005000009I1 (de)	2005-08-04
EP1741785B1 (de)	2014-10-01
CN100584948C (zh)	2010-01-27
DE69816460T2 (de)	2004-05-27
PL198506B1 (pl)	2008-06-30
DK1386617T3 (da)	2008-07-07
JP4680245B2 (ja)	2011-05-11
FR05C0021I2 (de)	2005-10-21
JP2008086317A (ja)	2008-04-17
EP1281760A1 (de)	2003-02-05
JP2001519159A (ja)	2001-10-23
ATE245191T1 (de)	2003-08-15
EP1386617A1 (de)	2004-02-04
KR20060079256A (ko)	2006-07-05
KR100944144B1 (ko)	2010-02-24
PT1741785E (pt)	2014-11-13
AU756554C (en)	2003-09-18
ATE387914T1 (de)	2008-03-15
KR20080023271A (ko)	2008-03-12
UA78180C2 (uk)	2007-03-15
CY1110359T1 (el)	2015-04-29
ES2203984T3 (es)	2004-04-16
CN101724606A (zh)	2010-06-09
AU9355598A (en)	1999-04-27
BR9812845B1 (pt)	2010-03-09
EP1741785A1 (de)	2007-01-10
PT1281760E (pt)	2005-11-30
DK1741785T3 (da)	2014-11-10
DE69830858D1 (de)	2005-08-18
CN1278301A (zh)	2000-12-27
JP2012193179A (ja)	2012-10-11
PT1019510E (pt)	2003-11-28
HU230340B1 (hu)	2016-02-29
DK1281760T5 (da)	2006-04-18
PT1386617E (pt)	2008-06-17
EP1281760B1 (de)	2005-07-13
NL300326I2 (nl)	2008-04-01
AU756554B2 (en)	2003-01-16
JP5362750B2 (ja)	2013-12-11
DE69839227T2 (de)	2009-03-12
DE69816460D1 (de)	2003-08-21
DE05014998T1 (de)	2008-11-20
ES2302885T3 (es)	2008-08-01
JP2015109840A (ja)	2015-06-18
HK1095161A1 (en)	2007-04-27

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