DE122004000048I2 - Neue Chinuclidin-Derivate und diese enthaltende pharmazeutische Pr{parate - Google Patents
Neue Chinuclidin-Derivate und diese enthaltende pharmazeutische Pr{parateInfo
- Publication number
- DE122004000048I2 DE122004000048I2 DE200412000048 DE122004000048C DE122004000048I2 DE 122004000048 I2 DE122004000048 I2 DE 122004000048I2 DE 200412000048 DE200412000048 DE 200412000048 DE 122004000048 C DE122004000048 C DE 122004000048C DE 122004000048 I2 DE122004000048 I2 DE 122004000048I2
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical preparations
- quinuclidine derivatives
- preparations containing
- diseases
- new quinuclidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000008584 quinuclidines Chemical class 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 102000007202 Muscarinic M3 Receptor Human genes 0.000 abstract 1
- 108010008405 Muscarinic M3 Receptor Proteins 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 208000012931 Urologic disease Diseases 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000010643 digestive system disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000014001 urinary system disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K19/00—Liquid crystal materials
- C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
- C09K19/06—Non-steroidal liquid crystal compounds
- C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
- C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
- C09K19/3444—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing one nitrogen atom, e.g. pyridine
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Tea And Coffee (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32704594 | 1994-12-28 | ||
| PCT/JP1995/002713 WO1996020194A1 (en) | 1994-12-28 | 1995-12-27 | Novel quinuclidine derivatives and medicinal composition thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE122004000048I1 DE122004000048I1 (de) | 2005-04-21 |
| DE122004000048I2 true DE122004000048I2 (de) | 2006-02-02 |
Family
ID=18194699
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE200412000048 Active DE122004000048I2 (de) | 1994-12-28 | 1995-12-27 | Neue Chinuclidin-Derivate und diese enthaltende pharmazeutische Pr{parate |
| DE69529844T Expired - Lifetime DE69529844T2 (de) | 1994-12-28 | 1995-12-27 | Neue chinuclidin-derivate und diese enthaltende pharmazeutische präparate |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69529844T Expired - Lifetime DE69529844T2 (de) | 1994-12-28 | 1995-12-27 | Neue chinuclidin-derivate und diese enthaltende pharmazeutische präparate |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US6017927A (de) |
| EP (1) | EP0801067B1 (de) |
| JP (1) | JP3014457B2 (de) |
| KR (1) | KR100386487B1 (de) |
| CN (1) | CN1045601C (de) |
| AT (1) | ATE233761T1 (de) |
| AU (1) | AU695616B2 (de) |
| CA (1) | CA2208839C (de) |
| DE (2) | DE122004000048I2 (de) |
| DK (1) | DK0801067T3 (de) |
| ES (1) | ES2193208T3 (de) |
| FI (1) | FI115631B (de) |
| FR (1) | FR04C0032I2 (de) |
| HU (1) | HU223778B1 (de) |
| LU (1) | LU91133I9 (de) |
| MX (1) | MX9704880A (de) |
| NL (1) | NL300141I1 (de) |
| NO (4) | NO2005012I1 (de) |
| NZ (1) | NZ298144A (de) |
| PL (1) | PL182344B1 (de) |
| PT (1) | PT801067E (de) |
| RU (1) | RU2143432C1 (de) |
| TW (1) | TW305842B (de) |
| WO (1) | WO1996020194A1 (de) |
Families Citing this family (104)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100137358A1 (en) * | 1996-11-05 | 2010-06-03 | Dr. Reddy's Laboratories Ltd. | Solifenacin compositions |
| FR2772378B1 (fr) * | 1997-12-12 | 2000-02-04 | Synthelabo | Derives d'imidazole, leur preparation et leur application en therapeutique |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| US7214687B2 (en) | 1999-07-14 | 2007-05-08 | Almirall Ag | Quinuclidine derivatives and medicinal compositions containing the same |
| JP2001316670A (ja) * | 2000-05-02 | 2001-11-16 | Dainippon Ink & Chem Inc | 液晶組成物 |
| DK1300407T4 (da) * | 2000-06-27 | 2011-09-05 | S A L V A T Lab Sa | Carbamater afledt af arylalkylaminer |
| HUP0303529A3 (en) * | 2000-12-22 | 2008-03-28 | Almirall Ag | New quinuclidine carbamate derivatives, process for their preparation and pharmaceutical compositions containing them and their use |
| SK287414B6 (sk) | 2000-12-28 | 2010-09-07 | Laboratorios Almirall, S.A. | Chinuklidínové deriváty a kompozície s ich obsahom |
| DK1405638T3 (da) * | 2001-07-10 | 2011-04-18 | Astellas Pharma Inc | Farmaceutisk sammensætning omfattende quinuclidin-3'-yl-1-phenyl-1,2,3,4,-tetrahydroisoquinolin-2-carboxylat til behandling af interstitiel cystitis og/eller abakteriel prostatitis |
| EP1461336B1 (de) | 2001-12-20 | 2013-05-22 | CHIESI FARMACEUTICI S.p.A. | 1-alkyl-1-azoniabicyclo (2.2.2) octan carbamatderivate und deren verwendung als muscarinische rezeptor antagonisten |
| EP1552825A4 (de) * | 2002-06-07 | 2009-11-25 | Astellas Pharma Inc | THERAPEUTISCHES MITTEL GEGEN BLASEN BERAKTIVITûT |
| ES2203327B1 (es) * | 2002-06-21 | 2005-06-16 | Almirall Prodesfarma, S.A. | Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen. |
| ES2204295B1 (es) | 2002-07-02 | 2005-08-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de quinuclidina-amida. |
| DE60230683D1 (de) | 2002-07-08 | 2009-02-12 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo-3.1.0 hexan-derivat |
| HK1079787A1 (zh) | 2002-07-31 | 2006-04-13 | Ranbaxy Laboratories Limited | 用作毒蕈碱受体拮抗剂的3,6-二取代的氮杂双环[3.1.0]己烷衍生物 |
| EP1545508A4 (de) | 2002-08-09 | 2009-11-25 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo ¬3.1.0 hexan-derivate als muscarinische rezeptor-antagonisten |
| US7288562B2 (en) | 2002-08-23 | 2007-10-30 | Ranbaxy Laboratories Limited | Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists |
| AU2003269380A1 (en) * | 2002-10-29 | 2004-05-25 | Pharmacia & Upjohn Company Llc | Quinuclidinium derivatives as antimuscarinic agents |
| US7232835B2 (en) | 2002-12-10 | 2007-06-19 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists |
| ES2288641T3 (es) * | 2002-12-20 | 2008-01-16 | Dynogen Pharmaceuticals Inc. | Metodo para tratar trastornos indoloros de la vejiga usando moduladores de canales del calcio de la subunidad alfa2-delta. |
| US7465751B2 (en) | 2002-12-23 | 2008-12-16 | Ranbaxy Laboratories Limited | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists |
| WO2004056811A1 (en) * | 2002-12-23 | 2004-07-08 | Ranbaxy Laboratories Limited | Flavaxate derivatives as muscarinic receptor antagonists |
| US7488748B2 (en) | 2003-01-28 | 2009-02-10 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| DE602004003172T2 (de) * | 2003-03-21 | 2007-09-27 | Dynogen Pharmaceuticals Inc., Waltham | Verfahren zur behandlung von erkrankungen der unteren harnwege mit antimuskarinika und mit modulatoren der alpha-2-delta untereinheit des kalziumkanals |
| WO2004089898A1 (en) | 2003-04-09 | 2004-10-21 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| EP1615634B1 (de) | 2003-04-10 | 2007-05-16 | Ranbaxy Laboratories, Ltd. | Substituierte azabicyclo hexane derivate als muscarin rezeptor antagonisten |
| AU2003223010A1 (en) | 2003-04-10 | 2004-11-01 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| US20070021487A1 (en) | 2003-04-11 | 2007-01-25 | Mohammad Salman | Azabicyclo derivatives as muscarinic receptor antagonists |
| WO2004091597A2 (en) * | 2003-04-15 | 2004-10-28 | Pharmacia & Upjohn Company Llc | Method of treating irritable bowel syndrome (ibs) |
| US20050175689A1 (en) * | 2003-10-27 | 2005-08-11 | Yamanouchi Pharmaceutical Co., Ltd. | Coated fine particles containing drug for intrabuccally fast disintegrating tablet |
| JPWO2005075474A1 (ja) * | 2004-02-09 | 2007-10-11 | アステラス製薬株式会社 | コハク酸ソリフェナシン含有組成物 |
| WO2005077364A1 (ja) * | 2004-02-18 | 2005-08-25 | Yamanouchi Pharmaceutical Co., Ltd. | ソリフェナシンの経皮投与製剤およびその経皮透過改善方法 |
| ES2239546B1 (es) * | 2004-03-15 | 2006-12-01 | Almirall Prodesfarma, S.A. | Nuevos esteres de quinuclidina cuaternizados. |
| CA2560080A1 (en) * | 2004-03-16 | 2005-09-22 | Astellas Pharma Inc. | Solifenacin-containing composition |
| JPWO2005087231A1 (ja) * | 2004-03-16 | 2008-01-24 | アステラス製薬株式会社 | ソリフェナシン含有組成物 |
| PT2156824E (pt) | 2004-03-25 | 2013-01-04 | Astellas Pharma Inc | Uma composição de solifenacina, ou um seu sal, utilizada sob a forma de formulações sólidas |
| ZA200608614B (en) * | 2004-03-25 | 2008-06-25 | Astellas Pharma Inc | Composition for solid pharmaceutical preparation of solifenacin or salt thereof |
| SE0400970D0 (sv) * | 2004-04-14 | 2004-04-14 | Astrazeneca Ab | Nicotinic acetylcholine receptor ligands |
| WO2006035280A1 (en) * | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | 3,4-dihydroisoquinoline compounds as muscrinic receptor antagonists for the treatment of respiratory, urinary and gastrointestinal diseases |
| US20090105221A1 (en) * | 2004-09-29 | 2009-04-23 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| MX2007007328A (es) * | 2004-12-22 | 2007-07-25 | Memory Pharm Corp | Ligandos del receptor alfa-7 nicotinico y preparacion y sus usos. |
| BG1677U1 (bg) * | 2004-12-27 | 2013-04-30 | Astellas Pharma Inc.Astellas Pharma Inc. | Фармацевтичен състав със стабилни частици на солифенацин или негова сол |
| CA2591761A1 (en) * | 2004-12-27 | 2006-07-06 | Astellas Pharma Inc. | Stable particulate pharmaceutical composition of solifenacin or salt thereof |
| EP1852117A4 (de) * | 2005-02-25 | 2010-10-27 | Astellas Pharma Inc | Solifenacin enthaltendes pharmazeutisches mittel |
| JP3701964B1 (ja) | 2005-03-08 | 2005-10-05 | アステラス製薬株式会社 | キヌクリジン誘導体の新規な塩 |
| US20080255188A1 (en) * | 2005-07-11 | 2008-10-16 | Naresh Kumar | Muscarinic Receptor Antagonists |
| US7815939B2 (en) * | 2005-07-20 | 2010-10-19 | Astellas Pharma Inc. | Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms |
| WO2007045979A1 (en) | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of muscarinic receptor antagonists |
| JP2008535931A (ja) * | 2005-12-21 | 2008-09-04 | テバ ファーマシューティカル インダストリーズ リミティド | ソリフェナシンの調製方法 |
| CZ300699B6 (cs) * | 2006-06-21 | 2009-07-22 | Zentiva, A. S. | Zpusob prípravy solifenacinu |
| US20090326230A1 (en) * | 2006-07-19 | 2009-12-31 | Dr. Reddy's Laboratories Ltd. | Process for preparing solifenacin and its salts |
| ES2298049B1 (es) * | 2006-07-21 | 2009-10-20 | Laboratorios Almirall S.A. | Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano. |
| EP2043639A2 (de) * | 2006-07-24 | 2009-04-08 | Teva Pharmaceutical Industries Ltd. | Verfahren zur herstellung polymorpher formen von solifenacin-succinat |
| US20080114029A1 (en) * | 2006-08-03 | 2008-05-15 | Tamas Koltai | Polymorphs of solifenacin intermediate |
| TW200825084A (en) * | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
| EP2102200A2 (de) * | 2006-11-22 | 2009-09-23 | Medichem, S.A. | Verbessertes verfahren für die synthese von solifenacin |
| CZ300692B6 (cs) * | 2006-12-22 | 2009-07-15 | Zentiva, A. S. | Zpusob prípravy solifenacinu |
| CA2682381A1 (en) * | 2007-03-30 | 2008-10-09 | Medichem, S.A. | An improved process for the synthesis of solifenacin |
| EP2146693A2 (de) * | 2007-04-11 | 2010-01-27 | Dr. Reddy's Laboratories Ltd. | Solifenacin-zusammensetzungen |
| JP2009538362A (ja) * | 2007-07-13 | 2009-11-05 | テバ ファーマシューティカル インダストリーズ リミティド | ソリフェナシンの調製方法 |
| EP2172201A4 (de) * | 2007-07-20 | 2011-07-06 | Astellas Pharma Inc | Pharmazeutische zusammensetzung zur linderung von symptomen der unteren harnwege im zusammenhang mit prostatomegalie |
| EP2018850A1 (de) * | 2007-07-24 | 2009-01-28 | Ratiopharm GmbH | Pharmazeutische Zusammensetzung mit Solifenacin oder einem pharmazeutisch akzeptablen Salz daraus |
| PT2216021E (pt) * | 2007-11-02 | 2012-11-06 | Astellas Pharma Inc | Composição farmacêutica para tratar uma bexiga hiperactiva |
| WO2009087664A1 (en) * | 2007-12-04 | 2009-07-16 | Cadila Healthcare Limited | Process for preparing chemically and chirally pure solifenacin base and its salts |
| WO2009073203A1 (en) * | 2007-12-04 | 2009-06-11 | Amgen Inc. | Trp-m8 receptor ligands and their use in treatments |
| ITMI20080195A1 (it) | 2008-02-08 | 2009-08-09 | Dipharma Francis Srl | Procedimento per la preparazione di solifenacin |
| EP2100599A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
| EP2100598A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
| AU2009229372C1 (en) | 2008-03-27 | 2017-02-02 | Chase Pharmaceuticals Corporation | Use and composition for treating dementia |
| PL385265A1 (pl) * | 2008-05-23 | 2009-12-07 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Sposób wytwarzania solifenacyny i/lub jej soli o wysokiej czystości farmaceutycznej |
| PL385264A1 (pl) | 2008-05-23 | 2009-12-07 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Sposób wytwarzania enancjomerycznie czystej (S)-1-fenylo-1, 2, 3, 4-tetrahydroizochinoliny |
| SI3067353T1 (en) | 2008-07-29 | 2018-03-30 | Krka, D.D., Novo Mesto | Process for the preparation of solifenacin salts and their inclusion in pharmaceutical dosage forms |
| EP2181707A1 (de) | 2008-11-04 | 2010-05-05 | Astellas Ireland Co., Ltd. | Kombinierte Verwendung eines alpha-adrenergischen Rezeptorantagonisten und eines Antimuskarinmittels |
| SI2394648T1 (sl) * | 2009-02-04 | 2017-02-28 | Astellas Pharma Inc. | Farmacevtski sestavek za oralno dajanje |
| ES2753979T3 (es) | 2009-03-09 | 2020-04-15 | Megafine Pharma P Ltd | Un nuevo método para la preparación de solifenacina y nuevo intermedio de la misma |
| WO2010113840A1 (ja) | 2009-03-30 | 2010-10-07 | アステラス製薬株式会社 | ソリフェナシン非晶質体を含有した固形医薬組成物 |
| WO2011048607A1 (en) | 2009-09-25 | 2011-04-28 | Cadila Healthcare Limited | Processes for the preparation of solifenacin or a salt thereof |
| PL234208B1 (pl) | 2010-01-18 | 2020-01-31 | Zakl Farmaceutyczne Polpharma Spolka Akcyjna | Sposób wytwarzania bursztynianu solifenacyny |
| EP2554184B1 (de) | 2010-03-31 | 2016-10-26 | ONO Pharmaceutical Co., Ltd. | Mittel zur verhinderung und/oder heilung des hand-fuss-syndroms |
| EP2563123B1 (de) | 2010-04-30 | 2018-04-25 | Merck Sharp & Dohme Corp. | Neue beta-3-adrenerge rezeptoragonisten |
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| EP2590973B1 (de) | 2010-07-05 | 2016-08-31 | Crystal Pharma, S.A.U. | Solifenacin-salze |
| CA2817336A1 (en) | 2010-11-11 | 2012-05-18 | Hexal Ag | Crystalline solifenacin succinate |
| EP2510928A1 (de) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten |
| RU2671575C2 (ru) | 2011-05-10 | 2018-11-02 | Теравида, Инк. | Применение солифенацина и стимуляторов слюноотделения в лечении гиперактивного мочевого пузыря |
| WO2012175119A1 (en) | 2011-06-22 | 2012-12-27 | Isochem | Process for the preparation of solifenacin and salts thereof |
| KR101365849B1 (ko) | 2012-03-28 | 2014-02-24 | 경동제약 주식회사 | 솔리페나신 또는 그의 염의 제조방법 및 이에 사용되는 신규 중간체 |
| CN104411687A (zh) | 2012-07-02 | 2015-03-11 | 法尔玛赞公司 | 一种用于制备索非那新或其盐的方法 |
| BR112015004244A2 (pt) | 2012-08-31 | 2017-07-04 | Astellas Pharma Inc | composição médica oralmente administrada |
| KR20150048888A (ko) | 2012-09-05 | 2015-05-07 | 체이스 파마슈티칼스 코포레이션 | 항콜린 신경보호 조성물 및 그 방법 |
| CN103787969B (zh) | 2012-10-30 | 2016-07-06 | 上海京新生物医药有限公司 | 一种(1s)-1-苯基-3,4-二氢-2(1h)-异喹啉甲酸酯的制备方法 |
| WO2014086927A1 (en) * | 2012-12-06 | 2014-06-12 | Chiesi Farmaceutici S.P.A. | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| EP2778167A1 (de) | 2013-03-11 | 2014-09-17 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Stabile pharmazeutische Zubereitung enthaltend Solifenacin oder deren pharmazeutisch verträgliches Salz |
| KR101823451B1 (ko) * | 2013-07-13 | 2018-01-30 | 베이징 에프에스웰컴 테크놀로지 디벨롭먼트 컴퍼니 리미티드 | 퀴논계 화합물, 이의 광학 이성질체 및 이의 제조 방법과 의약 용도 |
| US20170065589A1 (en) | 2014-05-06 | 2017-03-09 | Anthony G. Visco | Methods of treating or preventing preterm labor |
| CN104592221A (zh) * | 2015-01-26 | 2015-05-06 | 中山奕安泰医药科技有限公司 | 一种合成索非那新的工艺 |
| KR20160146428A (ko) | 2015-06-12 | 2016-12-21 | 한미정밀화학주식회사 | 솔리페나신 또는 그의 약학적으로 허용되는 염과 락토즈를 포함하는 안정한 무정형 솔리페나신 약학 조성물 및 그의 제조방법 |
| KR102148414B1 (ko) | 2017-05-15 | 2020-08-26 | 주식회사 서울제약 | 솔리페나신을 유효성분으로 하는 구강붕해필름 |
| EP3724188B1 (de) | 2017-12-12 | 2023-06-07 | Arkuda Therapeutics | Progranulin-modulatoren und verfahren zu deren verwendung |
| ES2992256T3 (es) | 2018-05-08 | 2024-12-11 | Nippon Shinyaku Co Ltd | Compuestos de azabencimidazol y producto farmacéutico |
| US20220251084A1 (en) * | 2019-06-12 | 2022-08-11 | Arkuda Therapeutics | Progranulin modulators and methods of using the same |
| CN114929697A (zh) | 2019-11-13 | 2022-08-19 | 日本新药株式会社 | 氮杂苯并咪唑化合物和药物 |
| CN113200979A (zh) * | 2021-04-13 | 2021-08-03 | 上海予君生物科技发展有限公司 | 一种琥珀酸索非那新的合成工艺 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3687980T2 (de) * | 1986-01-07 | 1993-06-17 | Beecham Group Plc | Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen. |
| IT1231238B (it) * | 1987-09-21 | 1991-11-26 | Angeli Inst Spa | Derivati ammidinici |
| IT1228293B (it) * | 1989-02-06 | 1991-06-07 | Angeli Inst Spa | Benzoderivati di composti eterociclici contenenti azoto. |
| IT1230881B (it) * | 1989-06-20 | 1991-11-08 | Angeli Inst Spa | Derivati del r(-) 3-chinuclidinolo |
| GB9023023D0 (en) * | 1990-10-23 | 1990-12-05 | Barlow Richard B | Pharmaceutical compositions |
| GB9202443D0 (en) * | 1992-02-05 | 1992-03-18 | Fujisawa Pharmaceutical Co | A novel substituted-acetamide compound and a process for the preparation thereof |
| JPH076635A (ja) * | 1993-06-18 | 1995-01-10 | Sony Corp | 信号伝送ケーブル |
| AU7545894A (en) * | 1993-09-02 | 1995-03-22 | Yamanouchi Pharmaceutical Co., Ltd. | Carbamate derivative and medicine containing the same |
| JPH07258250A (ja) * | 1994-03-25 | 1995-10-09 | Yamanouchi Pharmaceut Co Ltd | エステル誘導体 |
| EP1424021B1 (de) * | 2002-11-27 | 2006-09-13 | Selmac S.r.l. | Vorrichtung zum Positionieren und Spannen geformter Teile und damit ausgerüstete Maschine |
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1988
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1995
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- 1995-12-27 US US08/860,377 patent/US6017927A/en not_active Expired - Lifetime
- 1995-12-27 WO PCT/JP1995/002713 patent/WO1996020194A1/ja not_active Ceased
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- 1995-12-27 RU RU97112907/04A patent/RU2143432C1/ru active Protection Beyond IP Right Term
- 1995-12-27 EP EP95942276A patent/EP0801067B1/de not_active Expired - Lifetime
- 1995-12-27 TW TW084113934A patent/TW305842B/zh not_active IP Right Cessation
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